CURRICULUM VITAE. Warganegara (Citizenship) Bangsa (Race) Malaysia

Size: px

Start display at page:

Download "CURRICULUM VITAE. Warganegara (Citizenship) Bangsa (Race) Malaysia"

Everett Chandler
6 years ago
Views:

CURRICULUM VITAE A. BUTIR-BUTIR PERIBADI (Personal Details) Nama Penuh (Full Name) Norsharina Binti Ismail Gelaran (Title): Ms. No. MyKad / No. Pasport (Mykad No. / Passport No.

1 CURRICULUM VITAE A. BUTIR-BUTIR PERIBADI (Personal Details) Nama Penuh (Full Name) Norsharina Binti Ismail Gelaran (Title): Ms. No. MyKad / No. Pasport (Mykad No. / Passport No.) Warganegara (Citizenship) Bangsa (Race) Malay Jawatan (Designation) Research Officer Tarikh Lahir (Date of Birth) Jantina (Gender) Female 12 March 1982 Alamat Semasa (Current Address) Jabatan/Fakulti (Department/Faculty) E-mel dan URL ( Address and URL) Laboratory of Molecular Biomedicine, Institute of Bioscience, Universiti Putra, Serdang, Selangor,. Tel: Tel: Fax: B. KELAYAKAN AKADEMIK (Academic Qualification) Nama Sijil / Kelayakan Nama Sekolah Institusi (Certificate / Qualification obtained) (Name of School / Institution) Doctor of Philosophy (PhD.) Master (MSc.) First Degree (BSc.) Universiti Putra Tahun (Year obtained) present norsharina@upm.edu.my URL: - H/P: Bidang pengkhusususan (Area of Specialization) Neuroscience Universiti Putra 2009 Nutrition Universiti Putra 2004 Biotechnology C. KEMAHIRAN BAHASA (Language Proficiency) Bahasa / Language Lemah Poor (1) Sederhana Moderate (2) Baik Good (3) Amat Baik Very good (4) Cemerlang Excellent (5) English / Bahasa Melayu / Chinese Lain-lain (other): 1 / 3

2 D. PENGALAMAN SAINTIFIK DAN PENGKHUSUSAN (Scientific experience and Specialisation) Organization Position Start Date End Date Expertise E. PEKERJAAN (Employment) Majikan / Employer Jawatan / Designation Jabatan / Department Tarikh lantikan / Start Date Universiti Putra Research Officer Laboratory of Molecular Biomedicine, Institute of Bioscience Tarikh tamat / Date Ended 2 Feb March 2042 F. ANUGERAH DAN HADIAH (Honours and Awards) Name of awards Title Award Authority Award Type Year Academic Awards Best Poster The 2nd International Symposium and Workshop on Functional Genomics and Structural Biology (FGSB 2014), Mines Wellness Hotel, Seri Kembangan, Selangor, International 2014 The 1st Best Poster Gold Medal Silver Medal International Seminar of Natural Product Medicines 2012, Bandung, Indonesia The International Exhibition of Ideas Inventions New Products (iena), Nuremberg, Germany International 2012 International 2009 National / 3

3 Non-Academic Awards The best Master thesis Silver Medal The 1st Best Poster Silver Medal Bronze Medal Gold Medal Silver Medal Bronze medal 25th Nutrition Society Annual Scientific Conference n Technology Expo (MTE) Seminar Minyak dan Lemak Kebangsaan 2008 National 2010 National 2009 National Awards of Merit G. SENARAI PENERBITAN (Sila masukan nama pengarang, tajuk, nama jurnal, jilid, muka surat dan tahun diterbitkan) (List of publications author (s), title, journal, volume, page and year published) Journal 1. Norsharina Ismail, Maznah Ismail, Nur Hanisah Azmi, Muhammad Firdaus Abu Bakar, Hamidon Basri, and Maizaton Atmadini Abdullah. Modulation of Hydrogen Peroxide-Induced Oxidative Stress in Human Neuronal Cells by Thymoquinone-Rich Fraction and Thymoquinone via Transcriptomic Regulation of Antioxidant and Apoptotic Signaling Genes. Oxidative Medicine and Cellular Longevity Volume 2016, Article ID , 15 pages, / 3

