Cambridge Healthtech Institute

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1 Cambridge Healthtech Institute Your Life Science Network Conference & Course Catalog September 2016 February 2017 CHI is a division of Cambridge Innovation Institute RESEARCH COLLABORATION ADVANCEMENT

2 TABLE OF CONTENTS CONFERENCE SERIES Biological Therapeutic Products... 4 Biomarkers and Diagnostics... 4 Bioprocess and Manufacturing... 5 Clinical Trials & Translational Medicine... 6 Chemistry... 6 BioPharmaceutical Strategy... 6 Drug Discovery & Development... 7 Drug Targets... 7 Genomics... 8 Healthcare... 8 Informatics and IT... 9 Therapeutic Indications... 9 Technology and Tools for Life Sciences...10 CONFERENCES BY DATE WITH DETAIL SHORT COURSE SCHEDULE About Cambridge Healthtech Institute For over 20 years, Cambridge Healthtech Institute has developed more than 800 conferences, which have attracted over 60,000 attendees from around the world. CHI is the industry leader in offering quality programs that provide valuable new insights and competing points of view while offering balanced coverage of the latest developments in the life science industry. Leading researchers and business experts from top pharmaceutical, biotech, and academic organizations present their most current findings in a forum that features panel discussions and audience participation. Each year, CHI organizes over 170 annual events geared to the biotech and pharmaceutical industries with specific focuses on Biomarkers, Genomics, Proteins and Proteomics, Drug Discovery & Development, IT and Informatics, Chemistry, Diagnostics & Safety, and Business. For a comprehensive listing and detailed information about our products and services, please visit: healthtech.com. Follow youtube.com/user/cambridgehealthtech CONTACT US CUSTOMER SERVICE Pamela Gerardi Director of Customer Service E: pgerardi@healthech.com T: Kris Waterman Sr. Customer Service Representative E: kwaterman@healthtech.com T: Rose LaRaia Customer Service Representative E: rlaraia@healthtech.com T: MARKETING Jim MacNeil Vice President of Marketing E: jmacneil@healthtech.com T: Rich Handy Senior Director of Marketing E: rhandy@healthtech.com T: SPONSOR & EXHIBIT SALES Angela Parsons Vice President of Business Development E: aparsons@healthtech.com T: Carol Dinerstein Director, Business Development E: dinerstein@healthtech.com T: GROUP SALES David Cunningham Director, Inside Sales E: cunningham@healthtech.com T: GRAPHICS Thomas Norton Design Director E: tnorton@healthtech.com T: PRODUCTION Edel O Regan, Ph.D. Vice President of Production E: eoregan@healthtech.com T: Christina Lingham Executive Director of Conferences E: clingham@healthtech.com T: Mary Ann Brown Executive Director of Conferences E: mabrown@healthtech.com T: Julia Boguslavsky Executive Director of Conferences E: juliab@healthtech.com T: Micah Lieberman Executive Director of Conferences E: mlieberman@healthtech.com T: linkedin.com/company/cambridge-healthtech-institute Cambridge Healthtech Institute 250 First Avenue, Suite 300 Needham, MA T: (781) or Toll-free in the U.S F: (781) Cambridge Healthtech Institute

3 2016 KEY EVENTS September 19-22, 2016 Westin Boston Waterfront Boston, MA DiscoveryonTarget.com EUROPE The Essential Protein Engineering Summit October 31-November 4, 2016 EPIC SANA Lisboa Hotel Lisbon, Portugal PEGSummitEurope.com 2017 KEY EVENTS January 9-13, 2017 Hilton San Diego Bayfront San Diego, CA CHI-PepTalk.com Summit for Clinical Trials Ops Executives January 24-26, 2017 Hyatt Regency Miami Miami, FL SCOPESummit.com February 19-24, 2017 Moscone North Convention Center San Francisco, CA TriConference.com April 24-26, 2017 Sheraton San Diego Hotel & Marina San Diego, CA DrugDiscoveryChemistry.com PEGSummit.com BOSTON The Essential Protein Engineering Summit May 1-5, 2017 Seaport World Trade Center Boston, MA May 2-4, 2017 Marriott Philadelphia Downtown Philadelphia, PA BiomarkerWorldCongress.com May 23-25, 2017 Seaport World Trade Center Boston, MA Bio-ITWorldExpo.com June 13-15, 2017 Westin Copley Place Boston, MA WorldPreclinicalCongress.com LIFE SCIENCE MEDIA LIBRARY Continue Your Education with CHI s Digital Courses Navigate, pause, rewind and listen to recorded sessions in a multimedia presentation. Visit CHI s Life Science Media Library to view over 120 digital courses recorded at our most successful events. Formats available: Digital Download On Demand DVD Order Today Healthtech.com/MediaLibrary September 2016 February

