Novo seeds. Changing the world through entrepreneurship. Oslo Cancer Cluster Summer Meeting. Novo SEEDS

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Richard Miles
5 years ago
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1 Novo seeds Changing the world through entrepreneurship Oslo Cancer Cluster Summer Meeting Novo SEEDS

2 Novo Seeds gives budding ideas the chance to develop into unique and life-saving products for the future Could your research lead to better and life-changing treatments in the future?

From research project to a novel life changing treatment Who needs it Unmet need for the product/therapy Is the target novel and scientific rationale promising Superiority over existing solutions

3 From research project to a novel life changing treatment Who needs it Unmet need for the product/therapy Is the target novel and scientific rationale promising Superiority over existing solutions What s the data Quality of research and data Stage of research (test of idea, proof-of-concept) IP, patentability etc. Can it be done Development time and cost, regulatory issues, commercial strategy Plan and budget Team expertise, experiences, network and motivation

4 Novo Seeds is driven by helping researchers transforming amazing research into better and safer treatments Building science Making a plan Taking it to patients

5 How do we help you on the jorney... Exploratory pre-seed grants Pre-seed grants Seed investments Building science Making a plan Taking it to patients Testing of interesting ideas IP analysis Commercial analysis PoC studies Business plan creation Setting the team Lead identification Prototype development Clinical PoC Financial: up to DKK 700,000 up to DKK 3.5 M up to DKK 60 M* Time: up to 12 months up to 18 months to exit 2016 target: * Varies

6 We give more than just the check... We are a partner We can bring advice and network We believe a trustful relationship is important, because a start-up rarely develops as expected You will be in contact with us on a regular basis or during the board meetings We will support you in key decisions

7 Novo Seeds The early-stage Investment arm of NOVO A/S 60bn$ We invest in life science, devices and industrial biotech We focus mainly on Europe We are not a strategic investor for NN

8 YOU plant the seeds. We're here to help them grow! Christina Trojel Diana Muftig NOVO NORDISK FOUNDATION

9 Selected cancer-focused start-ups from our portfolio

10 Never hesitate to reach out.. Novo Seeds receives proposal in ppt, word doc ( / conferences / meetings) Novo Seeds performs high level evaluation of quality, novelty, risk/reward Novo Seeds invites for project presentation if project appear interesting and within scope NOVO NORDISK FOUNDATION Follow up questions, dialogue, meetings Dilligence Phase and decision of pre-seed grant or seed investment

11 Thank you

12 Quick guideline we like to see elements described below.. 1.Good science and quality data: this underpins the application. Data with relevant controls that clearly shows the effect and convinces us that this is an interesting target/moa/molecule/device/diagnostic assay etc 2.Comprehensive presentation: present all relevant data to tell the story. Everyone at Novo Seeds has a scientific background and convincing data is a large part of a good application 3.Don t: Please don t send a list of publications expecting us to read through it and find the most important facts. Sell your story actively! 4.Do: send a few pivotal articles that validate your findings, e.g show that the target is validated 5.Background: give a background to the indication/area but focus on how your data is unique in the setting and how it addresses something novel. It is preferential if the team has a knowledge of where the scientific community as well as the commercial pipeline is in regards to the indication and can articulate how their approach is unique 6.Differentiation and uniqueness: what differentiates your invention to existing treatments as well as most obvious competing products in development. How does your product address the medical need in a way that no other product does and in what exact patient population does it do so. Consider outlining a Target Product Profile 7.Market/IP/Other analysis: if there is a previous analysis done please include it in the presentation, but a general overview (eg. Cancer kills many people or ) has low value-add 8.Team: briefly present the team and relevant credentials 9.Plan going forward: A plan showing what the next steps are, including scientific activities, collaborations etc and what the pre-seed grant would be used for. This can always be a point of discussion and collaboration if the grant is approved but we would like to see that team is in the driving seat

13 Examples of Novo Seeds portfolio companies Discovery Lead Optimisation Pre-clinical Clinical Phase I Clinical Phase II Acesion Pharma Atrial fibrillation Small molecules Pcovery Anti-fungal Forendo Pharma Endometriosis Galecto Fibrosis Inthera Oncology Glionova Glioblastoma RSPR Pharma Allergic asthma Proteins peptides Affinicon Macrophage targeted drugs Avilex Neuroprotection Adenium Anti-microbial IO Biotech Immuno-oncology MinervaX GBS vaccine Lysogene Gene therapy PoC Prototype Development PMA/510k Sales MedTech Reapplix Wound care Denator Protein stabilization Bio-industrial Discovery / feasibility Biosyntia Vitamins by fermentation Process development Pilot scale Commercial scale

SciLifeLab Drug Discovery Workshop Uppsala 1 June Nanna Lüneborg Novo Seeds

SciLifeLab Drug Discovery Workshop Uppsala 1 June 2015 Nanna Lüneborg Novo Seeds Novo Seeds Seed arm of Novo A/S European seed investor with Scandinavian focus Building companies through grants and investments