TraceCERT. CRM Solutions for ICP, AAS and IC. Certified Standard Solutions produced under ISO/IEC and ISO Guide 34 2 nd Edition

Transcription

1 TraceCERT CRM Solutions for ICP, AAS and IC Certified Standard Solutions produced under ISO/IEC and ISO Guide 34 2 nd Edition

2 OCRM-PRODUCTI 2 TraceCERT Traceable Certified Reference Materials TraceCERT CRMs are high accuracy standards for instrument calibration and process validation. Following lengthy cooperation with different metrological institutes, Sigma-Aldrich has built a laboratory for Certified Reference Material (CRM) production and certification in Buchs, Switzerland. Since 2007 the lab holds the highest achievable quality assurance level for CRM producers: double accreditation, as a testing lab following ISO/IEC and also as a CRM producer following ISO Guide 34. This combination is also called the Gold Standard accreditation for CRM producers. The scope of the double accreditation at the Buchs site currently includes gravimetry, density, ICP, titrimetry and high performance quantitative NMR (HP-qNMR). This range of techniques allows us to produce CRMs for a variety of applications. While this brochure is focusing on CRM solutions for AAS, ICP and Ion Chromatography, the TraceCERT product line also comprises NIST traceable organic neat CRMs for chromatography and quantitative NMR. Please learn more by visiting our webpage sigma-aldrich.com/tracecert For all TraceCERT standards we guarantee: What makes TraceCERT stand above the others? SWISS SRMS 001 ISO Guide 34 STS 490 ISO N Elemental and ion standards are available from various suppliers. Why should I buy TraceCERT certified standards? Indeed many different standards are available covering a wide range of quality, service and price. As the world s number one in supplying research chemicals and standards, Sigma-Aldrich introduced TraceCERT reference materials to underpin its leading position in terms of quality and customer convenience. What makes TraceCERT standards higher in quality? Highest quality depends on many different technical and personal skills. These CRMs are produced and certified in accordance to metrological guidelines: highest accuracy, low uncertainties and in-depth documentation are what make TraceCERT products so reliable. These solutions are traceable to at least two independent references; NIST traceability is guaranteed whenever possible. In addition, we have extensive packaging knowledge and we guarantee all certified values until the bottle is in the customer s hands. results. Our double accreditation, according to ISO/IEC and ISO Guide 34, is an explicit affirmation of our competence to produce, certify and supply certified reference materials. Our customers can count on this competence and refer to it. We know: Buying analytical standards is a matter of trust. What about the price? These highest quality CRMs are competitively priced when compared to the products of other CRM manufacturers. When you check our website at sigma-aldrich.com/tracecert you will see that highest quality is not necessarily the most expensive ISO 9001 What is the value of Sigma-Aldrich s double accreditation to the customer? Reliability! Every analytical laboratory will demonstrate the correctness of its measurement results. The use of accurate and well-documented standards is, therefore, the first step to achieving correct measurement

3 Manufacturing of Inorganic CRMs 3 The most accurate approach for the production of standards is high-precision weighing. Under ISO Guide 34 there is a particular focus on the quality of the starting materials and the entire manufacturing process including the choice of optimal packaging. Copper Silver Tin the starting materials is assigned by the 100% minus impurities approach. Both approaches must lead to the same value within the range of their uncertainties. All starting materials are pretreated by surface etching or drying before they go to the high precision weighing room. Gravimetric preparation using pure materials is practical and the most accurate realization of concentration units. Highprecision weighing is a key step of the production, leading to direct traceability to the SI unit kilogram. The use of ultramicro balances with readability down to 100 ng in combination with a specially designed weighing room leads to maximum accuracy. Gold Silicium Cobalt Only materials of highest purity are used for the production of TraceCERT standards. The starting materials are characterized by two different approaches: the direct measurement of the purity by the most accurate method (e.g. titrimetry or high-precision ICP-OES). These measurements are compared to an internationally accepted reference material (i.e. NIST, BAM). In addition the purity of The weighed starting materials are dissolved in ultrapure acids or bases and then precisely diluted with ultrapure water to the final concentration. Also this operation is performed gravimetrically to achieve highest precision. Homogenization of the solution is achieved by overhead tumbling of the container for several hours. In the final bottling step, contamination is prevented by working under clean room conditions and by using PTFE-tubing and an inert peristaltic pump. After bottling, every batch is then compared to a second (whenever possible independent) reference material. Only when calculation and measurements are matching within their uncertainties (usually within %) the batch is released for certification.

4 4 Manufacturing of Organic IC Solutions The task of establishing traceability for organic compounds is most efficiently solved by 1 H quantitative NMR (qnmr). As a relative primary method, the big advantage of qnmr is the fact that the signal intensity of the integrals is in direct proportion to the number of hydrogen atoms leading to the signal. The chemical structure of the compound has no influence on the signal intensity. This allows for comparing different compounds quantitatively with high precision. Therefore, a small set of NIST traceable standards is sufficient to certify basically any organic compound. In other words, the direct response of a qnmr experiment is of highest accuracy, leading to certified values with low uncertainties. With a few exceptions (like sodium oxalate where the compound carries no protons), the starting materials for our IC standard solutions of organic analytes are all certified by qnmr. The certified bulk material is transferred into a 60L PVDF container by high precision weighing and dissolved with high-purity water (specific conductivity of 0.2 μm filtered) until the calculated mass of the final solution is reached. Equal to the inorganic standards, the solution is then homogenized by overhead tumbling of the container. After that, the final bottles are filled with solution under clean-room conditions using PTFE-tubing and a peristaltic pump. solution solution data for

5 This certificate is designed in accordance with ISO Guide 31 [1]. Fluka product no.: (Lot BCBF7434V) Composition: TraceSELECT and water TraceSELECT Ultra, 18.2 MΩ. cm, 0.22 μm filtered) -3 Density at 20 C: ρ = kg m uc(ρ) = 0.5 kg m-3 Intended use: Calibration of ICP-spectrometry, AAS, spectrophotometry or any other analytical technique Storing and handling: This reference material shall be stored in the original closed bag between 5 C and 30 C. After opening the bottle should be stored at reduced temperature to minimize transpiration rate. Before every use of the material the bottle must be shaken well and its temperature has to be 20 C. We highly recommend using this reference material no longer than 15 months after the aluminum bag was opened. Expiry date: JUN / 2015 (unopened bottle in aluminized bag) Bottle opening date: Certified value traceable to SI unit kg and uncertainty according to ISO Guide 35 [2] and Eurachem/CITAC Guide [3] Constituent Certified value at 20 C [4] Expanded uncertainty [U = k. uc ; k = 2] certified reference material three independent procedures were followed. The values have to agree in the range of their uncertainties, but the impurity corrected value from the gravimetric preparation has been chosen as certified value [5] : 1. Gravimetric preparation using pure materials is a practical realization of concentration units, through conversion of masses and mole fraction to mass fraction [5]. If the purity of the materials is demonstrated and if contamination and loss of material is strictly prevented this approach allows highest accuracy and small uncertainties. The certified value of TraceCERT reference materials is based on this approach and directly traceable to the SI unit kilogram. Therefore comprehensively characterized materials of highest purity are used (see paragraph 2). All balances are certified by DKD and calibrated with OIML Class E2 (up to 12 kg) and F2 (up to 64 kg) weights. The bulk solution was homogenized by overhead tumbling in a PVDF container for at least 6 hours. A peristaltic pump with perfluorinated polymer tubings was used for bottling. Detailed information about the long-term stability of the bottled solution is given in paragraph 5 of this certificate. 