Rudolf-Zenker-Institut für Experimentelle Chirurgie

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1 30 Rudolf-Zenker-Institut für Experimentelle Chirurgie Rudolf-Zenker-Institut für Experimentelle Chirurgie Universitätsmedizin Rostock Prof. Dr. Brigitte Vollmar Schillingallee 69a Rostock Tel.: +49 (0) Fax: +49 (0) Web: The research topics of the Institute are the analysis of specific pathophysiological processes and the implementation of new therapy concepts to better determine, understand and treat diseases. The main focus lies on the degeneration and regeneration of visceral organs, brain and cardiovascular and musculoskeletal systems. Here socioeconomic relevant widespread diseases, e.g. diabetes, metabolic syndrome and arteriosclerosis, as possible causes and risk factors are paid a particular attention to. Besides the established techniques and methods of basic science, new diverse in-vitro assays and complex experimental animal disease models using genetically manipulated organisms are applied. My expectations of experimental surgery were excelled, although not only positively. Nico Baudis

2 31 Working Group Last name Name School 1 Baudis Nico Erasmus-Gymnasium 2 Baumann Luke Innerstädtisches Gymnasium 3 Gutknecht Tom-Ole Gymnasium Reutershagen 4 Hintze Richard Gymnasium Reutershagen 5 Jung Sabrina Innerstädtisches Gymnasium 6 Kreuzfeld Lennart Innerstädtisches Gymnasium 7 Prus Maxim Erasmus-Gymnasium 8 Screpnecinco Renate Innerstädtisches Gymnasium 9 Walter Lea Innerstädtisches Gymnasium 10 Wendt Lukas ecolea 11 Zenker Lena Gymnasium Reutershagen

3 32 Group work

4 33 Group 4: Augmented human: optimising the human Glasses and protheses have been employed for many centuries to optimise the human body. As of now a new wave of modifying the body is being initiated: by means of the google glasses or a ring that can name objects using a camera. What will the human being look like in 20 years time? Will our skills be extended through implants, drugs or other technical means? Expert: Prof. Dr. Thomas Gerber University of Rostock Moderator: Mr Sidney Berlin Chamber of Industry and Commerce Rostock (IHK) Building: Forschungsbau Physik Room: 2. Obergeschoss, Raum Schülerlabor Visited company: ARTOSS GmbH Prof. Dr. Thomas Gerber Friedrich-Barnewitz-Straße Rostock Tel.: +49 (0) Fax: +49 (0) info@artoss.com Web: Accompanying person: Dr. Jenny Bandomir

5 34 Expert Prof. Dr. Thomas Gerber Faculty MNF/Institute of Physics Prof. Dr. Thomas Gerber is professor for Applied Physics at the University of Rostock and head of the work group nano and biomaterials since Moderation Mr Sidney Berlin Chamber of Industry and Commerce Rostock (IHK)

6 35 ARTOSS GmbH ARTOSS GmbH Prof. Dr. Thomas Gerber Friedrich-Barnewitz-Straße Rostock Tel.: +49 (0) Fax: +49 (0) info@artoss.com Web: Since 2003 Artoss GmbH develops and produces biomaterials for bone regeneration using NanoBone technology, a synthetic bone grafting material. The materials are designed to follow the natural processes occurring in the human body. Originally the research began at the University of Rostock, and still there is an important collaboration between both. Today Artoss cooperates with over 20 universities and is constantly working with users to develop further indication-specific products to facilitate everyday dental and surgical practice. Participants of the European Student Parliament visited the company headquarters in Rostock- Warnemünde, where the NanoBone team develops and produces biomaterials which are sold around the world. I have learned a lot about bone grafting visiting Artoss. It is a topic I didn t know much about before. The company produces synthetic bone grafting materials. The lecture was very challenging, but by all means interesting, since we could gain insight in the production process. Jonas Trappe

