For research use only. Not for use in diagnostic procedures. CHEMTREC: (INTERNATIONAL) (NORTH AMERICA)

Transcription

1 SAFETY DATA SHEET Issuing date 20-Apr-2007 MSDS P/N: REV. F 1. IDENTIFICATION OF THE SUBSTANCE/PREPARATION AND THE COMPANY/UNDERTAKING Product Code , Product Name /2-Propanol Trade Name(s) SOLVENT B2, ACETONITRILE/2-PROPANOL; ACETONITRILE/IPA; SOLVENT B/2- PROPANOL Recommended Use For research use only. Not for use in diagnostic procedures. Contact Manufacturer APPLIED BIOSYSTEMS 7 KINGSLAND GRANGE, WOOLSTON WARRINGTON, CHESHIRE WA1 4SR Telephone: (UK) Fax: Emergency Telephone Number CHEMTREC: (INTERNATIONAL) (NORTH AMERICA) 2. COMPOSITION/INFORMATION ON INGREDIENTS Chemical nature of the preparation Mixture of organic compounds. Haz/Non-haz Chemical Name EINECS-No. CAS-No Weight % Classification Isopropyl alcohol F;R11 Xi;R36 R F;R11 Xn;R20/21/22 Xi;R36 For the full text of the R phrases mentioned in this Section, see Section HAZARDS IDENTIFICATION The preparation is classified as dangerous in accordance with Directive 1999/45/EC. Classification F;R11 Xn;R20/21/22 Xi;R36 F - Highly flammable. Xn - Harmful. Most Important Hazards Highly flammable. Irritating to eyes. Harmful by inhalation, in contact with skin and if swallowed. Properties Affecting Health Inhalation of high vapour concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting. Page 1 / 7

2 4. FIRST AID MEASURES General advice Eye contact contact Ingestion Inhalation Notes to physician Protection of first-aiders Immediate medical attention is required. Show this safety data sheet to the doctor in attendance. Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Keep eye wide open while rinsing. If symptoms persist, call a physician. Wash off immediately with plenty of water. If skin irritation persists, call a physician. Call a physician or Poison Control Centre immediately. Do NOT induce vomiting. Rinse mouth. Drink plenty of water. Never give anything by mouth to an unconscious person. Call a physician or Poison Control Centre immediately. Move to fresh air in case of accidental inhalation of vapours. If breathing is irregular or stopped, administer artificial respiration. Treat symptomatically. Remove all sources of ignition. Use personal protective equipment. Avoid direct contact with skin. Use barrier to give mouth-to-mouth resuscitation. 5. FIRE-FIGHTING MEASURES Suitable extinguishing media Water spray. Carbon dioxide (CO2). Dry powder. Alcohol-resistant foam. Cool containers with flooding quantities of water until well after fire is out. Extinguishing media which must not be used for safety reasons Specific hazards Flammable. Vapors may travel to source of ignition and flash back. Special protective equipment for firefighters In the event of fire, wear self-contained breathing apparatus. 6. ACCIDENTAL RELEASE MEASURES Environmental precautions Personal precautions Methods for cleaning up Methods for Containment Prevent further leakage or spillage if safe to do so. Prevent product from entering drains. Do not flush into surface water or sanitary sewer system. Remove all sources of ignition. Evacuate personnel to safe areas. Ensure adequate ventilation. Use personal protective equipment. Keep people away from and upwind of spill/leak. Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Ground and bond containers when transferring material. Keep in suitable, closed containers for disposal. Clean contaminated surface thoroughly. Prevent further leakage or spillage if safe to do so. Other information Refer to protective measures listed in Sections 7 and HANDLING AND STORAGE Page 2 / 7

3 7. HANDLING AND STORAGE Handling Wear personal protective equipment. Avoid contact with skin, eyes and clothing. Ensure adequate ventilation. Keep away from open flames, hot surfaces and sources of ignition. Take necessary action to avoid static electricity discharge (which might cause ignition of organic vapours). Use only in area provided with appropriate exhaust ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Storage Keep containers tightly closed in a dry, cool and well-ventilated place. Keep away from heat and sources of ignition. Keep in properly labelled containers. 8. EXPOSURE CONTROLS / PERSONAL PROTECTION Exposure Limits Chemical Name EU The United Kingdom France Spain Germany Isopropyl alcohol VLCT: 400 ppm MAK: 200 ppm VLCT: 980 mg/m 3 MAK: 500 mg/m TWA: 70 mg/m 3 STEL: 1250 mg/m³ TWA: 400 ppm STEL: 500 ppm TWA: 999 mg/m³ STEL: 102 mg/m³ STEL: 60 ppm TWA: 68 mg/m³ VME: 40 ppm VME: 70 mg/m 3 VLA-EC: 500 ppm VLA- EC; 1250 mg/m 3 VLA- EC VLA-ED: 400 ppm VLA- ED; 998 mg/m 3 VLA-ED VLA-ED: 40 ppm VLA- ED; 68 mg/m 3 VLA-ED Ceiling / Peak: 400 ppm Ceiling / Peak: 1000 mg/m 3 TWA: 500 mg/m 3 TWA: 200 ppm MAK: 20 ppm MAK: 34 mg/m 3 Ceiling / Peak: 40 ppm Ceiling / Peak: 68 mg/m 3 TWA: 20 ppm TWA: 34 mg/m 3 Chemical Name Italy Portugal The Netherlands Finland Denmark Isopropyl alcohol STEL: 500 ppm TWA: 400 ppm MAC: 250 ppm MAC; 650 mg/m 3 MAC TWA: 200 ppm TWA: 500 mg/m 3 STEL: 250 ppm STEL: 620 mg/m 3 TWA: 200 ppm TWA: 490 mg/m TWA: 20 ppm MAC: 34 mg/m 3 MAC TWA: 68 mg/m 3 STEL: 100 mg/m 3 STEL: 60 ppm TWA: 70 mg/m 3 Chemical Name Austria Switzerland Poland Norway Ireland Isopropyl alcohol TWA: 100 ppm Occupational Exposure Controls STEL: 800 ppm STEL; 2000 mg/m 3 STEL MAK: 200 ppm MAK; 500 mg/m 3 MAK STEL 160 ppm STEL; 280 mg/m 3 STEL MAK: 40 ppm MAK; 70 mg/m 3 MAK STEL: 400 ppm STEL; 1000 mg/m 3 STEL MAK: 200 ppm MAK; 500 mg/m 3 MAK STEL: 40 ppm STEL; 68 mg/m 3 STEL MAK: 20 ppm MAK; 34 mg/m 3 MAK NDSCh: 1200 mg/m 3 NDS: 900 mg/m 3 NDSCh: 140 mg/m 3 NDS: 70 mg/m 3 TWA: 30 ppm TWA: 400 ppm TWA: 980 mg/m 3 STEL: 1225 mg/m 3 STEL: 500 ppm TWA: 70 mg/m 3 STEL: 105 mg/m 3 STEL: 60 ppm Engineering measures Personal protective equipment Respiratory protection Eye protection and body protection Hand protection Showers, eyewash stations, and ventilation systems. In case of insufficient ventilation wear suitable respiratory equipment. Tightly fitting safety goggles. Face-shield. Wear fire/flame resistant/retardant clothing. Long sleeved clothing. Butyl rubber. Page 3 / 7

4 Hygiene measures Environmental exposure controls When using, do not eat, drink or smoke. Regular cleaning of equipment, work area and clothing. Do not allow material to contaminate ground water system. 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Colourless. Odour Medicinal. Physical state Liquid. ph Flash point 6 C / 43 F Autoignition temperature Boiling point/range 82 C / 180 F Melting point/range Flammability Limits in Air Upper 16% Lower 3% Specific Gravity Water solubility Completely soluble. Solubility Ethanol. Ether. Acetone. Chloroform. Evaporation rate Vapour pressure Vapour density VOC content 100% Viscosity 10. STABILITY AND REACTIVITY Stability Conditions to avoid Materials to avoid Stable under normal conditions. Keep away from open flames, hot surfaces and sources of ignition. Strong oxidizing agents. Strong reducing agents. Acids. Bases. Halogens. Hazardous decomposition products Hydrogen cyanide. Nitrogen oxides (NOx). Carbon monoxide. Carbon dioxide (CO2). Sulfur oxides. Hazardous polymerisation Hazardous polymerisation does not occur. 11. TOXICOLOGICAL INFORMATION Acute Toxicity Product Information. Chronic Toxicity Reproductive Toxicity Developmental Toxicity Target Organ Effects This product does not contain any known or suspected reproductive hazards. Central nervous system (CNS). Central Vascular System (CVS). Eyes. Kidney. Liver. Respiratory system.. Blood. Thyroid. Page 4 / 7

