COURSE NUMBER: EH 540 SECTION NUMBER: 000 SEMESTER: Fall 2016

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DEPARTMENT: Environmental Health COURSE NUMBER: EH 540 SECTION NUMBER: 000 SEMESTER: Fall 2016 CREDIT HOURS: 2 Credits COURSE TITLE: EH540 Environmental Hazards I. INSTRUCTOR NAME P. Barry Ryan INSTRUCTOR CONTACT INFORMATION EMAIL: bryan@emory.edu PHONE: 404.727.3826 SCHOOL ADDRESS OR MAILBOX LOCATION: CNR Rm 2041 MS 1518-002-2BB OFFICE HOURS By Appointment, Contact by email and set up appointment. TAs re your first contact. Teaching Assistants: Molly Steele (molly.steele@emory.edu) Office hours: Monday 4-5pm CNR 2015 Claire Mattison (claire.mattison@emory.edu) Office Hours: Thursday 3-4 pm Thursdays. BRIEF COURSE DESCRIPTION Integrates aspects of environmental science, environmental management, and industrial hygiene through exploration of the underlying principles common to both environmental and occupations hazard evaluation. Students will be exposed to units on environmental and industrial contamination, health and safety, and the interface between the industrial environment and the community environment. Class structure will include lecture materials, a special-topics paper, and classroom discussion. EH 540 is a required course for all EH, GEH, and both EH/EPI and BS/MPH Dual Degree students. LIST SCHOOL LEVEL, DEPARTMENT, AND/ OR PROGRAM COMPETENCIES Upon completion of the EH540, the student will be able to: Describe major environmental risks to human health ranging from the local to global scale Assess the sources and movement of contaminants through the environment Characterize the magnitude, frequency and duration of environmental exposures Evaluate the risks posed by environmental hazards using risk assessment methods (Partial)

LIST LEARNING OBJECTIVES ASSOCIATED WITH THE COMPETENCIES 1. To familiarize students with the basic analytical methods of environmental and occupational health. 2. To introduce concepts of environmental science, environmental hygiene, and industrial hygiene in a quantitative fashion. 3. To have students begin to synthesize these concepts through thorough analysis of selected environmental problems. Students will be introduced to the basic material of environmental and occupational health through a series of lectures focusing on concepts in environmental and industrial hygiene and basic environmental science. 1. The course will develop basic competencies necessary for continued work in Environmental Health 2. All classes subsequent to this one will assume that the material covered in this course has been mastered. 3. A unique feature of the course will be the integration of aspects of environmental science, environmental hygiene, and industrial hygiene. EVALUATION Homework Sets: Note: Homework sets have different numbers of total points, but each counts 12% of the grade. If you get 80/160, it is the same as getting 45/90 for the purposes of this grading. Note the due dates for each homework are general on Fridays with the exception of Thanksgiving week when they are due on Tuesday. Answers will be posted at 5PM the Monday following the due date. No homeworks will be accepted after the answers are posted. Homework Set #1: 12% Homework Set #2: 12% Homework Set #3: 12% Homework Set #4: 12% Homework Set #5: 12% Homework Set #6: 12% Mid-term Quiz- 14% End-of-term Quiz or Paper 14% Challenge Questions 1 point on final grade each If you choose to do a five-page paper, the topic must be cleared with the Instructor by October 28. Failure to do so will result in a default to the end-of-term quiz. ACADEMIC HONOR CODE The RSPH requires that all material submitted by a student in fulfilling his or her academic course of study must be the original work of the student.