7 36 Working Group Last name Name School 1 Bals Ben Christophorus-Gymnasium 2 Berthold Ben-Luca Gymnasium Reutershagen 3 Bolte Lina Gymnasium Reutershagen 4 Ehlert Viktoria Innerstädtisches Gymnasium 5 Gazizova Alina Erasmus-Gymnasium 6 Jaster Natalie Christophorus-Gymnasium 7 Jonas Heinrich ecolea 8 Nguyen Quoc Vinh Erasmus-Gymnasium 9 Philipp Max Christophorus-Gymnasium 10 Philipp Jule Gymnasium Reutershagen 11 Schmidt Johannes Innerstädtisches Gymnasium 12 Steinhäuser Nele Innerstädtisches Gymnasium 13 Trappe Jonas ecolea 14 Voigt Tobias Innerstädtisches Gymnasium

8 37 Group work

9 38 Group 5: Imitating nature Imitating nature through a modular system that is what synthetic biology is about. Scientists hope for new medication and new pharmaceutical ingredients. How is that supposed to function? How can we imitate new biological pieces, gadgets or systems? And don t we overstep the mark here? Expert: Prof. Dr. Olaf Wolkenhauer University of Rostock Moderator: Mr Michael Fengler Spokesman of the County Rostock (Güstrow) Building: Forschungsbau Life, Light & Matter Room: 1. Obergeschoss, Großer Seminarraum Visited company: CELISCA - Center for Life Science Automation Prof. Dr.-Ing. habil. Kerstin Thurow Friedrich-Barnewitz-Straße Rostock Tel.: +49 (0) Fax: +49 (0) Web: Accompanying person: Ms Sonia Cortés Sack

10 39 Expert Prof. Dr. Olaf Wolkenhauer Faculty IEF Dept. of System Biology & Bio Informatics University of Rostock Prof. Dr. Wolkenhauer graduated in engineering at the University of Applied Sciences in Hamburg and at the University of Portsmouth he did his doctorate at UMIST, Manchester, on the application of possibility theory to data analysis. After a research lectureship at the Control Systems Centre at UMIST, and an invited visiting position at the Technical University Delft, Netherlands, he held a joint senior lectureship with the Department of Biomolecular Sciences and the Department of Electrical Engineering and Electronics, at UMIST. Since 2003 he is professor for System Biology and Bio Informatics at the Institute of Computer Science at the University of Rostock. His research focuses on the analysis of data from complex biological and biomedical systems using statistical techniques, mathematical modelling, and computer simulations. Many natural phenomena present themselves as nonlinear, dynamical spatio-temporal systems, producing an amazing variety of behavior and beautiful pattern. To understand how the interactions of molecules and cells can bring about this astonishing structural and functional organization observed in nature is the objective of Prof. Dr. Wolkenhauer s research. He was one of the first engineers in the UK with a joint appointment in the bio-molecular sciences and his current appointment was the first professorship for systems biology in Europe. Through his role in establishing systems biology in Europe, he has been a regular advisor to funding bodies and more recently has helped to define and establish the field of systems medicine through his involvement in the EC FP7 coordination action CaSyM. Moderation Mr Michael Fengler Spokesman of the County Rostock (Güstrow)

11 40 CELISCA Center for Life Science Automation CELISCA - Center for Life Science Automation Prof. Dr.-Ing. habil. Kerstin Thurow Friedrich-Barnewitz-Straße Rostock Tel.: +49 (0) Fax: +49 (0) Web: CELISCA is an international centre of expertise in the field of life science automation. An interdisciplinary team including chemists, biologists, pharmacologists and physicians, as well as electro-technicians, machine builders, computer scientists and automation experts works together to develop new state-of-the-art technologies and on discovering new areas of application. CELISCA s work covers the entire range of life sciences and it orients itself both to the needs of science and to the needs of industry in developing high-end system solutions, special services and forward-looking applications. Since it concentrates, promotes, and combines results and insight from different disciplines, the development of procedures, products and the increase of knowledge are quicker than ever. From its headquarters in Rostock-Warnemünde CELISCA s international research team works closely with research institution all around the world. The visit to Celisca has shown how exciting our future will look like. The innovative, indisciplinary and international research on fundamental current challenges concerining the automation of workplaces in the science field has impressed us a lot.. The robots were cool Wiebke Kuhlmann