2. The starting material is measured against a certified reference material (i.e. NIST, BAM or EMPA) followed by gravimetric preparation using balances calibrated with SI-traceable weights. Consequently the value calculated by this unbroken chain of comparisons is traceable to the reference to which the starting material is compared. 3. Whenever applicable the bottled TraceCERT calibration solution is compared to a second reference (e.g. from NIST, BAM or EMPA) which is independent from the first reference. Sigma-Aldrich Production GmbH, Industriestrasse 25, 9471 Buchs/Switzerland, Certificate page 1 of 3 Tel , Fax , fluka@sial.com The storage behavior of standard solutions is of greatest importance with regard to the certified value. Therefore the two most important effects were investigated by in-depth studies in a cooperation with EMPA, St. Gallen: The leach out of trace impurities from HD-PE bottles was determined with HR- ICP-MS after leaching the bottles with 2% nitric acid. Maximum contamination levels were found in the ng L -1 level for 30 C 12 elements To avoid significant loss of mass Bottle stored through transpiration the bottle is without Al-bag delivered in aluminum coated bags After the bottle has been removed from the bag, transpiration will occur at an 23 C accelerated rate (see figure). We highly recommend not to open the bag until the Bottle stored solution is needed. Once the bottle is in Al-bag, 23 C opened the solution should be stored at reduced temperature (4 C) to reduce transpiration Years and reported as combined expanded uncertainties at the 95% confidence level. For gravimetric preparation the uncertainty contributions are illustrated by the following cause-effect diagram [6] : mass of starting material weighing determined value impurities buoyancy non detected correction impurities buoyancy homogeneity correction weighing solvent quality value mass of dilution and batch solution homogenization -1 Typical contributions: u(msm) < 0.01% u(mbatch) < 0.01% u(psm) < 0.05% u(hom) < 0.03% u(store) < 0.09 % u(ρ) < 0.05% Combined uncertainty [7] : uc(ccert) < 0.1% Expanded uncertainty: U(ccert) < 0.2% Certification laboratory Certification body Date of release Quality systems J. Wuethrich K.-D. Schmidt, Ph.D. July 25, 2011 SRMS 001 STS ISO Guide 34 ISO ISO 9001 Certificate page 3 of 3 purity starting material determination of density bottle leaching transpiration storing behavior certified concentration Sigma-Aldrich Production GmbH, Industriestrasse 25, 9471 Buchs/Switzerland, Tel , Fax , fluka@sial.com For high purity materials (P >99.9%) the most appropriate way of purity determination is to quantify the impurities (w i ) and to subtract the sum from 100%. Impurities below the detection limit are considered with a contribution of half of the detection limit (DL j ). DL Water containing materials were dried to absolute dryness by individual drying conditions (up to 600 C). When drying is impossible due to decomposition water was determined by high-precision KF-titration under supervision of H. Hoffmann at Sigma-Aldrich Laborchemikalien, Seelze (Germany). Water TraceSELECT Ultra (18.2 MΩ. cm; 0.22 μm filtered, all metallic traces at ng kg -1 -level) and acid in TraceSELECT quality was used for preparation. Up to 75 trace impurities were determined with ICP-OES, ICP-MS, AAS and wet chemical methods. Some of the impurities are determined in the starting material and calculated for the solution (e.g. for rare earth elements contamination during the preparation is rendered impossible). Other elements are determined both in the starting material as well as in the bottled solution. All values listed