Antiseptics and Disinfectants
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1 A BCC Research Chemical Report CHM052B Use this report to: Understand current and future characteristics of the global market for antiseptics and disinfectants Learn about various categories of antiseptics and disinfectants like biguanides and amidines, phenol and derivatives, iodine products, quaternary ammonium compounds, silver compounds, aldehydes, alcohols, oxidizing agents, and others Determine the techniques available to prevent any diseases with the use of antiseptics and disinfectants Identify major changes in market behavior, such as acquisitions, mergers, and alliances by companies and global organizations. T: , F:
2 Introduction The global market for antiseptics and disinfectants in 2009 was at about $3.4 billion, and with a 12% increase, sales reached about $3.8 billion in The market is expected to rise at a compound annual growth rate (CAGR) of 11.1% and reach $7.1 billion by An antiseptic is an antimicrobial substance that is applied to living tissue or skin to prevent infection, sepsis, or putrefaction. Where as an antimicrobial agent that is used to destroy microorganisms from the nonliving objects is known as a disinfectant. disinfectants are used to kill bacteria. They act very rapidly on contact. A distinction between antiseptics and disinfectants is made because disinfectants generally kill microorganisms or pathogens on nonliving objects, whereas antiseptics are used to kill bacteria on the skin of people or animals (living). Sometimes the same compound may act as an antiseptic or as a disinfectant. For example, hydrogen peroxide 6% solution is used as an antiseptic while solutions above 30% are used in industries as bleach and oxidizing agents. The purpose of the use of disinfectants is the same, to kill or inhibit the growth of infection-causing microorganisms; however, these are used on nonliving objects. These are used for bleaching, for surface disinfection, for dish washing, for toilet cleaning, for floor and wall cleaning in hospitals and clinics, in swimming pools to disinfect the water, to disinfect medical equipment, and in aircooling systems to disinfect the systems. Antiseptics are generally used to reduce levels of microorganisms on the skin and mucous membranes. A large number of harmless microorganisms are present on the skin and mucous membranes of the mouth, nose, and vagina. However, when the skin or mucous membranes are damaged or breached in surgery, antiseptics can be used to disinfect the area and reduce the chances of infection. Antiseptics are used for hand washing. Antiseptics are also used for mucous membrane disinfection. For this purpose, antiseptic irrigations may be instilled into the bladder, urethra, or vagina to treat infections or cleanse the cavity prior to catheterization. They are used for preventing and treating infected wounds and burns. These are also used to treat mouth and throat infection. Based on their chemical structures, antiseptics and disinfectants are classified into the following categories: Biguanides and amidines Phenol and derivatives Quaternary ammonium compounds Silver compounds Iodine products Alcohols Aldehydes Oxidizing agents Others This BCC Research report provides detailed information regarding antiseptics and disinfectants due to increasing awareness of consumers toward the inconspicuous dangers of microbes. The study looks at almost all types of products used at present and the new developments for antiseptics and disinfectants. This report will be of interest largely to the chemical, pharmaceutical, and biopharmaceutical industries; clinics; hospitals; and research institutes. The information for this report has been collected through both primary and secondary research methodologies. BCC conducted a comprehensive literature search, which included technical newsletters and journals, and many other sources. Data were collected through interviews and correspondence with various trade experts.
3 The United States constituted approximately 41% of the total antiseptics and disinfectants market in 2010 and was around $1.5 billion. The U.S. market is expected to increase to nearly $2.9 billion by 2016 at a CAGR of 11%. $ Millions 3,000 2,500 2,000 1,500 1, SUMMARY FIGURE WORLDWIDE REVENUE OF ANTISEPTICS AND DISINFECTANTS, ($ MILLIONS) U.S. Europe Rest of the World Source: BCC Research Scope of Study The scope of this report is broad and includes: Analysis of global antiseptics and disinfectants market trends, with data from 2010, estimates for 2011, and projections of compound annual growth rates (CAGRs) through 2016 Analysis of antiseptics and disinfectants markets by various types with its applications in different regions of the world A detailed analysis of the industry structure which includes all the categories of antiseptics and disinfectants, broken down by market shares belonging to leading suppliers An overview of the mechanism of action, and selection criteria, for antiseptics and disinfectants Suppliers profile of antiseptics and disinfectants. Table of Contents Chapter One: Introduction Study Objectives Reasons for Doing This Study Intended Audience Scope of The Study Methodology Information Sources About The Author Related BCC Reports BCC Online Services Disclaimer Chapter Two: Executive Summary Executive Summary Summary Table Worldwide Revenue of Antiseptics and, Through 2016 ($ Millions) Summary Figure Worldwide Revenue of Antiseptics and, ($ Millions) Chapter Three: Overview Definitions Mechanism of Action of Action On Membrane Denaturation of Cellular Proteins Inactivation of Key Enzymes Alkylation of Amino-group Damage To Nucleic Acids Selection Criteria for Disinfectant Speed of Action Efficacy Health and Safety Ecological Profile Material Compatibility Factors Affecting The Activity of Length of Time Age Concentration and Potency Temperature Ph Levels Hardness of Water Microbial Resistance Factors That Affect The Activity of Antiseptics Concentration
4 Table of Contents, continued Europe contributed to about 34% of the total market and was $1.3 billion in 2010 and has reached $1.4 billion in The European market is expected to grow at a CAGR of 11.2% and reach $2.4 billion by Presence of Organic Matter Contact Time Chapter Four: Classification Polyhexanide Chlorhexidine Phenol and Derivatives Phenol Hexachlorophene Triclosan Chloroxylenol Pentachlorophenol Quaternary Ammonium Compounds Benzalkonium Chloride Benzethonium Chloride Cetrimonium Compounds Cetylpyridinium Iodine Products Povidone Iodine Tincture of Iodine Silver Compounds Sodium Hypochlorite Calcium Hypochlorite Chloramines Table 1 Monochloramines Vs. Chlorine Disinfectant Chlorine Dioxide Hydrogen Peroxide Aldehydes Formaldehyde Glutaraldehyde Alcohols Other 8-hydroxyquinoline Dequalinium Chloroquinaldol Oxyquinoline Glycolic Acid Other Classification of Low-level Intermediate-level High-level Chapter Five: Regulatory Aspects Regulatory Aspects New Disinfectant Approvals Table 2 Approved and Antiseptics, Table 3 Number of New Product Approvals In Each Year, Figure 1 Number of New Product Approvals, Chapter Six: Industry Structure Manufacturers/ Suppliers of Table 4 Leading Manufacturers/suppliers of Table 5 Leading Manufacturers/suppliers of Phenol and Derivatives Table 6 Leading Manufacturers/suppliers of Iodine and Iodophors Table 7 Leading Manufacturers/suppliers of Quaternary Ammonium Products Table 8 Leading Manufacturers/suppliers of Silver Products Table 9 Leading Manufacturers/suppliers of Aldehyde-based Products Table 10 Leading Manufacturers/suppliers of Alcohol-based Products Table 11 Leading Manufacturers/suppliers of Table 12 Leading Manufacturers/suppliers of Others Category As Market Shares of Industry Leaders of Antiseptics and Table 13 Worldwide Market Shares of Manufacturers/ suppliers of, 2010 (%) Figure 2 Worldwide Market Shares of Manufacturers/ suppliers of, 2010 (%) Phenol and Derivatives Table 14 Worldwide Market Shares of Manufacturers/ suppliers of Phenol and Derivatives, 2010 (%) Figure 3 Worldwide Market Shares of Manufacturers/ suppliers of Phenol and Derivatives, 2010 (%) Iodine Products Table 15 Worldwide Market Shares of Manufacturers/ suppliers of Iodine Products, 2010 (%) Figure 4 Worldwide Market Shares of Manufacturers/ suppliers of Iodine Products, 2010 (%) Quarternary Ammonium Compounds Table 16 Worldwide Market Shares of Manufacturers/ Suppliers of Quarternary Ammonium Compounds, 2010 (%) Figure 5 Worldwide Market Shares of Manufacturers/ suppliers of Quarternary Ammonium Compounds, 2010 (%) Silver Products Table 17 Worldwide Market Shares of Manufacturers/ suppliers of Silver Products, 2010 (%) Figure 6 Worldwide Market Shares of Manufacturers/ suppliers of Silver Products, 2010 (%) Aldehydes Table 18 Worldwide Market Shares of Manufacturers/ suppliers of Aldehyde-based Products, 2010 (%) Figure 7 Worldwide Market Shares of Manufacturers/ suppliers of Aldehyde-based Products, 2010 (%) Alcohols Table 19 Worldwide Market Shares of Manufacturers/ suppliers of Alcohol-based Products, 2010 (%) Figure 8 Worldwide Market Shares of Manufacturers/ suppliers of Alcohol-based Products, 2010 (%) Table 20 Worldwide Market Shares of Manufacturers/ suppliers of, 2010 (%) Figure 9 Worldwide Market Shares of Manufacturers/ suppliers of, 2010 (%) Others Table 21 Worldwide Market Shares of Manufacturers/ suppliers of Others Category of, 2010 (%) Figure 10 Worldwide Market Shares of Manufacturers/ suppliers of Others Category of, 2010 (%) Chapter Seven: New Developments Table 22 New Developments, 2008 To March 2011 Some Other Developments In Research Institutes Chapter Eight: Market Analysis Table 23 Worldwide Market, 2009 To 2016 ($ Millions) Figure 11 Worldwide Market for, ($ Millions)
5 Table of Contents, continued Table 24 Worldwide Market for Biguanides and Amidines By Region, Through 2016 ($ Millions) Figure 12 Worldwide Market for Biguanides and Amidines By Region, Through 2016 ($ Millions) Phenol and Derivatives Table 25 Worldwide Market for Phenol and Derivatives By Region, Through 2016 ($ Millions) Figure 13 Worldwide Market for Phenol and Derivatives By Region, ($ Millions) Iodine Products Table 26 Worldwide Market for Iodine Products By Region, Through 2016 ($ Millions) Figure 14 Worldwide Market for Iodine Products By Region, ($ Millions) Quaternary Ammonium Compounds Table 27 Worldwide Market for Quaternary Ammonium Products By Region, Through 2016 ($ Millions) Figure 15 Worldwide Market for Quaternary Ammonium Products By Region, ($ Millions) Silver Products Table 28 Worldwide Market for Silver Products By Region, Through 2016 ($ Millions) Figure 16 Worldwide Market for Silver Products By Region, ($ Millions) Aldehyde Products Table 29 Worldwide Market for Aldehyde-based Products By Region, Through 2016 ($ Millions) Figure 17 Worldwide Market for Aldehyde-based Products By Region, ($ Millions) Alcohols Table 30 Worldwide Market for Alcohol-based Products By Region, Through 2016 ($ Millions) Figure 18 Worldwide Market for Alcohol-based Products By Region, ($ Millions) Table 31 Worldwide Market for By Region, Through 2016 ($ Millions) Figure 19 Worldwide Market for By Region, ($ Millions) Others Table 32 Worldwide Market for Others Category of By Region, Through 2016 ($ Millions) Figure 20 Worldwide Market for Others Category of By Region, ($ Millions) Market Shares of, By Region Table 33 Worldwide Disinfectant Market Shares By Region, 2010 (%) Figure 21 Worldwide Disinfectant Market Shares By Region, 2010 (%) Chapter Nine: Market By End Users Table 34 Global Market for By End Users, Through 2016 ($ Millions) Figure 22 Global Market for By End Users, ($ Millions) Domestic Table 35 Global Sales of Domestic, Through 2016 ($ Millions) Figure 23 Global Sales of Domestic, ($ Millions) Global Share Table 36 Global Share of Regions