4 Conferences by Series Biological Therapeutic Products The Immuno-Oncology Summit August 29 - Sept. 2, 2016 Boston, MA Adoptive T Cell Therapy Biomarkers for Immuno-Oncology Clinical Trials for Cancer Immunotherapy NK Cell-Based Cancer Immunotherapy Antibodies Against Membrane Protein Targets - Part 1 Targeting Cardio-Metabolic Diseases GPCR-Based Drug Discovery - Part 2 Antibodies Against Membrane Protein Targets - Part 2 PEGS Korea September 20-22, 2016 Seoul, Korea Engineering for Novel Biotherapeutics September 20-22, 2016 Seoul, Korea Cancer Immunotherapy September 20-22, 2016 Seoul, Korea Immunogenicity & Bioassay Summit October 26-28, 2016 Baltimore, MD Immunogenicity Assessment & Clinical Relevance October 26-27, 2016 Baltimore, MD Immunogenicity Prediction and Control October 27-28, 2016 Baltimore, MD Optimizing Bioassays for Biologics October 27-28, 2016 Baltimore, MD PEGS Europe Oct Nov. 4, 2016 Lisbon, Portugal Novel Immunotherapy Strategies Optimisation & Developability Display of Antibodies Engineering Next-Generation Antibody- Drug Conjugates Advancing Bispecifics and Combination Therapy to the Clinic Optimising Expression Platforms Analytical Characterisation of Biotherapeutics Engineering Antibodies Engineering Bispecifics Novel Therapies for Cancer and Emerging Targets Protein Aggregates & Particles Protein Purification Technologies Preclinical Models for Cancer Immunotherapy and Combinations November 14-15, 2016 Lisbon, Portugal Antibacterial Discovery December 7-8, 2016 Boston, MA DNA- and RNA-Based Vaccines December 6, 2016 Boston, MA ImVacS - Immunization and Vaccine Summit December 7-9, 2016 Boston, MA Advances in Vaccine Technologies December 7-8, 2016 Boston, MA Vaccine Adjuvants December 8-9, 2016 Boston, MA PepTalk-The Protein Science Week January 9-13, 2017 San Diego, CA Optimizing Biologics Formulation Development Engineering Next-Generation Cancer Immunotherapies Recombinant Protein Therapeutics Characterization of Biotherapeutics Single-Use Technologies and Continuous Processing Protein Purification and Recovery Antibody-Drug Conjugates Recombinant Protein Expression and Production Enhancing Antibody Binding and Specificity Detection and Characterization of Particulates and Impurities Extractables and Leachables January 11-12, 2017 San Diego, CA Higher-Throughput Protein Production and Characterization Protein Aggregation and Emerging Analytical Tools Bispecific Antibody Therapeutics Optimizing Expression Platforms Emerging Technologies for Antibody Discovery Bioprocess Analytics Molecular Med Tri-Con February 19-24, 2017 San Francisco, CA Translational Models in Oncology and Immuno-Oncology Biomarkers for Cancer Immunotherapy 4 Cambridge Healthtech Institute

5 Conferences by Series The Immuno-Oncology Summit August 29 - Sept. 2, 2016 Boston, MA Clinical Trials for Cancer Immunotherapy Leaders in BioBanking Congress September 7-9, 2016 Baltimore, MD Targeting Ocular Disorders Targeting the Microbiome - Part 2 Immunogenicity Assessment & Clinical Relevance October 26-27, 2016 Baltimore, MD Preclinical Models for Cancer Immunotherapy and Combinations November 14-15, 2016 Lisbon, Portugal Advances in Prenatal Diagnostics Nov Dec. 1, 2016 Cambridge, MA Reproductive Genetic Diagnostics December 1-2, 2016 Cambridge, MA Antibacterial Discovery December 7-8 Boston, MA Engineering Next-Generation Cancer Immunotherapies Managing Precision Medicine Trials Sample, Lab and Diagnostic Services in Clinical Trials Molecular Medicine Tri-Con February 19-24, 2017 San Francisco, CA PCR & NGS-Based Molecular Diagnostics Genomic Sample Prep, Biomarker Assay Development and Validation Digital Pathology Molecular Diagnostics Molecular Diagnostics for Infectious Disease Personalized Diagnostics Cancer Molecular Markers Circulating Tumor Cells and Liquid Biopsy Translational Models in Oncology and Immuno-Oncology Clinical NGS Diagnostics Circulating Cell-Free DNA Microbiome-Based Precision Medicine Point-of-Care Diagnostics Genomic Knowledge Bases, Annotation and Interpretation Biomarkers for Cancer Immunotherapy Commercialization of Molecular Diagnostics Oncolytic Virus Immunotherapy August 29-30, 2016 Boston, MA Immunogenicity Prediction and Control October 27-28, 2016 Baltimore, MD Optimizing Bioassays for Biologics October 27-28, 2016 Baltimore, MD Optimising Expression Platforms Protein Purification Technologies PepTalk - The Protein Science Week January 9-13, 2017 San Diego, CA Optimizing Biologics Formulation Development Recombinant Protein Therapeutics Engineering Genes and Hosts Characterization of Biotherapeutics Single-Use Technologies and Continuous Processing Lyophilization and Emerging Drying Technologies Protein Purification and Recovery Antibody-Drug Conjugates Recombinant Protein Expression and Production Detection and Characterization of Particulates and Impurities Extractables and Leachables January 11-12, 2017 San Diego, CA Higher-Throughput Protein Production and Characterization Protein Aggregation and Emerging Analytical Tools Bispecific Antibody Therapeutics Optimizing Expression Platforms Emerging Technologies for Antibody Discovery Bioprocess Analytics Microbial Production September 2016 February

6 Conferences by Series Adoptive T Cell Therapy Clinical Trials for Cancer Immunotherapy Leaders in BioBanking Congress September 7-9, 2016 Baltimore, MD Strategies for Tackling Rare Genetic Diseases Autoimmunity - Small Molecule Approaches GPCR-Based Drug Discovery - Part 1 Gene Therapy Breakthroughs Targeting Cardio-Metabolic Diseases Translating Cancer Genomics GPCR-Based Drug Discovery - Part 2 Metabolomics in Drug Discovery Immunogenicity & Bioassay Summit October 26-28, 2016 Baltimore, MD Immunogenicity Assessment & Clinical Relevance October 26-27, 2016 Baltimore, MD Immunogenicity Prediction and Control October 27-28, 2016 Baltimore, MD Optimizing Bioassays for Biologics October 27-28, 2016 Baltimore, MD Novel Immunotherapy Strategies Advancing Bispecifics and Combination Therapy to the Clinic Strategic Resource Management November 2-3, 2016 Philadelphia, PA Portfolio Management November 3-4, 2016 Philadelphia, PA Re-Entering Antibacterial Discovery and Development Summit December 7-9, 2016 Boston, MA Antibacterial Development and Market Access December 8-9, 2016 Boston, MA Summit for Clinical Ops Executives (SCOPE) January 24-26, 2017 Miami, FL Clinical Data Strategy and Analytics Protocol Development, Global Site Selection, Feasibility and Site Management Managing Late Stage Research and Observational Studies Enrollment Planning and Patient Recruitment Clinical Trial Forecasting and Budgeting Implementing Risk-Based Monitoring- Part 1 Establishing an Outsourcing Strategy Managing Precision Medicine Trials Clinical Technology and Innovation Managing Outsourced Clinical Trials Implementing Risk-Based Monitoring- Part 2 Improving Site-Study Activation and Performance Patient Engagement, Enrollment and Retention through Communities and Technology Leveraging Real World Data for Clinical and Observational Research Sample, Lab and Diagnostic Services in Clinical Trials Genomic Sample Prep, Biomarker Assay Development and Validation February 20-22, 2017 Translational Models in Oncology and Immuno-Oncology February 20-22, 2017 Discovery on Target September 19-22, 2016 Boston, MA Strategies for Tackling Rare Genetic Diseases Autoimmunity - Small Molecule Approaches Targeting the Ubiquitin Proteasome System GPCR-Based Drug Discovery - Part 1 Targeting Histone Methyltransferases and Demethylases Targeting Cardio-Metabolic Diseases Kinase Inhibitor Discovery GPCR-Based Drug Discovery - Part 2 Targeting Epigenetic Readers and Chromatin Remodelers Metabolomics in Drug Discovery World Preclinical Congress - Europe November 14-16, 2016 Lisbon, Portugal Mastering Medicinal Chemistry November 14-15, 2016 Lisbon, Portugal Optimizing Leads and Predicting Drug Toxicity November 15-16, 2016 Lisbon, Portugal Antibacterial Discovery December 7-8, 2016 Boston, MA Biocatalysis and Bio-Based Chemical Production 6 Cambridge Healthtech Institute

