The Current Investment Highlights of US National Nanotechnology Initiative

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1 The Current Investment Highlights of US National Nanotechnology Initiative Hongda Chen, Ph.D. National Institute of Food and Agriculture (NIFA) U.S. Department of Agriculture (USDA) July 17, 2010, Chicago, IL The views expressed in this presentation are those of the presenter and not necessarily those of the United States Government or the presenter s agency

2 Outline What is the U.S. Government s National Nanotechnology Initiative (NNI)? Overview of the NNI Budget and Investments Potential environmental, health, and safety (EHS) and other regulatory considerations How can industry tap into the benefits of nanotechnology and utilize the results of NNIfunded research? Education, public communication and engagement, perception and acceptance

3 NIST NASA DOD NIH OSTP OMB NSF DOE FDA USDA/ NIFA NIOSH DOS National Nanotechnology Initiative Collaborative, Multi-agency, Cross-cut Program Among 25 Federal agencies, 15 of which have specific nanotechnology budgets USDA FS EPA DOTr DOT Funds R&D to advance understanding and control of matter at nanoscale toward: National economic benefit NRC USPTO ITIC National and homeland security Improved quality of life DOL USGS DOJ DOC BIS DHS CPSC ITC DOEd

4 The National Nanotechnology Initiative: vision and goals The vision of the NNI: a future in which the ability to understand and control matter on the nanoscale leads to a revolution in technology and industry that benefits society Four goals for nanoscale science, engineering, and technology, as described in the NNI's Supplement to the President's FY 2011 Budget and 07 Strategic Plan: Advance a world-class research and development program Foster technology transfer for commercial & public benefit Develop & sustain educational resources, a skilled workforce, and the supporting research infrastructure and tools Support responsible development of nanotechnology

5 Broad brush view of NNI operations Management EOP + Agencies Establishment of nanotechnology as high priority R&D area Budget creation and funding allocation to agencies Negotiations with Congress Coordination NSET Subcommittee Coordinates development of strategic plan for NNI Providing mechanisms for interagency communication and coordination on nanotechnology R&D Reporting NNCO Publishes reports on behalf of the NSET and the NNI for use by Congress, academia, industry, and the public Serves as central public point of contact for NNI

6 NNI budget information NNI expenditures* have grown from $464 million in FY 01 to an FY 11 request of nearly $1.8 billion.** $2,000 $1,800 $1,702 $1,781 $1,762 $1,600 $1,400 $1,351 $1,424 $1,555 $1,200 $1,200 $1,000 $989 $800 $697 $760 $600 $400 $464 $200 $ * All numbers shown above are actual spending, except 2010, which is estimated spending for the current year and 2011, which is requested amount for next year (FY 09 figure shown here does not include ~$500 million in additional ARRA funding). ** 2011 figure shown here does not include DOD earmarks included in previous yrs. ($117 M 09)

7 International nanotech R&D investment New announcements from Russia and EU recently indicate very large new investments U.S. estimate for 2010 is $1.78 billion; 2011 request is ~$1.76 billion Source: M. C. Roco, NSF

8 NNI Support for Innovation Cumulative NNI investment of nearly $14 billion (including the President s request for 2011) Advanced foundational knowledge for control of matter at the nanoscale with over 4500 research projects in all 50 states Developed an extensive infrastructure of interdisciplinary research centers, networks and user facilities distributed across the country Invested significantly in nanotechnology-related EHS R&D to date and anticipate continuing targeted increases Established major networks for developing public awareness of nanotechnology and formal educational programs Organized and conducted 16 workshops on cross-cutting areas of nanotechnology applications

9 NNI activities and documents inform agencies, report outcomes, and serve as resources NEW: Supplement to the President's FY 2011 Budget General brochure for a broad audience NNI Strategic Plan

10 NNI budget by agency, Agency 2009 Actual 2009 Recovery* 2010 Estimated 2011 Proposed DOE NSF HHS/NIH DOD** DOC/NIST EPA HHS/NIOSH NASA HHS/FDA DHS USDA/NIFA USDA/FS CPSC DOT/FHWA DOJ TOTAL 1, , ,761.6 * Based on allocations ARRA appropriations. Agencies may report additional ARRA funding for SBIR and STTR projects later. ** 2009 and 2010 DOD figures include Congressionally directed funding that is outside the NNI plan ($117 million for 2009). See NNI Supplement to the President s FY 11 Budget for additional details:

11 USDA/NIFA Expenditure in Nanotechnology

12 AFRI: Nanoscale Science and Engineering FY 2009 Priorities Anticipated Major Changes in FY 2010 Nanoscale recognition, reception, and transmission mechanisms and novel materials for developing nano-based sensors specifically for targets important to food safety and agriculture biosecurity. Novel nanoscale processes, materials, and systems with improved delivery efficacy, controlled release, modification of sensory attributes, and protection of micronutrients and functional ingredients suitable for food matrices. Understanding nanoscale phenomena and processes to support the development of nano-based technologies for food and agricultural product quality monitoring, identity tracking, and preservation. NEW: Assessment and analysis of perceptions and acceptance of nanotechnology and nano-based products by the general public, agriculture, and food stakeholders using appropriate social science tools. 12

13 Phytoglycogen dendrimer as nano-carrier for antibacterial peptide loading and prolonged release Size of inhibitory ring, mm Advantages as controlled delivery of bioactive compounds essential for the food safety and nutrition and others Surface treated nanoparticle-stabilized emulsion much more effective than emulsions stabilized using modified starch (WCS-OS) or Tween 20 Continuing research (NSF grants) (1) Biotechnology, Biochemical, and Biomass Engineering (BBBE), 01/01/2010 to 12/31/2012, Total fund: $327,603, PI: Yuan Yao, Co-PI: Arun Bhunia. Project title "Designing carbohydrate nanoparticles for prolonged efficacy of bacteriocin against food pathogens" (2) Biomaterials, 07/15/2010 to 06/30/2013. Total fund: $350,000, PI: Yuan Yao, Co-PI: Ganesan Narsimhan, Project title "Dendrimer-like polysaccharides: structure, modification, and functional colloidal assembly" Free nisin PG-OS (DS 0.013) WCS-OS (DS 0.013) Tween Storage time, Day

14 NSF Center Proposal Industry-University Cooperative Research Center (I-UCRC) Brian Cunningham, PI, Illinois Richard Linton, Co-PI, Purdue Irfan Ahmad, Industry Liaison December 7, 2009

15 Over 60 major NNI centers, networks, user facilities Molecular Foundry (Lawrence Berkeley National Laboratory) Cornell NanoScale Science & Technology Facility (CNF) Center for Integrated Nanotechnologies (Sandia & Los Alamos National Labs)

16 NNI Areas of Investment (Program Component Areas)* Fundamental Nanoscale Phenomena and Processes Nanomaterials Nanoscale Devices and Systems Instrumentation Research, Metrology, and Standards for Nanotechnology Nanomanufacturing Major Research Facilities and Instrumentation Acquisition Environment, Health, and Safety (EHS) Education and Societal Dimensions

17 NNI FY 11 Breakout by Program Component Area Fundamental nanoscale phenomena and processes ($484 million) Nanomaterials ($342 million) Nanoscale devices and systems ($402 million) Instrument Research, Metrology and Standards ($77 million) Nanomanufacturing ($101 million) Major research facilities and instrumentation acquisition ($203 million) Environment, Health, and Safety ($117 million) Education and Societal Dimensions ($35 million)

18 Environmental, Health, and Safety (EHS) Budget NNI funding for nanotechnology-related EHS research* has grown much faster than the NNI as a whole. by fiscal year, in $ millions (FY 2010 is estimated, FY 2011 is requested) $ % $120 % growth EHS funding over 2005 $ % % growth total NNI funding over % $100 $87 $92 163% $80 $70 149% 150% $60 $48 100% 100% $40 $35 $38 $20 $0 13% 9% 37% 19% * research whose primary purpose is to understand and address potential risks to health and to the environment from nanotechnology, e.g., not including related instrumentation research 30% 42% 48% 47% % 0%

19 NNI EHS Strategy Development Nanotechnology Environmental and Health Implications (NEHI) Working Group formed as informal body in 2003, formalized in 2005 Extraordinary collaboration between research and regulatory agencies Began with review of respective agencies jurisdictions, responsibilities Industry and non-governmental organizations provided input throughout Environmental, health, and safety research needs published in September 2006: Public meeting held in January 2007 to gather additional input from research community and public Interim document for public comment, Prioritization of Environmental, Health, and Safety Research Needs for Engineered Nanoscale Materials published in August 2007: Nanoscale_Materials.pdf First comprehensive NNI strategy document published in February 2008:

