L A B W A T E R ULTRA-PURE WATER. PURELAB Ultra. Ultra-Pure Water Polishing System. The Laboratory Water Specialists

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1 ULTRA-PURE WATER L A B W A T E R PURELAB Ultra Ultra-Pure Water Polishing System The Laboratory Water Specialists

2 PURELABultra The PURELAB Ultra The new PURELAB Ultra is the state of the art ultra-pure water purification system for your most critical applications. It incorporates many unique and innovative features that set it apart from other systems and guarantee pure water. The PURELAB Ultra range has 5 models specifically designed to deliver the ideal water quality for your bioscience or analytical requirements. With the PURELAB Ultra there is no need to compromise. Model Typical Applications Water Purity: Resistivity at 25 o C TOC (RO pretreatment) Bacteria Bacterial endotoxin Particles Flow Rates Genetic Life Science Bioscience Molecular biology, microbiology, PCR, electrophoresis, DNA sequencing, mammalian cell culture, cell and culture media preparation, in-vitro fertilization, monoclonal antibody production <3 ppb <10 ppb <1 CFU/ml <1 CFU/ml <0.001 EU/ml <0.01 EU/ml Ultrafilter 0.2µm point-of-use filter 2 Up to 2 liters/min 1 With point-of-use filter 2 Optional Analytic Analysis Ionic Ultra-trace and trace inorganic and organic analysis, HPLC, GC-MS, ICP-MS, CF-AAS, TOC analysis, IC, electrochemistry <2 ppb <5 ppb <1 CFU/ml <1 CFU/ml 0.05µm ultra-microfilter 0.2µm point-of-use filter 2 Up to 2 liters/min General Science Scientific General analysis, IC, AAS, ICP-ES, standard buffers <15 ppb <1 CFU/ml 1 0.2µm point-of-use filter 2 Up to 2 liters/min

3 The Intelligent Pure Water Polishing System* Multi-stage monitoring with dual purification cartridge packs to ensure all trace impurities are removed Real time TOC monitoring that continuously monitors organic purity Automatic pre-rinse of feedwater to purge static water on start-up Preset volume dispense program allows routine volumes to be dispensed automatically Sensitive electronic dispense offers accurate flow control up to 2 liters/min Purification cartridge packs Easy to fit and change Easy front access Light weight purification cartridge pack Unique memory data tag Complete automated system sanitization Validation Support Features PIN coded protected set points Cartridge traceability Real time printed records Automatic calibration continually verifying electronic circuitry * Designed and manufactured under an ISO 9001 total quality system. Tested to comply with CE, EMC, EN 61010, ETL (UL, CSA), PIRA and other standards as appropriate.

4 PURELABultra GUARANTEED WATER PURITY ELGA understands the importance of maintaining the highest purity consistently. The design of the PURELAB Ultra results from our tradition of close collaboration with research scientists in understanding their changing application requirements. As well as being a leader in laboratory water technology, as part of Veolia Water, we are able to combine an unrivalled knowledge of process water needs in the pharmaceutical, food, beverage and new electronic markets. The result is a combination of unique benefits only available in the PURELAB Ultra. Multi-stage Monitoring of resistivity gives the user greater economy, convenience and security. At the end of the first purification cartridge pack s life, it is replaced by the second pack, which in turn is replaced by a new pack. Therefore, a pack towards the end of its life is never the final purification stage. This allows better use of the media and removes the need to replace a pack the moment it indicates exhaustion. Sanitization can only be fully effective if all internal wetted components are included in the disinfection regime. The PURELAB Ultra uniquely provides this assurance. Automatic Pre-rinse on start-up purges static feedwater to maximize the long-term efficiency of the ultra-purification process. Particularly beneficial for polishing SDI deionized water feeds. Real Time TOC Monitoring is unique in the PURELAB Ultra giving confidence in the water quality you dispense. Validation is a key requirement in many laboratories. In addition to offering standard documentation packages to help meet GLP, FDA or other validation protocols, PURELAB Ultra incorporates key features to assist with system validation. PIN coded access to software set points prevents unauthorized changes to operation or system settings. Unique data tags provide full traceability and history of each cartridge for GLP and other validation requirements. RS232 data port to enable downloading of data to PC or printer. On board continuous calibration to traceable references to verify electronic circuitry. A MODEL TO MEET YOUR NEEDS Inside each system our dual purification cartridge packs incorporate high quality organic absorbents, ion exchange resins and membrane processes to purify the water to in order to meet ASTM Type I, ISO 3696, NCCLS Type I and USP25 specifications. There is a range of alternative media to polish the water to meet specific feedwater and application requirements. All models recirculate the pure water to maintain consistent peak quality. All PURELAB Ultra models polish purified feedwater, produced usually by reverse osmosis or deionization systems such as ELGA s PURELAB Prima or PURELAB Option. With five models in the PURELAB Ultra range you can choose a specification that delivers optimum water quality for your needs.

5 PURELAB Ultra Genetic and Bioscience Both models feature ultrafiltration which removes the requirement for DEPC treatment in applications such as DNA sequencing, PCR and electrophoresis and removes endotoxins making the purified water suitable for critical cell culture applications such as in-vitro fertilization and monoclonal antibody production. Full spectrum UV photo-oxidation technology in the PURELAB Ultra Genetic provides oxidation of organic contaminants at 185nm and excellent bacterial control. The product water is also suitable for many analytical applications. Assay of RNase in water Method: Incubate substrate E. coli 18S + 28S ribosomal RNA in various dilutions of RNase and samples of ultra-pure water. Separate resulting fragments of RNA by electrophoresis. Results: /10 10 RNase 2 1/10 11 RNase 3 1/10 12 RNase 4 DEPC Treated Water 5 PURELAB Ultra Genetic PURELAB Ultra Analytic and Ionic The PURELAB Ultra Analytic incorporates full spectrum UV photo-oxidation technology for oxidation of organic contaminants at 185nm plus bacteria control at 254nm, and ultra-microfiltration to remove colloids and bacteria. The purified water has extremely low levels of inorganic and organic contaminants for the most demanding HPLC, GC-MS and other ultratrace organic applications. Conductivity Single figure ppt levels of common ions in PURELAB Ultra purified water Sodium Ammonium Potassium Magnesium Standard PURELAB Ultra ppt ppt Na NH K 50 2 Mg 50 <1 Ca Calcium The PURELAB Ultra Ionic features 254nm UV photooxidation technology and ultra microfiltration to deliver pure water for critical inorganic analytical applications using ICP-MS, Flameless Atomic Absorption Spectrophotometry and Trace Ion Chromatography. Time (min) PURELAB Ultra Measured using a Dionex DX500 following pre-concentration PURELAB Ultra Scientific Suitable for applications such as AAS, ICP-ES and Ion Chromatography. ULTRA-PURE WATER BY MULTIPLE PURIFICATION TECHNOLOGIES Life Science Analysis General Science Model Genetic Bioscience Analytic Ionic Scientific Purification Technologies: Dual purification cartridges Photo-oxidation 185/254nm UV 185/254nm UV 185/254nm UV 254nm UV Ultrafilter Ultra-microfilter 0.2µm optional point-of-use filter Recirculation System Monitoring: Interstage water purity Product water purity Real time TOC

6 PURELABultra PRECISION DISPENSING AT YOUR FINGERTIPS All PURELAB Ultra systems feature the very latest precision dispensing technology with large head clearance to accept a wide range of containers. You have fingertip control over the flow rate from a continuous high rate of 2 liters per minute for larger containers to a drop-by-drop flow for precision dispensing. You can also pre-program the system to conveniently deliver specific quantities for regular applications. EASY MAINTENANCE Maintenance on the PURELAB Ultra is very simple and straightforward, freeing up your time. Direct access from the front-entry service doors, plus quick-fit connections, allows easy replacement of consumables. In addition the PURELAB Ultra has an easy-to-use, automated process for sanitization which will save even more time. COMPACT VERSATILE DESIGN PURELAB Ultra systems are space saving in design with multiple positioning options. They can be mounted on a bench, under a bench with remote control option or on a wall whichever is most convenient for you. There is also a wide range of accessories to further complement the PURELAB Ultra. TS