5 Ecotoxicity Ecotoxicity effects. 12. ECOLOGICAL INFORMATION Chemical Name Toxicity to algae Toxicity to fish Microtox Data Daphnia magna (Water flea) Isopropyl alcohol EC50 > 1000 mg/l 72 h EC50 > 1000 mg/l 96 h LC50= mg/l LC50= mg/l LC50= 9640 mg/l EC50 = mg/l 5 min EC50 = mg/l 48 h LC50= 1000 mg/l LC50= 1640 mg/l LC50= 1650 mg/l Poecilia reticulata 96 h LC50= 1850 mg/l Lepomis macrochirus 96 h EC50 = mg/l 48 h EC50 = 73 mg/l 24 h EC50 = 7500 mg/l 15 h EC50 = 5838 mg/l 18 h Persistence and degradability Bioaccumulative potential Mobility Product has a low potential to bioconcentrate. The product is water soluble, and may spread in water systems. The product contains volatile organic compounds (VOC) which will evaporate easily from all surfaces. Chemical Name log Pow Isopropyl alcohol DISPOSAL CONSIDERATIONS Waste from residues / unused products Contaminated packaging Dispose of as hazardous waste in compliance with local and national regulations. Dispose of in accordance with local regulations. EWC waste disposal No Other information According to the European Waste Catalogue, Waste Codes are not product specific, but application specific. Waste codes should be assigned by the user based on the application for which the product was used. 14. TRANSPORT INFORMATION IMDG/IMO Proper shipping name Flammable liquid, n.o.s. EmS F-E, _S-E_, Flammable liquid, n.o.s. (, Isopropyl alcohol solution), 3, PG RID Page 5 / 7

6 14. TRANSPORT INFORMATION Proper shipping name Flammable liquid, n.o.s. Classification Code F1 Flammable liquid, n.o.s. (, Isopropyl alcohol solution), 3,, RID ADR/RID-Labels 3 ADR ICAO Proper shipping name Flammable liquid, n.o.s. Classification Code F1 Flammable liquid, n.o.s.(,isopropyl alcohol),3,,adr ADR/RID-Labels 3 Proper shipping name Flammable liquid, n.o.s.* Flammable liquid, n.o.s.* (, Isopropyl alcohol solution), 3,, PG ICAO/IATA Proper shipping name Flammable liquid, n.o.s.* ERG Code 3H, Flammable liquid, n.o.s.* (, Isopropyl alcohol solution), 3, PG 15. REGULATORY INFORMATION The preparation is classified as dangerous in accordance with Directive 1999/45/EC. Labelling Contains Symbol(s). F - Highly flammable. Xn - Harmful. R-phrase(s) R11 - Highly flammable. R36 - Irritating to eyes. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. Page 6 / 7

7 S-phrase(s) S 7 - Keep container tightly closed. S 9 - Keep container in a well-ventilated place. S16 - Keep away from sources of ignition - No smoking. S23 - Do not breathe gas/fumes/vapour/spray. S35 - This material and its container must be disposed of in a safe way. S36/37 - Wear suitable protective clothing and gloves. International Inventories Chemical Name EINECS ELINCS TSCA DSL NDSL PICCS ENCS China AICS KECL Isopropyl alcohol Present X - X X X X KE T X - X X X X KE OTHER INFORMATION Text of R phrases mentioned in Section 2 R11 - Highly flammable. R36 - Irritating to eyes. R67 - Vapours may cause drowsiness and dizziness. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. Issuing date Revision Date Revision Note 20-Apr Jun-2007 No information available Disclaimer The information provided on this SDS is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered as a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other material or in any process, unless specified in the text. End of Safety Data Sheet Page 7 / 7