below are given in mg kg -1 (ppm), <X = below detection limit, m = matrix, n.a. = not analyzed: Li Be B C N O F Ne <0.020 <0.005 <0.020 n.a. n.a. n.a. n.a. n.a. Na Mg Al Si P S Cl Ar <0.050 <0.005 <0.010 <0.005 <0.02 <0.02 n.a. n.a. K Ca Sc Ti V Cr Mn Fe Co Ni Cu Zn Ga Ge As Se Br Kr <0.001 <0.020 <0.001 <0.005 <0.010 <0.050 <0.005 <0.020 <0.010 <0.010 < <0.001 <0.050 <0.002 <0.01 n.a. n.a. Rb Sr Y Zr Nb Mo Tc Ru Rh Pd Ag Cd In Sn Sb Te I Xe <0.001 <0.005 <0.001 <0.010 <0.001 <0.050 n.a. < <0.001 <0.001 <0.005 <0.001 < <0.001 n.a. n.a. Cs Ba La Hf Ta W Re Os Ir Pt Au Hg Tl Pb Bi Po At Rn <0.001 <0.005 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.005 m <0.03 <0.001 <0.050 <0.050 <0.001 n.a. n.a. n.a. Fr Ra Ac n.a. n.a. n.a. Ce Pr Nd Pm Sm Eu Gd Tb Dy Ho Er Tm Yb Lu <0.001 <0.001 <0.001 n.a. <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 Th Pa U <0.001 n.a. <0.001 Only internationally accepted reference materials e.g. from NIST (USA), BAM (Germany) or EMPA Material Science & Technology (Switzerland) have been carefully selected to provide the basis for traceability to the SI unit mole. When no such reference is available, an elemental metal or an adequate salt of highest available purity is used to confirm traceability to this pure material (and therefore to the SI unit kg). To underpin the certified gravimetric value all traceability measurements are performed with the most accurate and precise analytical technique available. Therefore titrimetry measurement series are applied whenever possible (corrected for trace impurities). When no titrimetric technique is available, the traceability measurements are performed with another analytical technique, e.g. ICP-OES or AAS. Reference and applied technique used for traceability measurements of the starting material: NIST SRM 3140 / ICP-OES Reference and applied technique used for traceability measurements of the bottled solution: NIST SRM 3140 / ICP-OES Certificate page 2 of 3 Sigma-Aldrich Production GmbH, Industriestrasse 25, 9471 Buchs/Switzerland, Tel , Fax , fluka@sial.com Certification and Comprehensive Documentation 5 For each TraceCERT product, a detailed and comprehensive certificate of up to four pages is supplied, either delivered with the product (for the ICP standards) or downloadable from the Internet using product number and lot number (for the AAS and IC standards). Example certificates for every product can be downloaded from the Internet (sigma-aldrich.com/tracecert). The certificates are in accordance with ISO Guide 31. Below you see an example of a certificate for a platinum ICP standard highlighting the most important features. 1 2 Lot Specific Content Including Uncertainties: Certified value traceable to SI unit kg and uncertainty according to ISO Guide 35 [2] and Eurachem/CITAC Guide [3] Constituent Certified value at 20 C [4] Expanded uncertainty [U = k. uc ; k = 2] Platinum 1000 mg L mg L 976 mg kg -1 2 mg kg -1 Certified values are reported as mass per volume and as mass per mass. Uncertainty budgets are obtained by summing up all the contributing influence parameters ( bottom-up approach) and are illustrated by a cause-effect diagram: mass of starting material (msm) weighing value buoyancy correction buoyancy correction weighing value mass of batch solution ( m Batch ) purity starting material (P SM ) determined impurities non detected impurities homogeneity solvent quality dilution and homogenization (Hom) determination of density ( ρ ) bottle leaching transpiration storing behavior ( Store ) certified concentration ( c cert ) Typical contributions: u(msm) < 0.01% u(mbatch) < 0.01% u(psm) < 0.05% u(hom) < 0.03% u(store) < 0.09 % u(ρ) < 0.05% Combined uncertainty [7] : uc(ccert) < 0.1% Expanded uncertainty: U(ccert) < 0.2% Object of certification: Platinum standard for ICP Platinum metal (high purity quality) in 5% HCl (prepared from HCl TraceSELECT, HNO3 Platinum 1000 mg L -1 2 mg L 976 mg kg -1 2 mg kg CONCEPT OF CERTIFICATION AND TRACEABILITY STATEMENT To guarantee top reliability of the values for this TraceCERT 5. STORING BEHAVIOR Increase of concentration relative to gl UNCERTAINTY EVALUATION All uncertainties are calculated according to Eurachem/CITAC Guide [3] ( m SM ) ( m Batch ) (P SM ) (Hom) ( ρ ) ( Store ) measured (mean of 9 bottles) extrapolated Produced in double accredited laboratory fulfilling and ISO/IEC and ISO Guide Transpiration through HD-PE bottles ( c cert) 3 2. PURITY OF STARTING MATERIALS P = 100% w 3. TRACE IMPURITIES IN BOTTLED SOLUTION 4. TRACEABILITY MEASUREMENTS [1] ISO Guide 31, 1-7, 2 nd Ed. (2000), Reference materials - Contents of certificates and labels [2] ISO Guide 35, 1-64, 3 rd Ed. (2006), Reference materials - General and statistical principles for certification [3] Eurachem/CITAC Guide, 1-120, 2 nd Ed. (2000), Quantifying uncertainty in analytical measurement [4] The mg kg -1 value is the certified value whereas the mg L -1 value is calculated with the density [5] Eurachem/CITAC Guide, 1-37, 1 st Ed. (2003) Traceability in chemical measurement [6] Reichmuth, A., Wunderli, S., Weber, M., Meyer, V. R., The uncertainty of weighing data obtained with electronic analytical balances, Microchimica Acta (2004) 148: [7] Calculated by combination of the squared contribution values 3 Traceability Statement Reference and applied technique used for traceability measurements of the starting material: NIST SRM 3140 / ICP-OES Reference and applied technique used for traceability measurements of the bottled solution: NIST SRM 3140 / ICP-OES 5 Expiration Date: Expiry date: JUN / 2015 (unopened bottle in aluminized bag) 4 Trace Impurities in Bottled Solution* Up to 75 trace impurities, determined with ICP-OES, ICP-MS, AAS and wet chemical methods. Li Be B C N O F Ne <0.020 <0.005 <0.020 n.a. n.a. n.a. n.a. n.a. Na Mg Al Si P S Cl Ar <0.050 <0.005 <0.010 <0.005 <0.02 <0.02 n.a. n.a. K Ca Sc Ti V Cr Mn Fe Co Ni Cu Zn Ga Ge As Se Br Kr <0.001 <0.020 <0.001 <0.005 <0.010 <0.050 <0.005 <0.020 <0.010 <0.010 < <0.001 <0.050 <0.002 <0.01 n.a. n.a. Rb Sr Y Zr Nb Mo Tc Ru Rh Pd Ag Cd In Sn Sb Te I Xe <0.001 <0.005 <0.001 <0.010 <0.001 <0.050 n.a. < <0.001 <0.001 <0.005 <0.001 < <0.001 n.a. n.a. Cs Ba La Hf Ta W Re Os Ir Pt Au Hg Tl Pb Bi Po At Rn <0.001 <0.005 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.005 m <0.03 <0.001 <0.050 <0.050 <0.001 n.a. n.a. n.a. Fr Ra Ac n.a. n.a. n.a. Ce Pr Nd Pm Sm Eu Gd Tb Dy Ho Er Tm Yb Lu <0.001 <0.001 <0.001 n.a. <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 <0.001 Th Pa U <0.001 n.a. <0.001 *This is only reported for the ICP standard solutions. For the IC standard solutions, trace impurities of the most relevant ions are given 6 7 Bottle opening date: Density: ρ = kg m -3 u c (ρ) = 0.5 kg m -3 Signatures and Accreditation Stamps Certification laboratory Certification body Date of release Quality systems J. Wuethrich K.-D. Schmidt, Ph.D. July 25, 2011 SRMS 001 STS ISO Guide 34 ISO ISO 9001