7 Conferences by Series Strategic Resource Management November 2-3, 2016 Philadelphia, PA Portfolio Management November 3-4, 2016 Philadelphia, PA Summit for Clinical Ops Executives (SCOPE) January 24-26, 2017 Miami, FL Commercialization of Molecular Diagnostics The Immuno-Oncology Summit August 29 - Sept. 2, 2016 Boston, MA Adoptive T Cell Therapy Biomarkers for Immuno-Oncology Clinical Trials for Cancer Immunotherapy Discovery on Target September 19-22, 2016 Boston, MA Next-Generation Histone Deacetylase Inhibitors Strategies for Tackling Rare Genetic Diseases Understanding CRISPR: Mechanisms and Applications NK Cell-Based Cancer Immunotherapy Autoimmunity - Small Molecule Approaches Targeting the Microbiome - Part 1 Targeting the Ubiquitin Proteasome System Silencing - Part 1 GPCR-Based Drug Discovery - Part 1 Targeting Histone Methyltransferases and Demethylases Antibodies Against Membrane Protein Targets - Part 1 Gene Therapy Breakthroughs Targeting Ocular Disorders Targeting Cardio-Metabolic Diseases Kinase Inhibitor Discovery Translating Cancer Genomics Silencing - Part 2 GPCR-Based Drug Discovery - Part 2 Targeting Epigenetic Readers and Chromatin Remodelers Antibodies Against Membrane Protein Targets - Part 2 Targeting the Microbiome - Part 2 Metabolomics in Drug Discovery PEGS Korea September 20-22, 2016 Seoul, South Korea Immunogenicity Assessment & Clinical Relevance October 26-27, 2016 Baltimore, MD Immunogenicity Prediction and Control October 27-28, 2016 Baltimore, MD Optimizing Bioassays for Biologics October 27-28, 2016 Baltimore, MD Optimisation & Developability Display of Antibodies Advancing Bispecifics and Combination Therapy to the Clinic Engineering Antibodies Engineering Bispecifics Novel Therapies for Cancer and Emerging Targets High-Content Analysis & 3D Screening Oct Nov. 3, 2016 Cambridge, MA 3D Cell Culture: Organoid, Spheroid, and Organ-on-a-Chip Models Oct Nov. 1, 2016 Cambridge, MA High-Content Analysis Oct Nov. 1, 2016 Cambridge, MA Phenotypic Screening November 1-2, 2016 Cambridge, MA Screening and Functional Analysis of 3D Models November 1-2, 2016 Cambridge, MA World Preclinical Congress - Europe November 14-16, 2016 Lisbon, Portugal Mastering Medicinal Chemistry November 14-15, 2016 Lisbon, Portugal Preclinical Models for Cancer Immunotherapy and Combinations November 14-15, 2016 Lisbon, Portugal Optimizing Leads and Predicting Drug Toxicity November 15-16, 2016 Lisbon, Portugal Use of CRISPR & RNAi for Drug Discovery November 15-16, 2016 Lisbon, Portugal Re-Entering Antibacterial Discovery and Development Summit December 7-9, 2016 Boston, MA ImVacS-Immunization and Vaccine Summit December 7-9, 2016 Boston, MA Engineering Next-Generation Cancer Immunotherapies Enhancing Antibody Binding and Specificity Emerging Technologies for Antibody Discovery Bioprocess Analytics Translational Models in Oncology and Immuno-Oncology New Frontiers in CRISPR-Based Gene Editing Microbiome-Based Precision Medicine September 2016 February

8 Conferences by Series Drug Targets SERIES The Immuno-Oncology Summit August 29 - Sept. 2, 2016 Boston, MA Adoptive T Cell Therapy Biomarkers for Immuno-Oncology Clinical Trials for Cancer Immunotherapy Leaders in BioBanking Congress September 7-9, 2016 Baltimore, MD Discovery on Target September 19-22, 2016 Boston, MA Next-Generation Histone Deacetylase Inhibitors Strategies for Tackling Rare Genetic Diseases Understanding CRISPR: Mechanisms and Applications NK Cell-Based Cancer Immunotherapy Autoimmunity - Small Molecule Approaches Targeting the Microbiome - Part 1 Targeting the Ubiquitin Proteasome System Silencing - Part 1 GPCR-Based Drug Discovery - Part 1 Targeting Histone Methyltransferases and Demethylases Antibodies Against Membrane Protein Targets - Part 1 Gene Therapy Breakthroughs Targeting Ocular Disorders Targeting Cardio-Metabolic Diseases Kinase Inhibitor Discovery Translating Cancer Genomics Silencing - Part 2 GPCR-Based Drug Discovery - Part 2 Targeting Epigenetic Readers and Chromatin Remodelers Antibodies Against Membrane Protein Targets - Part 2 Targeting the Microbiome - Part 2 Metabolomics in Drug Discovery Engineering for Novel Biotherapeutics September 20-21, 2016 Seoul, Korea Cancer Immunotherapy September 21-22, 2016 Seoul, Korea Novel Immunotherapy Strategies Optimisation & Developability Advancing Bispecifics and Combination Therapy to the Clinic Engineering Antibodies Engineering Bispecifics Novel Therapies for Cancer and Emerging Targets 3D Cell Culture: Organoid, Spheroid, and Organ-on-a-Chip Models October 31 - November 1, 2016 Cambridge, MA Phenotypic Screening November 1-2, 2016 Cambridge, MA Screening and Functional Analysis of 3D Models November 1-2, 2016 Cambridge, MA Use of CRISPR & RNAi for Drug Discovery November 15-16, 2016 Lisbon, Portugal Re-Entering Antibacterial Discovery and Development Summit December 7-9, 2016 Boston, MA Engineering Next-Generation Cancer Immunotherapies Enhancing Antibody Binding and Specificity Emerging Technologies for Antibody Discovery New Frontiers in CRISPR-based Gene Editing Next-Generation Histone Deacetylase Inhibitors Understanding CRISPR: Mechanisms and Applications Targeting the Ubiquitin Proteasome System Silencing - Part 1 8 Cambridge Healthtech Institute Targeting Histone Methyltransferases and Demethylases Gene Therapy Breakthroughs Kinase Inhibitor Discovery Translating Cancer Genomics Silencing - Part 2 Targeting Epigenetic Readers and Chromatin Remodelers World Preclinical Congress - Europe November 14-16, 2016 Lisbon, Portugal Preclinical Models for Cancer Immunotherapy and Combinations November 14-15, 2016 Lisbon, Portugal Use of CRISPR & RNAi for Drug Discovery November 15-16, 2016 Lisbon, Portugal Plant-Based Expression and Synthetic Biology

9 Managing Precision Medicine Trials Sample, Lab and Diagnostic Services in Clinical Trials Molecular Medicine Tri-Con February 19-24, 2017 San Francisco, CA PCR & NGS-Based Molecular Diagnostics Genomic Sample Prep, Biomarker Assay Development and Validation February 20-22, 2017 San Francisco, CA Digital Pathology Bioinformatics for Big Data Molecular Diagnostics Molecular Diagnostics for Infectious Disease Personalized Diagnostics Cancer Molecular Markers Conferences by Series Translational Models in Oncology and Immuno-Oncology Clinical NGS Diagnostics New Frontiers in CRISPR-Based Gene Editing Circulating Cell-Free DNA Genomic Knowledge Bases, Annotation and Interpretation Reproductive Genetic Diagnostics December 1-2, 2016 Cambridge, MA Antibacterial Development and Market Access December 8-9, 2016 Boston, MA Managing Late Stage Research and Observational Studies Patient Engagement, Enrollment and Retention through Communities and Technology Leveraging Real World Data for Clinical and Observational Research Translational Models in Oncology and Immuno-Oncology Digital Pathology Converged IT Summit October 24-26, 2016 San Diego, CA Bioprocess Analytics Summit for Clinical Ops Executives (SCOPE) January 24-26, 2017 Miami, FL Clinical Data Strategy and Analytics Clinical Technology and Innovation Molecular Med Tri-Con February 19-24, 2017 San Francisco, CA Integrated Pharma Informatics Bioinformatics for Big Data Genomic Knowledge Bases, Annotation and Interpretation SERIES The Immuno-Oncology Summit August 29 - Sept. 2, 2016 Boston, MA Adoptive T Cell Therapy Biomarkers for Immuno-Oncology Clinical Trials for Cancer Immunotherapy Discovery on Target September 19-22, 2016 Boston, MA Next-Generation Histone Deacetylase Inhibitors Understanding CRISPR: Mechanisms and Applications Autoimmunity - Small Molecule Approaches Targeting the Microbiome - Part 1 Targeting the Ubiquitin Proteasome System Silencing - Part 1 Targeting Histone Methyltransferases and Demethylases Gene Therapy Breakthroughs Targeting Ocular Disorders Targeting Cardio-Metabolic Diseases Kinase Inhibitor Discovery Translating Cancer Genomics Silencing - Part 2 GPCR-Based Drug Discovery - Part 2 Targeting Epigenetic Readers and Chromatin Remodelers Targeting the Microbiome - Part 2 Metabolomics in Drug Discovery September 2016 February