12 41 Working Group Last name Name School 1 Basylewicz Christopher Innerstädtisches Gymnasium 2 Dinga Mascha Innerstädtisches Gymnasium 3 Findewirth Lennart Gymnasium Reutershagen 4 Harder Melanie ecolea 5 Kock Max Gymnasium Reutershagen 6 Kuhlmann Wiebke Innerstädtisches Gymnasium 7 Kwiatkowski Leon Innerstädtisches Gymnasium 8 Nguyen Tuan Tung Innerstädtisches Gymnasium 9 Schumacher Lukas Gymnasium Reutershagen 10 Schwarz Lena Innerstädtisches Gymnasium 11 Suleiman Iskander Gymnasium Reutershagen 12 Thrams Florian Innerstädtisches Gymnasium

13 42 Group work

14 43 Parliamentary Debate

15 44 Programme Rathaus der Hansestadt Rostock Bürgerschaftsaal Neuer Markt 1 09:00 09:15 Welcome talk by Mr Holger Matthäus, Senator for Building and Environment, City of Rostock 09:15 09:45 Parliamentary debate: position paper of committee 1 The Human Brain 09:45 10:15 Parliamentary debate: position paper of committee 2 Living and eating healthy but how? 10:15 10:45 Parliamentary debate: position paper of committee 3 Stem cells the potential allrounders? 10:45 11:15 Break 11:15 11:45 Parliamentary debate: position paper of committee 4 Augmented human: optimizing the human 11:45 12:15 Parliamentary debate: position paper of committee 5 Imitating nature 12:15 13:00 Handover of the resolution to the president of the Kuratorium Gesundheitswirtschaft, Prof. Wolfgang Schareck Handover of the certificates to the students 13:00 Closing and departure of the students

16 45 Opening Mr Holger Matthäus, Senator for Building and Environment, greets the participants of the European Student Parliament Rostock in the town hall's Bürgerschaftssaal. The committee is formed (from left to right) by Mr Berlin (Chamber of Commerce and Industry Rostock), Ms Becker (Wissenschaft im Dialog) and the chairman Mr Lüdtke (Agentur H2F). Ms Birgitte Bjørn Petersen from Sønderborg, DK, attends the final debate in order to exchange ideas and experience for their Student Parlament taking place in April 2016.

17 46 Debate Group 1: The Human Brain

18 47 Debate Group 2: Living and eating healthy but how?

19 48 Debate Group 3: Stem cells the potential allrounders?

20 49 Debate Group 4: Augmented human: optimizing the human

21 50 Debate Group 5: Imitating nature

22 51 Resolution

23 52 RESOLUTION OF THE COMMITTEE The Human Brain The human brain has been investigated intensively for years. Experts hope for therapies against dementia illnesses, but also human thinking and feeling is a core focus. But how does our brain work? Can we really simulate our brain and thinking? And will we be able to understand and heal dementia illnesses? proposed by: Erik Bietz (Gymnasium Reutershagen), Anastasia Gaspert (Innerstädtisches Gymnasium), Tobias Kaphengst (ecolea), Lara Nadler (Innerstädtisches Gymnasium), Nick Petschow (Gymnasium Reutershagen), Louise Pischel (Gymnasium Reutershagen), Jette Schmidt (Erasmus-Gymnasium), Tim Schumann (Erasmus-Gymnasium), Fabienne Sperber (Gymnasium Reutershagen), Erik Walter (Erasmus- Gymnasium), Jule Wandrey (ecolea), Dr. Robert Uhde (moderator) We have assessed: 1. The human habits must undergo rapid changes in order to solve important issues such as climate changes, floodings, diseases, epidemics, shortages in food and water. 2. Human brains are the most complex matter in the universe and can resolve these challenges. 3. Latest analysis of brain research indicates, that: I) major milestones have been recently accomplished for the understanding of brain functionality, such as neurons having properties of biological quantum computers and neuron/synaptic plasticity. II) stress is the main factor of importance. III) other areas such as dementia or other diseases are not within the broader mainstream. 4. The most discussed elements in this context are consciousness, the solution for the so called mind and body problem, and methods for stress reduction. 5. We need to build extended mental strength for mind and body, as this is more effective for the accomplishment of our goals.