6 6 Packaging and Stability The ideal container for standard solutions is totally inert, i.e., will not absorb the analyte, does not leach impurities into the solution, is impermeable to the solvent and atmosphere, is easy to handle and affordable. For TraceCERT standards we have developed the most suitable container fulfilling all of these criteria: the HDPE bottle. These bottles are extensively tested for leaching of impurities and the loss of weight by transpiration of the solvent was also investigated comprehensively as shown in the diagram below. The results of this study are also stated in the certificate of each TraceCERT product. For maximum shelf life, the bottles for ICP standards are sealed in aluminum bags to further prevent transpiration. Only this special packaging makes it possible to guarantee the ambitious specification of 0.2% uncertainty over the entire shelf life. In the case of organic IC Standards, the HDPE bottles are x-ray sterilized and the bottled solution is additionally stabilized with sodium azide (about 5 mg/l) and filtered through a 0.2 μm membrane. Transpiration Through HDPE Bottle

7 TraceCERT Product Portfolio The TraceCERT product line of ICP, AAS and IC standard solutions actually comprises over 200 products. Since we are continuously expanding the product range, we also recommend consulting our website at sigma-aldrich.com/tracecert. In addition to our broad catalog offering, we also offer custom standards (see page 11) mg/l Single Element Standard Solutions for AAS and ICP AAS standards are supplied in 250 ml HDPE bottles (with some exceptions). Shelf life of these products is usually 3 years. The certificate can be downloaded from the Internet using product number and lot number. Element (1000 mg/l) Composition ICP standards are supplied in HDPE bottles and sealed in an aluminum bag. We can, therefore, guarantee an expiry of up to 4 years for the ICP standards. The printed certificate is delivered with the product. Cat. No. AAS Standard Package Size Cat. No. ICP Standard Package Size Aluminum Al(NO 3 ) 3 x 9H 2 O + nitric acid ml Antimony Sb metal + nitric acid (+ hydrofluoric acid traces) ml Arsenic As 2 O 3 + nitric acid (+ NaOH for AAS) ml Barium BaCO 3 + nitric acid ml Berylium Be acetate + nitric acid ml Bismuth Bi metal + nitric acid ml Boron H 3 BO 3 + water ml Cadmium Cd metal + nitric acid ml Calcium CaCO 3 + nitric acid ml Cerium CeO 2 + nitric acid ml Cesium CsNO 3 + nitric acid ml Chromium Cr(NO 3 ) 3 + nitric acid ml Cobalt Co metal + nitric acid ml Copper Cu metal + nitric acid ml Dysprosium Dy 2 O 3 + nitric acid Erbium Er 2 O 3 + nitric acid Europium Eu 2 O 3 + nitric acid Gadolinium Gd 2 O 3 + nitric acid Gallium Ga metal + nitric acid Germanium Ge semi-metal + nitric acid (hydrofluoric acid traces) ml ml Gold Au metal + hydrochloric acid (nitric acid traces) Hafnium Hf metal + nitric acid (hydrofluoric acid traces) ml Holmium Ho 2 O 3 + nitric acid Indium In metal + nitric acid Iron Fe metal + nitric acid ml Lanthanum La 2 O 3 + nitric acid Lead Pb(NO 3 ) 2 + nitric acid ml Lithium Li 2 CO 3 + nitric acid ml Lutetium Lu 2 O 3 + nitric acid Magnesium Mg metal + nitric acid ml Manganese Mn metal + nitric acid ml Mercury Hg metal + nitric acid Molybdenum Mo metal + hydrochloric acid + (nitric acid traces) ml Neodymium Nd 2 O 3 + nitric acid Nickel Ni metal + nitric acid ml Niobium Nb metal + nitric acid (hydrofluoric acid traces) Palladium Pd metal + hydrochloric acid (nitric acid traces) Phosphorus H 3 PO 4 + water ml Platinum Pt metal + hydrochloric acid (nitric acid traces)

8 8 Element (1000 mg/l) Composition Cat. No. AAS Standard Package Size Cat. No. ICP Standard Package Size Potassium KNO 3 + nitric acid ml Rhodium RhCl 3 + hydrochloric acid Rubidium RbNO 3 + nitric acid Scandium Sc 2 O 3 + nitric acid Selenium Se metal + nitric acid ml Silicon Si metal + NaOH ml Silicon Si metal + nitric acid + hydrofluoric acid Silver Ag metal + nitric acid ml Sodium NaNO 3 + nitric acid ml Strontium Sr(NO 3 ) 2 + nitric acid ml Sulfur H 2 SO 4 + water ml Tantalum Ta metal + nitric acid (hydrofluoric acid traces) Tellurium Te semi-metal + nitric acid + hydrofluoric acid ml Terbium Tb 2 O 3 + nitric acid Thallium TINO 3 + nitric acid Thulium Tm 2 O 3 + nitric acid Tin Sn metal + hydrochloric acid ml Titanium Ti metal + nitric acid Tungsten W metal + nitric acid (hydrofluoric acid traces) Vanadium V 2 O 5 + nitric acid ml Yttrium Y 2 O 3 + nitric acid ml Zinc Zn metal + nitric acid ml Zirconium Zr metal + nitric acid + hydrofluoric acid ml ,000 mg/l Single Element Standard Solutions for AAS and ICP Element (10,000 mg/l) Composition Cat. No. Package Size Aluminum Al(NO 3 ) 3 x 9H 2 O + nitric acid Antimony Sb metal + nitric acid + hydrofluoric acid Boron H 3 BO 3 + ammonium hydroxid solution Cadmium Cd metal + nitric acid Calcium CaCO 3 + nitric acid Cesium CsNO 3 + nitric acid Chromium Cr(NO 3 ) 3 + nitric acid Cobalt Co metal + nitric acid Copper Cu metal + nitric acid Iron Fe metal + nitric acid Lead Pb(NO 3 ) 2 + nitric acid Magnesium Mg metal + nitric acid Manganese Mn(NO 3 ) 2 x 4H 2 O + nitric acid Nickel Ni metal + nitric acid Palladium Pd metal + hydrochloric acid (nitric acid traces) Phosphorous H 3 PO 4 + water Potassium KNO 3 + nitric acid Sodium NaNO 3 + nitric acid Sulfur H 2 SO 4 + water Tin Sn metal + nitric acid + hydrofluoric acid Titanium Ti metal + nitric acid + hydrofluoric acid Tungsten W metal + nitric acid + hydrofluoric acid Vanadium V metal + nitric acid Yttrium Y 2 O 3 + nitric acid Zinc Zn metal + nitric acid 68961

9 Multielement Standards for ICP 9 All our multielement standard solutions are delivered in HDPE bottles (except for the USP mixes, which are delivered in FEP (Fluorinated Ethylene Propylene) bottles), sealed in an aluminium bag and the printed certificate is delivered with the product. Periodic Table Mixes With these three multielement standard solutions, all ICP measurable elements of the periodic table are covered (excluding mercury). All components are present at a concentration of 10 mg/l. Li Na K Rb Be Mg Ca Sc Ti V Sr Y Zr Nb Cr Mo Mn Tc Fe Ru Co Rh Ni Pd B Al Cu Ag Zn Cd Ga In C Si Ge Sn N P As Sb O S Se Te F Cl Br l Ne Ar Kr Xe Cs Ba La Hf Ta W Re Os Ir Pt Au Hg Tl Pb Bi Po At Rn Fr Ra Ac Ce Pr Nd Pm Sm Eu Gd Tb Dy Ho Er Tm Yb Lu Th Pa U Cat. No. Description Composition Matrix Package Size Periodic Table Mix 1 for ICP 33 elements (10 mg/l each) 10% nitric acid Periodic Table Mix 2 for ICP 18 elements (10 mg/l each) 5% hydrochloric acid and 1% hydrofluoric acid Periodic Table Mix 3 for ICP 16 elements (10 mg/l each) 5% nitric acid Chemical Group Mixes Each of these eight multielement standard solutions contains a specific group of elements. Concentrations of the analytes are 100 mg/l except for the rare elements mix where the analytes have a concentration of 50 mg/l. Li Na K Rb Cs Be Mg Ca Sr Ba Sc Y La Ti Zr Hf V Nb Ta Fr Ra Ac Cr Mo W Mn Tc Re Fe Ru Os Co Rh Ir Ni Pd Pt B C N Al Si P Cu Ag Zn Cd Ga In Ge Sn As Sb O F S Cl Se Br Te l Au Hg Tl Pb Bi Po At Ne Ar Kr Xe Rn Ce Pr Nd Pm Sm Eu Gd Tb Dy Ho Er Tm Yb Lu Th Pa U Cat. No. Description Composition Matrix Package Size Alkali Metal Mix for ICP 5 elements (100 mg/l each) 2% nitric acid Alkaline Earth Metal Mix for ICP 5 elements (100 mg/l each) 2% nitric acid Rare Earth Metal Mix for ICP 16 elements (50 mg/l each) 2% nitric acid Metalloid and Non-Metal Mix for ICP 10 elements (100 mg/l each) 10% nitric acid and <0.5% hydrofluoric acid Post-transition Metal Mix for ICP 6 elements (100 mg/l each) 2% nitric acid Transition Metal Mix 1 for ICP 10 elements (100 mg/l each) 2% nitric acid and 1% hydrofluoric acid Transition Metal Mix 2 for ICP 8 elements (100 mg/l each) 2% nitric