10 Conferences by Series PEGS Korea September 20-22, 2016 Seoul, Korea Novel Immunotherapy Strategies Optimisation & Developability Advancing Bispecifics and Combination Therapy to the Clinic Engineering Antibodies Engineering Bispecifics Novel Therapies for Cancer and Emerging Targets Re-Entering Antibacterial Discovery and Development Summit December 7-9, 2016 Boston, MA Antibacterial Discovery December 7-8, 2016 Boston, MA Antibacterial Development and Market Access December 8-9, 2016 Boston, MA Engineering Next-Generation Cancer Immunotherapies New Frontiers in CRISPR-based Gene Editing Microbiome-Based Precision Medicine Biomarkers for Cancer Immunotherapy Adoptive T Cell Therapy Leaders in BioBanking Congress September 7-9, 2016 Baltimore, MD Discovery on Target September 19-22, 2016 Boston, MA Next-Generation Histone Deacetylase Inhibitors Strategies for Tackling Rare Genetic Diseases Understanding CRISPR: Mechanisms and Applications NK Cell-Based Cancer Immunotherapy Targeting the Ubiquitin Proteasome System Silencing - Part 1 GPCR-Based Drug Discovery - Part 1 Targeting Histone Methyltransferases and Demethylases Antibodies Against Membrane Protein Targets - Part 1 Gene Therapy Breakthroughs Kinase Inhibitor Discovery Translating Cancer Genomics Silencing - Part 2 GPCR-Based Drug Discovery - Part 2 Targeting Epigenetic Readers and Chromatin Remodelers Antibodies Against Membrane Protein Targets - Part 2 Metabolomics in Drug Discovery Converged IT Summit October 24-26, 2016 San Diego, CA Novel Immunotherapy Strategies October 31 - November 1, 2016 Lisbon, Portugal Optimisation & Developability October 31 - November 1, 2016 Lisbon, Portugal Advancing Bispecifics and Combination Therapy to the Clinic Optimising Expression Platforms Analytical Characterisation of Biotherapeutics Engineering Antibodies Engineering Bispecifics Protein Aggregates & Particles November 3-4, 2016 Lisbon High-Content Analysis & 3D Screening Oct Nov. 3, 2016 Cambridge, MA 3D Cell Culture: Organoid, Spheroid, and Organ-on-a-Chip Models Oct Nov. 1, 2016 Cambridge, MA High-Content Analysis Oct Nov. 1, 2016 Cambridge, MA Phenotypic Screening November 1-2, 2016 Cambridge, MA Screening and Functional Analysis of 3D Models November 1-2, 2016 Cambridge, MA World Preclinical Congress - Europe November 14-16, 2016 Lisbon, Portugal Optimizing Leads and Predicting Drug Toxicity November 15-16, 2016 Lisbon, Portugal Use of CRISPR & RNAi for Drug Discovery November 15-16, 2016 Lisbon, Portugal DNA- and RNA-Based Vaccines December 6, 2016 Boston, MA Advances in Vaccine Technologies December 7-8, 2016 Boston, MA PepTalk-The Protein Science Week January 9-13, 2017 San Diego, CA Optimizing Biologics Formulation Development Engineering Genes and Hosts Characterization of Biotherapeutics Lyophilization and Emerging Drying Technologies Recombinant Protein Expression and Production Detection and Characterization of Particulates and Impurities Protein Aggregation and Emerging Analytical Tools Optimizing Expression Platforms 10 Cambridge Healthtech Institute

11 Emerging Technologies for Antibody Discovery PCR and NGS-Based Molecular Diagnostics Genomic Sample Prep, Assay Development and Validation Bioinformatics for Big Data Molecular Diagnostics Molecular Diagnostics for Infectious Disease Personalized Diagnostics Cancer Molecular Markers Circulating Tumor Cells and Liquid Biopsy Conferences by Series New Frontiers in CRISPR-Based Gene Editing Point-of-Care Diagnostics Genomic Knowledge Bases, Annotation and Interpretation Commercialization of Molecular Diagnostics Conferences by Date with Detail Leaders in Biobanking Congress September 7-9, 2016 Baltimore, MD Today, biospecimen collections are used by multiple research groups for various research aims, from basic research through clinical trials. Useful biosamples must be collected to maintain their molecular integrity for specific (or unknown) downstream analysis. Thus, the proper collection, processing, storage and tracking of biospecimens are critical components allowing researchers to better link molecular and clinical information. Cambridge Healthtech Institute s 8th International Leaders in Biobanking Congress: Applying Biospecimen Science to Advance Biomedical Research and Patient Care addresses biospecimen science, management, and applications, bringing together biomedical and biopharmaceutical researchers, regulators, biorepository managers and practitioners to investigate the best strategies for effective use of biospecimens within today s cutting-edge biomedical research. Healthtech.com/Biobanking Discovery on Target September 19-22, 2016 Boston, MA Cambridge Healthtech Institute will host the 14th Annual Discovery on Target event this September 19-22, 2016 in Boston, MA. Spanning four days, the event showcases current and emerging hot targets for the pharmaceutical industry. Over 1,100+ attendees (from 26 countries) composed of scientists/technologists, executives, directors, and managers from biopharma, academic, and healthcare organizations participate annually. The 2016 event is comprised of 17 conference tracks, 1 training seminar, 6 symposia, 17 short courses, an exhibit hall of 50+ companies, 135+ posters, and dedicated networking sessions. Discovery on Target assembles an impressive group of 300+ distinguished speakers who look forward to sharing their knowledge, best practices, and expertise with all attendees. DiscoveryOnTarget.com PEGS Korea September 20-22, 2016 Seoul, South Korea From the earlier regulatory successes of Adcetris and Kadcyla to the recent FDA approval of Blincyto, to the current clinical successes of Opdivo and Keytruda, the industry is abuzz with excitement and new hope. The successes of antibody-drug conjugates, bispecific antibodies and immunotherapy drugs and combinations are opening new doors for biotech companies to discover and develop breakthrough remedies. CHI s 2nd Annual PEGS Korea brings these exciting developments to light by gathering the industry s leading companies and institutions together to share their experiences from discovery to preclinical to clinical stage. Join us as we bring the event back to Seoul with even more case studies, more data, and more opportunities for collaborations. PEGSummitKorea.com Converged IT Summit October 24-26, 2016 San Diego, CA With research laboratories now capable of generating staggering amounts of data, the IT infrastructure required to store, move and process this information must become an integral part of strategic planning for success. The Second Annual Converged IT Summit will once again cover a broad range of topics framing the issues behind creating computational solutions for modern research methodologies. Our expanded program for 2016 will break out into two tracks, allowing in-depth exploration of both the Infrastructure and the Data Science needed to create a truly converged IT. Sessions will highlight technologies currently in use, how organizations are using them to accelerate discovery, efforts that have worked and those that have failed, organizational challenges and policies for research computing, and the art of converged infrastructure as a research tool. The Converged IT Summit is designed for professionals involved with strategic planning and implementation of IT technologies to support science. The goal is to deliver solutions to scientists that give them the freedom to discover. ConvergedITSummit.com Immunogenicity and Bioassay Summit October 26-28, 2016 Baltimore, MD Following year-on-year success, CHI presents the Eighth Annual Immunogenicity and Bioassay Summit 2016: 3 conferences, FDA presenters plus 40+ additional presentations, 15+ interactive breakout round table and panel discussions, short courses, exhibit/poster hall, and networking opportunities with 250+ delegates. Immunogenicity Prediction & Control is designed to help investigators design and select non-immunogenic products for early-stage decision making, while Immunogenicity Assessment & Clinical Relevance and Optimizing Bioassays for Biologics will enable investigators to overcome the complexities of immunogenicity assessment and bioassays, and develop programs that ensure their products are safe and efficacious, and satisfy regulatory requirements. ImmunogenicitySummit.com PEGS Europe October 31 - November 4, 2016 Lisbon, Portugal PEGS Europe is the largest European event covering all aspects of protein and antibody engineering. Over the last three years, participation at PEGS Europe has grown by more than 60%, and this year will be the largest ever. With a more-focused technical program, and double the coverage of the most popular PEGS topics, the 2016 event will feature 700 attendees, 200 technical presentations, 125 scientific posters, dedicated networking opportunities, exclusive exhibit & poster-viewing hours, and interactive roundtable, breakout, and panel discussions. PEGSummitEurope.com September 2016 February