24 53 6. The existing educational system inhibits this build up process by: I) producing additional stress. II) not sufficiently providing any means of support. 7. Noval educational systems enable us to materialize the future requirements when adapted to the characteristics of consciousness, mind and body (human brain compatible). We claim: 1. New stress reduction methods need to be developed and integrated into our society. (accepted) 2. Novel teaching and learning methods be adapted to current and future state of brain research. (rejected) 3. Measures to change human habits have to be applied in society, that benefit our demanding work and life balance based upon brain research. (rejected) 4. A restructuring of educational systems and the society must be implemented to optimize the mind and body problem as well as utilizing the full brain potential. (rejected) 5. Citizens should be made aware of the fact that a change in their habits is unavoidable for our joint future. (rejected) 6. Brain related science should be introduced into regular classroom education. (accepted) 7. Brain research is receiving highest attention at politics in order to solve all problems as explained above. (rejected)

25 54 RESOLUTION OF THE COMMITTEE Living and eating healthy but how? Organic food is en vogue. But what is that supposed to mean? Do we better not eat meat or even animal products at all? Are genetically engineered foods dangerous for our health? Are long-term consequences to be expected? And how can we be sure what is really healthy and what isn t? proposed by: Michelle Bernitt (Innerstädtisches Gymnasium), Wolfgang Böttcher (Gymnasium Reutershagen), Anna Holz (Christophorus-Gymnasium), Nils Klüber (Gymnasium Reutershagen), Nele Kraatz (Gymnasium Reutershagen), Annika Kutschke (Christophorus-Gymnasium), Paula Lankowski (Innerstädtisches Gymnasium), Carolin Krause (Christophorus-Gymnasium), Anastasia Vatkovich (Innerstädtisches Gymnasium), Henning Vieregg (Christophorus-Gymnasium), Daniel Weidig (Christophorus-Gymnasium), Svenja Wiese (Gymnasium Reutershagen), Lea Zimdahl (Innerstädtisches Gymnasium), Michael Lüdtke (moderator) We have assessed: 1. Alarmed by the frightening number of deaths caused by an unhealthy diet and low physical activity as well as cigarette smoking and environmental influences, 2. Deeply concerned about the current situation in Mecklenburg-Western Pomerania with 59,9 % of overweighed inhabitants, 3. Defining a healthy diet as nutrition that contains five servings of fruits and/or vegetables per day, whole grain foods, low processed foodstuff, enough fiber and trace elements, a reduced intake of sugar and refined polysaccharides and fats, 4. Taking into account that if you have already been diagnosed with a mental and physical health problem, eating well can even help to manage your symptoms and regain control of your life, 5. Noticing that a healthy nutrition contains fruits and vegetables that have a good ecobalance, as a unit of measurement of sustainability, that also has a positive impact on the environment,

26 55 6. In awareness of the action plan of Mecklenburg-Western Pomerania, including stated but not implemented measures, 7. Having noticed higher prices of healthy products, especially organic food, 8. Recognizing that physical activity influences the public health, 9. Underlining the urge to create better healthcare conditions for all individuals regardless of their financial status, 10. Conscious of the fact that individual health is tightly related to the socio-economic status, 11. Emphasizing the lifestyle of a plant-based nutrition, We claim: 1. Calls upon raising awareness and understanding of the needed change of the lifestyle for the human health, environment, challenges for the policy and consequences for the social system; (accepted) 2. Calling for the raise of physical activities with methods such as but not limited to: a) cooperation between several sport clubs, health insurances, schools, kindergartens and companies by: i.) offering a better access to sport centres and clubs with governmental grants, ii.) making physical activity more appealing by offering special rewards for participating in sport courses, iii.) passing on courses that show ways to deal with and to avoid a high stress level, b) fostering physical activities in schools by: i.) creating the possibility to choose the kind of sport, students want to practice, ii.) increasing the amount of PE lessons up to four per week, (rejected) 3. Advises to establish or increase taxes on special kinds of food and luxury foods, especially on: a) fast food, b) products from the intensive livestock farming, c) products, that contain a higher percentage of sugar resulting in a higher daily, recommended intake as defined by the WHO, d) legal drugs like cigarettes and alcohol; (rejected)

