Advanced Immunoassay Testing

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Symmetry in Diagnostics FULLY AUTOMATED ENZYME IMMUNOASSAY ANALYZER Advanced Immunoassay Testing TOSOH BIOSCIENCE www.tosohbioscience.us

High Powered and Flexible Immunoassay Testing Throughput of 200 results per hour Load up to 960 tests (48 trays) Automatic inventory management of reagents and supplies Additional substrate bottle prevents depletion Automated daily maintenance and record keeping Random access and continuous loading Dual sampling arms User defined programming True auto dilution from 2 to 1000 Unit Dose Test Cup reagent system

Time Tested Reliable Reagents: Tosoh Unit Dose Test Cup Dry reagent format requires no pre-mixing, no premeasuring, no on board refrigeration and no waste. Calibration stability of up to 90 days for most assays. Reagents have one year shelf life from date of manufacture. Bar-coded for automated scheduling and inventory management. Extensive test menu includes thyroid, cardiac markers, tumor markers, reproductive hormones, anemia markers, and metabollic assays. Reagent Diagram Common to all Tosoh AIA Platforms Report with Confidence Sophisticated calibration and control monitoring. Customizable flags. Graphical depiction of results. All AIA instruments provide consistent results between testing platforms. Tosoh s technical team of experts ensures accurate result reporting. QC Result Print-out

Time is of the Essence Throughput of 200 tests per hour. First result in approx. 18 minutes. Minimal maintenance: Daily maintenance takes approx. 5 minutes. Multiple robotic arms and 3 incubators, handle the various sample processing steps quicker to speed up overall sample processing. Continuous processing allows specimens, tips and reagents to be added without interrupting work in progress. Multiple STAT processing available. Freedom to Walk Away 960 test cups give a walk away time of approx. 5 hours. AIA-2000 Operation: Simple and Intuitive Touch screen monitor allows easy instrument operation. Simple icons and color codes guide the operator. User friendly software runs on Windows Vista platform. Automated daily maintenance. Automated pre-treatment. Automated dilution. Reflex testing. Customizable pop-up reminders for reagent inventory and calibration curve stability. 576 tips give a walk away time of approx. 3 hours. 2 substrate bottles give a walk away time of approx. 4 hours. 16 positions for secondary reagents. 20 sample racks (200 specimens) can be loaded at one time. Ask about Line Automation Model.

200 Sample Loader 4 Wash Probes Secondary Reagents 576 Pipette Tips 960 Test Cups Touch Sreen Monitor

Main Specifications Assay principal Processing method Processing capacity In vitro diagnostic reagent Sample volumes Sample clot detection Measuring conditions Specimen dilution factors Specimen pretreatment Detection method Precision control Reagent Sorter Reagent set count Fluorometric enzyme immunoassay (FEIA) Automated continuous random access Max. 200 tests/h. (ST reagents) AIA-PACK Series 10 to 125 ul Pressure detection Reaction temperature: 37 degrees Celsius Antigen-antibody reaction time: 10 min., 20 min. or 40 min. (depending on assay specification) 2 per assay specification selectable in the 2 to 1000 range Automatic pretreatment (10 min. at 37 degrees Celsius) Fluorescent measurement (top-to-top system) Multirule (Levey-Jenning s charts) Max. 48 trays (equivalent to 48 analytes or 960 tests) Can be added or changed at any time by key request Tip Sorter Tip Dedicated tips Tip set count 576 (96/rack, in 6 racks) Can be added or changed at any time by key request Sample Loader Specimen set count 200 specimens, (add/change as required) STAT: Using the Priority rack Sample containers Test tubes :13x75, 13x100, 16x75, 16x100 mm (Diameter x Length) Can be used in combination with dedicated sample cups Specimen barcodes CODE39, CODE128, ITF, NW-7,JAN compatible (compliant with ASTM14466-92 and CLA guideline compliant barcodes) Min. element width: 0.191mm (0.254mm or over recommended) Reagent Carousel Reagent set count Holds a max. of 16 reagent types Can be added or changed at any time by key request External Input/Output RS-232C (ASTM) or Ethernet (HL7 V2.4) Power Supply/Power Consumption AC 100-240 V, 50/60 Hz 700 VA (excluding controller PC and printer (option)) Over voltage category II External Dimensions/Weight (excluding controller PC and monitor) AIA-2000 ST 1500(W) x 907(D) x 1260(H) mm / 400 kg 59.1(W) x 35.7(D) x 49.6(H) inches / 881.8 lb AIA-2000 LA 1500(W) x 1197(D) x 1260(H) mm / 400 kg 59.1(W) x 47.1(D) x 49.6(H) inches / 881.8 lb Operating Environment Temperature 15 to 30 degrees Celsius Humidity 40% to 80% R.H. (with no condensation) Pollution degree 2 Dust Average office level Altitude Up to 2000 m Conformity Standard EMC standard IEC61326-1: 2005 / EN61326-1: 2006, IEC61326-2-6: 2005 / EN61326-2-6: 2006 CISPR class and group categories Class A, Group 1 FCC Part 15, Sub Part B, Class A Barcode Reader Class 1: IEC60825-1: 2001 TOSOH BIOSCIENCE AIA-PACK and AIA are the registered trademarks of Tosoh Corporation in United States, Canada, etc. Tosoh Bioscience, Inc. 6000 Shoreline Court, Suite 101 South San Francisco, CA 94080 Tel: (800) 248-6764 Fax: (650) 615-0415 www.tosohbioscience.us Part # 0095-20-0913