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Media Planner 2018 www.themedicinemaker.com

medicines Why choose APRIL 2017 # 29 Substance Upfront How to catch cargo criminals In My View Why are we still waiting for biosimilars? Sitting Down With Ace MHRA assessor, Daniel O Connor 10 18 50 51 Style Power List 2017 Meet the Top 100 most inspirational professionals shaping the future of drug development. 22 48 www.themedicinemaker.com We love great design We insist on excellence We embrace a challenge Understanding that a scientific mind is also a creative mind, we put a great deal of energy into creating content that inspires as well as informs. Whether in digital (adaptive design), print (quality paper, perfect bound), video (cuttingedge technology), or webinars (robust platforms), we strive for top quality and collaborate with field-leading partners. Our ever-evolving portfolio is driven by a highly experienced and forward-thinking team. Why? To provide you with the perfect environment to influence your target customers at their most open minded. Why? To ensure that the quality of your company and value of your brands is reflected through our entire portfolio. Why? To offer you tailored marketing campaigns that match any goal or budget, but always with unrivaled service and support. We craft content to offer an immersive experience We own your customer s day By delving into the motivations, challenges and aspirations of key figures in the field, we help form a deeper connection with our audience and build solid loyalty. Whether a quick coffee-break catch-up or a deep dive into emerging trends, an abundance of varied content across multiple platforms hooks our audience into regular engagement. Why? To give your message the best possible chance of being remembered. Why? To give your message the best possible chance of being seen. We cater for all professionals working in Life Sciences Our highly accessible content attracts readers at all stages of their career and crosses traditional application-based boundaries. Why? To give you access to over 86,000 professionals in diverse markets that span the full range of purchasing power from consumables to complete systems to entire labs.

Audience and Market The Medicine Maker targets professionals responsible for the development and commercial realisation of new medicines, including small molecules, biopharmaceuticals, and advanced therapies. Who Are Our Readers? 60 50 40 30 20 10 0 51% Pharma/biopharma company CMO/CDMO 20% Drug Development Services 9% CRO 7% Clinical Trial Organisation 4% Regulatory Research/Insitution/Foundation Data/Information Specialist 3% 2.5% 2% Academia 1% Employed By Other 0.5% DIGITAL REA DERS 60,150 The Medicine Maker Geographical Reach PRINT REA DERS 26,500 25 20 15 10 5 0 25% R&D 15% Manufacuring/ Engineering 14% Process Development Management/Corporate 9% Materials Development Laboratory and Analytical Services 8% 8% Regulatory Affairs 7% QA/QC, Validation 6% Primary Job Function Clinical Affairs Data Services Other 3.5% 3.5% 1% Digital Print Field of Work 6% 3,609 37% 22,256 Europe ROW US 57% 34,285 Europe US 50% 13,250 50% 13,250 20 15 10 5 0 18% Contract Services; Development/Manufacture 18% Biologic/Biopharmaceutical Development 16% 16% Pharmaceutical Manufacturing Biologic/Biopharmaceutical Manufacturing 15% Pharmaceutical Development Clinical Trials 7% Discovery Research Regulatory Affairs 4% 4% Marketing and Communication 1.5% Other 0.5%

Marketing Planner Regular Topics Key Features and Supplements Bonus Distribution January Packaging, Drug Delivery, Future of Pharma Manufacture ACHEMA Special: The Medicine Maker of Tomorrow Part 1 Pharmapack Europe 2018 07 February 2018-08 February 2018 Pittcon 26 February 2018-01 March 2018 February Track and Trace, Analytical Technology, Product Release ACHEMA Special: The Medicine Maker of Tomorrow Part 2 Bio Europe Spring 12 March 2018-14 March 2018 Making Pharmaceuticals Europe 13 March 2018-14 March 2018 DCAT 19 March 2018-22 March 2018 PDA Europe Annual Meeting 19 March 2018-21 March 2018 CPHI South East Asia 27 March 2018-29 March 2018 March Formulation, Packaging, Supply Chain ACHEMA Special: The Medicine Maker of Tomorrow Part 3 Analytica 10 April 2018-13 April 2018 Interphex 17 April 2018-19 April 2018 CPHI Japan 18 April 2018-20 April 2018 RDD 22 April 2018-26 April 2018 CPhI NA 24 April 2018-26 April 2018 CPHI Russia 24 April 2018-26 April 2018 Making Pharmaceuticals 24 April 2018-25 April 2018 April Solid Dosage, Vaccines, Continuous Processing The Power List The top 100 professionals in drug development & manufacture ISCT 2018 02 May 2018-05 May 2018 World Biosimilar Congress USA 23 May 2018-24 May 2018 May Automation, Facilities, Bioprocessing BIO International Conference 04 June 2018-07 June 2018 ACHEMA 11 June 2018-15 June 2018 Chemspec Europe 2018 20 June 2018-21 June 2018 CPHI China 20 June 2018-22 June 2018 DIA 24 June 2018-28 June 2018 June Drug Delivery, Formulation, Biosimilars Controlled Release Society 22 July 2018-24 July 2018 July Small Molecule Manufacture, Process Analytical Technology, Corporate Social Responsibility Advanced Medicines Examining the challenges of cell and gene therapies CPHI Korea 28 August 2018-30 August 2018 August Track & Trace, Packaging, Continuous Processing Analytical Advances / Bioanalytics Charting the advances in analytical and bioanalytical technology BPI Conference and Expo 04 September 2018-07 September 2018 September Ingredients, Supply Chain, Formulation CPhI WW 09 October 2018-11 October 2018 October November Outsourcing, Facilities, Bioprocessing Bioprocessing, Formulation, Second Hand Equipment AAPS 04 November 2018-08 November 2018 Lab Innovations (Date TBC) Pharma Integrates (Date TBC) December Advanced Medicines, Supply Chain, Ingredients Innovation Awards Top equipment released during 2018 Calendar is subject to change

Product Portfolio Webinars Educational series Audio with slides Increased audience participation Virtual round table discussion Video webinar Digital Channels Distribution channel Ebooks Multimedia channel Content Development Educational features Interview article Opinion blogs Customer testimonials Magazine Display advertising Loose or bound inserts Application notes Targeted supplements Wall planners Video Production Product demonstration Customer testimonials Conference/Expo interviews Thought leadership Email Products Electronic direct mail Whitepaper e-alerts Weekly e-newsletters Monthly content round up Website Banner adverts White papers Product profiles Content promotion Video hosting Lead nurturing Market Intelligence/Surveys 5-10 question basic survey Detailed smart logic survey Detailed survey with full report and leads

Meet Our Customers Ingredients For a company to feel they are making the right choice when choosing a media partner, it is important to know they are in good hands. To celebrate our fourth year we would like to thank all of the following companies who have helped make The Medicine Maker to become what it is today. We also hope this will provide new companies with the confidence that The Medicine Maker could help with their marketing needs. Contract Development Manufacturing Organisation Analytical Instrumentation/Services Pharmaceutical Manufacturing/Packaging Equipment Bioprocessing/Bioproduction Drug Delivery