27 56 4. Emphasises steps that motivate school to tackle the issue of unhealthy nutrition and low physical activities by: a) including compulsory lessons of nutrition into biology classes, b) offering healthy food and alternatives in cafeterias according to DGE criterions, c) establishing a half of the meals as vegetarian but including fish, d) financially supporting schools to afford one healthy meal for every student, e) suggesting to improve the posture by establish better chairs and tables like heightchangeable desks and stability balls, (accepted) 5. Advises to make organic food more affordable by: a) lowering the prices by using the tax-revenues from unhealthy products, b) governmental subsidies organic companies and farms; (rejected) 6. Stresses to improve and adapt the concepts of fast food chains by: a) appeal the offer in less chemical produced more healthy food, b) build healthy alternative fast food restaurants like healthy snack bars with products such as salad (e.g. shop-in-shop); (rejected) 7. Suggest measures to raise awareness of the deep impact an unhealthy lifestyle has on the human being such as but not limited to: a) campaigns that show the negative aspects of an unhealthy lifestyle, b) cookery courses to make cooking easier and more interesting; (accepted)

28 57 RESOLUTION OF THE COMMITTEE Stem Cells the potential allrounders? There would be no man or any other multicellular creature without stem cells. What are stem cells and why is their investigation this attractive and frowned upon at the same time? How does our life change if we can direct stem cells and how is that supposed to function at all? proposed by: Nico Baudis (Erasmus-Gymnasium), Luke Baumann (Innerstädtisches Gymnasium), Tom-Ole Gutknecht (Gymnasium Reutershagen), Richard Hintze (Gymnasium Reutershagen), Sabrina Jung (Innerstädtisches Gymnasium), Lennart Kreuzfeld (Innerstädtisches Gymnasium), Maxim Prus (Erasmus-Gymnasium), Renate Screpnecinco (Innerstädtisches Gymnasium), Lea Walter (Innerstädtisches Gymnasium), Lukas Wendt (ecolea), Lena Zenker (Gymnasium Reutershagen), Prof. Dr. Udo Kragl (moderator), PD Dr. Hartmut Gläser (moderator), Dr. Catrin Roolf (moderator) We have assessed: 1. Nearly 100% success rate in curing Leukemia with adult stem cells. 2. Lack of information regarding basic functions of stem cells. 3. Stem cells have a huge potential to cure a variety of diseases without currently available treatment. 4. Stem cell therapy and future development bring additional medical risks. Furthermore, miss-use is possible. 5. Research in the field of stem cells will give understanding of aging of cells, but it is expensive. 6. The access to stem cell therapy is unequally distributed over the world. In addition, stem cell and bone marrow donators are rare. 7. Research is restricted by conservative sentiments of society. 8. Research on embryonic stem cells is essential for scientific breakthrough.

29 58 We claim: 1. It is mandatory that everybody is registered as a potential donator for stem cells. (rejected) 2. Allocate more resources to understand the basic functions of stem cells. (accepted) 3. We need qualified personnel and well equipped research facilities along with outreach to the public. (accepted) 4. Independent institutions are needed to control stem cell research and applications. (accepted) 5. We need an international budget allowing less well-stocked countries to participate in this research. (rejected) 6. Cord blood of every new born individual has to be collected and stored preferred separately. (rejected) 7. Scientific progress should overcome cultural and religious barriers. (accepted) 8. We call for a national referendum for the use of embryonic stem cells for research. (rejected)

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