Global DNA Sequencing Market Report

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Global DNA Sequencing Market Report ----------------------------------------- 215

Executive Summary DNA sequencing market is one of the fastest growing segments of the life sciences tools market. This research study includes the market assessment of various products, technologies, applications and end-users. The report briefs about the classification in genomics, process of transcription and translation of DNA, historical development, and generations of sequencing technologies. The sequencing industry is majorly classified into 3 generations; first generation, second generation / next generation and emerging sequencing technologies. Next-gen sequencing has been the fastest to grow since 21. The core factors generating demand and driving the growth of industry are growth of emerging and applied economies, heavy investments in research and development, rapid rise in complex diseases, rising infertility at young ages and many more. The emerging technologies are on the way of growth, thus reducing the cost of DNA sequencing. Some of the noteworthy trends and developments include growing demand from healthcare, declining sequencing cost and recent mergers and acquisitions. However, the industry growth is hindered by front and back-end challenges like faster changes in technology, emerging competition, rising complexity of diseases, and rising R&D cost. The report analyzes the global DNA sequencing market along with an extensive coverage of its major product segments. The sequencing industry witnesses intense competition with numerous top notch players; such as Illumina Inc., Roche and Thermo Fisher; operating in the marketplace along with small budding players like Pacific Biosciences. The fierce competition prevailing in the sequencing industry has been studied on a number of parameters such as emerging market exposure, R&D expenditures, and presence in various market segments. The company profiles of leading players in the market are also presented in the report. By combining SPSS Inc. s data integration and analysis capabilities with our relevant findings, we have predicted the future growth of the industry. We employed various significant variables that have an impact on this industry and created regression models with SPSS Base to determine the future direction of the industry. Before deploying the regression model, the relationship between several independent or predictor variables and the dependent variable was analyzed using standard SPSS output, including charts, tables and tests.

A AFFX BDX BIM-FR BRKR CPHD CRL FLDM GHDX GNMK HOLX ICEL ILMN LMNX MTD MYGN NEOG NSPH OXFD OSUR PKI QDEL QGEN ROKA TMO VCYT VIVO VWR WAT US$ Million Life science tools are the instruments and consumables used in areas such as basic research, genetic analysis, and biopharmaceutical discovery, development, and production. Global Market Value by Life Science Tools (214) 1 8 6 4 2 The US$... billion Life Science Tools market has been a consistent GDP-plus grower for years. Geographically, almost half of Life Science Tools aggregate revenues are generated in the United States, about. from Europe, and.% from the rest of the world, predominantly in the rapidly growing Asia Pacific region. One of the major end markets targeted by the Life Science Tools group is the Industrial & Applied end market (~.% of weighted Tools sales). Agilent (.%), VWR (~ %), Bruker (~ %), Waters (~.%), PKI (~..%), ROKA ( %), and NEOG (..%) all have high exposure to the Industrial & Applied end market as a percentage of sales. Global Life Science Tools End Market Mix by Company (214) Global Life Science Tools Market Share by Geography (214) 1% 9% 8% US 7% 6% 5% 29% 4% 3% 2% 1% % Others 6% Healthcare Ind / App BioPharma ACA / GOVT

Sequencing is defined as determining the linear order of bases in a segment of DNA. By analyzing the order of bases, variations that are specific to an organism or group of individuals can be used to correlate or associate these variations with certain attributes. % US$ Million % Global DNA Sequencing Market Size and YoY Growth (29-217E) 6 5 4 3 2 1 29 21 211 212 213 214E Market Size YOY Growth 14 12 1 8 6 4 2 In 213, global DNA sequencing market size realized US$... billion, up 6% year on year. It is predicted that in 214, global DNA sequencing market size will increase by.% on YoY basis to US$... billion. By product, global DNA sequencing market consisted of instruments & consumables, service and workflow products. The former occupied % of market share in 213, but was estimated to decline to..% in 217. DNA sequencing target market has great potential, hitting US$... billion at least and applications include oncology, reproduction and genetic diseases, microbiology, agricultural genomics and other fields, in which oncology can reach US$... billion. Global DNA Sequencing Market by Type (214) Global DNA Sequencing Market Potential by Uses (214) 1 7 9 8 7 6 5 4 3 2 1 213 217E Instruments and Consumables Service Workflow Oncology Other 1.9

Technological improvements continue to rapidly drive down the cost of generating sequence data while expanded system menus and lower system price points are enabling market expansion First Gen Sub Segment Sales by End Market Mix (214) Clinical Academic The market for CE Sequencing can be divided into 4 segments. The largest sub segment happens to be clinical and human identification with sales share of approximately % each. The rest is shared by academic uses as well as biopharma by.% and.% respectively. Nucleic acid testing currently include whole genome analysis, DNA seq, RNA seq, and re-sequencing, and other forms of structural analysis. These applications have utility in various areas including academic research (.%), applied markets & diagnostics (.%), and AgBio (.%). The product mix is equally shared by consumables/services and instruments by revenue share of approximately.% of sales. Where Instruments contribute approximately US$...million, contribution by annuity is limited to US$...million. Next Gen Sub Segment Sales by End Market Mix (214) Next Gen Sub Segment Sales by Product Mix (214) Academic / Government ASP/ Instrument Consumable s / Services Instrumenta tion Annuity Stream