The Biotechnology Industry in Taiwan

Transcription

1 The Biotechnology Industry in Taiwan Dr. Julie C. L. SUN Taiwan Institute of Economic Research

2 Development of Taiwan Biotech Industry 1982 Eight Key Technologies.... Biotechnology Hepatitis prevention 1995 Action Plan for Biotechnology Industry Development Advisory Committee for Promoting Biotechnology Industry, Executive Yuan 1996 Biotechnology And Pharmaceutical Industries Program Office (BPIPO), MOEA 2003 Action Plan for Biotechnology Industry Development (amended) 2005 Bio Taiwan Commisson (BTC) BioMedical Island Plan Government Measures 1984 Development Center for Biotechnology (DCB) Pharmaceutical Industry Technology And Development Center (PITDC) 1996 National Health Research Institutes (NHRI) 1998 Center for Drug Evaluation (CDE) 1999 Biomedical Engineering Research Center, Industrial Technology Research Institute (ITRI) 2003 Genomics Research Center, Academia Sinica (GRCAS) Food Industry Research and Development Institute (FIRDI), Bio-resources Collection and Research Center

3 Current Status of Taiwan s s Biotech Related Industries (2005 f ) Industry sector New Biotechnology Pharmaceuticals Medical Devices Total Revenue 1,212 1,940 1,850 5,002 No. of Companies ,152 Workforce (persons) 8,090 14,995 15,000 38,085 Export Value ,675 Import Value 501 1,791 1,073 3,365 Domestic Sales vs. Export (Unit: million US$) 60:40 87:13 55:45 67:33 Domestic Market 1,225 3,383 2,084 6,692 Source: rearranged by BPIPO,2006 1USD:1NTD=1: Taiwan Institute of Economic Research 2

4 Investments in Taiwan Biotech Industry Investment Amount (Unit: million US$) year Source: Biotechnology & Pharmaceutical Industries Program Office, MOEA Taiwan Institute of Economic Research 3

5 Bio Clusters in Taiwan Hsinchu Biomedical Science Park Hsinchu Science-Based Industrial Park Taichung Science-Based Industrial Park Nangang Software Park Biotech Plaza Yilan Marine Biotechnology Park Medicinal Herb Biotech Park Changhua National Flower Park Taiwan Orchid Biotech Park Taitung Deep Ocean Water Technology Park Tainan Science-Based Industrial Park Kaohsiung Biotech Park Ping Tong Agricultural Biotechnology Park Completed In construction Planned Being assessed Source: IDB, MOEA Taiwan Institute of Economic Research 4

6 Taiwan s s Life Science Research >150 Universities 35,000 graduates/year (~7,000 graduates/ year in life sciences) 17 Large Medical Centers 7 Certified Clinical Trial Hospitals More then 20 Research Institutes: -ITRI, NHRI, DCB, Academia Sinica, FIRDI, PITDC, CDE, etc. Taiwan Institute of Economic Research 5

7 Highly Educated and Innovative Workforce Life Science talents supply Life Science graduates Source: 2004 Development Center for Biotechnology ITIS Project B.S. M.S. Ph.D. Total 2005f 4,258 2, , f 4,684 2, , f 5,105 2, , domestic life science-related departments in 2005(of which 57 were graduate institutes). 18th on the number of major scientific theses and dissertations presented (2003) -12,392 (Total) -5,110 (Biotech) 4th in patents issued in US(2004) Taiwan Institute of Economic Research 6

8 Investment Incentives 1 (1) Tax Benefits Tax deduction up to 30% of the R&D and HRD expenses Tax deduction of 5%-7% for the investments in automation, pollution control, energy-saving, etc. (2) R&D Grants Programs: Grants for Development of Innovative Products Grants for Industrial Technology Development Program Grants for Conventional Industry Technology Development Grants for Small Business Innovation Research (SBIR) Grants for Industrial Technology Innovation Centers Taiwan Institute of Economic Research 7

9 Investment Incentives 2 (3) Joint Investment from the Government Fund The Executive Yuan s Development Fund can join investments in biotech companies and venture capitals. (4) Low Interest Loan Loan for promoting industrial research and development Loan for medium-long term investment (Council For Economic Planning and Development) Taiwan Institute of Economic Research 8

10 Investment Incentives 3 (5) Industrial Park Rent Discount Program Zero rent for the first two years; 40% discount for the 3 rd and the 4 th years; 20% discount for the 5 th and the 6 th year. The rent paid may be used to offset the purchase price (6) Listing / OTC Trading Technological enterprises that have successfully developed marketable products / technologies 27 biotechnology companies are currently listed or OTC traded Taiwan Institute of Economic Research 9

11 Why Taiwan? Superior geographic gateway to the Asia-Pacific region Ideal springboard into mainland China markets Well-integrated industrial clusters Abundant high-quality human resources Excellent R&D and commercialization capabilities High quality medical centers for clinical trials Strong government support Taiwan Institute of Economic Research 10

12 Biotechnology Industry Study Centre, Taiwan Institute of Economic Research

13 National Science And Technology Program For Agricultural Biotechnology (NSTAB) Taiwan Institute of Economic Research 12

14 Taiwan Institute of Economic Research 13

15 The Development Framework for Modified Breed Modified breed development Application in different industries Genomics /proteomics Gene/Trait identification Trait optimization Model system Target material Advanced development Field trial Modibreed (Mkt) Growing/ Processing Commercialization Agricultural products Industrial products Medical products Genome sequence analysis cdna analysis EST analysis Genetic marker Phenotype screening Expression analysis Gene tagging Mutagenic manipulation Crossing tech Vector system Transformation tech Promoter Asexual reproduction tech Sexual reproduction tech Safety evaluation Environment evaluation Product Information Instruments Reagents Software Tool Microarray Lab-on-a-chip Nucleic acid amplification ELISA Material Library Taiwan Institute of Economic Research 14

16 The Development Framework for Functional Food Genomics / Proteomics/ Metabolomics Target Identification Sources Finding & Research Bio-activity Validation Raw material Component Product Type & Manufacture Safety & Efficacy / Regulation Marketing Clinical Trial / Regulation Pharmaceutical Marketing Screening In vitro platform Productivity Expand Products Source Identification Sources Purification Culture and Incubation Information Biological Kits Bio Chip Computer Simulation Data Bank In Vivo/ Animal Platform Safety Evaluation Tools Extraction Formulation Compaction In Vivo/Human Platform Analysis Data Analysis Instrument Taiwan Institute of Economic Research 15

17 The Development Framework for Vaccine Antigen identification Immunogen development Formulation / Scale-up Laboratory trial Field trial / Regulation Marketing Koch s ostulates Inactivation Delivery systems Product Genomic analysis Attenuation Adjuvants Proteomic analysis Peptide synthesis Fermentation Information Computer simulation Recombinant DNA Therapeutic antibody Safety validation Protectivity validation Tools Expression analysis Stability validation Immunogenicity analysis Instruments Reagents Software In vivo platform Microbe bank Nucleic acid amplification, detection Western blot analysis ELISA Cell sorting systems Taiwan Institute of Economic Research 16

18 All in all, a bright future for cooperation between US and Taiwan! Taiwan Institute of Economic Research 17

19 Thank you for your attention! Taiwan Institute of Economic Research Biotechnology Industry Study Centre TEL: FAX: