Your home of INNOVATION. YEAR, Legal owner

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1 Your home of INNOVATION 1

2 Gambro s portfolio Chronic Care HD, HDF, Water, Vascular access, Myeloma Kidney Therapy Acute Care Kidney, Liver, Fluid overload, Sepsis System integration for improved outcome Complete system for demanding situations 2

3 Operations footprint Lund Minneapolis Rostock Hechingen Prerov Tijuana Opelika Meyzieu Sondalo Yongin Daytona Medolla Shanghai 13 Manufacturing locations Dialyzers Bloodlines Monitors Solutions Catheters 3

4 History and Innovation Milestones Launch of the system 2008 GAMBRO group starts a huge industrial reinforcement; new infrastructures are built at DASCO to support the production for the US market GAMBRO takes over HOSPAL and COBE in Both companies keep their own structures and autonomy holding separate brands in the hemodialysis market The joint venture between SANDOZ and RHÔNE POULENC leads to the establishment of HOSPAL- DASCO S.p.A. SANDOZ Swiss Pharmaceutics group acquires DASCO Dott. Mario Veronesi establishes DASCO (Dialysis Apparatus Scientific Company) and starts the production of haemodialysis machines, changing the name of an existing biomed. company, Miraset (1962) then Sterilplast (1964) Prismaflex Phoenix Integra Monitral DAS 205 DAS 203 Miraset/Sterilplast 4

5 Engineering intensive industrial network Key facts: DIDECO Synergy between R&D, Manufacturing, Logistics, Sales, Customer (Italy) Technical and clinical background Proven FDA Quality System Competence on integrated system development (monitor + disposable) Motivation and Accountability COVIDIEN B BRAUN BELLCO GAMBRO Competitive Biomedical district, with also knowhow transfer from mechanic and plastic industries Bologna and Modena Universities nearby Direct collaboration with clinics and nephrologists in Italy FRESENIUS 5

6 GAMBRO Dasco Medolla (before earthquake) Filmato 6

7 Earthquake situation Key facts before EQ: IT footprint Approx 1000 PC s Internally hosted As400 based ERP Approx 50 Wintel servers (virtual and physical) Network and Data Centre@Medolla Business 2 factories + 1 large warehouse in Medolla 2 remote factories + Commercial Op s Approx 30,000 pallets One Big Site Key facts after EQ: IT footprint Approx 1000 PC s IBM Housed As400 based ERP Approx 50 Wintel servers (90% virtual) Network centre@modena Data Centre@Modena/Lund Business 4 remote factories Externalized warehouse Approx 30,000 pallets Network 7

8 Key Organization reactions/measures Contingency strategy: Contingency team (on corporate level) Contingency subteams by issues/functions Contingency call (daily) Contingency subcalls on single issues/functions Close collaboration with Vigili/Protezione Civile and specialist salvage companies National Workgroup: Mirandola MedTech companies, Assobiomedica, Regione Emilia-Romagna, Ministero della Salute/ SIN (Italian Society of Nephrology) / Hospitals-clinics Footprint Starting footprint Emergency footprint Interim footprint End state footprint Resiliance Home working - Laptops/cell phones to all key staff Distribute workload Involve in controlled manner Group functions/colleagues Manage Stabilization/Consolidation processes as projects (responsible, timeline, budget) Focus that all processes followed from Day1 (Top/Down governance) Key lessons learned Need to think of Nuclear Attack, can t analyze/remediate every specific risk to ensure Business Continuity Employment law is never suspended no hero s Every morning does anybody have bigger problems at home than we have here? Updated/reliable documentation/inventory of systems, hardware, PC s, cabling, licenses, users Need to leverage your partners Think outside of the box (who can help?) 1. ONLY YOUR PEOPLE CAN DO IT IN A FAST, SMART, EFFECTIVE WAY SO YOU NEED TO ENABLE THEM 2. BACKUP IS KING 8

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