4 2. Jhi Biau Foo, Latifah Saiful Yazan, Yin Sim Tor, Agustono Wibowo, Norsharina Ismail, Nurdin Armania, Yoke Kqueen Cheah, Rasedee Abdullah. Dillenia suffruticosa dichloromethane root extract induced apoptosis towards MDA-MB-231 triple-negative breast cancer cells. Journal of Ethnopharmacology 187, , Norsharina Ismail, Muhammad Nadeem Akhtar, Maznah Ismail, Seema Zareen, Syed Adnan Ali Shah, Nordin Hj Lajis and Saiful N. Tajuddin. Neuroprotective effect from stem bark extracts of Knema laurina against H2O2- and Aβ1 42-induced cell death in human SH-SY5Y cells. Natural Product Research 29(16), , Nur Hanisah Azmi, Maznah Ismail, Norsharina Ismail, Mustapha Umar Imam, Noorjahan Banu Alitheen and Maizaton Atmadini Abdullah. Germinated brown rice alters Aß1-42 aggregation and modulates Alzheimer s disease-related genes in differentiated human SH-SY5Y cells. Evidence-Based Complementary and Alternative Medicine Volume 2015, Article ID , 12 pages, Zhang Yida, Mustapha Umar Imam, Maznah Ismail, WaiTeng Wong, Maizaton Atmadini Abdullah, Aini Ideris and Norsharina Ismail. N- Acetylneuraminic acid attenuates hypercoagulation on high fat dietinduced hyperlipidemia rats. Food & Nutrition Research 2015, 59, 29046, Yida, Z., Imam, M. U., Ismail, M., Ismail, N, Azmi, N. H, Wong W. & Abdullah, M. A. N-acetylneuraminic acid supplementation prevents high fat diet-induced insulin resistance in rats through transcriptional and non-transcriptional mechanisms. Biomed Research International 2015, 10 pages, Yida, Z., Imam, M. U., Ismail, M., Ismail, N, Ideris, A., & Abdullah, M. A. High fat diet-induced inflammation and oxidative stress are attenuated by N-acetylneuraminic acid in rats. Journal of Biomedical Science 22(96), 1-10, Yida, Z., Imam, M. U., Ismail, M., Hou, Z., Abdullah, M. A., Ideris, A., & Ismail, N. Edible Bird s Nest attenuates high fat diet-induced oxidative stress and inflammation via regulation of hepatic antioxidant and inflammatory genes. BMC Complementary and Alternative Medicine 15(1), 310, Yida, Z., Imam, M. U., Ismail, M., Ismail, N., & Hou, Z. Edible bird s nest attenuates procoagulation effects of high-fat diet in rats. Drug Design, Development and Therapy 2015, 9, 3951, Yin Sim Tor, Latifah Saiful Yazan, Jhi Biau Foo, Agustono Wibowo, Norsharina Ismail, Yoke Kqueen Cheah, Rasedee Abdullah. Induction of apoptosis in MCF-7 cells via oxidative stress generation, mitochondria-dependent and caspase-independent pathway by ethyl 4 / 3

