Stem Cell Patents: An Analysis

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1 Stem Cell Patents: An Analysis Antoinette F. Konski, Esq. Partner, Foley & Lardner, LLP Doris Spielthenner Partner and Vice President, FAS.research February 2008 Attorney Advertising Prior results do not guarantee a similar outcome Models used are not Data Analysis Delphion Database The INPADOC collection provides over 30 million patent family documents from 71 patent offices worldwide, and 45 million legal status actions from 42 worldwide patent offices. INPADOC is the most comprehensive database in which to perform patent family searches on a worldwide basis, and is estimated to cover 95% of all patents published since Attorney Advertising Prior results do not guarantee a similar outcome Models used are not

2 Analysis Methodology Network Analysis Identifies relationships between literature, authors, assignees and patents Patent Importance or Dominance One measure is the number of later filed patents/applications that reference the patent or application, see Bergman & Graff (2007) The global stem cell patent landscape: implications for efficient technology transfer and commercial development, Nature Biotechnology, Vol. 25(4):419 Search Query Search Query: stem cells in the claims Approximately 8,000 patents identified 288 patents identified as important based on crossreferencing Attorney Advertising Prior results do not guarantee a similar outcome Models used are not

3 Clusters Issue/publication dates 1980s to to to 2008 Subject Matter Adult or somatic stem cells Embryonic stem cells: Human and non-human Stem Cell Citation Trees Main component of stem cell citation trees Strong lines between two patents indicates the patents are highly referenced by each other and others Attorney Advertising Prior results do not guarantee a similar outcome Models used are not

4 Citation Tree 70ies 90ies 2000 till Citation Tree - Dates 70ies 90ies 2000 till Attorney Advertising Prior results do not guarantee a similar outcome Models used are not

5 Research Clusters A1 Manipulating stem cells/protein markers B1 embryonic C1 Non-human stem cell research Culturing hematopoietic stem cells A2 B2 Culturing neural stem cells 70ies 90ies 2000 till Cluster A1 Manipulating stem cells/protein markers Attorney Advertising Prior results do not guarantee a similar outcome Models used are not

6 Cluster A2 Culturing hematopoietic stem cells Cluster B1 B1 Attorney Advertising Prior results do not guarantee a similar outcome Models used are not

7 Cluster B2 Cluster C1 C1 Non-human stem cell research Attorney Advertising Prior results do not guarantee a similar outcome Models used are not

8 Center Cluster Top 25 Patents - Bridging patents - Patents linking the most various fields of stem cell research Attorney Advertising Prior results do not guarantee a similar outcome Models used are not

9 No. 1 No. 2 Attorney Advertising Prior results do not guarantee a similar outcome Models used are not

10 Conclusions No significant shift from US patents to non-us patents after 2005 May be too early to see trends From , adult stem cell research remained strong based on early 80 s/90 s patent filings Few embryonic stem cell patents prior to 2005 Embryonic stem cell patents appear to bridge non-human embryonic stem cell and adult stem cell patents Contact Information Antoinette F. Konski Foley & Lardner, LLP akonski@foley.com Doris Spielthenner FAS.research doris.spielthenner@fas-research.com Attorney Advertising Prior results do not guarantee a similar outcome Models used are not

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