In Domestic In 2010 (%) Figure 24 Global Share of Regions In Domestic In 2010 (%) Institutional Table 37 Global Sales of Institutional, Through 2016 ($ Millions) Figure 25 Global Sales of Institutional, Through 2016 ($ Millions) Health Care Usage Table 38 Global Sales of Health Care, Through 2016 ($ Millions) Figure 26 Global Sales of Health Care, ($ Millions) Global Share Table 39 Global Share for Health Care In 2010 (%) Figure 27 Global Share of Health Care In 2010 (%) Industrial and Commercial Use Table 40 Global Market for Used In Industries and Commercial Places, Through 2016 ($ Millions) Figure 28 Global Market for Used In Industries and Commercial Places, ($ Millions) Global Share Table 41 Global Share for Industrial and Commercial, In 2010 (%) Figure 29 Global Share for Industrial and Commercial, In 2010 (%) Market Share of Applications Table 42 Share of By End Users, In 2010 (%) Figure 30 Share of By End Users, In 2010 (%) Chapter Ten: Patent Analysis Patents By Year Table 43 Number of Significant Patents By Year, (Number/%) Figure 31 Number of Significant Patents By Year, Figure 32 Number of Patents By Year, (%) Patents By Type Table 44 Number of Patents By Type, Figure 33 Patents By Type, (%) Patents By Company Table 45 Number of U.S. Patents By Company for, Figure 34 Number of U.S. Patents By Company for, Patents By Country Table 46 Number of U.S. Patents By Country,
6 Table of Contents, continued Figure 35 Number of U.S. Patents By Country, Patents By Assignee Type Table 47 Patents By Assignee Type for, Figure 36 Patents By Assignee Type for Antiseptics and, Chapter Eleven: Strategies and Prospects Factors Affecting The Market of Growing Awareness Involvement of Media Sharp Rise In Infections Swine Flu Outbreak Global Initiatives Demand of Application-specific Products Competition and Demand Manufacturer s Strategies Mergers and Acqisitions Chapter Twelve: Company Profiles Abc Compounding Company Actavis Agion Technologies Alda Pharmaceutical Corporation American Biotech Labs Amrep Inc. Aplicare Inc. Bio-cide International Inc. Biotech Medics Inc. Cantel Medical Corporation Cardinal Health Carefusion Corporation Ccp Industries Clorox Company (The) Colgate Palmolive Daley International Ltd. Dial Professional Series Diversey Inc. Dow Microbial Control Dupont Duraban Ecolab Inc. Gojo Industries Johnson & Johnson 3m Company Medical Chemical Corp. Melrose Chemical Ltd. Metrex Research Corporation Palmero Healthcare Procter and Gamble Company Professional Disposables International Pure Biosciences Reckitt Benckiser Safetec of America Sinofresh Healthcare Inc Sporicidin International Stepan Company Sterilex Corporation Steris Corporation Veridien Corporation Virox Technologies Xttrium Laboratories Chapter Thirteen: Appendix I abbreviations/ Definitions 134 pages 47 tables Related Reports ID: CHM052A Published: 02/09 Sterilization Technologies: The U.S. Market ID: CHM016E Published: 11/09 Chiral Technology: Global Markets ID: BIO012E Published: 03/10 About BCC Research BCC Research is a leading publisher of high-quality, technology market research reports and technical publications. BCC Research reports provide quantified measurements of the market and all major industry segments, as well as in-depth analysis of key market drivers and trends. BCC Subscriptions Access hundreds of published reports and automatically receive newly published research with a BCC Report Subscription. We can tailor a complete package of material that meets your needs and budget. BCC Custom Research Improve your strategic planning efforts with a BCC custom research study. We will work with you to determine what information is needed and deliver specific qualitative and quantitative analysis that supports your business objectives. Call or (intl), or sales@bccresearch.com for more information about any of BCC Research s products and services.
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