12 Conferences by Date with Detail High-Content Analysis & 3D Screening October 31 - November 2, 2016 Cambridge, MA Cambridge Healthtech Institute is pleased to bring the longest-running High-Content Analysis & 3D Screening Conference to the hub of biotech and pharmaceutical research - Cambridge, MA. Now in its 14th year, the event explores the next generation in high-content and phenotypic screening and takes it to the third dimension. The High- Content Analysis and Phenotypic Screening stream will focus on the latest advancements in HCA technologies and applications, including phenotypic and high-content screening of 3D models, HCS image analysis and modeling, screening in physiologically-relevant cellular models, and case studies and strategies for successful phenotypic drug discovery. The stream on 3D cellular models and 3D screening features the latest spheroid, organoid and organotypic cell culture, and organon-a-chip technologies; patient-derived tumor models and human ipsc models for drug screening; and case studies in oncology drug discovery using 3D cellular models. HighContentAnalysis.com Strategic Resource Management & Portfolio Management October 31 - November 4, 2016 Philadelphia, PA Although investment in pharma R&D continues to increase, approval of new drugs remains relatively low. This productivity crisis presents new challenges to biopharma R&D in terms of resource management, forecasting, and capacity planning. To counteract the decline in new therapeutics and high risk of product failure, biopharma must adapt with improved performance planning, intelligent outsourcing, and new big data analytics aimed at developing strategic and flexible resource management systems. In an environment of declining revenues and uncertain commercial success, biopharma, device and R&D companies need to continuously evaluate their portfolios. Manufacturers must make tough decisions about which products and projects to pursue to optimize long-term revenue and reduce overall risk. Cambridge Healthtech Institute s and the BioPharma Strategy Series 13th Annual Strategic Resource Management and 10th Annual Portfolio Management Executive Forum attracts 100+ senior R&D executives from the pharma, biotech, device, IT, public and governmental communities who share best practices in project and portfolio management, R&D innovation, decision analysis, forecasting and the improvement of operational models. ExecutiveDecisionMaking.com World Preclinical Congress Europe November 14-16, 2016 Lisbon, Portugal The World Preclinical Congress Europe is a key networking event bringing together a global audience involved in preclinical research. It features conferences and short courses that cover the very latest in preclinical strategies and technologies, to enable better and faster decisions in drug discovery. With the broad range of conference s covered, the event offers a diverse cross-disciplinary environment for tackling translational challenges and sharing best practices. It s where preclinical minds meet discovery technologies to innovate traditional drug discovery by sharing ideas, showcasing new technologies, and fostering new collaborations. WorldPreclinicalEurope.com Advances in Prenatal Molecular Diagnostics November 29 - December 1, 2016 Cambridge, MA The growing acceptance and availability of cell-free DNA-based screening from maternal blood is having a dramatic impact on prenatal testing. One result has been the steady decline in the number of women choosing invasive testing, with growing shift away from karyotyping in favor of arrays, or in some cases sequencing, for analysis of these samples. The range of approaches being employed for cellfree DNA testing continues to grow, including the release of kits for in-house analysis and so-called second generation assays that provide much improved detection of sub-chromosomal anomalies. There has been a push to expand NIPT use beyond higher-risk pregnancies, as well as extending the range of genetic conditions reported from the tests, but such changes come at a price. Research into testing based on isolation of fetal cells from maternal blood has been underway for decades, and the discussion has been couched in terms of if this approach can be commercialized. At this meeting last year, for the first time, the conversation shifted to when this approach is commercialized as numerous groups reported substantial progress in achieving reliable isolation that would make this possible. Updated comparisons and examination of these issues, and the implementation of these different approaches, will again make for lively discussion and insight into where this field is headed and ways for researchers, test providers, clinicians and clinics to take these developments into consideration. Healthtech.com/Prenatal-Diagnostics Reproductive Genetic Diagnostics December 1-2, 2016 Cambridge, MA Couples experiencing infertility or failed pregnancy can now take advantage of a number of molecular diagnostic options to determine the health and wellness of their embryos as well as their own fertility. Cambridge Healthtech Institute s Second Annual Reproductive Genetic Diagnostics conference examines the latest in preimplantation diagnostic and screening technologies, including their applications in assessing mtdna load; determining aneuploidy through single-gene disorders; and assessing mosaicism. The meeting will also examine the potential for non-invasive PGD by blastocentesis, being developed in response to the potential effect biopsy and vitrification may have on the development of the embryo. There will be discussion on PGD for donor eggs, such as how much or how often testing should be done. The meeting will also cover advances in CRISPR, including current research and capabilities, as well as how this technology may or may not be used in the future. New this year, special attention will be paid to molecular diagnostics for finding infertility biomarkers in sperm and the uterus. Healthtech.com/Reproductive-Genetic-Diagnostics Biological & Chemical Sensors Summit December 5-7, 2016 La Jolla, CA Emerging technological innovations enabled by next generation sensors will define the landscape for the future commercialization of life changing products. The exponential growth of the global sensors market and the demand for next generation integrated systems is expected to reach $18 billion by Our international faculty of key industry and academic leaders will present the latest technological advancements of real-world applications within healthcare and emerging markets through our conference tracks, symposiums and tutorials. SensorsGlobalSummit.com 12 Cambridge Healthtech Institute