Syllabus for the Class There are readings associated with each class session. The required readings can be found on BlackBoard. Supplemental readings are available for checkout outside Dr. Ryan s office, CNR 2041. Week #1 30 August 2016 SESSION #1 ADMINISTRATIVE (15 MINUTES) We will discuss course expectations, requirements, and grading criteria. SESSION #2 ATMOSPHERE- GAS LAWS AND GENERAL CIRCULATION OF THE ATMOSPHERE, This lecture will cover aspects of the atmosphere important for understanding the impact on environmental health. Topics covered will include the composition of the atmosphere, including trace gas concentrations and the atmosphere as an ideal gas Readings (found on Blackboard) Week #1 and Week #2 The Atmosphere. P. Barry Ryan. Elementary Thermodynamics. P. Barry Ryan An Interesting Website: http://ocw.usu.edu/forest range and_wildlife_sciences/wildland_fire_m anagement_and_planning/unit_7 atmospheric_stability_and_instability_ 1.html Some basic ideas. Chapter 1 in The Physics of Atmospheres. Third Edition. John Houghton. Cambridge University Press. Cambridge, UK. 2002. The Atmospheric Circulation: Transporter of Chemical Constituents. Chapter 4 in Atmospheric Change. An Earth System Perspective. TE Graedel and PJ Crutzen. WH Freeman and Company. New York. 1993. Chapters 3, 8, 9-14 in Atmospheric Change. An Earth System Perspective. TE Graedel and PJ Crutzen. WH Freeman and Company. New York. 1993. These chapters are quite readable and will give a good background in atmospheric and water chemistry and physics. Chapter 1-3 in Atmosphere, Weather & Climate. RG Barry and RJ Chorley. Rutledge. London and New York. 1998. An alternative presentation to the Greadel and Crutzen presentations in your packet. Approximately the same level. Chapters 2-4. The Physics of Atmospheres. Third Edition. John Houghton. Cambridge University Press. Cambridge, UK. 2002. This is advanced material and requires some mathematical sophistication. Week #2 6 September 2016- Pressure and Temperature Structure of the Atmosphere

This lecture will focus on the pressure structure and the temperature structure of the atmosphere and how it affects atmospheric stability and results in different effects in different parts of the atmosphere Homework #1 Problem Solving Due Friday 9 September 2016 at 5PM in EH540 BlackBoard Submission Area. Help sessions to be held during the weeks of August 29 and September 5. Week #3 13 September 2016. GLOBAL ENERGY BALANCE AND GLOBAL CLIMATE CHANGE Another topic receiving interest in the popular press and in the scientific community is the so-called Greenhouse Effect. In this lecture, we will discuss the global balance of energy of the planet and the role trace gases in the atmosphere have on temperature near the surface. We will discuss the impact of changing the concentrations of these trace gases, which ones are important and which ones are not. We will discuss the effects of continued increase in certain trace gases with regard to inhabited areas of the planet. Readings (On BlackBoard): Atmospheric Energy Balance. P. Barry Ryan Chapter 6: In Chemistry of the Environment. Thomas G. Spiro and William M. Stigliani. 2 nd Edition. Prentice Hall, Englewood Cliffs, New Jersey. 2003. Week #4 20 September 2016 SESSION #1: ATMOSPHERIC POLLUTION EFFECTS AND HEALTH: STRATOSPHERIC AND TROPOSPHERIC CHEMISTRY. The hole in the ozone layer is current topic of news and scientific interest. The causes behind the phenomenon, the persistence of the problem, and potential cures will be the topic of this lecture. We will explore the physics of the stratosphere and the chemistry of ozone to discover why this problem occurs and persists. We will discuss its biological impact and measures being instituted to control the problem. In contrast to stratospheric ozone where less is bad, in the troposphere, the presence of ozone is a problem. We will discuss the physics and chemistry of the lower troposphere to discover how the problem arises initially. We will spend time examining control strategies and discuss the effects of such strategies alone and in concert with one another. Finally, we will look briefly at the indoor environment and examine the special problems of concern there. Readings (On BlackBoard): Notes on Stratospheric and Tropospheric Chemistry. SESSION #2: AIR POLLUTION CHEMISTRY.