5 acetate extract of Dillenia suffruticosa, and its chemical profile. Plos One 10(6), e , Jhi Biau Foo, Saiful Yazan Latifah, Yin Sim Tor, Agustono Wibowo, Norsharina Ismail, Nurdin Armania, Su Peng Loh, Intan Safinar Ismail, Yoke Kqueen Cheah, Rasedee Abdullah. Induction of cell cycle arrest and apoptosis by betulinic acid-rich fraction from Dillenia suffruticosa root in MCF-7 cells involved p53/p21 and mitochondrial signalling pathway. Journal of Ethnopharmacology 166, , Zhang Yida, Mustapha Umar Imam, Maznah Ismail, Der-Jiun Ooi, Nadarajan Sarega, Nur Hanisah Azmi, Norsharina Ismail, Kim Wei Chan, Zhiping Hou, Norhayati Yusuf. Edible Bird s Nest Prevents High Fat Diet-Induced Insulin Resistance in Rats. Journal of Diabetes Research 2015, 11 pages, Hou Zhiping, Mustapha Umar Imam, Maznah Ismail, Norsharina Ismail, Zhang Yida, Aini Ideris, Nadarajan Sarega and Rozi Mahmud. Effects of Edible Bird s Nest on hippocampal and cortical neurodegeneration in ovariectomized rats. Food & Function 2015, 6, 1701, Hou Zhiping, Mustapha Umar Imam, Maznah Ismail, Nur Hanisah Azmi, Norsharina Ismail, Aini Ideris and Rozi Mahmud. Lactoferrin and ovotransferrin contribute toward antioxidative effects of edible bird s nest against hydrogen peroxide-induced oxidative stress in human SH-SY5Y cells. Bioscience, Biotechnology and Biochemistry 79, 10, , Norsharina Ismail, Maznah Ismail, Mustapha Umar Imam, Nur Hanisah Azmi, Siti Farhana Fathy and Jhi Biau Foo. Mechanistic basis for protection of differentiated SH-SY5Y cells by oryzanol-rich fraction against hydrogen peroxide-induced neurotoxicity. BMC Complementary and Alternative Medicine 14:467, 11 pages, Jhi Biau Foo, Latifah Saiful Yazan, Yin Sim Tor, Nurdin Armania, Norsharina Ismail, Mustapha Umar Imam, Swee Keong Yeap, Yoke Kqueen Cheah, Rasedee Abdullah and Maznah Ismail. Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signaling pathways. BMC Complementary and Alternative Medicine 14:197, 16 pages, Yin Sim Tor, Latifah Saiful Yazan, Jhi Biau Foo, Nurdin Armania, Yoke Kqueen Cheah, Rasedee Abdullah, Mustapha Umar Imam, Norsharina Ismail and Maznah Ismail. Induction of apoptosis through oxidative stress-related pathways in MCF-7, human breast cancer cells, by ethyl acetate extract of Dillenia suffruticosa. BMC Complementary and Alternative Medicine 14(55), 12 pages, / 3

6 18. Norsharina Ismail, Maznah Ismail, Musalmah Mazlan, Latiffah Abdul Latiff, Mustapha Umar Imam, Shahid Iqbal, Nur Hanisah Azmi, Siti Aisyah Abd Ghafar, Kim Wei Chan. Thymoquinone Prevents β-amyloid Neurotoxicity in Primary Cultured Cerebellar Granule Neurons. Cellular and Molecular Neurobiology 33(8), , Nur Hanisah Azmi, Norsharina Ismail, Mustapha Umar Imam and Maznah Ismail. Ethyl acetate extract of germinated brown rice attenuates hydrogen peroxide-induced oxidative stress in human SH- SY5Y neuroblastoma cells: role of anti-apoptotic, pro-survival and antioxidant genes. BMC Complementary and Alternative Medicine 13 (177), 11 pages, Siti Aisyah Abd Ghafar, Maznah Ismail, Latifah Saiful Yazan, Sharida Fakurazi, Norsharina Ismail, KimWei Chan, and Paridah Md Tahir. Cytotoxic Activity of Kenaf Seed Oils from Supercritical Carbon Dioxide Fluid Extraction towards Human Colorectal Cancer (HT29) Cell Lines. Evidence-Based Complementary and Alternative Medicine 2013, 8 pages, Nurdin Armania, Latifah Saiful Yazan, Jhi Biau Foo, Yim Sim Tor, Nurshafini Ishak, Intan Safinar Ismail, Norsharina Ismail, Maznah Ismail. Dillenia suffruticosa extract inhibits proliferation of human breast cancer cell lines (MCF-7 and MDA-MB-231) via induction of G2/M arrest and apoptosis. Molecules 18(18), 6 pages, Mustapha Umar Imam, Nur Hanisah Azmi, Muhammad Iqbal Bhanger, Norsharina Ismail, Maznah Ismail. Antidiabetic properties of germinated brown rice: A systematic review. Evidence-Based Complementary and Alternative Medicine 2012, 12 pages, Norsharina Ismail, Maznah Ismail, Siti Farhana Fathy, Siti Nor Asma Musa, Mustapha Umar Imam, Jhi Biau Foo and Shahid Iqbal. Neuroprotective Effects of Germinated Brown Rice against Hydrogen Peroxide Induced Cell Death in Human SH-SY5Y Cells. International Journal of Molecular Sciences 13, , A.A. Mariod, R.M. Ibrahim, M. Ismail and N. Ismail. Antioxidant activity of phenolic extracts from kenaf (Hibiscus cannabinus) seedcake. Grasas Y Aceites 63(2), , Foo Jhi Biau, Latifah Saiful Yazan, Norsharina Ismail, Siti Muskinah Mansor, Paridah Md. Tahir and Maznah Ismail. Kenaf seed oil from SFE inhibits the proliferation of WEHI-3B leukemia cells in vivo. Journal of Medicinal Plants Research 6(8), , Ismail Norsharina, Ismail Maznah, Al-Absi Aied, Al-Naqeeb Ghanya. Thymoquinone Rich Fraction from Nigella sativa and Thymoquinone are Cytotoxic towards Colon and Leukemic Carcinoma Cell Lines. Journal of Medicinal Plants Research 5(15), , / 3