7 TECHNICAL SPECIFICATIONS Life Science Analysis General Science Model Genetic Bioscience Analytic Ionic Scientific Performance Specifications Inorganics at 25 o C TOC (RO pretreatment) Bacteria Bacterial Endotoxin ph Product Specifications Weight (Ex purification packs) Dimensions Operational Mode Displays Safety Features System Monitoring Dispense Flows Capacity (per single cartridge pack change) Feedwater Specifications Source Maximum FI Maximum Conductivity (RO Feed) Minimum Resistivity (SDI Feed) Maximum TOC Maximum Free Chlorine Maximum Carbon Dioxide Maximum Silica Particulates Temperature Pressure Maximum Pressure Minimum <3 ppb <1 CFU/ml <0.001 EU/ml 15.0 kg <10 ppb <1 CFU/ml <0.01 EU/ml 14.5 kg <2 ppb <1 CFU/ml 15.0 kg <5 ppb <1 CFU/ml 14.5 kg Height: 490mm Width: 410mm Depth: 365mm <15 ppb <1 CFU/ml kg Power on, process on, intermittent operation, recirculation, dispense flow rate, volumetric dispense % full, sanitization, feedwater flush Power fail-safe, low feed shut-off, audio-visual alarms, PIN coded system settings, dispense shut-off during disinfection, auto-restart Water purity between purification cartridges (M -cm or µs/cm), product water purity (M -cm or µs/cm), product water temperature (ºC), continuous TOC monitoring (Genetic and Analytic models only), consumable change reminders, continuous calibration of water quality electronics to traceable references, date and time Variable from one droplet to 2 liters/min 56,000 liters >18.2 M -cm µs/cm at ph 7.0 Designed to polish RO permeate, deionized, SDI or distilled feedwater (ELGA recommends the use of a PURELAB Prima or PURELAB Option system). <1 (0.2 micron membrane prefilter is recommended for all non-ro feeds) 50 µs/cm 1 M -cm 50 ppb <0.05 ppm 30 ppm 2 ppm Filtration down to 0.2 micron advisable to protect internal and/or point-of-use filters 1 40ºC 0.7 bar (10 psi) 0.07 bar (1 psi) or flooded suction to the recirculation pump 1 With point-of-use filter

8 THE SINGLE SOURCE SOLUTION PURELABultra Within the ELGA family of water purification systems, the PURELAB Ultra provides peak water purity for your most demanding applications. ELGA also manufactures a wide range of other systems for general laboratory grade and primary grade water. Every ELGA system has been carefully designed to give you uncompromising water quality in a cost-effective, convenient, and easy to use package. With a network of over 600 service centers worldwide, ELGA provides an unrivalled package of service and support for its range of pure water systems. Whatever support you require, ELGA s team of water treatment experts will respond quickly to ensure your total satisfaction with our products and services. With our wide range of technologies, products and services, we can provide the right solution tailored to your own specific pure water needs. Contact us today for further information on the water purification systems featured in this brochure or for details of other models in the range. BR/P-ULTRA/JAN05/E4 LITR ULTRA-PURE SYSTEMS GENERAL LABORATORY GRADE SYSTEMS PRIMARY GRADE SYSTEMS Contact your nearest ELGA LabWater representative at: GLOBAL OPERATIONS CENTER ELGA Tel Fax NORTH AMERICA USFILTER Customer Service Technical Support Ext 5000 AUSTRALIA Tel Fax AUSTRIA Tel Fax BENELUX Tel Fax BRAZIL Tel Fax CHINA Tel Fax DENMARK Tel Fax FINLAND Tel Fax Visit our website at FRANCE Tel Fax GERMANY Tel Fax IRELAND Tel Fax MEXICO Tel Fax SPAIN Tel Fax us on info@elgalabwater.com ELGA is the global laboratory water brand name of Veolia Water. Owing to a policy of continual improvement, we reserve the right to amend the specifications given in this brochure. UAE Tel Fax UK Tel Fax