Meet the Expert Workshop Program March 2 5, 2016, Austria Center Vienna, Room 1.61

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1 Meet the Expert Workshop Program 2016 March 2 5, 2016, Austria Center Vienna, Room 1.61

2 Wednesday, March 2 Theme 12:15 13:45 The Full Picture RDM and CDM Focus on Efficiency / M. Jopek, M. Das 14:00 15:30 Update and Understanding on Gd Deposits / V. M. Runge, H. Pietsch, A. Radbruch 16:00 17:00 Preparation for the EURATOM Directive with Insights into Dose Analytics and Protocol Optimization / M. Jopek, H. Haubenreisser, M. Wucherer Please contact your Bayer Representative for registration Thursday, March 3 Theme 10:15 11:45 Men's Health: Prostate MRI When & How? / F. Cornud, C. Kastner, U. Kramer Clear Direction. From Diagnosis to Care. More information on radiology.bayer.com Name: Signature: 12:15 13:45 Innovative Approaches in Advanced MR Liver Imaging / C. Zech, L. Grazioli, A. Ba-Ssalamah 14:00 15:30 A Dose of Reality, Arming You for Radiation Dose Management Success / F. Windham 16:00 17:30 First European Radimetrics User Group / E. Gombert, M. Jopek Friday, March 4 Theme 08:30 09:40 Innovative Choices for Diagnosing Liver and Biliary Disorders / A. Ba-Ssalamah 10:15 11:45 Personalized Care in Diagnosis / F. Maggioni, E. Gombert, M. Jopek, D. Caramella 12:15 13:45 Diagnosis and Therapy of Chronic Thromboembolic Pulmonary Hypertension Why is Radiology Crucial for Patient Management? / I. Lang, A. Huppertz, D. Gopalan, B. Meyer 14:00 15:30 Men's Health: Prostate MRI When & How? / F. Cornud, C. Kastner, U. Kramer 16:00 17:25 Discover the Innovative Quality Management Improvement within a Radiology Department / M. Jopek, A. Parakh, J. Theysohn, A. Ringelstein Saturday, March 5 Theme 10:15 11:45 Contrast Data Recording and Dose Personalization with Certegra: Real Life Experience / L. Febrer, M. del Mar Pérez, I. Vivas 12:15 13:45 About the Dose in Radiology / L. Febrer, J. Almansa 14:00 15:30 Contrast-Enhanced CT Scanning What is Really Necessary for Your Daily Practice? / J. E. Wildberger, P. B. Persson

3 Clear Direction. From Diagnosis to Care. More information on radiology.bayer.com Dear ECR participants, with your diagnosis you provide clear direction in a patient's clinical journey and thus contribute substantially to patient care every day. We at Bayer are well aware of the challenges radiologists face in a changing environment in radiology. Challenges may refer to increasing administration and economic pressure. But it can also be challenging to keep up-to-date with advances and progress in radiology. It is our goal at Bayer to support you as best as we can to facilitate your work. Not only with reliable products but also with useful services. Our commitment to education and trainings has a long tradition. In our workshop series accompanying this year s ECR, experts present innovative diagnostic imaging approaches including advanced liver and prostate MRI as well as CT-based diagnosis of chronic thromboembolic pulmonary hypertension. One focus is dedicated to informatics in radiology. With regard to the EURATOM directive to be implemented soon, we have scheduled several lectures on tracking and managing radiation dose as well as on protocol optimization. We hope that these workshops are useful for you! Your input for future workshops is highly welcome. Please don t hesitate to suggest topics you would like to see covered next time. Kind regards Your Bayer ECR team

4 Wednesday March 2 12:15 13:45 The Full Picture RDM and CDM Focus on Efficiency Presenter M. Das, Maastricht / NL M. Das from the University Hospital of Maastricht shares experience in monitoring and managing both radiation and contrast dose, using the Radimetrics Enterprise Platform. He will give an insightful focus on the efficiency gains experienced since the implementation of the system. Wednesday March 2 14:00 15:30 Update and Understanding on Gd Deposits 1 Gd deposits in preclinical perspective H. Pietsch, Berlin / DE 2 What do we know from the clinical research? A. Radbruch, Heidelberg / DE 3 Discussion M. Jopek, V. M. Runge, Bern / CH

