Les opportunités dans le domaine de la santé

Transcription

1 Horizon-2020 appels 2018 Les opportunités dans le domaine de la santé Les slides seront disponibles sur le site web du NCP-Wallonie Emilie ETOUNDI

2 ! Versions provisoires et non officiellement adoptées par la Commission Européenne. Modifications possibles!!! - 2 -

3 Crosscutting activities - 3 -

4 Crosscutting activities - 4 -

5 e-health Societal Challenge 1 SC1 Health, demographic change and well-being Call 1: Better health care, economic growth and sustainable health systems Call 2: Digital transformation in Health and Care 100M Call 3: Trusted digital solutions and Cybersecurity in Health and Care 36M 442M (ehealth: 42M ) - 5 -

6 Societal Challenge 1 Horizon-2020 SC1 Projets avec des Wallons Towards tailored, needsdriven, safer and costeffective management of Crohn s disease A systems medicine approach to chronic inflammatory diseases - 6 -

7 Call 1 Better health and care, economic growth and sustainable health Better health and care, economic growth and sustainable health Contributing to better health and healthy ageing Developing sustainable health and care systems and growth opportunities for the health and care related industries Translating new knowledge into innovative applications and accelerating large-scale uptake and deployment in different health and care settings Making health and care systems and services more accessible, responsive and efficient in Europe and beyond 5 main priorities Personalised medicine Innovative health and care industry Infectious diseases and improving global health Innovative health and care systems integration of care Decoding the role of the environment for health and well-being

8 Exécution du projet Societal Challenge 1 Eté Fin 2018 Ouverture appels Dépôt des projets Résultat de l évaluation Signature contrat Structuration idée et budget Identification partenaires Rédaction Évaluation Finalisation du contrat 8-8 -

9 Call 1 Better health and care, economic growth and sustainable health SC1-BHC : Exploiting research outcomes and application potential of the human microbiome for personalised prediction and prevention of diseases Define/understand balanced healthy conditions to deliver personalised approaches and clinical tools to predict and prevent diseases Use of existing data (large scale international initiatives, existing microbiome project) Generation of new data with various approaches Collaboration and synergies between scientists across disciplines, sectors and around the globe Sex & gender, country-specific issues Participation of SMEs RIA : 10-15M : : 3-5 projets - 9 -

10 Call 1 Better health and care, economic growth and sustainable health SC1-HCO : Actions in support of the International Consortium for Personalised Medicine International aspects Building links with third countries based on advantages of collaboration in PM Promoting international standards in PM and uptake of PM 2018: CELAC / 2019: China Regional aspects Establish and support networking between regions in EU (remote and sparsely populated regions) Structure PM application at regional level

11 Healthcare- and pharma-economic models for PM Support new health- and pharma economic models for PM to develop relevant health financing models Analyse mid- and long- term impacts of PM innovative products Ensure patients access, data safety and financial sustainabilty of public health systems Based on existing work/initiatives Dissemination! CSA : 1,5-2M : : 4 projets

12 Call 1 Better health and care, economic growth and sustainable health SC1-BHC : Innovation platforms for advanced therapies of the future Use new knowledge and technologies to introduce greater innovation into the advanced therapy development chain as a basis for tackling diseases and conditions affecting large patients groups. Create knowledge and exploitation platforms around innovative concepts for advanced therapy development build possible new therapeutic approaches and overcome development bottlenecks All steps of the innovation chain Business model for exploiting results + appropriate outreach and public information activities RIA : 12-15M : : 3 projets

13 Call 1 Better health and care, economic growth and sustainable health SC1-HCO : Strengthen Regulatory Science and support for regulatory Scientific Advice Better address regulatory sciences in medical teaching and training as well as in biomedical research for innovations to reach the patients in a timely and efficient manner Comprehensive inventory of existing support activities for regulatory Scientific Advice and protocol assistance in Europe Develop and deliver efficient training programmes to strengthen Regulatory Sciences Mechanisms to support academic groups in regulatory Scientific Advice and protocol assistance procedures Coordinate and/or harmonise efforts among MS CSA : 1,5-2M : : 1 projet

14 Call 1 Better health and care, economic growth and sustainable health SC1-BHC : New anti-infective agents for prevention and/or treatment of neglected infectious diseases (NID) Development of new, more effective and affordable treatments and vaccines for NIDs for uptake by limited-resources health systems. Late preclinical and early clinical (up to phase 1) Already existing lead drug and vaccine candidates Take into account the downstream constraints for effective deployment and uptake At least one organisation from disease-endemic countries, in particular Latin America & Africa Lump sum RIA : 5-10M : : (2 phases) : 5-10 projets

15 Call 1 Better health and care, economic growth and sustainable health SC1-BHC : Global Alliance for Chronic Diseases (GADC) scaling-up of evidence-based health interventions at population level for the prevention, detection, and management of hypertension and/or diabetes Low- and middle-income countries and/or vulnerable populations in high income countries Identify best evidence-based interventions implementation and scale-up according commitments at regional or national level Address the comorbidities! Cost-effectiveness All stakeholders involved at all stages (including proposal design) Gender and cultural aspects RIA : 2-4M : : 5-10 projets

16 Call 1 Better health and care, economic growth and sustainable health SC1-BHC : Translational collaborative cancer research between Europe and the Community of Latin American and Caribbean States (CELAC) Translational and multidisciplinary research to identify specific patient groups in view of improving one or more of the following aspects: screening, early detection, diagnosis and/or prognosis. Build on the diverse genetic backgrounds, risk factors, cancer incidence, geographical environment, and/or different healthcare models in European and CELAC countries Molecular, behavioural, nutritional, clinical, social and environmental epidemiology Use data from cohorts, biobanks, repositories, research infrastructures Two participants from two different CELAC countries RIA : 2-4M : : 6-12 projets

17 Call 1 Better health and care, economic growth and sustainable health SC1-BHC : Research on HIV, tuberculosis (TB) and/or hepatitis C (HCV) in patients with mono-, co-infections and/or comorbidities in the context of fostering collaboration with the Russian Federation Understand and address current epidemiological situation issues to reduce the cases of new infections and deaths, particularly in vulnerable groups (ageing, drug users ) TB: biomarkers or new diagnostics tests for early screening of TB risk groups and identification of antimicrobial drug resistance HIV: susceptibility to HIV and/or disease progression rate HCV: genetic determinants of the virus and the host, and comorbid conditions Already established European cohort networks + NEW Sex & gender At least one partner from the Russian Federation RIA : 2-3M : (max. 24 months) : 3-5 projets

18 Call 1 Better health and care, economic growth and sustainable health SC1-HCO : Establishment of an International Network of Social Sciences Research Centres to help address governance and other challenges in the preparedness for and the response to infectious threats Establish an International Network of Social Sciences Research Centres, to better address governance and other challenges in prevention and response to infectious threats, be it at local, national, regional or global levels be better prepared to respond to infectious threats. Initiate the INSSR addressing governance challenges Engage with stakeholders and research funding agencies at an international scale Establish the central coordinating hub for the network Maximise opportunities for collaboration, learning and data sharing Collaboration with existing initiatives CSA : 2-3M : : 1 projet

19 Call 1 Better health and care, economic growth and sustainable health SC1-HCO : Building international efforts on population and patient cohorts Establish a strategy for the development of the next generation of integrated cohorts Build on existing cohorts Map the cohort landscape in EU and large international initiatives Identify best strategies for integration Define an international strategic agenda for better coordination of cohorts globally Data collection harmonisation and management Foster the inclusion of data emerging from new technologies and new type of data Access to cohorts CSA : 1-2M : : 1-2 projets

20 Call 1 Better health and care, economic growth and sustainable health SC1-HCO : Coordinating European brain research and developing global initiatives Enhance networking and coordination efforts between the different brain research initiatives, at both European and global level, in order to minimise fragmentation and duplication as well as facilitate access to data to enhance the exploitation of results. Identify areas of neurosciences which particularly need enhanced coordination of research communities Accelerate exchange between researchers Facilitate links with research infrastructures and other major initiatives (including European Commission services) Explore possibilities for broader scale cooperation (outside Europe) CSA : 1-2M : : 1-2projets

21 Call 1 Better health and care, economic growth and sustainable health SC1-HCO : Strategic collaboration in health research and innovation between EU and China Support networking between European and Chinese policy makers, programme owners and funders. Develop a sustainable platform facilitating a constant dialogue on addressing common health R&I challenges Identify health challenges, whose solution may benefit from closer bi-lateral and/or multi-lateral cooperation between EU and China International cooperation CSA : 0,8-1M : : 1 projet

22 Call 1 Better health and care, economic growth and sustainable health SC1-BHC : Novel patient-centred approaches for survivorship, palliation and/or end-of-life care Demonstrate the effectiveness and cost-effectiveness of new, improved or specifically adapted pharmacological and/or non-pharmacological interventions to either relieve symptoms and suffering caused by life-threatening non-communicable diseases or serious late and long-term side effects of disease treatments in patients and survivors, or symptoms that occur at the end of life. Randomised clinical trials/observational studies Children and/or adults Prove the feasibility of integrating the proposed interventions in current palliative and/or end-oflife and/or survivorship care regimes and healthcare systems across Europe Sex, gender, age and socio-economic factors + any other factors affecting health equity RIA : 3-4M : : projet

23 Call 1 Better health and care, economic growth and sustainable health SC1-BHC : HTA research to support evidence-based healthcare Proposals should develop new or improved methodological approaches and frameworks, and foster methodological consensus-building to address all the following: Specific types or groups of health technologies Selected therapeutic areas Use of real-world data Implementation Close liaise with EUnetHTA RIA : 5-10M : : 1-2 projets

24 Call 1 Better health and care, economic growth and sustainable health SC1-BHC : New testing and screening methods to identify endocrine disrupting chemicals New and improved approaches are needed to increase the quality and efficiency of existing methods to meet demanding and evolving regulatory requirements worldwide Improve and harmonise screening and testing protocols/strategies and hazard/risk assessments Better and faster tools, methods or models, including high-throughput and in silico methods Research on adverse outcomes pathways to human health (in vitro) Epidemiological and field monitoring data Focus on most urgent regulatory needs: thyroid axis, developmental neurotoxicity, metabolic disorders, female reproduction and non-genotoxic carcinogenicity Involvement of regulatory bodies + JRC International cooperation (OECD, EU ) RIA : 4-6M : : 8-12 projets

25 Call 1 Better health and care, economic growth and sustainable health SC1-HCO : Setting the priorities for a European environment, climate and health research agenda Establish a research/policy coordination group (science and policy actors in environment and health from H2020-funded activities; national/eu regulatory bodies; international actors) Identify key policy areas requiring scientific support for environment, climate change and health related issues Develop a European medium-term research and innovation strategy and agenda Develop a set of guidelines reflecting current state-of-art for health impact and risk assessment of environmental factors applicable across key sectors Engagement of all stakeholders internationally Clear work plan for 3 years CSA : 2-3M (3 years project) : : 1 projet

26 Budget # projets financés Deadline SC1 BHC : Understanding causative mechanisms in co- and multimorbidities SC1-BHC : Systems approaches for the discovery of combinatorial therapies for complex disorders RIA 4-6M 5 RIA 4-6M SC1-HCO : Actions in support of the International Consortium for Personalised Medicine International aspects: China Standardisation for clinical studies design SC1-BHC : Regenerative medicine: from new insights to new applications SC1-BHC : Innovation Procurement: Next generation sequencing (NGS) for routine diagnosis SC1-BHC : Stratified host-directed approaches to improve prevention, treatment and/or cure of infectious diseases CSA 1,5-2M RIA 6-8M PCP 9-11M RIA 6-10M 9-15 SC1-BHC : Implementation research for maternal and child health RIA 2-4M 5-10 SC1-HCO : Creation of a European wide sustainable clinical research network for infectious diseases CSA 2-3M

27 Budget # projets financés SC1-BHC : Mental health in the workplace RIA 2-4M 7-15 Deadline SC1-BHC : Demonstration pilots for implementation of personalised medicine in healthcare IA 18-20M SC1-BHC : The Human Exposome Project: a toolbox for assessing and addressing the impact of environment on health RIA 8-12M

28 Crosscutting activities

29 Call 1 Better health and care, economic growth and sustainable health SC1-NMBP : Osteo-articular tissues regeneration Conceive innovative designs and development of innovative user-centred biomaterials enabling the delivery of smart, nanostructured and functionalised tissues for personalised regeneration of bones, cartilages, tendons and joints. Smart and innovative nanobiomaterials also adaptable to remote control Materials will perform in host tissues affected by severe inflammatory processes Technologies: 3D-bioprinting, Stem cells technologies, nanofunctionalisation, 3Dprintable biophotopolymeration, additive manufacturing, electrospinning, cross-cutting KETs SSH & user involvement Cooperation with other projects + accessibility and reusability of data RIA : 4-6M : début 2018? : 4-6 projets

30 NMBP : Custom-made biological scaffolds for specific tissue regeneration and repair Budget # projets financés Deadline RIA??? DT-NMBP : Next generation organ-on-chip (RIA) RIA???

31 Crosscutting activities

32 Call 1 Better health and care, economic growth and sustainable health DT-SFS : Personalised nutrition Deliver innovative solutions (concepts/tools/products/services) for personalised nutrition advice and/or support that will help consumer to achieve their optimal health and well-being and to adopt long-term healthy and sustainable diets. Understanding food choice and environment Focus on the consumer benefits Integrate all relevant factors (health indicators, nutritional requirements, food composition, lifestyle, preferences, environment, socio-economic ) Innovative health and care systems Integration of care New, smart digital/ict applications for all levels of personalization Limited research, prototyping, testing, demonstrating, piloting and large-scale products validation Consumer engagement and acceptance Ethics, regulatory aspects RIA : 7M : : 4 projets

33 A vous de jouer

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36 - 36 -

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39 Fin Merci pour votre attention Vos contacts au NCP-Wallonie : Emilie ETOUNDI European Project Developer Horizon 2020 Health, Biotechnology, Agriculture & Food NCP Tél : +32 (0) emilie.etoundi@ncpwallonie.be Pierre Fiasse (NMBP) European Project Developer Horizon 2020 Nano, Materials, Transport & Aero NCP Tél: +32 (0) pierre.fiasse@ncpwallonie.be