acid Transition Metal Mix 3 for ICP 7 elements (100 mg/l each) 5% nitric acid Other ICP Mixes Cat. No. Description and Composition Package Size Multielement standard solution I for ICP (in 10 % HNO 3 ) Ag, Ba, Ca, Cd, Co, Cu, Fe, Mg, Mn, Sr, Zn: 10 mg/l each Al, B, Cr, Li, Mo, Na, Ni, Tl: 50 mg/l each Bi, K, Pb: 100 mg/l each Multielement standard solution III for ICP (in 5 % HNO 3 ) K: 200 mg/l Mg: 400 mg/l Na: 1000 mg/l Ca: 2000 mg/l Multielement standard solution IV for ICP (in 10 % HNO 3 ) Cr, Cu, Ni: 20 mg/l each Al, As, Ba, Pb, V: 40 mg/l each B, Fe, Se, Tl, Zn: 100 mg/l each Be, Cd, Co, Mn: 10mg/L each Multielement standard solution V for ICP (in 10 % HNO 3 ) Ag, Al, Ba, Be, Bi, Cd, Co, Cr, Cs, Cu, Ga, In, Li, Mg, Mn, Mo, Ni, Pb, Rb, Sr, Tl, V, Zn: 10 mg/l each Ca, Fe, Ca, Na:100 mg/l each

10 mg/l Single Ion Standards for IC All IC standards are supplied in HDPE bottles. As a unique feature for these IC standards we list the most common trace impurities that are relevant for the IC separation. Inorganic Anions (1000 mg/l) Composition Cat. No. Package Size Bromide NaBr + water Chloride NaCl + water Chromate K 2 CrO 4 + water Cyanide K 2 Zn(CN) 4 + water Fluoride NaF + water Iodide KI + water Nitrate NaNO 3 + water Nitrate Nitrogen NaNO 3 + water Nitrite NaNO 2 + water (NaOH stabilized) Nitrite Nitrogen NaNO 2 + water (NaOH stabilized) Phosphate Na 2 HPO 4 + water Sulfate Na 2 SO 4 + water Organic Anions (1000 mg/l) Composition Cat. No. Package Size Acetate Acetic acid, NaOH, water Adipate Adipic acid + water Benzoate Benzoic acid, water Butyrate Sodium butyrate, water Citrate Citric acid, water Formate Calcium formate, water Glutarate Glutaric acid + water Glycolate Glyolic acid + water Lactate Magnesium L-lactate + water Malate L-( )-Malic acid + water Maleate Maleic acid, water Malonate Malonic acid, water Oxalate Sodium oxalate, water Phthalate Potassium phthalate monobasic, water Propionate Sodium propionate, water Succinate Succinic acid + water Tartrate L-( + )-Tartaric acid, water Inorganic Cations (1000 mg/l) Composition Cat. No. Package Size Ammonium NH 4 Cl + water Ammonium (Nitrogen) NH 4 Cl, water Barium BaCO 3 + nitric acid Cadmium Cd metal + nitric acid Calcium CaCO 3 + nitric acid Cobalt Co metal + nitric acid Copper Cu metal + nitric acid Lead Pb(NO 3 ) 2 + nitric acid Lithium Li 2 CO 3 + nitric acid Magnesium Mg metal + nitric acid Manganese Mn metal + nitric acid Nickel Ni metal + nitric acid Potassium KNO 3 + water Sodium NaNO 3 + water Strontium Sr(NO 3 ) 2 + nitric acid Zinc Zn metal + nitric acid 67902

11 11 Multiion Standards for IC All Standards are packaged in a HDPE bottle. The starting materials for the two PRIMUS primary multiion standards were certified by EMPA (Eidgenössische Materialprüfungs- und Forschungsanstalt) and BAM (Bundesamt für Materialforschung und -prüfung, Germany). Multiion Standards Description and Composition Package Size Primary Multi Anion Standard Solution (PRIMUS), certified for ion chromatography, Reference 50 ml material traceable to SI, 10.0 mg/kg ± 0.2% F -, Cl , NO 3-, PO 4, SO 4 each anion Primary Multi Cation Standard Solution (PRIMUS), certified for ion chromatography, Reference material traceable to SI, 10.0 mg/kg ± 0.2% Li +, Na +, K +, Mg 2+, Ca 2+ each cation Multi Cation Standard 1 for IC, Ca: 1000 mg/l; K: 200 mg/l; Li: 50 mg/l; Mg: 200 mg/l; Na: 200 mg/l 50 ml In addition to our comprehensive portfolio of catalog products, we also offer you a custom service where you can define your own multi-component standards using our Inorganic Custom Standards Online Platform: It s easy! Try it out!

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