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1 Billing Information Payment Method Credit Card Details Sample(s) from: Collection Date 28-Jun-2017 Nan Robinson Visa 0233 NULL Arrival Date 28-Jun-2017 Approval Date 13-Jul-2017 Protocol HM Standard - Rabbits (HM-HM-203) Diagnostic Summary Test Colony Tested + +/-? PDG Gross Necropsy Exam n/d Summary Remarks + = Positive, +/- = Equivocal,? = Indeterminate, PDG = Pending Pathology Lesions were noted on gross postmortem examination. Tissues were collected for histologic examination. Pathology Tissues were submitted for histologic examination. A separate report is attached. To assure the SPF status of your research animal colonies, it is essential that you understand the sources, pathobiology, diagnosis and control of pathogens and other adventitious infectious agents that may cause research interference. We have summarized this important information in infectious agent Technical Sheets, which you can view by visiting Page 1 of 9

2 Bacteriology Results approved by Cleasby, Danielle on 05 Jul 2017 Rabbit Bronchial Wash Culture B. bronchiseptica - - K. oxytoca - - K. pneumoniae - - P. multocida - - P. pneumotropica - - Pasteurella sp. - - Ps. aeruginosa - - Pseudomonas sp. - - Staph. aureus - - Strep. pneumoniae - - Beta Strep. pyogenes - Grp A - - Beta Strep. sp. - Grp B - - Beta Strep. sp. - Grp G - - Beta Strep. sp. - - Other - - Rabbit Nasal Aspirate Culture B. bronchiseptica - - K. oxytoca - - K. pneumoniae - - P. multocida - - P. pneumotropica - - Pasteurella sp. - - Ps. aeruginosa - - Pseudomonas sp. - - Staph. aureus - - Strep. pneumoniae - - Beta Strep. pyogenes - Grp A - - Beta Strep. sp. - Grp B - - Beta Strep. sp. - Grp G - - Beta Strep. sp. - - Other - - Cecum Culture Page 2 of 9

3 Bacteriology Results approved by Cleasby, Danielle on 05 Jul 2017 Ps. aeruginosa - - Pseudomonas sp. - - Salmonella sp. - - Other - - Remarks - = Negative/No Growth; 1 = Rare/Few Colonies; 2 = Several Colonies; 3 = Moderate Growth; 4 = Heavy Growth; NI = Not Interpreted: culture could not be interpreted due to overgrowth of Proteus; NT = Not Tested. Page 3 of 9

4 Page 4 of 9

5 Health Monitoring: Parasitology Ectoparasite Direct Exam - Rabbit Results approved by Parkinson, Christina on 30 Jun 2017 Cheyletiella parasitovorax - - Leporacarus gibbus - - Other Ectoparasite - - Ectoparasite Ear Exam - Rabbit Psoroptes cuniculi - - Other Ectoparasite - - Endoparasite Exam Rabbit - Helminths Passalurus ambiguus - - Other Helminth - - Endoparasite Exam Rabbit - Protozoa Chilomastix sp. - - Eimeria stiedae - - Eimeria spp. - - Entamoeba sp. - - Giardia sp. - - Hexamastix sp. - - Trichomonads - - Retortamonas sp. - - Other Protozoan - - Fecal Centrifugation Rabbits Page 5 of 9

6 Health Monitoring: Parasitology Passalurus ambiguus - - Chilomastix sp. - - Cryptosporidium sp. - - Eimeria stiedae - - Eimeria spp. - - Entamoeba sp. - - Giardia sp. - - Retortamonas sp. - - Other Helminth - - Other Protozoan - - Remarks - = Negative; + = Positive. Results approved by Parkinson, Christina on 30 Jun 2017 Page 6 of 9

7 Health Monitoring: Pathology Results approved by Parkinson, Christina on 30 Jun 2017 Gross Necropsy Exam AB - Tyzzer's Disease - - Dermatophytosis - - Remarks - = No significant findings. A = Heart: Discoloration, white, multifocal, mild. B = Lung (All lobes): Pale, diffuse, minimal with gray, multifocal discoloration, minimal. Page 7 of 9

8 Serology Results approved by Castillo, Luz on 30 Jun 2017 MFIA ECUN - - MFIA CARB - - RPR TREP - - MFIA Anti-Ig P P Serology Profile: MFIA Rabbit Tracking Remarks IFA Results: - = Negative; +/- = Equivocal; + = Moderate to strong positive; TC = Non-specific reaction with tissue control. All Assays: IN = positive result interpreted as non-specific because not confirmed by other serologic assays, PDG = pending, QNS = Quantity not sufficient. Page 8 of 9

9 Sample Information Number Code Species Colony 1 B1 Rabbit n/d 2 B8 Rabbit n/d Page 9 of 9

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