Rates Summary Technical Specifications Magazine Adverts 1x 3x 6x 9x Full Page 5,065 4,913 4,761 4,609 2/3 Page 4,407 4,274 4,142 4,010 1/2 Page 3,900 3,783 3,666 3,549 1/3 Page 2,938 2,850 2,761 2,673 1/4 Page 2,533 2,457 2,381 2,305 Collaborative Content and Sponsored Features Collaborative Content (1 page feature) 7,195 Collaborative Content (2 page feature) 12,510 Newsletters Preferred Positions Outside Back Cover 810 Inside Front Cover 650 First Right Hand Page 675 Preferred Position 475 Belly Band 6,600 Cover Tip 6,600 Newsletters 1 Issue 3 Issues 6 Issues Product Profiles 860 774 731 Leaderboard 995 896 846 Footer Banner 780 702 663 Road Block 4,587 4,420 4,253 Other Market Intelligence Surveys 5 Questions 6,400 10 Questions 8,000 15 Questions 10,400 20 Questions 12,800 25 Questions 16,000 Ebook / Supplement Ebook Supplement POA POA Webinars Audio with Slides - Live or Pre-recorded 10,500 Video Webinar POA Online Video Production Customer Testimonial Product Introduction Exhibition Booth Interviews Video Application Notes POA Website Position Size Monthly Rate 1 Year Content Filter 900 x 210 2,850 27,360 Article Sidebar 300 x 200 2,365 22,700 Homepage Skyscraper 200 x 600 2,365 22,700 Content Hub Call for details 2,850 27,360 Eblasts Global Audience eblast 6,095 Targeted eblast 225 per '000 Magazine Ad Sizes Metric Imperial Page Unit Width x Depth Width x Depth Full Page 210mm x 266mm 8.3 x 10.5 2/3 Page 130mm x 266mm 5.1 x 10.5 1/2 Horizontal 210mm x 130mm 8.3 x 5.1 1/2 Vertical 100mm x 266mm 3.9 x 10.5 1/3 Vertical 70mm x 266mm 2.75 x 10.5 1/3 Square 130mm x 130mm 5.1 x 5.1 1/4 Page 100mm x 130mm 3.9 x 5.1 1/6 Page 70mm x 130mm 2.75 x 5.1 Format: All files must be supplied as PDF. Please ensure all fonts are embedded, and that all images used within are CMYK and at least 300dpi in quality. Bleed: Please supply with 3mm bleed on all sides. Live area: All text must be inset at least 5mm on all external edges. On internal edges (i.e. right hand side on a left hand page advert), we recommend insetting text by at least 10mm, to compensate for any space lost when binding. e-newsletter Formats and sizes: All images below to be provided as JPG, PNG or GIF file types, with a maximum size of 45KB. All sizes in pixels. Banners Leaderboard Banner 728 x 90 Footer Banner 728 x 90 Product Profile - Text: Headline - up to 12 words. Body text - up to 45 words describing the product. Image: 150 x 150 image - image of product. Hyperlink. Whitepaper - Text: Headline - up to 12 words. Body text - up to 45 words describing the application note. Image: 150 x 150 image - image of application note content. Exhibitor Highlight - Headline - up to 12 words. Body text up to 45 words describing the event. Image: 150 x 150 Logo. Hyperlink. Website Ad Sizes Right Hand Column Box Small Skyscraper Large Skyscraper Metric Width x Depth 200 x 200px 200 x 300px 200 x 500px In Content Postcard 300 x 200px Content Filter 3 sizes for different browser 450 x 210px window sizes 540 x 210px 900 x 210px Formats and sizes: All ads to be provided as JPG, PNG, GIF file types, with a maximum size of 45KB. White paper (Print) Your company name Title: up to 12 words Subtitle: 10-20 words Body Text: Max 450 words (reduce by 75 words for additional image) Author(s) (no company affiliations) Abstract: a description of what the Application Note contains; two or three sentences maximum Email Address: for leads Contact name Contact phone number Logo: supplied in high resolution format (300dpi, CMYK) as JPG, PDF, TIF or Illustrator file Images: any associated diagram image that you may feel is appropriate URL Link: one address that will link from the page Any additional online content supplied in PDF format

Publisher: Richard Hodson richard.hodson@texerepublishing.com Editor: Stephanie Sutton stephanie.sutton@texerepublishing.com Sales Manager: Helen Conyngham helen.conyngham@texerepublishing.com Content Director: Rich Whitworth rich.whitworth@texerepublishing.com Editorial Director: Fedra Pavlou fedra.pavlou@texerepublishing.com Production: Jody Fryett jody.fryett@texerepublishing.com Multimedia: Lindsey Vickers lindsey.vickers@texerepublishing.com Tel UK: +44 (0) 1565 745 200 Tel US: +1 646 712 9435 info@texerepublishing.com www.texerepublishing.com