We will focus on the polluted urban atmosphere discussion smog formation, aerosol formation, sources, mechanisms, and natural clean-up processes. This discussion will be in preparation for addressing modeling of pollution transport. Readings (On BlackBoard): Notes on Atmospheric Chemistry. Chapters 2, 3, and 4: In Chemistry of the Environment. Thomas G. Spiro and William M. Stigliani. 2 nd Edition. Prentice Hall, Englewood Cliffs, New Jersey. 2003 SESSION #3: AIR POLLUTION AND HEALTH. Homework #2 The Atmosphere. Due Friday 23 September 2016 at 5PM in EH540 BlackBoard Submission Area Week #5 27 September 2016 Energy Production. This session will focus on the production of energy in the United States through coal, natural gas, hydro, and nuclear systems. The principal aim will be to evaluate the pollution produced given the energy produced. A cradle-to-grave identification of the system will be evaluated. What contamination of the environment occurs during mining, refining, use, and waste streams from each of these? Readings (Found on BlackBoard): Energy Production. P. Barry Ryan Week #6 4 October 2016 THE BASIC HYDROLOGICAL CYCLE SESSION #1- IN CLASS MID-TERM QUIZ Material to be covered includes all lectures through Energy Production SESSION #2: THE BASIC HYDROLOGICAL CYCLE. Cycling of water on the Earth, ocean-atmosphere heat coupling El Nino, weather, and acidic deposition. Readings (found on Blackboard) The Hydrological Cycle. P. Barry Ryan The Water Cycle and Climate. Chapter 6 in Atmospheric Change. An Earth System Perspective. TE Graedel and PJ Crutzen. WH Freeman and Company. New York. 1993. Week #7 11 October 2016 Fall Break NO CLASS

Homework #3 Atmospheric Chemistry and Energy Production Due Friday 14 October 2016 at 5PM in EH540 BlackBoard Submission Area Week #8 18 October 2016 2016 MOVEMENT OF WATER IN THE ENVIRONMENT SESSION #1: DISCUSSION OF GROUNDWATER AQUIFERS, THEIR CONTAMINATION Confined and unconfined aquifers, surficial and artesian well systems, groundwater movement, and Darcy s Law and its relationship to soil makeup and permeability as it affects pollutant movement through the environment. Week #9 25 October INTRODUCTION TO WATER AND SANITATION SESSION #1: THE DEVELOPED WORLD SESSION #2: THE DEVELOPING WORLD In these two sessions we will follow a parallel development geared towards understanding the topics of clean water delivery and water sanitation. We will first explore the developed world with a discussion of modern water purification and wastewater treatment plants. We will then spend time discussing the developing world with the needs and particular challenges found in regions for Readings (found on Blackboard) The Hydrological Cycle P. Barry Ryan Optional Paper Topic due by this class. Homework #4. Groundwater Movement and Introduction to Water and Sanitation. Due Friday 28 October 2016 at 5PM in EH540 CNR BlackBoard Submission Area. Week #10 1 November 2016 VISIT TO EMORY (WATER HUB) Emory has a unique water recovery system in place that allows the use of gray water, processed through a phytoremediation system and then used for certain activities such as water plants and toilet flushing. We will divide into two groups with each group being given a tour of the facilities. Details will be forthcoming. Week #11 8 November 2016 THE INDUSTRIAL HYGIENE PARADIGM- ANTICIPATION, RECOGNITION, EVALUATION, AND CONTROL. This lecture will present the Anticipation, Recognition, Evaluation and Control paradigm for evaluation of environmental health and safety in the occupational environment. Readings (Found on BlackBoard) generally Applicable for Weeks 8-13: Chapter 4. Exposure Assessment, Industrial Hygiene and Environmental Management. P. Barry Ryan.

