SAFETY DATA SHEET. Creation Date 22-Sep-2009 Revision Date 18-Jan-2018 Revision Number Identification

Transcription

1 SAFETY DATA SHEET Creation Date 22-Sep-2009 Revision Number 4 Product Name 1. Identification Tributyl phosphate Cat No. : B404-4; B CAS-No Synonyms TBP Recommended Use Uses advised against Laboratory chemicals. Not for food, drug, pesticide or biocidal product use Details of the supplier of the safety data sheet Company Fisher Scientific One Reagent Lane Fair Lawn, NJ Tel: (201) Emergency Telephone Number CHEMTRECÒ, Inside the USA: CHEMTRECÒ, Outside the USA: Hazard(s) identification Classification This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR ) Acute oral toxicity Category 4 Skin Corrosion/irritation Category 2 Serious Eye Damage/Eye Irritation Category 2 Carcinogenicity Category 2 Label Elements Signal Word Warning Hazard Statements Harmful if swallowed Causes skin irritation Causes serious eye irritation Suspected of causing cancer Page 1 / 7

2 Precautionary Statements Prevention Obtain special instructions before use Do not handle until all safety precautions have been read and understood Use personal protective equipment as required Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product Wear eye/face protection Response IF exposed or concerned: Get medical attention/advice Skin IF ON SKIN: Wash with plenty of soap and water If skin irritation occurs: Get medical advice/attention Take off contaminated clothing and wash before reuse Eyes IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing If eye irritation persists: Get medical advice/attention Ingestion IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell Rinse mouth Storage Store locked up Disposal Dispose of contents/container to an approved waste disposal plant Hazards not otherwise classified (HNOC) Harmful to aquatic life with long lasting effects 3. Composition/Information on Ingredients Component CAS-No Weight % Tributyl phosphate >95 4. First-aid measures General Advice Eye Contact Skin Contact Inhalation Ingestion Most important symptoms and effects If symptoms persist, call a physician. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention. Wash off immediately with plenty of water for at least 15 minutes. If skin irritation persists, call a physician. Move to fresh air. If not breathing, give artificial respiration. Get medical attention if symptoms occur. Clean mouth with water and drink afterwards plenty of water. None reasonably foreseeable. Page 2 / 7

3 Notes to Physician Suitable Extinguishing Media Unsuitable Extinguishing Media Treat symptomatically 5. Fire-fighting measures Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Flash Point C / F Method - Autoignition Temperature 400 C / 752 F Explosion Limits Upper Lower Sensitivity to Mechanical Impact Not impact sensitive Sensitivity to Static Discharge Specific Hazards Arising from the Chemical Keep product and empty container away from heat and sources of ignition. Hazardous Combustion Products Carbon monoxide (CO) Carbon dioxide (CO2) Oxides of phosphorus Phosphorus trihydride (phosphine) Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. NFPA Health 3 Flammability 1 Instability 0 Physical hazards N/A Personal Precautions Environmental Precautions 6. Accidental release measures Use personal protective equipment. Ensure adequate ventilation. Should not be released into the environment. Do not flush into surface water or sanitary sewer system. Methods for Containment and Clean Keep in suitable, closed containers for disposal. Soak up with inert absorbent material. Up Handling Storage Exposure Guidelines 7. Handling and storage Wear personal protective equipment. Ensure adequate ventilation. Avoid ingestion and inhalation. Do not get in eyes, on skin, or on clothing. Keep in a dry, cool and well-ventilated place. Keep container tightly closed. Keep in properly labeled containers. Keep away from direct sunlight. Keep away from oxidizing agents. 8. Exposure controls / personal protection Component ACGIH TLV OSHA PEL NIOSH IDLH Mexico OEL (TWA) Tributyl phosphate TWA: 5 mg/m 3 (Vacated) TWA: 0.2 ppm (Vacated) TWA: 2.5 mg/m 3 TWA: 5 mg/m 3 IDLH: 30 ppm TWA: 0.2 ppm TWA: 2.5 mg/m 3 TWA: 0.2 ppm TWA: 2.5 mg/m 3 STEL: 0.4 ppm STEL: 5 mg/m 3 Legend Page 3 / 7

4 ACGIH - American Conference of Governmental Industrial Hygienists OSHA - Occupational Safety and Health Administration NIOSH IDLH: The National Institute for Occupational Safety and Health Immediately Dangerous to Life or Health Engineering Measures Ensure adequate ventilation, especially in confined areas. Ensure that eyewash stations and safety showers are close to the workstation location. Personal Protective Equipment Eye/face Protection Skin and body protection Respiratory Protection Hygiene Measures Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR or European Standard EN166. Long sleeved clothing. Follow the OSHA respirator regulations found in 29 CFR or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Handle in accordance with good industrial hygiene and safety practice. 9. Physical and chemical properties Physical State Liquid Appearance Colorless Odor Odorless Odor Threshold ph Melting Point/Range -79 C / F Boiling Point/Range 289 C / F Flash Point C / F Evaporation Rate Flammability (solid,gas) Flammability or explosive limits Upper Lower Vapor Pressure Vapor Density Specific Gravity Solubility Partition coefficient; n-octanol/water Autoignition Temperature 400 C / 752 F Decomposition Temperature 177 C Viscosity Molecular Formula C12 H27 O4 P Molecular Weight Stability and reactivity Reactive Hazard Stability Conditions to Avoid Incompatible Materials None known, based on information available Stable under normal conditions. Temperatures above 146 C. Incompatible products. Protect from water. Strong oxidizing agents, Bases Hazardous Decomposition Products Carbon monoxide (CO), Carbon dioxide (CO2), Oxides of phosphorus, Phosphorus trihydride (phosphine) Page 4 / 7