5 Wednesday March 2 16:00 17:00 Preparation for the EURATOM Directive with Insights into Dose Analytics and Protocol Optimization 1 Structured analysis of 4D CT data with Radimetrics H. Haubenreisser, Mannheim / DE 2 Experience with Radimetrics in preparation for EURATOM Directive 2013/59 M. Wucherer, Nuremberg / DE With the increasing advent of more complex protocols with state-of-the-art CT systems, dose analysis has become more challenging. Especially with more and more frequently performed 4D dynamic angiographic studies and a more widespread use of CT perfusion techniques in clinical routine, dose analysis is essential for real-time protocol optimization. H. Haubenreisser will provide an overview of dose analysis and subsequent protocol optimization for 4D CT studies using the Radimetrics software in order to decrease radiation dose to a minimum while at the same time using the diagnostic information of advanced protocols (e.g. stroke imaging; hepatic perfusion imaging for TACE therapy planning). M. Wucherer will present experience with Radimetrics in preparation for EURATOM. The German government has to implement the Basic Safety Standards of the EU Directive 2013/59 into the national radiation protection law until M. Wucherer will present some resultant changes and consequences. Clear Direction. From Diagnosis to Care. M. Jopek, More information on radiology.bayer.com

6 Thursday March 3 10:15 11:45 Bayer / Siemens Joint Meet the Expert Workshop Men's Health: Prostate MRI When & How? 1 When? The Urologist s perspective C. Kastner, Cambridge / UK 2 How? The Radiologist s perspective U. Kramer, Tübingen / DE Prostate cancer is the second-most malignant type of cancer in men with a 5-year survival rate of 98% if detected early and treated adequately. About 14% of men will be diagnosed with prostate cancer at some point of their lifetime. MRI has been used for noninvasive assessment of the prostate gland and surrounding structures since the 1980s. Advances in technology have led to the development of multiparametric MRI (mpmri), which combines anatomic T2W with functional and physiologic assessment, including diffusion-weighted imaging (DWI) and its derivative apparentdiffusion coefficient (ADC) maps as well as dyamic contrast -enhanced (DCE) MRI. These technologic advances, combined with a growing interpreter experience and the introduction of standardized reporting (PI-RADS), have substantially improved diag nostic capabilities. This session will discuss the role of prostate MRI in the primary diagnosis and treatment follow-up of, prostatecancer as well as the technological capabilities in connection with biopsies and other imaging modalities. Thursday March 3 12:15 13:45 Innovative Approaches in Advanced MR Liver Imaging 1 Practical considerations: How can I achieve a good image quality in Primovist -enhanced liver MRI? L. Grazioli, Brescia / IT 2 Clinical files: My best Primovist cases Interactive session A. Ba-Ssalamah, Vienna / AT 3 Journal club: New evidence for hepatobiliary MRI with Primovist C. Zech, Basel / CH In this workshop L. Grazioli will discuss artifacts and challenges in the early vascular phase of liver MRI with gadoxetic acid and show solutions how to overcome these challenges for example with multiphasic arterial imaging and other techniques. A. Ba-Ssalamah will present cases of benign and malignant liver lesions giving multiple opportunities for the audience to actively participate in the discussion. C. Zech will review the newest literature in the field of contrastenhanced liver MR imaging. F. Cornud, Paris / FR C. Zech, Basel / CH

7 Thursday March 3 14:00 15:30 A Dose of Reality, Arming You for Radiation Dose Management Success Presenter F. Windham, Learn about best practices in preparing for your Dose Management Solution. Closing the gap between buying a Radiation Dose Manage ment Solution and implementing a vital tool for your organization takes the right planning, people and processes. Whether you have recently purchased or are considering a Dose Management Solution, this session will provide best practices and lessons learned from working with hundreds around the globe. The workshop will focus on the following topics: Recognizing common challenges and pitfalls Establishing governance- roles and responsibilities Account for equipment Standardizing Nomenclature Defining processes Thursday March 3 16:00 17:30 This Workshop is for all current users of Bayer's Radimetrics Enterprise Platform First European Radimetrics User Group Presenters for network ing, learn best practices and collaboration. You are at the forefront of driving dose- E. Gombert and M. Jopek, s related compliance and safety initiatives across healthcare organizations today. As a leader in You're capturing the dose information you need. these areas, we value your experience and welcome you and like-minded peers to share expe- What's next? Join us as we launch the first European Radimetrics User Group at ECR 2016! riences. Furthermore, we are available to help with questions and will focus on dose registries All current users of Bayer s Radimetrics Enterprise as the next frontier, whilst giving you the opportunity to view developments in our Platform are welcome to join this opportunity portfolio. F. Windham, M. Jopek,