The Industrial Hygiene Survey and Personnel. James O. Pierce. Chapter 4 in Patty s Industrial Hygiene and Toxicology. George D Clayton and Florence E. Clayton. Eds. Fourth Edition, Volume I, Part A. General Principles. John Wiley & Sons, Inc. New York. 1991. Selected Readings from: Potential Exposures in the Manufacturing Industry- Their Recognition and Control. William A. Burgess. Chapter 18 in Patty s Industrial Hygiene and Toxicology. George D Clayton and Florence E. Clayton. Eds. Fourth Edition, Volume I, Part A. General Principles. John Wiley & Sons, Inc. New York. 1991. Chapter 5 (The Role of the Industrial Hygiene Consultant), 15 (Quality Control),16 (Calibration), Remainder of Chapter 18, 21 (Heat Stress), 22 (Air Pollution Controls), 23 (Noise), in Patty s Industrial Hygiene and Toxicology. George D Clayton and Florence E. Clayton. Eds. Fourth Edition, Volume I, Part A. General Principles. John Wiley & Sons, Inc. New York. 1991. Chapter 27 (Sampling), 28 (Engineering Controls), 29 (Air Pollution), 35 (Loss Prevention), 38 (Ionizing Radiation), 39 (Non-Ionizing Radiation), and 40 (Ergonomics) in Patty s Industrial Hygiene and Toxicology. George D Clayton and Florence E. Clayton. Eds. Fourth Edition, Volume I, Part B. General Principles. John Wiley & Sons, Inc. New York. 1991 Week #11 15 November 2016 INTRODUCTION TO BIOMARKERS Biomarkers are commonly used in both occupational and environmental settings to quantify the exposure experienced by individuals. In this lecture, we will explore the utility of biomarkers and discuss some specific examples in common use. Readings (Found on BlackBoard): Ryan PB, Burke TA, Cohen Hubal EA, Cura JJ, and McKone TE. Using Biomarkers to Inform Cumulative Risk Assessment. Environ Health Perspect EHP 115(5) 833-840 (2007) doi:10.1289/ehp.9334 available via http://dx.doi.org/ [Online 24 January 2007] Other readings will be developed and selected over the course of the semester. Homework #5. Industrial Hygiene and Biomarkers. Due Friday 18 November 2016 at 5PM in EH540 BlackBoard Submission Area Week #12 22 November 2016 SESSION #1: ELEMENTS OF ENVIRONMENTAL MODELING.

This session will focus on compartmental ( box ) models and their application tom, various environmental systems. Concepts covered include sources, sinks, and lifetime in environmental compartments. The session will end with a brief overview of alternative applications of compartmental models including pharmacokinetics. SESSION #2: COMPARTMENTAL MODELING- EXAMPLES. This session will focus on applications of compartmental modeling. The session will include a computer laboratory session in which simple compartmental models of environmental systems will be developed. These will be drawn from important problems such as indoor air quality, industrial ventilation, and contaminated ponds. SESSION #3: MULTI-COMPARTMENT MODELING If time allows, we will extend our discussion of compartmental modeling to multi-compartment systems. We will examine two-compartment systems first, followed by more complex, and useful, systems. The second half of the class will be devoted to solving such systems using MSExcel. Readings (found on Blackboard) Compartmental Modeling in Environmental Health P. Barry Ryan. Chapter II. Tools of the Trade Part A. Steady-State Box Models and Residence Times. Parts 7-11, Pages 40-64 in Consider a Spherical Cow. A Course in Environmental Problem Solving. J Harte. University Science Books. Mill Valley, California. 1988. More examples of varying complexity. This entire book is written at a very accessible level and is an excellent introduction to ways of addressing environmental modeling. Homework #6 Environmental Modeling. Due Friday 2 December 2016 at 5PM in EH540 BlackBoard Submission Area Week #14 29 November 2016 OVERVIEW OF SPECIFIC ENVIRONMENTAL AND OCCUPATIONAL HAZARDS I In the final two classes, we will discuss specific environmental hazards as outlined here. Readings will be developed and selected over the course of the semester. Focus on Neurological and Neurodevelopmental Effects SESSION #1: METALS EFFECTS SESSION #2: PESTICIDES Week #15 6 December 2016 OVERVIEW OF SPECIFIC ENVIRONMENTAL AND OCCUPATIONAL HAZARDS II Focus on Radiation and Air Pollution Effects SESSION #1: RADIATION (KANSTANTIN KARTAVENKA, 4 TH YEAR PHD STUDENT)

SESSION #2: COMMUNITY AIR POLLUTANTS Week #17 Take Home Exam Due Wednesday 14 December 2016 at 5PM in EH540 CNR Second-Floor Mailbox Material to be covered includes all material through Week #13, Environmental Modeling. The lecture material from Weeks #14 and #15, are general and will not be quizzed. Not that the optional paper done in lieu of the Take-Home Exam will be Due Wednesday 14 December 2016 at 5PM in EH540 CNR Second-Floor Mailbox