5 Hazardous Polymerization Hazardous Reactions Acute Toxicity. None under normal processing. 11. Toxicological information Product Information Component Information Component LD50 Oral LD50 Dermal LC50 Inhalation Tributyl phosphate LD50 = 1390 mg/kg ( Rat ) LD50 > mg/kg ( Rabbit ) LC50 = mg/l ( Rat ) 4 h LC50 = 28 g/m 3 ( Rat ) 1 h Toxicologically Synergistic Products Delayed and immediate effects as well as chronic effects from short and long-term exposure Irritation Sensitization Carcinogenicity Irritating to eyes and skin Limited evidence of a carcinogenic effect. Component CAS-No IARC NTP ACGIH OSHA Mexico Tributyl phosphate Not listed Not listed A3 Not listed Not listed ACGIH: (American Conference of Governmental Industrial Hygienists) A1 - Known Human Carcinogen A2 - Suspected Human Carcinogen A3 - Animal Carcinogen ACGIH: (American Conference of Governmental Industrial Hygienists) Mutagenic Effects Not mutagenic in AMES Test Reproductive Effects Developmental Effects Teratogenicity STOT - single exposure STOT - repeated exposure Aspiration hazard Symptoms / effects,both acute and delayed Endocrine Disruptor Information Other Adverse Effects... None known None known The toxicological properties have not been fully investigated. Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting. May cause respiratory irritation. May be harmful if swallowed. 12. Ecological information Ecotoxicity Do not empty into drains. Do not flush into surface water or sanitary sewer system. The product contains following substances which are hazardous for the environment. Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. Contains a substance which is:. Toxic to aquatic organisms. Component Freshwater Algae Freshwater Fish Microtox Water Flea Tributyl phosphate EC50: = 4.4 mg/l, 96h LC50: = 9.6 mg/l, 96h static Not listed EC50: mg/l, 48h Page 5 / 7

6 (Pseudokirchneriella subcapitata) EC50: = 1.1 mg/l, 72h (Desmodesmus subspicatus) (Oryzias latipes) LC50: = 4.2 mg/l, 96h static (Oncorhynchus mykiss) LC50: = 13 mg/l, 96h flow-through (Oncorhynchus mykiss) LC50: mg/l, 96h flow-through (Pimephales promelas) LC50: mg/l, 96h static (Pimephales promelas) LC50: = 4.5 mg/l, 96h (Oryzias latipes) LC50: = 8.18 mg/l, 96h (Pimephales promelas) Static (Daphnia magna) Persistence and Degradability Bioaccumulation/ Accumulation. Mobility. Component log Pow Tributyl phosphate 2.5 Waste Disposal Methods DOT TDG IATA IMDG/IMO 13. Disposal considerations Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. Chemical waste generators must also consult local, regional, and national hazardous waste regulations to ensure complete and accurate classification. 14. Transport information 15. Regulatory information All of the components in the product are on the following Inventory lists: X = listed International Inventories Component TSCA DSL NDSL EINECS ELINCS NLP PICCS ENCS AICS IECSC KECL Tributyl phosphate X X X X X X X Legend: X - Listed E - Indicates a substance that is the subject of a Section 5(e) Consent order under TSCA. F - Indicates a substance that is the subject of a Section 5(f) Rule under TSCA. N - Indicates a polymeric substance containing no free-radical initiator in its inventory name but is considered to cover the designated polymer made with any free-radical initiator regardless of the amount used. P - Indicates a commenced PMN substance R - Indicates a substance that is the subject of a Section 6 risk management rule under TSCA. S - Indicates a substance that is identified in a proposed or final Significant New Use Rule T - Indicates a substance that is the subject of a Section 4 test rule under TSCA. XU - Indicates a substance exempt from reporting under the Inventory Update Rule, i.e. Partial Updating of the TSCA Inventory Data Base Production and Site Reports (40 CFR 710(B). Y1 - Indicates an exempt polymer that has a number-average molecular weight of 1,000 or greater. Y2 - Indicates an exempt polymer that is a polyester and is made only from reactants included in a specified list of low concern reactants that comprises one of the eligibility criteria for the exemption rule. U.S. Federal Regulations Page 6 / 7

7 TSCA 12(b) SARA 313 SARA 311/312 Hazard Categories CWA (Clean Water Act) Clean Air Act See section 2 for more information OSHA Occupational Safety and Health Administration CERCLA California Proposition 65 This product does not contain any Proposition 65 chemicals U.S. State Right-to-Know Regulations Component Massachusetts New Jersey Pennsylvania Illinois Rhode Island Tributyl phosphate X X X X X U.S. Department of Transportation Reportable Quantity (RQ): DOT Marine Pollutant DOT Severe Marine Pollutant N N N U.S. Department of Homeland Security This product does not contain any DHS chemicals. Other International Regulations Mexico - Grade Prepared By Creation Date Revision Date Print Date Revision Summary 16. Other information Regulatory Affairs Thermo Fisher Scientific EMSDS.RA@thermofisher.com 22-Sep Jan Jan-2018 This document has been updated to comply with the US OSHA HazCom 2012 Standard replacing the current legislation under 29 CFR to align with the Globally Harmonized System of Classification and Labeling of Chemicals (GHS). Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text End of SDS Page 7 / 7