Sartopure PP3 Prefiltration Performance Raised to the Power of 3
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1 Sartopure PP3 Prefiltration Performance Raised to the Power of 3
2 Sartopure PP3 The New Dimension in Prefiltration The new Sartopure PP3 prefilter line is the result of decades of experience in prefiltration technologies specifically developed for pharmaceutical and biopharmaceutical applications. These high-performance prefilters uncompromisingly deliver the highest total throughput, while providing the ultimate in downstream protective capabilities. The outstanding performance of the Sartopure PP3 fleece significantly reduces filtration area and product contact time, maximizing downstream product yield. The benefits: fewer prefilter change-outs and more filtration power substantially lower your overall cost of prefiltration. Advantages Improves your product quality Increases product yield Extends the lifetime of downstream equipment Reduces your filter change-outs
3 Applications Early clarification steps in vaccine production Blood and plasma fractionation
4 Sartopure PP3 The New Dimension in Prefiltration The new Sartopure PP3 prefilter line is the result of decades of experience in prefiltration technologies specifically developed for pharmaceutical and biopharmaceutical applications. These high-performance prefilters uncompromisingly deliver the highest total throughput, while providing the ultimate in downstream protective capabilities. The outstanding performance of the Sartopure PP3 fleece significantly reduces filtration area and product contact time, maximizing downstream product yield. The benefits: fewer prefilter change-outs and more filtration power substantially lower your overall cost of prefiltration. The broadest range of retention rates from 0.45 µm to 100 µm. highest ratio of active filtration surface. Advantages Improves your product quality Increases product yield µm Extends the lifetime of downstream equipment Reduces your filter change-outs
5 Plus, the High-Performance Fleece Material Fleece designed to outperform conventional non-woven materials. Features µm Unmatched in the following areas: Total throughput Clarification capabilities Protection of downstream equipment
6 Maximum Protection at a Minimum Cost The new high-performance fleece materials in Sartopure PP3 show significantly increased total throughput and outstanding effectiveness in protecting your downstream equipment. As a result, Sartopure PP3 needs only a fraction of the filtration area to increase your product yield and extend the lifetime of your downstream equipment. This translates to substantial cost savings. Protection of Downstream Equipment The Sartopure PP3 series provides the highest robustness in prefiltration applications based on the unique retention performance of its new fleece materials. They retain particles with the highest efficiency, even under fluctuating process conditions. This ensures safe and reliable operation and a significantly extended lifetime of all downstream equipment. Turbidity Reduction Competitor B Competitor A Competitor C PP3 Total Throughput Fewer Change-outs The optimally structured fleece material provides the highest possible active filtration surface per area. This results in an impressive reduction in filtration area and in the number of filters used, which translates to much lower costs per liter. Costs Competitor A Competitor B Competitor C PP3 Filter Reduction
7 Family Overview SartoScale Filterability device with a filtration area of 17 cm 2 (0.02 ft 2 ). This flat filter capsule is mainly used for filterability (indicator) trials. Capsules Cartridges Standard format for filtration applications using stainless steel filter housings. Large filtration area of 0.4 m 2 to 1.95 m 2 (4.3 ft 2 to 21 ft 2 ) per cartridge. Ready-to-use, small-scale format with a filtration area of m 2 to m 2 (0.13 ft 2 to 0.39 ft 2 ) for scale-up and/or verification trials and small-volume applications. MidiCaps MaxiCaps Ready-to-use, large-scale format with a filtration area of 0.4 m 2 to 1.95 m 2 (4.3 ft 2 to 21 ft 2 ) for singleuse processes. Ready-to-use, medium-scale format with a filtration area of 0.04 m 2 to 0.42 m 2 (0.43 ft 2 to 4.5 ft 2 ) for single-use processes. T-Style MaxiCaps Ready-to-use, large-scale format for single-use processes; with a filtration area of 0.4 m 2 to 1.95 m 2 (4.3 ft 2 to 21 ft 2 ).
8 Application Matrix Process Application Prefilters Bioburden Reduction Biotech mab, Recombinant Proteins, Vaccines Viral Vaccines Cell Cultures Sartoclean Sartopure Sartofine Sartoguard GF CA PP3 GF Plus PP PES GF NF Media preparation Cell cultivation fermentation ph adjustment Cell removal clarification Buffer preparation Downstream intermediates (protection of columns, crossflow) Prefiltration prior to virus filtration Form and fill Media preparation Cell cultivation fermentation ph adjustment Cell removal clarification Buffer preparation Downstream intermediates (protection of columns, crossflow) Form and fill Pharma Ophthalmics Form and fill SVP LVP Form and fill API Form and fill Blood and Plasma Albumin Globulins Clotting Factors Other Intermediate process filtration (protection of columns, crossflow) Prefiltration prior to virus filtration Form and fill Intermediate process filtration (protection of columns, crossflow) Prefiltration prior to virus filtration Form and fill Water Oily formulations Solvents Sterile venting Gas filtration Recommended Alternatively recommended
9 Sterile Filters for Liquids Mycoplasma Retentive Filters Filters for Air Other Types of Gas Sartopore Platinum** Sartopore 2 Sartobran P Sartolon Sartopore 2 Sartopure Sartofluor 0.2 µm HF XLG XLI 0.2 µm XLM GA GA LG * * Sterile applications ** Sartopore 2 alternatively recommended
10 Ordering Information Type Retention Rate [μm] Qty. per Box [Units] Capsules Px--**--B Px--**--B Px--**--B Px--**--B Px--**--B Px--**--B Px--**--B 20 5 Mini Cartridges Px------B Px------B Px------B Px------B Px------B Px------B Px------B Px------B Px------B Cartridges 505**06Px **05Px **03Px **02Px **42Px **01Px **20Px **50Px **98Px Type Retention Rate [μm] Qty. per Box [Units] MidiCaps Px--**--A Px--**--A Px--**--A Px--**--A Px--**--A Px--**--A Px--**--A 20 4 MaxiCaps Px--** Px--** Px--** Px--** Px--** Px--** Px--** 20 1 T-Style MaxiCaps Px--** Px--** Px--** Px--** Px--** Px--** Px--** 20 1 ** Connector styles (the first code letter indicates the inlet; the second, the outlet) x Size of T-Style MaxiCaps and MidiCaps (Size 0 is available only in boxes of two. Then add --V instead of --A to the order code.) Cartridges T-Style MaxiCaps Adapter 25 2-flange bayonet adapter with 226 double O-ring Connector Type S Tri-Clamp, 50 mm (1 1/2 ) Connector Type O Connector Type Y 1 Single stepped hose barb, 1 Single stepped hose barb, 1 MidiCaps Connector Type S Tri-Clamp, 50 mm (1 1/2 ) Connector Type F Tri-Clamp 25 mm (1 ) Connector Type O Single stepped hose barb, 1 Connector Type O Single stepped hose barb, 1 Connector Type F Tri-Clamp, 25 mm (3/4 ) SartoScale MaxiScale Capsule Size 4 Connector Type F Tri-Clamp, 25 mm (3/4 ) Connector Type H Multiple stepped hose barb, 4 Connector Type O Multiple stepped hose barb, 3 Connector Type S Tri-Clamp, 25 mm (3/4 ) Sartorius Stedim Biotech GmbH August-Spindler-Strasse Goettingen, Germany Phone Fax USA Toll-Free UK France Italy Spain Russian Federation Japan China Specifications subject to change without notice. Printed and copyrighted by Sartorius Stedim Biotech GmbH. W Publication No.: SPK1564-e Order No.: Ver
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