catalogue Key Organics Chemistry Innovation Quality

Transcription

1 2013 catalogue Key Organics Chemistry Innovation Quality

2 1 Key Organics Chemistry Innovation Quality The Key Organics portfolio offers a diverse range of chemistry products and services tailored to the Pharmaceutical, Agrochemical and Biotechnology sectors together with related industries and applications. The long-established and well-recognised BIONET brand consists of a database containing over 65,000 products, featuring Biochemicals, Fragments, Research Intermediates and Screening Compounds. Key Organics Chemistry Services team offers core solutions including Custom Synthesis, FTE/Contract Synthesis, Analytical Chemistry, Collaborative R&D, Process R&D/Scale-up and more. We are committed to the delivery of high quality compounds, on time with complete confidentiality and reliability. With over 26 years proven expertise and competence, we are well positioned to become a long-term strategic partner for you and your chemistry needs. Contact us today to discuss your company s needs. Whether you need a few mg of a research compound, a several kg scale-up project or a long-term FTE, we have a solution for you. Products Collaborative R&D FTE Services Custom Synthesis Process R&D/Scale-up Analytical Chemistry Consultancy NEW NEW Intermediates Fragment Libraries Biochemicals Screening Compounds

3 2 Visit our new web shop to browse by therapeutic area or pharmacology HOW TO ORDER PRODUCT USAGE KEY TO LISTINGS

4 3 CONTENTS NEW

5 4 DEUTERATED APIs

6 5

7 6

8 7 ADRENERGIC RECEPTOR

9 8

10 9

11 10

12 11

13 12 ANTIANDROGEN

14 13 CYCLOOXYGENASE INHIBITORS

15 14

16 15

17 16 DNA GYRASE

18 17

19 18 DOPAMINE RECEPTOR

20 19

21 20

22 21

23 22 ENDOTHELIN RECEPTOR EPIGENETICS

24 23

25 24 GAMMA AMINO BUTYRIC ACID

26 25 GONADOTROPIN RELEASING HORMONE

27 26 GTPase HISTAMINE RECEPTOR

28 27

29 28 HORMONE

30 29

31 30 ION CHANNELS

32 31

33 32

34 33

35 34 MONOAMINE OXIDASE INHIBITORS

36 35 MUSCARINIC RECEPTOR

37 36

38 37

39 38 N-METHYL D ASPARTATE RECEPTOR OPIOID RECEPTOR

40 39 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS

41 40 PHOSPHO DIESTERASE INHIBITORS

42 41

43 42

44 43 PROTEASE INHIBITORS

45 44 PROTEIN KINASE INHIBITORS

46 45

47 46

48 47

49 48 PROTON PUMP INHIBITORS

50 49 RETINOBLASTOMA BINDING PROTEIN 9 REVERSE TRANSCRIPTASE INHIBITORS

51 50

52 51

53 52 SEROTONIN RECEPTOR

54 53

55 54

56 55

57 56 STEROIDS

58 57 THROMBIN INHIBITORS TUMOUR NECROSIS FACTOR

59 58 VANILLOID RECEPTOR VIRAL POLYMERASE

60 59 FTE/Contract Synthesis Custom Synthesis Library Design & Synthesis Analytical Services Collaborative R&D Process R&D/Scale-up Hit-to-Lead Optimisation Consultancy Service With extensive experience in a wide range of industry disciplines, an integrated project management approach, guaranteed confidentiality and full integrity, we offer reliable solutions for your chemistry outsourcing needs. Our dedicated Chemistry Services team offers core solutions including FTE & Contract Synthesis, Custom Synthesis, Analytical Chemistry, Collaborative R&D, Process R&D/Scale-up and much more. The team is highly qualified, with direct experience of major pharma and biotech companies, so we understand the challenges behind the drug development process and can undertake technology transfer and scale-up activities. We have a well-established, proven track record and reputation for providing consistent, reliable and quality service with outstanding customer support, technical expertise & back-up, offering guaranteed confidentiality as well as reassuringly high levels of performance. Target Discovery Lead Finding Lead Optimization Candidate Selection Pre- Clinical Phase I Phase II Phase III Product Approval Discovery Services Target Validation Medicinal Chemistry Biocatalysis* Custom Synthesis Natural Products Structure ID Fragment Design Biochemicals Early Development Chemical Process Development Analytical Development Kilo Lab Scale-Up Phase 1 GMP* Salt & Polymorph Investigations* Impurity Identification Formulation Development* Contract Manufacturing High Value Intermediates Process R&D PRI Identification *through select partners

61 60 NOTES

62 Key Organics Chemistry Innovation Quality For more information, please contact us at: Key Organics Ltd., Highfield Road Industrial Estate, Camelford, Cornwall PL32 9RA, United Kingdom T: +44 (0) F: +44 (0) E: