The role of PHE s AMRHAI Reference Unit
|
|
- Ella Little
- 6 years ago
- Views:
Transcription
1 The role of PHE s AMRHAI Reference Unit Professor Neil Woodford Antimicrobial Resistance & Healthcare Associated Infections (AMRHAI) Reference Unit Crown copyright
2 What does AMRHAI offer? Susceptibility testing for confirmation of exceptional resistances Infer resistance mechanisms from antibiograms Investigation of priority resistance mechanisms Strain typing to aid outbreak investigation Treatment advice; infection prevention & control advice + Research (externally-funded) + Evaluations of new drugs and diagnostics (externally-funded) 2 UK-Russia (Moscow), 18th December 2015 Crown Copyright
3 My Unit s goals Setting England s (the UK s) Resistance and HCAI Problems into National and Global Context Better understanding of (resistant) bacterial clones distribution (global, national, regional) contribution resistance plays to success Coordinated surveillance of mechanisms global, regional and national Identify geographic hot spots and high risk patients early, targeted IPC interventions 3 UK-Russia (Moscow), 18th December 2015 Crown Copyright
4 Feed into the UK s integrated surveillance of AMR risks Colonized residents or visitors Non-human reservoirs: foodstuffs (domestic or imported) Non-human reservoirs: animals and environment Hospital treatment or travel overseas Inter-hospital transfers (UK) Victims from conflict zones Multiple risks to be assessed to minimize damage We need better intelligence 4 UK-Russia (Moscow), 18th December 2015 Crown Copyright
5 AMRHAI works with PHE s surveillance scientists Pathogen % carbapenem resistance E. coli K. pneumoniae Provides specialist microbiology that seeks to explain trends Is at the centre of a national / regional laboratory network Benefits from a spider s web effect Monitors new and emerging AMR issues, long before they register in surveillance programmes 5 UK-Russia (Moscow), 18th December 2015 Crown Copyright Data, courtesy Prof Alan Johnson
6 CPE in the UK, Imported & home grown Early cases often imported Klebsiella spp. 79%; E. coli 12%, Enterobacter spp., 7%; others 2% 6 UK-Russia (Moscow), 18th December 2015 Crown Copyright AMRHAI, Unpublished data
7 Towards WGS for reference services Define lineage & surveillance Predict resistance Biomarkers ID + Outbreak investigations Phase 2 WGS Assess virulence 7 UK-Russia (Moscow), 18th December 2015 Crown Copyright
8 WGS-based genotypic antibiograms could soon replace much AST for surveillance purposes low impact of the low error rate could soon reduce need for AST in reference laboratories unless to guide treatment for agents with poorest genotypic/phenotypic concordance comparative in-vitro activity of new agents EUCAST Subcommittee on the role of whole genome sequencing (WGS) in antimicrobial susceptibility testing of bacteria Chair: Neil Woodford, London UK; will report in mid UK-Russia (Moscow), 18th December 2015 Crown Copyright
9 Working with academia Health Protection Research Units in HCAI and AMR Imperial College and PHE (Alison Holmes and Alan Johnson) University of Oxford and PHE (Derrick Crook and Neil Woodford) National research units involving a network of relevant, world class expertise that can comprehensively address the challenges of AMR and HCAI, with the resilience and capacity to respond to emerging issues and public health priorities Creating integrated programmes of research to develop new, cost-effective approaches for detection, surveillance, investigation and reduction of HCAI and AMR in the NHS 9 UK-Russia (Moscow), 18th December 2015 Crown Copyright
10 Working with industry extensive collections of MDR clinical isolates Active vs. >90% UK CPE independent evaluations of: diagnostics AST platforms developmental antibiotics Possible No 2 0 Approved Phase 3 Phase 2 Phase 1 10 UK-Russia (Moscow), 18th December 2015 Crown Copyright
11 AMRHAI is a WHO Collaborating Centre Participate in missions and training courses AMR and/or IPC Promote reference microbiology for AMR Reference testing and characterisation of isolates received Supply control isolates Promote research/development in reference laboratories Host overseas visitors on short or long-term placements Support applications for funding Seek funding for WHO CC activities Lobbying Groundwork for bids to The Fleming Fund in UK-Russia (Moscow), 18th December 2015 Crown Copyright
12 Improving interaction with other AMR CCs CAESAR Network one-year FTC post (lab-based) secured from PHE s AMR Priority Programme Delivery Board, to support projects Seek close working with CCs at RIVM and in Smolensk bid to Gates Foundation (Karolinska / PHE / RIVM) WHO-Net close working with CC in Boston; named collaborators on bid to NIH develop the software to increase capacity for handling molecular and WGSderived data 12 UK-Russia (Moscow), 18th December 2015 Crown Copyright
13 National & international capacity building Without lab testing we re blind to (the extent of) AMR problems Improve lab access; aim for a reference lab in every country / region Each serving as the hub of a national network Each acting as a spoke in an international network Performing essential techniques, proficient to international standards Sharing data / experience 13 UK-Russia (Moscow), 18th December 2015 Crown Copyright
Can whole genome sequencing replace AST?
Can whole genome sequencing replace AST? Matthew J Ellington Antimicrobial Resistance & Healthcare Associated Infections (AMRHAI) Reference Unit Crown copyright EUCAST Subcommittee on the role of whole
More informationCombatting AMR: diagnostics
Combatting AMR: diagnostics Professor Neil Woodford Antimicrobial Resistance & Healthcare Associated Infections (AMRHAI) Reference Unit Crown copyright Gonorrhoea: a paradigm for better diagnostics International
More informationEnabling the adoption of new diagnostics within the UK healthcare system:
Enabling the adoption of new diagnostics within the UK healthcare system: The key role of diagnostics in the AMR challenge Fiona Carragher FRCPath @DepCSOFiona Deputy Chief Scientific Officer for England
More informationUK AMR Diagnostics Collaborative:
UK AMR Diagnostics Collaborative: Maximising the use of diagnostic technology to tackle AMR Fiona Carragher FRCPath @DepCSOFiona Deputy Chief Scientific Officer for England england.amrdiagnostics@nhs.net
More informationFunding AMR research: the UK Research Councils John Savill
Funding AMR research: the UK Research Councils John Savill Medical Research Council - UK MRC mission Encourage and support high-quality research with the aim of improving human health. Produce skilled
More informationScottish Microbiology & Virology Network (SMVN)
Scottish Microbiology & Virology Network (SMVN) Annual Workplan 2017-2018 Version 1.0 26 May 2017 Page 1 of 10 SMVN HIGH PRIORITY OVERVIEW The highest priority activities of the SMVN are summarised below.
More informationOverview of EURL-AMR and NGS activities
Overview of EURL-AMR and NGS activities Lina Cavaco licav@food.dtu.dk 1 DTU Food, Technical University of Denmark Outline EURL-AR presentation and tasks EU activities Ring trials for E. coli in EURL-AR
More informationCORPORATE PRESENTATION
CORPORATE PRESENTATION March 2018 1 Forward Looking Statement This presentation includes statements relating to the company's Acuitas MDRO and Acuitas Lighthouse clinical laboratory services, FDA cleared
More informationMoving towards delivering precision medicine in sepsis
Moving towards delivering precision medicine in sepsis Paul Dark Professor of Critical Care Medicine, Division of Infection and Immunity, University of Manchester NIHR CRN National Specialty Lead (Critical
More information2014 APHL Next Generation Sequencing (NGS) Survey
APHL would like you to complete the Next Generation Sequencing (NGS) in Public Health Laboratories Survey. The purpose of this survey is to collect information on current capacities for NGS testing and
More informationIntroduction to Whole Genome Sequencing and its Applications in Microbial Diagnostics
Introduction to Whole Genome Sequencing and its Applications in Microbial Diagnostics Workshop on Whole Genome Sequencing and Analysis, 19-21 Mar. 2018 Whole genome sequencing is currently revolutionising
More informationThe interplay between AMR surveillance and science Report of JPIAMR workshop October 2016, The Research Council of Norway, Oslo, Norway
The interplay between AMR surveillance and science Report of JPIAMR workshop 12.-13. October 2016, The Research Council of Norway, Oslo, Norway Table of contents List of participants... 1 Abbreviations...
More informationNDA Requirements: Surveillance, Clinical Trial Data, Breakpoints
NDA Requirements: Surveillance, Clinical Trial Data, Breakpoints Kevin M. Krause Director Microbiology Achaogen, Inc. Presented at the ASM/ESCMID Conference on Drug Development to Meet the Challenge of
More informationForecast diagnostics for antimicrobial resistance (AMR)
Forecast diagnostics for antimicrobial resistance (AMR) Authors: Ann Van den Bruel, Philip Turner NIHR Diagnostic Evidence Cooperative Oxford, University of Oxford Context When asked to make forecasts
More informationTBResist: A Global Consortium for Whole Genome Sequencing of Drug Resistant TB. IOM/IMCAS Meeting Beijing January 16-18, 2013
TBResist: A Global Consortium for Whole Genome Sequencing of Drug Resistant TB IOM/IMCAS Meeting Beijing January 16-18, 2013 Past and Future of TB Research I. Comas and S. Gagneux PLoS Pathog. 2009 October:
More informationMicrobiology of Healthcare-associated Infections
Microbiology of Healthcare-associated Infections William A. Rutala, Ph.D., M.P.H. Director, Statewide Program for Infection Control and Epidemiology and Professor of Medicine, University of North Carolina
More informationPathogenic bacteria replicate and persevere in ecological niches called reservoirs
TYPING METHODS WHAT IS TYPING AND WHAT ARE TYPING METHODS? Pathogenic bacteria replicate and persevere in ecological niches called reservoirs Reservoirs may be humans, including (fellow) patients and healthcare
More informationWhole Genome Sequencing for Enteric Pathogen Surveillance and Outbreak Investigations
Whole Genome Sequencing for Enteric Pathogen Surveillance and Outbreak Investigations Anne Maki, Manager, Enteric, Environmental, Molecular Surveillance and Bacterial Sexually Transmitted Infections, Public
More informationCONDUCTING AND EVALUATING
CONDUCTING AND EVALUATING ANTIBIOTIC STEWARDSHIP: COMMERCIAL PRODUCTS VERSUS DIY Jessina C. McGregor, PhD Dept. Pharmacy Practice College of Pharmacy Oregon State University/Oregon Health & Science University
More informationIntroduction to Whole Genome Sequencing and its Applications in Microbial Diagnostics
Introduction to Whole Genome Sequencing and its Applications in Microbial Diagnostics Workshop on Whole Genome Sequencing and Analysis, 27-29 Mar. 2017 Whole genome sequencing is currently revolutionising
More informationEnvironmental Surveillance FIDSSA Dr Ben Prinsloo Medical Microbiologist
Environmental Surveillance FIDSSA 2015 Dr Ben Prinsloo Medical Microbiologist The Scientist A scientist, in a broad sense, is a person engaging in a systematic activity to acquire knowledge We require
More informationCHAPTER 24. Immunology
CHAPTER 24 Diagnostic i Microbiology and Immunology Growth-Dependent Diagnostic Methods Isolation of Pathogens from Clinical Specimens Proper sampling and culture of a suspected pathogen is the most reliable
More informationMolecular Diagnostics
Molecular Diagnostics Part II: Regulations, Markets & Companies By Prof. K. K. Jain MD, FRACS, FFPM Jain PharmaBiotech Basel, Switzerland May 2018 A Jain PharmaBiotech Report A U T H O R ' S B I O G R
More informationGenomics and its Impact on Diagnostic Microbiology
Genomics and its Impact on Diagnostic Microbiology Rick Holliman Lead Public Health Microbiologist for London Outline Where are we now? What is coming our way? How will things change? Where will we be?
More informationMicrofluidics as an enabler for Medical Diagnostics
Microfluidics as an enabler for Medical Diagnostics Henne van Heeren, enablingmnt Microfluidics: The ability to create complex channel manifolds on a single substrate with no dead volume between connecting
More informationThe 100,000 Genomes Project Genomics Collaboration Event Finnish Residence
The 100,000 Genomes Project Genomics Collaboration Event Finnish Residence Prof Mark Caulfield FMedSci Chief Scientist for Genomics England Barts Heart Centre William Harvey Research Institute Queen Mary
More informationQuality Control and Quality Assurance for Antibiotic Testing
Quality assurance Quality Control and Quality Assurance for Antibiotic Testing 26 Sep 2013 Microbiology Technical Workshop Lily Ng Siew Yong practice of assessing performance in all steps of the process
More informationDisruptive Technology to Guide Precision Antibiotic Therapy
Disruptive Technology to Guide Precision Antibiotic Therapy Company Presentation, October 2018 Forward Looking Statement This presentation includes statements relating to the company's Acuitas AMR Gene
More informationChallenges and opportunities for whole genome sequencing based surveillance of antibiotic resistance
Challenges and opportunities for whole genome sequencing based surveillance of antibiotic resistance Prof. Willem van Schaik Professor in Microbiology and Infection Institute of Microbiology and Infection
More informationDiagnostics gathering intelligence to fight antimicrobial resistance
Diagnostics gathering intelligence to fight antimicrobial resistance Arjon van Hengel European Commission DG Research and Innovation, Health Directorate Unit "Fighting Infectious Diseases and Advancing
More informationBeef Industry Safety Summit Renaissance Austin Hotel 9721 Arboretum Blvd. Austin, TX March 1-3
1 USDA, Food Safety and Inspection Service Beef Industry Safety Summit - 2016 Renaissance Austin Hotel 9721 Arboretum Blvd. Austin, TX 78759 March 1-3 Uday Dessai MPH, MS, PhD Senior Public Health Advisor
More informationWhole Genome Sequencing for food safety FSA Chief Scientific Advisor Report and 2013 Listeria pilot study
Whole Genome Sequencing for food safety FSA Chief Scientific Advisor Report and 2013 Listeria pilot study Dr Edward Hayes Date: July 2016, Version 1 Foodborne Pathogens 280,000 cases of Campylobacter,
More informationWorking at Colindale, national and international projects, organisation. Pam Saunders
Working at Colindale, national and international projects, organisation. Pam Saunders Public Health England Public Health England (PHE) is an executive agency of the Department of Health that began operating
More informationNEXT STEP TO STOP THE SPREAD OF ANTIMICROBIAL RESISTANCE. Patricia Ruiz Garbajosa Servicio de Microbiología Hospital Universitario Ramón y Cajal
NEXT STEP TO STOP THE SPREAD OF ANTIMICROBIAL RESISTANCE Patricia Ruiz Garbajosa Servicio de Microbiología Hospital Universitario Ramón y Cajal ANTIMICROBIAL RESISTANCE AND HEALTHCARE-ASSOCIATED INFECTION
More informationNEW DRUG FORMULATIONS TO BOOST FIGHT AGAINST RESPIRATORY ILLNESSES AND ANTIBIOTIC-RESISTANT SUPERBUGS
MEDIA RELEASE FOR IMMEDIATE RELEASE 15 September 2014 NEW DRUG FORMULATIONS TO BOOST FIGHT AGAINST RESPIRATORY ILLNESSES AND ANTIBIOTIC-RESISTANT SUPERBUGS A team from A*STAR s Institute of Chemical and
More informationIntroduction to Whole Genome Sequencing and its Applications in Microbial Diagnostics
Introduction to Whole Genome Sequencing and its Applications in Microbial Diagnostics Workshop on Whole Genome Sequencing and Analysis, 2-4 Oct. 2017 Whole genome sequencing is currently revolutionising
More informationPERANAN MIKROBIOLOGI DALAM DIAGNOSIS PENYAKIT INFEKSI. dr. Agus Eka Darwinata, Ph.D.
PERANAN MIKROBIOLOGI DALAM DIAGNOSIS PENYAKIT INFEKSI dr. Agus Eka Darwinata, Ph.D. CLINICAL MICROBIOLOGY Clinical microbiology is the discipline of detection, characterization, and quantification of
More informationEducational Workshops 2016
Educational Workshops 2016 Case One: Outbreak of CPE We are grateful to Suzy Fitzgerald, Consultant Microbiologist, St Vincent s University Hospital, Dublin for composing this case. 2011 Spring 2011 Sporadic
More informationCarbapenem-resistant Enterobacteriaceae (CRE): Surveillance and Response. David Selvage, MHS, PA-C New Mexico Department of Health March 15, 2016
Carbapenem-resistant Enterobacteriaceae (CRE): Surveillance and Response David Selvage, MHS, PA-C New Mexico Department of Health March 15, 2016 What are Carbapenem-resistant Enterobacteriaceae (CRE)?
More informationFrom classical molecular typing to WGS in a food safety context: WGS at EFSA
From classical molecular typing to WGS in a food safety context: WGS at EFSA Beatriz Guerra EURL-AR WGS Training, Copenhage, Denmark, 27.09.17 WGS FOR FOOD SAFETY AT EFSA Molecular Typing Recent Past:
More informationFORWARD LOOKING STATEMENTS
Jefferies 2014 Healthcare Conference November 19, 2014 FORWARD LOOKING STATEMENTS This presentation contains forward looking statements. Any statements contained herein which do not describe historical
More informationThe implementation and application of Whole Genome Sequencing in the Campylobacter Reference Laboratory at Public Health England Craig Swift
The implementation and application of Whole Genome Sequencing in the Campylobacter Reference Laboratory at Public Health England Craig Swift Campylobacter EURL workshop (2018) The Gastrointestinal Bacteria
More informationENABLE (IMI) presentation of activities
ENABLE (IMI) presentation of activities A European antibacterial drug discovery platform Anders Karlén Uppsala University (SE) New Drugs for Bad Bugs (ND4BB) Structure ND4BB Co-ordination team (science
More informationGUIDANCE FOR INTERPRETATION OF PCR ASSAYS FOR VEROCYTOTOXIGENIC
GUIDANCE FOR INTERPRETATION OF PCR ASSAYS FOR VEROCYTOTOXIGENIC E COLI: FOR HEALTH PROTECTION TEAMS AND MICROBIOLOGISTS 1. Purpose of this document The purpose of this document is to provide broad recommendations
More informationMASTER PROTOCOLS IN COLLABORATIVE RESEARCH
MASTER PROTOCOLS IN COLLABORATIVE RESEARCH Lisa LaVange, PhD Professor and Associate Chair ASA Biopharmaceutical Section/ Industry/Regulatory Workshop Washington, DC September 13-14, 2018 Outline Precision
More informationInvestigational New Drug - Groundwork for in vitro antimicrobial susceptibility testing
Investigational New Drug - Groundwork for in vitro antimicrobial susceptibility testing Erika Matuschek, Ph D Lead Scientist/Operational Manager EUCAST Development Laboratory (EDL) Växjö, Sweden ASM/ESCMID
More informationAntimicrobial Resistance Prediction Using Deep Convolutional Neural Networks on Whole Genome Sequencing Data
Antimicrobial Resistance Prediction Using Deep Convolutional Neural Networks on Whole Genome Sequencing Data PRIMES Research Report by: Andrew Zhang Mentor: Dr. Gil Alterovitz PRIMES Conference October
More informationComparative genomics of clinical isolates of Pseudomonas fluorescens, including the discovery of a novel disease-associated subclade.
Comparative genomics of clinical isolates of Pseudomonas fluorescens, including the discovery of a novel disease-associated subclade. by Brittan Starr Scales A dissertation submitted in partial fulfillment
More informationCARBAPENEM-RESISTANT ENTEROBACTERIACEAE (CRE) LABORATORY CAPACITY SURVEY. Summary Data Report
CARBAPENEM-RESISTANT ENTEROBACTERIACEAE (CRE) LABORATORY CAPACITY SURVEY June 2015 Introduction The rise of antimicrobial-resistant organisms represents a serious threat to public health. In 2013, CDC
More informationWhole Genome Sequence Data Quality Control and Validation
Whole Genome Sequence Data Quality Control and Validation GoSeqIt ApS / Ved Klædebo 9 / 2970 Hørsholm VAT No. DK37842524 / Phone +45 26 97 90 82 / Web: www.goseqit.com / mail: mail@goseqit.com Table of
More informationCDC Antibiotic Resistance Laboratory Network- Southeast Region. Nailah Smith, DVM, MPH, Epidemiologist
CDC Antibiotic Resistance Laboratory Network- Southeast Region Nailah Smith, DVM, MPH, Epidemiologist Overview ARLN Introduction Southeast Regional Laboratory Overview ARLN Alert Values Isolate flow CRE
More informationThe Innovative Medicines Initiative Europe s partnership for health. Tek-Ang LIM, 20 June 2018, Brussels
The Innovative Medicines Initiative Europe s partnership for health Tek-Ang LIM, 20 June 2018, Brussels 10 YEARS OF LIGHTING THE WAY IMI Why Europe s partnership for health? Because despite decades of
More informationResponses to the Antimicrobial Resistance Threat A comparative study of selected national strategies and policies
Responses to the Antimicrobial Resistance Threat A comparative study of selected national strategies and policies PAC 11 side-event From strategies to action Addressing the challenges of AMR in the Northern
More informationCall Details. Introduction of DBT-BIRAC Joint call:
Call Details Antimicrobial resistance (AMR) is one of the major threats to human health in the 21 st century, with some bacterial pathogens acquiring resistance to all clinically available antibiotics.
More informationCDRH: Advancing Regulatory Science. Murray Malin, MD Center for Devices and Radiological Health March 29, 2011
CDRH: Advancing Regulatory Science Murray Malin, MD Center for Devices and Radiological Health March 29, 2011 Medical Countermeasures Diagnostic and Detection Devices Personal Protective Equipment (PPE)
More informationEvolution of Next Generation Sequencing Technology: Ready for Patient Management?
Evolution of Next Generation Sequencing Technology: Ready for Patient Management? Timothy Rodwell MD, PhD, MPH Senior Scientific Officer at FIND 3 rd December 2015, Union Meeting Cape Town Clinical Utility
More informationThe Antimicrobial Resistance Laboratory Network (ARLN) Providing CRE Colonization Testing to a State Lab in a Neighboring Region June 4, 2018
The Antimicrobial Resistance Laboratory Network (ARLN) Providing CRE Colonization Testing to a State Lab in a Neighboring Region June 4, 2018 Kimberlee Musser, PhD Chief of Bacterial Disease Northeast
More informationConcept Note High Level Meeting on Multi-Sectoral Action Plan to Combat Antimicrobial Resistance in Cambodia
1. Background Concept Note High Level Meeting on Multi-Sectoral Action Plan to Combat Antimicrobial Resistance in Cambodia 29-30 November 2017 in Raffles Le Royal Hotel, Phnom Penh, Cambodia The increasing
More informationDelivering the NIHR Central Commissioning Facility
Delivering the NIHR Central Commissioning Facility About the NIHR The National Institute for Health Research is funded through the Department of Health to improve the health and wealth of the nation through
More informationCRE is not the first organism we ve had that has become resistant to antibiotics, so why is it so important? CRE resistance is complex because it can
1 Enterobacteriaceae are a large family of bacteria that are a normal part of a person's digestive system (2). Examples include Escherichia coli and species of the genera Klebsiella, Enterobacter, Serratia,
More informationHow can measurement science assist in improving AMR diagnostics research and development?
How can measurement science assist in improving AMR diagnostics research and development? Jim Huggett Principal Scientist, Nucleic Acid Research Molecular & Cell Biology, LGC Senior Lecturer, Analytical
More informationCloning and Characterization of E. meningoseptica Beta Lactamase
Cloning and Characterization of E. meningoseptica Beta Lactamase Authors: Lindsey Purcell, Jessica Matts, Patricia Canaan* Department of Biochemistry and Molecular Biology Abstract Elizabethkingia meningoseptica
More informationEnvironmental spread of antimicrobial resistance: Bangladesh perspective
Environmental spread of antimicrobial resistance: Bangladesh perspective Mohammad Aminul Islam, PhD Associate Scientist & Head Enteric and Food Microbiology Laboratory icddr,b, Bangladesh Workshop on National
More informationNIHR Invention for Innovation Workshop. Leeds Clinical Research Facility Adding Value Debbie Beirne NIHR Leeds CRF Manager
NIHR Invention for Innovation Workshop Leeds Clinical Research Facility Adding Value Debbie Beirne NIHR Leeds CRF Manager Integrated R&I Model Surgical MedTech (MIC) CRF R&I In Vitro Diagnostics (MIC)
More informationUK Standards for Microbiology Investigations
UK Standards for Microbiology Investigations Potassium Hydroxide Test Issued by the Standards Unit, Microbiology Services, PHE Bacteriology Test Procedures TP 30 Issue no: 2.2 Issue date: 14.03.14 Page:
More informationThe Cat s Out of the Bag: Microbiological Investigations of Acute Transfusion Reactions.
The Cat s Out of the Bag: Microbiological Investigations of Acute Transfusion Reactions. Philippe Lagacé-Wiens, MD FRCPC, DTM&H plagacewiens@sharedhealthmb.ca COI declaration I have no conflicts, real
More informationIFSH WHOLE GENOME SEQUENCING FOR FOOD INDUSTRY SYMPOSIUM May 22-23, 2017
1 USDA, Food Safety and Inspection Service IFSH WHOLE GENOME SEQUENCING FOR FOOD INDUSTRY SYMPOSIUM May 22-23, 2017 Chicago Marriott Southwest at Burr Ridge 1200 Burr Ridge Parkway, Burr Ridge, IL 60527
More informationHCAI Data Capture System User Manual. Counts or Rates of Infection Episodes Report
User Manual Counts or Rates of Infection Episodes Report About Public Health England Public Health England exists to protect and improve the nation's health and wellbeing, and reduce health inequalities.
More informationRapid Diagnostic Tests for Antimicrobial Resistance: Comparability of Results and Interpretation of Data
Rapid Diagnostic Tests for Antimicrobial Resistance: Comparability of Results and Interpretation of Data Christopher Teale, Animal and Plant Health Agency, UK. 12 th OIE One-Day Seminar, in association
More informationLEGIONELLA MONITORING AND RISK ASSESSMENTS
LEGIONELLA MONITORING AND RISK ASSESSMENTS Sampling Plans, Results and Remediation Janet E. Stout, PhD Director, Special Pathogens Laboratory Research Associate Professor University of Pittsburgh Objectives
More informationAntibiotics to Treat Multidrug-Resistant Bacterial Infections
Antibiotics to Treat Multidrug-Resistant Bacterial Infections Copyright 2017 Tetraphase Pharmaceuticals, Inc. C O M P A N Y P R E S E N T A T I O N A p r i l 2 0 1 7 TTPH Forward-Looking Statements and
More informationCurriculum Vitae. Abbas Maleki, Ph.D. Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran
Curriculum Vitae Abbas Maleki, Ph.D Clinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran E-mail: abbasmaleki_ilam@yahoo.com maleki-a@medilam.ac.ir Tel: +989187419401 Personal
More informationGMI: Global Microbial Identifier
GMI: Global Microbial Identifier The future of microbiology: Identification and Surveillance will merge through the use of Whole Genome Sequencing (WGS) Jørgen Schlundt Professor Technical University of
More informationSusceptibility of extended-spectrum- β-lactamaseproducing Escherichia coli to commercially available and laboratory-isolated bacteriophages.
Royal College of Surgeons in Ireland e-publications@rcsi Clinical Microbiology Articles Department of Clinical Microbiology 1-4-2014 Susceptibility of extended-spectrum- β-lactamaseproducing Escherichia
More informationProvisional Strategic Research Agenda for the One Health European Joint Programme. Date: 14 February 2017
Provisional Strategic Research Agenda for the One Health European Joint Programme Date: 14 February 2017 Colophon Authors: J.H. Bongers and A.W van de Giessen in collaboration with the One Health EJP consortium
More informationOverview of CIDT Challenges and Opportunities
Overview of CIDT Challenges and Opportunities Peter Gerner-Smidt, MD, DSc Enteric Diseases Laboratory Branch InFORM II Phoenix, AZ, 19 November 2015 National Center for Emerging and Zoonotic Infectious
More informationCRE Laboratory Testing and CRE Lab Testing Recommendations in-depth recommendations on CRE laboratory detection
December 2014 Dear Laboratory Director, The Illinois Department of Public Health (IDPH) amended the Control of Communicable Diseases Code (77 Ill. Adm. Code 690) to require reporting of Carbapenem-Resistant
More informationLeveraging Partnerships and Advanced Molecular Detection in Healthcare Environmental Investigations
Leveraging Partnerships and Advanced Molecular Detection in Healthcare Environmental Investigations Allison Perry, MS Sequencing Lead Clinical and Environmental Microbiology Branch Division of Healthcare
More informationVerification of Gradient Diffusion Strips
Verification of Gradient Diffusion Strips Objectives 1. Describe gradient diffusion tests 2. Describe process of FDA clearance of susceptibility tests 3. Discuss CLIA requirements for laboratory verification
More informationND4BB Topic 3: Discovery and development of new drugs combatting Gram-negative infections
ND4BB Topic 3: Discovery and development of new drugs combatting Gram-negative infections Rob Stavenger for EFPIA partners (AstraZeneca, Basilea, GlaxoSmithKline, & Sanofi) 17 December 2012 Antibiotic
More informationIDSA is pleased to offer the following comments on specific priority areas identified by FDA:
October 31, 2018 Shashi Malhotra Office of Acquisitions & Grants Services (OAGS) Food and Drug Administration Telephone: 240-402-7592 Email: Shashi.Malhotra@fda.hhs.gov SUBJECT: NOT-FD-18-16: Development
More informationPractical quality control for whole genome sequencing in clinical microbiology
Practical quality control for whole genome sequencing in clinical microbiology John WA Rossen, PhD, MMM Department of Medical Microbiology, University of Groningen, UMCG, Groningen, The Netherlands Disclosure
More informationBiosurveillance in a Global Age: Harnessing the Expertise of the Broad Scientific Community
UNCLASSIFIED//APPROVED FOR PUBLIC RELEASE Biosurveillance in a Global Age: Harnessing the Expertise of the Broad Scientific Community NDIA Biosurveillance Conference Dr. C. Nicole Rosenzweig US Army, Edgewood
More informationby author How to effectively report laboratory findings to clinicians (Breakpoints and Interpretation)
How to effectively report laboratory findings to clinicians (Breakpoints and Interpretation) A Vatopoulos National School of Public Health & Central Public Health Laboratory KEELPNO Antibiotic Activity
More informationGenomics in the NHS. Professor Sue Chief Scientific Officer for England
Genomics in the NHS Professor Sue Hill @CSOSue Chief Scientific Officer for England Nov 2017 100,000 Genomes Project: overview PRINCIPLES 100,000 genomes from Rare Disease (families) & Cancer (people &
More informationThe NHS approach to personalised medicine in respiratory disease. Professor Sue Chief Scientific Officer for England
The NHS approach to personalised medicine in respiratory disease Professor Sue Hill @CSOSue Chief Scientific Officer for England Jul 2017 Genomics is probably the biggest breakthrough in the last 50 years.
More informationCategory Guide NHS Supply Chain: Diagnostic, Pathology and Therapy Technologies, and Services
Category Guide NHS Supply Chain: Diagnostic, Pathology and Therapy Technologies, and Services Provided by Akeso & Company About the new NHS Supply Chain A new operating model NHS Supply Chain is implementing
More informationVerification of Disk Diffusion Tests
Verification of Disk Diffusion Tests Objectives 1. Describe disk diffusion tests 2. Describe process of FDA clearance of susceptibility tests 3. Discuss CLIA requirements for laboratory verification of
More informationEURL Working Group on NGS
EURL Working Group on NGS Rene S. Hendriksen, PhD Research group of Genomic Epidemiology National Food Institute, Technical University of Denmark Annual EURL AR workshop 5-6 April 2018 DTU, Kgs. Lyngby,
More informationTendering for Medicines and Services with CMU. Kevan Wind, Medicines Procurement Specialist Pharmacist, London & East of England
Tendering for Medicines and Services with CMU Kevan Wind, Medicines Procurement Specialist Pharmacist, London & East of England What we will cover 1. Pricing and Procurement of Medicines in the NHS. 2.
More informationCPTR title slide. Daniela M Cirillo San Raffaele Scientific Institute NDWG-Cochair
CPTR title slide Daniela M Cirillo San Raffaele Scientific Institute NDWG-Cochair Outline The global threat of Drug Resistant TB Actions to control MDR-TB Barriers to implement universal screening for
More informationM. Ben-David 1, O. Hammer 1, A.Scinderman 1, Y. Gluckman-Yavo 1, M. Fridman 1, D. Gohman 1, G. Ingber 1 and E. Zahavy 2
441 Rapid Gram Negative Antimicrobial Susceptibility Testing Directly from Positive Blood Culture based on a Unique Spectral Intensity Ratio Analysis via Single Fluorescence Membrane Dye Staining and Flow
More informationNEW DRUGS FOR BAD BUGS The Innovative Medicines Initiative response to antimicrobial resistance
NEW DRUGS FOR BAD BUGS The Innovative Medicines Initiative response to antimicrobial resistance Scan this QR code to download this booklet: IMI 2 Joint Undertaking, 2017 Photographs: Shutterstock, 2014
More informationgenerated by the usage of antimicrobial drugs is absent. She is the author of 14 publications in international journals.
Fernando Baquero Doctor in Medicine, Ramón y Cajal Research Professor in Bacterial Evolution at the Biomedical Research Foundation and Department of Microbiology of the Ramón y Cajal Universty Hospital.
More informationNext Generation Sequencing Applications in Food Safety and Quality
Next Generation Sequencing Applications in Food Safety and Quality Our science National and international centre of excellence for interdisciplinary investigation and problem solving across plant and bee
More informationJOB DESCRIPTION. The appointment is full time and will be for an initial 2 year period which could be extended.
JOB DESCRIPTION POST TITLE: REPORTING TO: GRADE: LOCATION: HOURS: Programme Lead Patient Safety Director of Programmes, Change & Performance Management tbc 10 Greycoat Place, London SW1 1SB 37.5 hours
More informationShionogi Presents Results of the First Clinical Efficacy Trial and In Vitro Data on Cefiderocol (S ), a Siderophore Cephalosporin
Shionogi Presents Results of the First Clinical Efficacy Trial and In Vitro Data on Cefiderocol (S-649266), a Siderophore Cephalosporin Osaka, Japan, April 22, 2017 - Shionogi & Co., Ltd. today announced
More informationHealth Data Research UK
Health Data Research UK Applicant pack Job description and person specification Post: Location: Salary: Digital Innovation Hub Project Manager London 50,000-70,000 dependent on experience Duration: Initial
More informationPrevention of Transmission of the Superbug Carbapenem-Resistant Enterobacteriaceae (CRE) during Gastrointestinal Endoscopy
Prevention of Transmission of the Superbug Carbapenem-Resistant Enterobacteriaceae (CRE) during Gastrointestinal Endoscopy Sponsored by: Presentation by: Lawrence F. Muscarella, Ph.D. President LFM Healthcare
More informationMed-tech and diagnostic device pathways in Newcastle
Med-tech and diagnostic device pathways in Newcastle Andrew Sims Medical Physics Newcastle upon Tyne Hospitals NHS Foundation Trust 12/07/2016 AHSN Stakeholder Engagement Meeting 1 Introduction Section
More information