8 Friday March 4 08:30 09:40 Innovative Choices for Diagnosing Liver and Biliary Disorders Presenter A. Ba-Ssalamah, Vienna / AT This is an interactive workshop offering multiple opportunities to ask questions. A. Ba-Ssalamah will briefly discuss the different modalities for liver imaging highlighting the required MR liver scanning protocols and sequences. In the second part of the workshop, the participants will learn about the role of Primovist in characterizing morphological and functional liver lesions. Friday March 4 10:15 11:45 Personalized Care in Diagnosis 1 Start simple, partner with perspective E. Gombert and M. Jopek, s 2 BayerMedical requirements in radiation dose and novel technical developments D. Caramella, Pisa / IT Still confused by radiation dose management requirements? Start simple, with the new focused Radimetrics package. It helps you to easily monitor and manage your patient radiation doses to be prepared for the changes in legislation. You can even participate in dose registries. And because it is built on the same platform as Radimetrics Enterprise Platform, you can expand into advanced contrast analytics and quality management when you are ready. That s partnership with perspective. D. Caramella focuses on the optimization of radiological procedures. Optimization of radiological procedures relies on careful monitoring and benchmarking of suitable biomarkers. D. Caramella will present his experience how automatic tracking of radiation dose and contrast agents can be used to achieve personalized precision medicine in radiology. A. Ba-Ssalamah, Vienna / AT F. Maggioni,

9 Friday March 4 12:15 13:45 Diagnosis and Therapy of Chronic Thromboembolic Pulmonary Hypertension Why is Radiology Crucial for Patient Management? 1 Introduction to pulmonary hypertension with focus on the chronic form CTEPH I. Lang, Vienna / AT 2 Diagnosis of pulmonary hypertension and CTEPH in secondary health care centers A. Huppertz, Potsdam / DE 3 Advanced pulmonary vascular imaging in the specialized PH center D. Gopalan, London / UK 4 Pulmonary angiography in CTEPH: Imaging and treatment B. Meyer, Hannover / DE This is an interactive workshop on CTEPH ( Chronic Thromboembolic Pulmonary Hypertension) as the only curable form of Pulmonary Hypertension and the importance of identifying CTEPH pat ients timely with the appropriate imaging modalities. The workshop will focus in the following subjects: What is CTEPH? Overview on the disease The reason why radiologists play a decisive role in patient management What the different imaging modalities can offer both in Secondary and in Specialized Hospitals Therapeutic options for CTEPH patients Friday March 4 14:00 15:30 Bayer / Siemens Joint Meet the Expert Workshop Men's Health: Prostate MRI When & How? 1 When? The Urologist s perspective C. Kastner, Cambridge / UK 2 How? The Radiologist s perspective U. Kramer, Tübingen / DE Prostate cancer is the second-most malignant type of cancer in men with a 5-year survival rate of 98% if detected early and treated adequately. About 14% of men will be diagnosed with prostate cancer at some point of their lifetime. MRI has been used for noninvasive assessment of the prostate gland and surrounding structures since the 1980s. Advances in technology have led to the development of multiparametric MRI (mpmri), which combines anatomic T2W with functional and physiologic assessment, including diffusion-weighted imaging (DWI) and its derivative apparentdiffusion coefficient (ADC) maps as well as dyamic contrast -enhanced (DCE) MRI. These technologic advances, combined with a growing interpreter experience and the introduction of standardized reporting (PI-RADS), have substantially improved diag nostic capabilities. This session will discuss the role of prostate MRI in the primary diagnosis and treatment follow-up of, prostatecancer as well as the technological capabilities in connection with biopsies and other imaging modalities. I. Lang, Vienna / AT F. Cornud, Paris / FR

