Evidence Evolution. Any Test, Any Time

Transcription

1 Evidence Evolution Any Test, Any Time

2 About the Evidence Evolution The Evidence Evolution sets new standards in diagnostic testing, bringing unrivalled versatility, quality and efficiency to deliver precise results quickly and economically. Widely used across the world for fifteen years, multiplex testing with our patented Biochip Array Technology provides a complete patient profile from a single sample, ensuring a rapid and accurate diagnosis.

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4 Benefits Dimensions Weight 1320 (H) x 1200 (D) x 1675 (W) mm 720 kg, 1587 lbs

5 Any Test, Any Time Evidence Evolution is a highly versatile analyser which can process any required workflow including batch analysis, STAT samples and true random access. Fast Turnaround Time Capability to achieve 2640 test results per hour with the Evidence Evolution, with first sample result reported in <36 minutes and up to 44 results reported every minute thereafter. Dedicated R&D Randox research and development teams are continually evolving our test menu, which covers a variety of disease areas including oncology, cardiology and neurology. Cost Consolidation Multiplex technology allows numerous tests to be performed from a single patient sample, reducing the amount of time and labour spent on individual tests, while also providing a complete patient profile. $ Superior Intelligence Features such as automatic start-up and shut down, reflex testing capabilities and traceability of biochips and reagents, ensures the Evidence Evolution can be tailored to your laboratory needs. Enhanced User Experience Highly intuitive software, customisable user settings and easy to follow result screens ensures usability, allowing laboratories to achieve fast and accurate operations with uncompromised quality. Workflow Optimisation With continuous sample and reagent loading, alongside automated on-board sample dilution and sample information entry; the Evidence Evolution, with a walk away time of 2 hours, is a convenient solution for busy laboratories.

6 TEST MENU Clinical Arrays Thyroid Array Thyroid Auto Antibody Array Thyroid Thyroid Stimulating Hormone TSH Free Thyroxine FT4 Free Triidothyronine FT3 Anti-Thyroid Peroxidase Anti-TPO Anti-Thyroglobulin Anti-Tg Thyroid TBG Assay Thyroxine Binding Globulin TBG Fertility Array Fertility Testosterone Assay Testosterone Luteinizing Hormone LH Follicle Stimulating Hormone FSH Progesterone Prolactin Estradiol SHBG Assay Sex Hormone Binding Globulin SHBG Tumour PSA Array Cardiac Array Endocrine Array Anaemia Array Oncology Total Prostate Specific Antigen TPSA Free Prostate Specific Antigen FPSA Carcinoembryonic Antigen CEA Cardiac Heart Fatty Acid Binding Protein H-FABP Cardiac Troponin I ctni Creatine Kinase MB CKMB Endocrine Cortisol Dehydroepiandrosterone-Sulphate DHEAS Anaemia Vitamin B12 Folate Bone Vitamin D Assay Vitamin D Gastropanel Array Gastro-Intestinal Pepsinogen I PGI Pepsinogen II PGII Gastrin 17 G17 Helicobacter pylori Assay Helicobacter pylori H. pylori

7 Clinical Arrays Stroke Array Chronic Kidney Disease Array I Chronic Kidney Disease Array II Apo E4 Array Metabolic Syndrome Array Cytokine Array Adhesion Molecule Array Stroke Glial Fibrillary Acidic Protein GFAP Glutathione S Transferase P GSTPi Heart Fatty Acid Binding Protein H-FABP Interleukin-6 IL-6 Nucleoside Diphosphate Kinase NDKA D Dimer Parkinson Protein 7 PARK-7 Soluble Tumour Necrosis Factor Receptor 1 stnfr1 Renal Fatty Acid Binding Protein-1 FABP1 Soluble Tumour Necrosis Factor Receptor 1 stnfr1 Soluble Tumour Necrosis Factor Receptor 2 stnfr2 Macrophage Inflammatory Protein-1α MIP-1α Adiponectin Complement C3a des Arginine C3a des Arg C-Reactive Protein CRP Neutrophil Gelatinase-Associated Lipocalin NGAL Cystatin C Alzheimer s Disease Pan Apolipoprotein E Apo E Apolipoprotein E4 Apo E4 Metabolic Syndrome Ferritin Insulin Leptin Resistin Plasminogen Activator Inhibitor PAI-1 Inflammation Interleukin-1α IL-1α Interleukin-1β IL-1β Interleukin-2 IL-2 Interleukin-4 IL-4 Interleukin-6 IL-6 Interleukin-8 IL-8 Interleukin-10 IL-10 Vascular Endothelial Growth Factor VEGF Epidermal Growth Factor EGF Tumour Necrosis Factor-α TNF-α Interferon-γ IFN-γ Monocyte Chemotactic Protein-1 MCP-1 Intercellular Adhesion Molecule-1 ICAM-1 Vascular Cell Adhesion Molecule-1 VCAM-1 E-Selectin P-Selectin L-Selectin

8 Evidence Evolution Process Step 1 Step 2 Step 3 Initialise analyser, user loads biochips, reagents and samples Assay diluent, sample & conjugate dispensed into biochip well Biochip incubated Step 6 Step 5 Step 4 Biochip loaded into image box and chemiluminescence measured Signal reagent dispensed into biochip well Biochip washed Key User Step Analyser Step Step 7 Test results reported

9 Technical Specifications Access Loading Aspiration Capability Biochip Format Biochip Capacity Calibration Principal Connectivity Data Backup Methods Data Storage Capacity Environment Liquid Waste LIS Connectivity Maximum Throughput Measurement Principal Network Services Operational Modes Operator Interface Quality Control Reagent Capacity Sample Barcode Sample Capacity Sample Dilution Sample Tube Compatibility Sample Wedges Sample Volume System Fluids Time to First Result Walk-away Time Continuous sample, reagent and biochip input and output Includes precision pump, liquid level detection and clot detection When processing 44 analytes per biochip, 2640 tests can be carried out per hour Cartridge format with 10 x single biochip, individually sealed wells 6 point with 4 parameter fitting curve generation 6 x USB ports, 1 x Ethernet, 1 x RS232 Via writable DVD, CD, USB mass-storage or network folder Up to 12 million test results with complete raw data. RAID 1 data mirroring Ambient environment 18 C-30 C, <2 C temperature variation per hour, 20%-85% relative humidity High and low concentration waste separation Bi-directional: ASTM Standard (RS232 Connection) 60 samples per hour Chemiluminesence Highly secure remote diagnostics, automated software update and array updates Random and continuous access, STAT loading with no dedicated loading route required, batch mode 22 touch screen monitor, highly intuitive e-touch software Interactive Levey-Jennings, user definable multipoint rules with system alarm 20 twin vessel reagent bottles (50ml per vessel) Code 39, Codabar, Code 128, I 2 of 5, Code 93, UPC/EAN, Pharmacode, PDF417(option), MicroPDF(option) 120 Samples Automatic, on-board dilution, continuously variable between 1:1 and 1:50, array dependent 1-2ml paediatric cups, standard sample tubes (D mm x H mm), Cobus cups (using optional adaptors) 10 Independent wedges holding 12 samples each. Each wedge can hold any combination of sample tubes Array dependent Onboard dilution of bulk reagents, refrigerated storage, continuous level monitoring Approximately 36 minutes, with 1 result every minute after (array specific) 2 hours

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11 Biochip Array Technology Moving away from traditional single analyte assays, Biochip Array Technology (BAT) boosts cutting edge multiplex testing capabilities. Our technology facilitates the simultaneous quantitative or qualitative detection of a wide range of analytes, providing a rapid and accurate diagnosis from a single patient sample. As well as having time and cost saving benefits, which drive towards an increase in clinical performance, testing for multiple markers gives a more comprehensive picture of a patient s condition. Testing Process BAT is an immunoassay testing platform for the simultaneous multi-analyte testing of a panel of related tests. The technology works by combining a panel of up to 44 related tests on a single biochip with a single set of reagents, controls and calibrators. Competitive and sandwich chemiluminescent immunoassays are employed for the biochip arrays. Light signal generated from each of the test regions on the biochip is simultaneously detected using digital imaging technology and compared to that from a calibration curve.

12 #JoinTheEvolution Randox Biosciences LT693 MAR17