1 Quiz1 Q1 2011 Alpha-helices, beta-sheets and U-turns within a protein are stabilized by (hint: two words) Value Correct Answer 1 noncovalent interactions 100% Equals hydrogen bonds (100%) Equals H-bonds (100%) Equals H bonds (100%) Equals hydrogen bond (100%) Equals hydrogen bonds (100%) Equals H-bond (100%) Equals noncovalent bonds (100%) Equals hydrogen-bond (100%) Equals H-bonding (100%) 2 Quiz1 Q2 2011 If a double-stranded DNA molecule is 200-bp (bp = base pairs) in length and has a total of 125 C's then how many T's does it have? (hint: give only a number) Value Correct Answer 1 75 100% Equals 75 (100%) Equals seventy five (100%) Equals seventy-five (100%) 3 Quiz1 Q3 2011
Which of the following is not normally found in DNA? 1 phosphodiester bonds 2 deoxyribose 3 thymine 4 uracil 5 two of the above 4 Quiz1 Q4 2011 Which of the following is encoded by genes? 1 polypeptides 2 trnas 3 rrnas 4 ribozymes 5 all of the above 5 Quiz1 Q5 2011 Which of the following bases is not normally found in mrna? 1 uracil 2 adenine 3 inosine 4 guanine 5 two of the above
6 Quiz1 Q6 2011 Which of the following is consistent with the general characteristics of polypeptides and RNA? 1 both are polymers 2 both have end bias (eg, the ends are not the same) 3 both can form secondary structures 4 both can have enzymatic activity 5 all of the above 7 Quiz1 Q7 2011 A zinc-finger motif is often found in 1 DNA- or RNA-binding proteins 2 Calcium-binding proteins 3 Fibrous proteins 4 trna 5 non of the above 8 Quiz1 Q8 2011 Which of the following cannot form a wobble base-pair with inosine? 1 C
2 G 3 U 4 A 5 two of the above 9 Quiz1 Q9 2011 Z-DNA 1 can form from short DNA molecules of alternating A's and G's 2 forms a left handed helix 3 is single-stranded 4 is not found in living cells 5 two of the above 1 0 Quiz1 Q10 2011 What are the three basic "ingredients" for RNA polymerization? a DNA template b rntps c dntps d RNA polymerase e primer 1 a, c, e 2 a, d, e 3 a, c, d 4 a, b, e 5 a, b, d
1 Question 1 A typical human cell contains approximately 32 billion base pairs of DNA If you could stretch this DNA out as a single fibre of B form DNA, the length of the fibre would be closest to A 100 meters B 10 meters C 1 meter 100% D 1 cm 2 Question 2 The 3 dimensional structure of a protein reveals a 5 amino acid alpha-helical region buried in the interior of the protein, ie in the region of the protein that does not interact with the solvent Which amino acids would most likely be found in this helical region? A Thr, Ser, Lys, His, Arg B Glu, His, Asp, Gly, Gln C Leu, Val, Ile, Phe, Ala 100% D Cys, Pro, Val, Arg, Glu 3 Question 3 Which of the statements below best explain why DNA and not RNA serves at the carrier of hereditary information?
A DNA contains thymidine and RNA does not B The base uracil, which is found in RNA, is unstable C Only DNA contains phosphodiester bonds D Due to the presence of the 2 OH group on the sugar ribose, RNA strands are more susceptible to hydrolytic cleavage 100% 4 Question 4 The coiled-coil structural motif is stabilized primarily by A H-bonds between the amino acids of the two coils B Binding of Ca++ ions C Binding of Zn ions D Hydrophobic interactions between the 100%
amino acids of the two coils 5 Question 5 The sequence with which the various aspects of transcription initiation sites occur on the template DNA strand, when read in the 5 to 3 direction, are: A Initiation site, promoter, coding sequence B Promoter, initiation site coding sequence C Coding sequence, promoter, initiation site D Coding sequence, initiation site, promoter 100% 6 Question 6 The first three nucleotides of an RNA molecule, when read in the 5 to 3 direction, are G, C and U What will be the sequence, in the 5 to 3 direction, that codes for these three nucleotides on the template DNA strand? A G,C, T B A, G, C 100%
C C, G, A D None of answers a, b or c are correct 7 Question 7 Which of the following DNA sequences would most likely be present as a Z-DNA double helix? A 5 GGGGGGGG 3 B 5 GCGCGCGC 3 100% C 5 ATATATATAT 3 D 5 AAAAAAAA 3 8 Question 8 In prokaryotes, the number of transcription initiation sites is always equal to the number of translation start sites Value Correct Answer False 100% False 9 Question 9 We discussed three forms in which double stranded DNA can exist, B, A and Z In which of these forms are the bases positioned most closely to one another?
Value Correct Answer 1 A 100% Contains A (100%) Contains Z (100%) 2 not answered 0% Contains A (100%) Contains Z (100%) 1 0 Question 10 Regions of DNA that are required for the initiation of transcription are termed 1----- Value Correct Answer 1 promoters 100% Equals promoters (100%) Equals promoter (100%) Equals promoter sequences (100%) Equals promoter regions (100%) Equals promoter sequence (100%) Equals promoter region (100%)