20 NNI EHS Strategy Role of nanotechnology-related EHS research in risk management of nanomaterials* * from Strategy for Nanotechnology-Related Environmental, Health, and Safety Research (February 2008):

21 EPA-NSF-USDA/NIFA Joint Solicitation on EHS Increasing Scientific Data on the Fate, Transport and Behavior of Engineered Nanomaterials in Selected Environmental and Biological Matrices Due: February 2, 2010 Research Area 1: Evaluation of potential exposures to engineered nanomaterials including an exploration of environmental and biological fate, transport, and transformation of these materials throughout their lifetimes Research Area 2: Improve the scientific understanding of engineered nanoscale additives and ingredients that may be intentionally introduced into food for delivery of important micronutrients and modification of sensory attributes.

22 How can industry tap into the NNI? Direct funding via SBIR/STTR programs Some agencies (e.g., DOD, NIH) can fund large company R&D directly also Information on NNI-funded research projects NSF and NIH provide online database of funded projects: will provide comparable information Government-wide NNI-funded user facilities available for use by industry Government as first customer for innovative applications (e.g., National Reconnaissance Office, Navy) Opportunities for industry to participate in NNI research planning workshops; contact NNCO if interested

23 SBIR and STTR funding for nanotechnology Over $390 million in nanotechnology-related Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) funding between 2004 and 2008, inclusive SBI R STTR Tota l SBI R STT R Tota l DOE NSF DHHS/NIH DOD DOC/NIST EPA DHHS/NIOSH NASA USDA/FS USDA/NIFA TOTAL SBI R STT R Tota l SBI R STTR Tota l SBI R STTR Tota l

24 Industry Consultative Boards for Advancing Nanotech Key for development of nanotechnology, EHS coordination Electronic Industry (Semiconductor Research Corporation lead), October/ Collaborative activities in key R&D areas 5 working groups, Periodical joint actions and reports; NSF-SRC agreement for joint funding; other joint funding CCR Chemical Industry (Council for Chemical Research lead) - Joint road map for nanomaterials R&D; Report in 2004; 2 working groups, including one EHS Use of NNI R&D results, and one to identify R&D opportunities Organizations and business (Industrial Research Institute lead) - Joint activities in R&D technology management; 2 working groups (nanotech in industry, EHS) Exchange information, use NNI results, support new topics Forest products industries (AF&PA lead), April 2007 Facilitate forest products industry input to and communication with NSET

25 Education, other societal implications Industry often cites main contribution of the Government is in education and training of the workforce Over $260 million in NNI education and ELSI funding, , not including support for grad. students involved in substantive research Obama Administration initiative, Educate to Innovate : Cooperative effort between industry, government, and non-profit organizations US$260 million in total Includes $100 million from Time Warner Cable to produce shows that promote science and technology Children's favorite Sesame Street will have a two-year focus on science Discovery Communications will deliver science content to 60,000 schools, reaching 35 million pupils Sony will support a challenge to design free, science-based video games National Lab day, Ist week of May 2010 Also involves annual White House Science Fair

26 Nanotechnology in classroom ACS NanoTube Contest - What is "Nano"? Hello, I am Miss Marble, Compared with earth we live on, I am in the Nano size. What is Nano? Nano: 1nm=10^-9m.

27 Effective Public Communication

28 Food Nanotechnology: Understanding the Parameters of Consumer Acceptance Understanding of acceptable characteristics and uses of nanomaterials in food Establish the baseline parameters of acceptability of nanotechnologies in food. (Qualitative interviews) Understand who may be most open to nanotech foods (National survey) Understand factors that influence acceptance (Food sensory experiment) PD: William K. Hallman, Rutgers U.

29 Summary: Recent NNI developments Cumulative NNI funding for nanoscale science and engineering research, : over $14 billion Over 60 NNI research centers, networks and user facilities funded Current NNI Strategic Plan released Dec. 07; due for update 2010 NNI EHS strategy released Feb. 08; also due for update soon Over $480 million in primary purpose EHS R&D, combined; over $260 million in education and ELSI funding over the same period Nanoscale science, engineering and technology for food applications is still in its infancy amply opportunities calls for private-public partnership (PPP) Transparent and proactive public engagement is a key for a successful development and deployment of nanotechnology for the societal and consumer benefits.

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