7 27. KetLi Ho, Latifah Saiful Yazan, Norsharina Ismail, Maznah Ismail. Toxicology Study of Toxicology study of vanillin on rats via oral and intra-peritoneal administration. Food and Chemical Toxicology 49(1), 25-30, Saad Norazalina, Mohd Esa Norhaizan, Ithnin Hairuszah, Abdul Rahman Sabariah, Shafie Nurul Husna, Ismail Norsharina. Antiproliferation and apoptosis induction of phytic acid in hepatocellular carcinoma (HEPG2) cell lines. African Journal of Biotechnology 10(73), , Abdalbasit Adam Mariod, Hadiza Altine Adamu, Ismail Maznah, Ismail Norsharina. Antioxidative effects of stabilized and unstabilized defatted rice bran methanolic extracts on the stability of rice bran oil under accelerated conditions. Grasas Y Aceites 61(4), , Abdalbasit Adam Mariod, Ramlah Mohamad Ibrahim, Maznah Ismail and Norsharina Ismail. Antioxidant Activity of the Phenolic Leaf Extracts from Monechma ciliatum in Stabilization of Corn Oil. Journal of the American Oil Chemists Society 87(1), 35-43, Abdalbasit Adam Mariod, Ramlah Mohamad Ibrahim, Maznah Ismail and Norsharina Ismail. Antioxidant activities of phenolic rich fractions (PRFs) obtained from black mahlab (Monechma ciliatum) and white mahlab (Prunus mahaleb) seedcakes. Food Chemistry 118(1), , Shafie Nurul-Husna, Mohd Esa Norhaizan, Ithnin Hairuszah, Md Akim Abdah, Saad Norazalina, Ismail Norsharina. Rice Bran Phytic Acid (IP6) Induces Growth Inhibition, Cell Cycle Arrest and Apoptosis on Human Colorectal Adenocarcinoma Cells. Journal of Medicinal Plants Research 4(21), , Fatemeh Abedini, Hossein Hosseinkhani, Maznah Ismail, Tengku Azmi, Abdul Rahman Omar, Chong Pei Pei, Norsharina Ismail, Ira-Yudovin Farber, Abraham J. Domb. Toxicity evaluation of dextran-spermine polycation as a tool for gene therapy in vitro. Journal of Cell and Animal Biology 4(12), , Abdalbasit Adam Mariod, Ramlah Mohamad Ibrahim, Maznah Ismail and Norsharina Ismail. Antioxidant activity and phenolic content of phenolic rich fractions obtained from black cumin (Nigella sativa) seedcake. Food Chemistry 116, , KetLi Ho, Latifah Saiful Yazan, Norsharina Ismail, Maznah Ismail. Apoptosis and cell cycle arrest of human colorectal cancer cell line HT- 29 induced by vanillin. Cancer Epidemiology 33, , Norsharina Ismail, Maznah Ismail, Latiffah A. Latiff, Musalmah Mazlan, Abdalbasit Mariod. Black cumin seed (Nigella sativa Linn.) oil 7 / 3

