Welcome to the unique world of Chemelot Campus. Frank Schaap

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1 Welcome to the unique world of Chemelot Campus Frank Schaap November 14 th 2012

2 What is Chemelot? One of the largest chematerial communities in Europe (> 800 ha) Industrial Park + Campus Number of companies on site > 100; 70 new companies since 2005 Many of them global leaders in their product market combination jobs on Chemelot; approx visitors per day Industrial Park Sharing infrastructure and costs Campus Sharing knowledge and global networks

3 Chemelot, many global leaders

4 What is Chemelot? Eindhoven Aachen Brussels Maastricht

5

6 Chemelot Campus Three shareholders: triple helix Dutch Province of Limburg DSM Nederland Maastricht University/Maastricht UMC+ Common goal: Growth of regional economy by accelerated growth of Chemelot Campus

7 Chemelot ambition A globally recognized chematerials valley offering accelerated business growth for all parties involved > 3!

8 Unique strengths Advanced (bio) organic chemistry Performance Materials Process technology Analytical support

9 BioMedical Materials Unique strengths BioBased Materials Advanced (bio) organic chemistry Micro reactor technology Performance Materials Process technology Analytical support

10 Chemelot Campus focus sectors Performance Materials Biobased Chemicals and Materials Biomedical Materials Biosynthesis R&D Enabling Technologies

11 70 new members of Chemelot Community (since 2005) Start up s Small Medium Enterprises (SME s) Multinationals: Manufacturing and/or R&D Knowledge Institutes (Universities, Technical High Schools) Public Private Partnership programs Service providers

12 Chemelot Campus development base case scenario Onderwijs en kennisinstellingen Nieuwe Campus bewoners vanaf 2011 Bestaande Campus bewoners (niet DSM) DSM spin off's en divestments Service boulevard DSM R&D

13 Change in time 2012 to 2020

14 Real Estate Developments, example 1 DSM Materials Science Center Completion Date: Labs and offices R&D and Sales offices 420 FTE 14 Developments

15 Real Estate Developments, example 2 Lanxess headquarter building Completion Date: Labs and offices R&D and Sales offices 120 FTE (ca. 25 from Leverkusen) Lanxess HTE installation Completion Date: Labs and offices in FTE 15 Developments

16 Value Creation by Open Innovation 1a Market Scouting / Business Intelligence 1 Fuzzy Front End 1c. Interaction / Synthesis 2 Joint Business Developments 3 R&D services 4a Licensing In 5 Venturing 4b Licensing Out 6a Spin in 7a Acquisitions Open innovation is no longer a competitive advantage It has become a competitive necessity! 7b 6b Divestments Spin out 1b Competence Development, Technology Intelligence 8 Intellectual Asset Management

17 Open innovation at Chemelot Start up SME

18 Open innovation at Chemelot Start up SME

19 EXAMPLES > 3!

20 Unique strengths BioBased Materials Advanced (bio) organic chemistry Performance Materials Process technology Analytical support

21 Innovation happens naturally, ask Avantium...

22 Avantium Technology company (IP) Spin-off from Royal Dutch Shell in 2000 Proven expertise in catalysis research & technology Development of biobased materials and fuels 130 employees Based in Amsterdam, expanding to Chemelot Listed in the Guardian Cleantech Top 100 World player Avantium customer base:

23 BioBased materials valuechain BioMaterial products BioBased Chemicals and Fuels BioPolymers Polymerization Fermentation Compounding Formulation Carbon Source & other renew. Fermentation/ Chemical conversion Unique Fermentation combination of biotech and materials market know-how

24 Pilot plant goals 1. Product for application development 2. Optimal process conditions 3. Select the best catalysts 4. Select equipment 5. Scale up data 6. Durability

25 Strategic Joint Development Partnerships

26 Why did Avantium select Chemelot? Strong fit with chemistry, processing and new materials community Access to unique existing infrastructure Availability of service and support providers Human capital (operators, engineers, specialists) Possibility to go to larger scale and commercial production

27 Unique strengths BioMedical Materials Advanced (bio) organic chemistry Performance Materials Process technology Analytical support

28 DSM Biomedical - open innovation approach External Licensing Mergers & Acquisitions Venturing Professor Tony Mikos (Rice University, Houston, USA) Dr. Ivo Buschmann (Charité, University of Medicine, Berlin and Freiburg University, Germany), Mr. Patrick Cahalan, BSc (Ension Inc., Pittsburgh, USA) Scientific Advisory Board Internal development Chemelot Campus BioMedical Materials Program

29 Strategic pathway DSM Biomedical Coatings and Implants Polymerenabled anddrug Implants Coatings delivery Coatings Polymer Regenerative enabled anddrug Medicine Implants delivery MagnaMedics

30 Innovation happens naturally, ask TiGenix

31

32

33 TiGenix, Why Chemelot? Biomedical materials and regenerative medicine activities and business development focus (DSM Biomedical, Magnamedics, Interface BIOmaterials, Cellmade, Bio Medical Materials Program.) Triple helix focus on regenerative medicine (regional governments, knowledge institutes and companies) Tailor made training program for cleanroom operators Central location in Western Europe Logistics Environmental permit Availability of fit for use space and infrastructure Chemelot s community Adequate financing of 5,4 mln for GMP cel expansion manufacturing facility (LIOF, Limburg Ventures, Particon, LRM)

34 Open innovation = collaboration between people Open innovation = people working together 34

35 Goals and Roles Chemelot Campus organization Growth by hunting Attract new tenants Generate new tenants (valorization) Attract investments of existing tenants Growth by farming Community building connecting people Cluster development Service boulevard (real estate, business, R&D and general services) Place to be for talented students and employees

36 Chemelot Campus community diversity potential Material Sciences and Life Sciences Global business leaders and Knowledge Institutes Global networks and Regional networks Professional corporate culture and entrepreneurial start up culture Business mindset and students Academic, HBO and MBO students and teachers Triple helix representatives Challenge: How to maximize synergy by social innovation?

37 Unlocking present unique know-how at Chemelot Campus is KSF Strategic Groups in Campus arena Industry nucleus creates business mindset Academic nuclues creates accessibility of knowledge By introducing academic context at Chemelot Campus, we introduce sharing culture being critical element for Open Innovation Ecosystem. Chemelot Campus Campus with same focus area NL top Campusses Expected move Business Mindset HTC CC Oss GCC Zwoll e MHC Technopolis Delft Bioscience Leiden WUR A dam Science Park Twente Aachen Science Park 3 7 Accessible unique know-how

38 Chemelot Chemelot, one of the most innovative chematerials communities in Europe Chemelot designed to accelerate business growth through sharing of know-how, infrastructure and networks Chemelot creates added value for the companies involved, their customers and suppliers and the region Chemelot, a community of winners!

39

40 Chemelot Interested to relocate your business? Frank Schaap Director Marketing & Business Development

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