13 Conferences by Date with Detail Re-Entering Antibacterial Drug Development Summit December 7-9, 2016 Boston, MA By holding the Re-Entering Antibacterial Discovery and Development Summit, we at Cambridge Healthtech Institute are trying to contribute to the efforts to overcome the crisis of multidrug resistance, to revive the antibacterial pipeline, and to improve antimicrobial stewardship in the United States and worldwide. This Summit is designed as a forum for knowledge and opinion exchange among all stakeholders participating in discovery and development of new antibacterial agents. AntibacterialDrugDevelopmentSummit.com IMVACS: Immunization & Vaccine Summit December 7-9, 2016 Boston, MA Globally, immunization has proven to be the gateway to health for millions, and continued investment in vaccine development provides a measureable return in reducing the burden of disease and safeguarding human development. Today, more than ever, vaccine technology remains at the forefront of the confrontation against infectious disease. Cambridge Healthtech Institute s Eleventh Annual Immunization and Vaccine Summit will cover a range of topics in this evolving field, including the latest advancements and applications of vaccine technologies, development of effective vaccine adjuvants, and progress in DNA- and RNA-based vaccines. IMVACS.com PepTalk: The Protein Science Week January 9-13, 2017 San Diego, CA PepTalk: The Protein Science Week is one of the largest annual gatherings of protein science researchers in the world. In its 16th year, PepTalk attracts over 1,200 experts from academia, biotech and pharma who come together for one week of intensive learning and networking to discover new opportunities and promising partnerships. This event covers a wide spectrum, from upstream protein R&D science to downstream biologics. And, whether you re a world-renowned researcher or a current graduate student, PepTalk has something to offer. CHI-PepTalk.com SCOPE Summit for Clinical Ops Executives January 24-26, 2017 Miami, FL The 8th Annual SCOPE Summit, taking place January 24-26, 2017 in Miami, FL, will offer three stimulating days of in-depth discussions in 13 different conferences, 6 pre-conference workshops and 2 symposia focused on issues related to each aspect of clinical trial planning and management: Data Integration, Feasibility, Site Selection and Management, Patient Engagement, Recruitment and Retention, Mobile Tech, Project Management, Outsourcing, Forecasting, Budgeting and Contracting, Quality (QbD) in Trial Conduct, Risk-Based Monitoring, Post- Marketing Studies, Observational Research, Clinical Lab Services, Precision Medicine and Biomarker-Driven Trials. SCOPESummit.com Molecular Medicine Tri-Con February 19-24, 2017 San Francisco, CA Attracting over 3,500 drug discovery and development professionals from over 40 countries in 2016, the Tri-Conference has grown into a diverse event, focusing on Molecular Medicine, specifically on Discovery, Genomics, Diagnostics and Information Technology. If you are working in diagnostics and drug discovery, this is the must attend event of the year. TriConference.com PANIC: Practical Applications of NMR in Industry February 20-23, 2017 Hilton Head Island, SC Practical Applications of NMR in Industry Conference (PANIC) was initiated to provide an interactive forum for discussion of the latest developments in the use of NMR for practical applications to real problems faced by scientists in industry and research institutions. The emphasis is the practicality of the solution and getting the job done. This forum provides a venue for presentation of practical applications, and workshops for discussion of real-world experiences relevant to current product development needs with an opportunity to share case studies to drive further development of NMR technology. Solutionstate, solid-state, time-domain, and zero-field applications are all equally welcome at PANIC. PANIC also provides ample opportunity to network with peers and thought leaders from industry, regulatory, government, and academic institutions during networking receptions and breaks; engage in fruitful discussions during the poster sessions; and interact with sponsors and exhibitors. panicnmr.com ONE STOP SHOP AFFILIATED REPORTS COLLECTION for Over 1,000 Life Science Reports Spanning over 50 Research Areas An Essential Collection of Timely & Concise Reports Analyzing the Technologies, Markets, and Strategic Issues Driving R&D Productivity. Available through Insight Pharma Reports and our Network of Affiliated Reports. Insight Pharma Reports offers: 4 Market Data 4 Market Research 4 Pipeline Data 4 Custom Reports 4 Clinical Trial Data 4 Bundled Report Packages For more information, contact Daniel Miller at: DMiller@InsightPharmaReports.com or call (781) InsightPharmaReports.com Just some of the Reports Available Include: Alzheimer s Disease Biomarkers & Diagnostics BioPharma Strategy Biosimilars & Generic Markets Cancer Research and Therapeutics Chemistry Clinical Trials & Translational Medicine Data Mining Drug Discovery & Development Health IT Infectious Disease Medical Devices Multiple Sclerosis Ocular Pain Management Pharmaceutical Marketing Sequencing Vaccines...and many others September 2016 February