8 Books/Monographs - and its fractions protect against beta amyloid peptide-induced toxicity in primary cerebellar granule neurons. Journal of Food Lipids 15, , Chapter in book - Proceedings - Other publications (Conference Abstract) 1. Norsharina Ismail, Maznah Ismail, Nur Hanisah Azmi, Muhammad Firdaus Abu Bakar, Johnson Stanslas, Dahiru Sani, Hamidon Basri and Maizaton Atmadini Abdullah. Neuroprotective effects of thymoquinonerich fraction nanoemulsion in hypercholesterolemia-induced rat model of sporadic Alzheimer's disease. 14th Meeting of the Asian-Pacific Society for Neurochemistry, Kuala Lumpur,, Nur Hanisah Azmi, Maznah Ismail, Norsharina Ismail, Noorjahan Banu Mohammed Alitheen and Maizaton Atmadini Abdullah. Germinated brown rice regulates brain oxidative stress, inflammation and acetylcholinesterase level: implication in neurodegenerative diseases. 14th Meeting of the Asian-Pacific Society for Neurochemistry, Kuala Lumpur,, N. Ismail, M. Ismail, N.H. Azmi, M.U. Imam, M.F. Abu Bakar, H. Basri and M.A. Abdullah. Modulation of Gene Expression Level by Thymoquinone and Thymoquinone-rich Fraction in Response to Reactive Oxygen Species Generation on Differentiated Human SH- SY5Y Cells. Golden Helix Symposium-Next Generation Pharmacogenomics, Kuala Lumpur,, N.H. Azmi, M. Ismail, N. Ismail, M.U. Imam, N.B. Mohamed Alitheen, M.A. Abdullah. Multiplex Gene Expression Approach for the Elucidation of Germinated Brown Rice s Neuroprotective Mechanism of Action. Golden Helix Symposium - Next Generation Pharmacogenomics, Kuala Lumpur,, Norsharina Ismail, Maznah Ismail, Nur Hanisah Azmi, Mustapha Umar Imam, Hamidon Basri and Maizaton Atmadini Abdullah. Multiplex Gene Expression on Neuroprotective Effects of Thymoquinone against Hydrogen Peroxide-Induced Oxidative Stress in Differentiated Human Neuroblastoma SH-SY5Y Cells. The 2nd International Symposium and Workshop on Functional Genomics and Structural Biology (FGSB 2014), Mines Wellness Hotel, Seri Kembangan, Selangor,, Nur Hanisah Azmi, Norsharina Ismail, Mustapha Umar Imam, Noorjahan Banu Mohamed Alitheen, Maizaton Atmadini Abdullah and Maznah Ismail. Germinated Brown Rice Extract Modulates Amyloidogenic Processing Pathway of Alzheimer s β-amyloid Precursor Protein Induced by Hydrogen Peroxide in Differentiated SH-SY5Y Neuronal Cells. The 2nd International Symposium and Workshop on 8 / 3

9 Functional Genomics and Structural Biology (FGSB 2014), Mines Wellness Hotel, Seri Kembangan, Selangor,, Norsharina Ismail, Maznah Ismail, Mustapha Umar Imam and Nur Hanisah Azmi. Germinated brown rice extract protects neuronal cells from apoptosis through Akt activation and p53 inhibition. International Seminar on Natural Product Medicines 2012 (ISNPM 2012), Bandung, Indonesia, Norsharina Ismail, Maznah Ismail and Siti Nor Asma Musa. Neuroprotective effects of germinated brown rice on hydrogen peroxide-induced cell death in SH-SY5Y cells. International Conference of Natural Products ICNP 2011, Palm Garden Hotel, Putrajaya, Norsharina Ismail, Maznah Ismail, Latiffah A. Latiff, Musalmah Mazlan and Abdalbasit A. Mariod. Black cumin seed (Nigella sativa Linn) oil and its fractions protect against β-amyloid peptide induced toxicity in primary cerebellar granule neurons. Seminar Minyak dan Lemak Kebangsaan 2008, Hyatt Regency Resort, Kuantan, Pahang, Norsharina Ismail, Maznah Ismail, Latiffah A. Latiff and Musalmah Mazlan. Nigella sativa Oil and Thymoquinone Protects Aβ peptideinduced Cell Death in Cultured Cerebellar Granule Neurons. International Conference Exploring New Frontiers in Medicine and Health, PWTC, Kuala Lumpur, Computer software Norsharina Ismail, Maznah Ismail, Latiffah A. Latiff and Musalmah Mazlan. Nigella sativa Oil and Thymoquinone Protects Aβ peptideinduced Cell Death in Cultured Cerebellar Granule Neurons. 6th COSTAM/SFRR (Asean/) International Workshop, Holiday Inn Resort Damai Beach, Kuching, Sarawak, H. PROJEK PENYELIDIKAN TERDAHULU(Past Research Project) Project No. Project Title Role Year Source of fund Status RU Nutrigenomics profiling of human neuronal SHSY5Y pre-treated with extracts formulation following exposure to Alzheimer s β-amyloid peptide and hydrogen peroxide in vitro Nutraceutical properties and probiotic potential of stingless bee honey for establishment of quality Project Leader 2009 Research University Grant Scheme (RUGS) 2016 Skim Geran Penyelidikan Trans-Disciplinary (TRGS), Ministry of Education, On-going 9 / 3

10 FR I-ECO/29 (-13) SF SF197 markers against oxidative stress Development of novel nano lipid delivery systems for alternative hypocholesterolemic drugs from oryzanol, thymoquinone and their rich fractions Biodistribution and Blood Brain Barrier Permeation of Novel Thymoquinone-Rich Fraction (TQRF) Nanoemulsion in Sporadic Rat Model of Alzheimer s Disease Improved Bakery Product with Stabilized Rice Bran for the Economy and Health Society Quality and anti-aging determinants of edible bird's nest (EBN) by nutrigenomic and metabolomic strategies Development of novel functional meat products with cardioprotective properties and enhanced shelf-life quality by incorporation of defatted kenaf seed meal (DKSM) 2011 Ministry of Science, Technology & Innovation, (Nanotechnology Research Grant) 2013 Fundamental Research Grant Scheme (FRGS) 2013 Knowledge Transfer Program (KTP) 2012 Ministry of Science, Technology & Innovation, (Ketetapan/ Pelarasan Keaslian Sarang Burung Walit) 2013 Ministry of Science, Technology & Innovation, e-science Fund I. ID PUBLISHING (Publishing ID) Author ID Name Scopus Norsharina Ismail ORC ID Norsharina Ismail Web of Science ID Researcher ID Others 10 / 3

11 J. RANGKAIAN SOSIAL (Social Networking) Facebook LinkedIn Researchgate Academia Google Scholar Blog Website url Others 11 / 3

CURRICULUM VITAE. HARMAEN AHMAD SAFFIAN Bangsa (Race. Warganegara (Citizenship) MALAYSIA ) MALAY SENIOR RESEARCH OFFICER (Q48)

CURRICULUM VITAE. HARMAEN AHMAD SAFFIAN Bangsa (Race. Warganegara (Citizenship) MALAYSIA ) MALAY SENIOR RESEARCH OFFICER (Q48) CURRICULUM VITAE A. BUTIR-BUTIR PERIBADI (Personal Details) Nama Penuh (Full Name) No. MyKad / No. Pasport (Mykad No. / Passport No.) Jawatan (Designation) HARMAEN AHMAD SAFFIAN Bangsa (Race Warganegara