10 Friday March 4 16:00 17:25 M. Jopek, Discover the Innovative Quality Management Improvement within a Radiology Department 1 Achieving CT dose reduction in clinical routine using radiation tracking software A. Parakh, Basel / CH 2 Practical and scientific results after 2 ½ years Radimetrics in Essen J. Theysohn and A. Ringelstein, Essen / DE A. Parakh from the University Hospital of Basel reports experiences with the automatic dose tracking software Radimetrics. Comparing protocols and modalities and analyzing dataset outliers made it possible to identify the reasons for high dose variations between examinations. By optimizing these factors based on the collected data the institution was able to significantly reduce the average radiation doses. In addition, automatic outlier alerts given by the software greatly improved patient safety. J. Theysohn and A. Ringelstein from the University Hospital Essen give insight into lessons learned following the installation of Radimetrics 2 years ago. This tool has enabled them to understand the nature of dose generation distribution in patients, which has resulted in the implementation of major dose reductions. The information gathered from the system has allowed the institution to become instru mental in identifying areas of interest which has resulted in various scientific projects; from comparing calculated dose values to phantom measurements, to understanding dose exposition through native liver imaging, to dose reduction facilitated through the use of modern low-dose scanners or protocols. Clear Direction. From Diagnosis to Care. More information on radiology.bayer.com

11 Saturday March 5 10:15 11:45 Contrast Data Recording and Dose Personalization with Certegra: Real Life Experience Presenters M. del Mar Pérez, Asturias / ES I. Vivas, Navarra / ES Contrast dose management is important to find the right balance between image quality and proper injection parameters to improve patient care. Clearly, overdosing patients can lead to increased rate of adverse events and underdosing them can cause suboptimal diagnostic capacity of the procedure. Dose personalization means administering each patient the adequate dose, taking into account the procedure to be performed, patient characteristics and its history. Also, the possibility to diagnose, having data on the injection together with procedure images, is the basis for adequately informed decision making. Saturday March 5 12:15 13:45 The session will be held in Spanish About the Dose in Radiology Presenters J. Almansa, Granada / ES L. Febrer, As we approach the deadline for transposing the EURATOM directive 59/2013 across the European countries, the session aims at putting some focus in the practical aspects of dose management in radiology from different perspectives within the Spanish context. This will be done by means of sharing opinions, experiences and new approaches of two experts on the topic, a radiologist and a medical physicist, working both in the private and the public setting. L. Febrer, L. Febrer,

12 Saturday March 5 14:00 15:30 J. E. Wildberger, Maastricht / NL Contrast-Enhanced CT Scanning What is Really Necessary for Your Daily Practice? 1 Contrast media application Obtaining robust enhancement patterns in daily practice J. E. Wildberger, Maastricht / NL 2 Understanding the underlying mechanisms of adverse drug reactions and how to identify and treat patients at risk P. B. Persson, Berlin / DE What is important to know for your daily contrastenhanced CT examinations? This very inter active session will address and bring together two important topics with respect to contrast-enhanced CT imaging. Firstly, how to standardize and individualize contrast media delivery to obtain robust image quality that always allows for reliable diagnoses. Secondly, be aware of patients safety and know the properties and risks of contrast agents. J. E. Wildberger has published several peer-reviewed articles on the topic image quality. In his talk he will present the most important aspects to obtain contrast-enhanced images of high quality and provide further information on how to optimize image quality. P. B. Persson is one of the world s leaders in i nvestigating the underlying mechanism of contrast-induced nephropathy (CIN). P. B. Persson published many articles that helped to understand CIN and provide suggestions on how to minimize the risk. However, in his talk, P. B. Persson will not only focus on CIN but also present the underlying mechanisms of other adverse reactions that can occur with iodinated contrast media. The discussion at the end will bring both topics together and provide time to answer questions that often come up in daily practice. Clear Direction. From Diagnosis to Care. More information on radiology.bayer.com

13 If you are interested in any other workshops, please contact your for registration. Bayer Pharma AG Berlin, Germany More information on radiology.bayer.com G.MKT.RI L.AT.MKT January 2016

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