14 Short Course Schedule HOLD A COURSE AT YOUR FACILITY. For more information, please contact Edel O Regan at or eoregan@healthtech.com LEADERS IN BIOBANKING CONGRESS September 7, 2016 Baltimore, MD IMMUNOGENICITY AND BIOASSAY SUMMIT October 25 & 27, 2016 Baltimore, MD -- Managing a Viable Biobank -- Basics of Immunogenicity Testing -- Tools for Extracting, Amplifying and Detecting Minute Amounts of -- Challenges of Immunogenicity Assessment Circulating Nucleic Acids -- Advice on Putting Together an Integrated Summary of Immunogenicity DISCOVERY ON TARGET -- Strategic Bioassay Design and Analysis September 19 & 21, 2016 Boston, MA -- Immunology Basics for Chemists PEGS EUROPE -- Designing Peptide Therapeutics for Specific PPIs October 31 & November 3, 2016 Lisbon, Portugal -- Phenotypic Screening and Chemical Probe Development -- Cancer Immunotherapy -- Medical Dermatology Therapeutic R&D and Technical Innovation: Understanding Mechanisms, Novel Targets and Pathways & Industry Case Studies - Part One -- Mutation and Selection Strategies beyond Affinity Optimisation -- Designing Antibodies for Function and Low Risk of Immunogenicity -- GPCR Structure-Based Drug Discovery -- Transient Protein Expression: A Key Tool to Enable Rapid Protein -- RNA as a Small Molecule Drug Target Engineering -- Using IP Landscape Studied to Improve Your Confidence While Navigating a Crowded IP and Technology Space -- Medical Dermatology Therapeutic R&D and Technical Innovation: Early Formulation Considerations, Utilizing New Tech for Med Derm R&D, CMC, Formulation Development and Late Stage Clinical - Part Two -- Targeting of GPCRs with Monoclonal Antibodies -- Troubleshooting and Engineering of Antibody Constructs -- Engineering of Bispecific Antibodies -- Protein Purification Strategies: Dealing with Proteins that are Prone to Aggregate -- Protein Aggregation: Mechanism, Characterisation and Consequences -- Introduction to Targeted Covalent Inhibitors HIGH CONTENT ANALYSIS & 3D SCREENING -- Contact Lens Drug Delivery Systems October 31 - November 1, 2016 Cambridge, MA -- Introduction to Gene Editing -- Introduction to High-Content Phenotypic Screening -- Convergence of Immunotherapy and Epigenetics for Cancer Treatment -- Cancer Metabolism: Pathways, Targets and Clinical Updates -- Introduction to Allosteric Modulators and Biased Ligands of GPCRs -- Expert ThinkTank: How to Meet the Need for Physiologically Relevant Assays STRATEGIC RESOURCE & PORTFOLIO MANAGEMENT October 31 - November 1, 2016 Philadelphia, PA -- Functional Screening Strategies Using CRISPR and RNAi -- Project Portfolio Management Certification Master Class -- Challenges and Opportunities in DNA Methyl Transferase (DNMT) Inhibitors as Therapeutics WORLD PRECLINICAL CONGRESS EUROPE -- SVPs, Aggregates and Impurities: Measurement, Characterization, November 14-15, 2016 Lisbon, Portugal PEGS KOREA -- Humanized Mouse Models: Technology and Applications in Preclinical Assessment of Cancer Immunotherapy September 21, 2016 Seoul, South Korea -- New Technologies for Improving Drug Safety Screening -- Troubleshooting and Engineering of Antibody Constructs -- Functional Screening Strategies Using CRISPR and RNAi CONVERGED IT SUMMIT October 24, 2016 San Diego, CA RE-ENTERING ANTIBACTERIAL DISCOVERY & DEVELOPMENT SUMMIT December 6 & 8, 2016 Boston, MA -- Designing Storage Solutions for Life Sciences -- From White Powder to Drug: The Path from Antibacterial -- Foundational Services for Bioinformatics in the AWS Cloud Discovery to the Clinic -- Funding Opportunities for Antibacterial Research 14 Cambridge Healthtech Institute

15 Short Course Schedule IMVACS: IMMUNIZATION & VACCINE SUMMIT December Boston, MA SCOPE: SUMMIT FOR CLINICAL OPS EXECUTIVES January 23, 2017 Miami, FL -- Expert ThinkTank: Zika Vaccine Development -- Implementing Social Media, Digital Marketing and Other New Strategies for Patient Recruitment PEPTALK: THE PROTEIN SCIENCE WEEK -- How to Implement RBM on a Budget January 8-10, 2017 San Diego, CA -- Clinical Trial Protocol Optimization -- Production Challenges for Complex Biologics: ADCs, Bispecifics and Fusion Proteins -- A Modern Approach to Biologics Formulation Development -- Managing Trials in Oncology and Immuno-Oncology -- Developing Your Custom Strategy for Requests for Proposals (RFPs) through to Final Contract -- A Lean Approach to Lab Management -- How to Accelerate Digital Health Innovation in Your Company -- New Enzyme Design, Discovery and Development -- A Lean Approach to Lab Management MOLECULAR MEDICINE TRI-CONFERENCE -- New Enzyme Design, Discovery and Development February San Francisco, CA -- Ensuring Accelerated and Successful Drug Product Development of Biologics Integrated Formulation Development, Process and Packaging Design -- Next-Generation Sequencing of Antibody Libraries: Details on Experimental and Bioinformatic Methods -- Troubleshooting and Engineering of Antibody Constructs -- Protein Aggregation: Mechanism, Characterization and Consequences -- Transient Protein Production in Mammalian Cells -- Plant-Based Products: From Biosimilars to Biobetters -- Short Course Line-Up TBA SUBSCRIBE TODAY Daily and Breaking News Complimentary Newsletters and ebooks Free Industry Whitepapers, Podcasts, Market Survey Results, and Webinars Online Product Directory PUBLICATIONS AVAILABLE FROM CLINICAL INFORMATICS NEWS Clinical Trials to the Clinic Diagnostics World Beyond the Odyssey: Emerging Technologies in Diagnostics To learn more about Bio-IT World, Clinical Informatics News, and Diagnostics World digital advertising and lead generation programs, download the Media Kit at: Healthtech Publishing 250 First Avenue, Suite 300, Needham, MA T: or toll-free in the U.S F: September 2016 February

16 CHI healthtech.com 250 First Avenue, Suite 300 Needham, Massachusetts USA Phone: About Cambridge Healthtech Institute Your Life Science Network Cambridge Healthtech Institute (CHI) is the preeminent life science network for leading researchers and business experts from top pharmaceutical, biotech, CROs, academia, and niche service providers. CHI is renowned for its vast conference portfolio held worldwide including PepTalk, Molecular Medicine Tri-CON, SCOPE Summit, Bio-IT World Conference & Expo, PEGS Summit, Drug Discovery Chemistry, Biomarker World Congress, World Pharmaceutical Congress, Next Generation Dx Summit and Discovery on Target. ADDITIONAL DIVISIONS OF CHI INCLUDE knowledgefoundation.com barnettinternational.com healthtechpublishing.com insightpharmareports.com CHI is a division of Cambridge Innovation Institute