BIOMARKERS - ADVANCED TECHNOLOGIES AND GLOBAL MARKET ( )
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1 BIOMARKERS - ADVANCED TECHNOLOGIES AND GLOBAL MARKET ( ) R e p o r t D e s c r i p t i o n T a b l e o f C o n t e n t s L i s t o f T a b l e s S a m p l e T a b l e s R e l a t e d R e p o r t s A b o u t M a r k e t s a n d M a r k e t s MarketsandMarkets Research 108 West 13th Street, Wilmington, DE 19801, County of New Castle Tel. No.:
2 Report Description The Global Biomarker Market report analyzes the biomarker tools and services market over the period The report studies the major market drivers, restraints, and opportunities for the global biomarker market; and also evaluates the major trends in the macroand micro-markets with respect to different geographic regions. The global biomarker market is estimated to be $20.5 billion by 2014, growing at a CAGR of 19.7 % from 2009 to 2014, driven by the high demand for the biomarkers in the field of drug discovery. The markets for biomarker tools and services are expected to grow at a CAGR of 18.5% and 22.2% respectively. The increasing use of biomarkers in clinical services is boosting the overall biomarker service market. The high growth of biomarker market is boosted by the demand from the baby boomer generation in the U.S., and from Asia s emerging IT industry. Biomarker applications are increasing in cancer diagnosis as novel tools are being developed to increase the discovery speed of cancer biomarkers. The use of proteomics in biomarker testing and identification has in turn boosted the services for the biomarkers. Market players are now focusing on new product and service development to enhance their commercial portfolios. Strategic collaborations among companies are also increasing biomarker applications in the field of diagnosis and drug discovery. Scope and format The report analyzes the global biomarker market into the following segments: Tools Market (pregenomic biomarkers and technologies, postgenomic biomarkers and technologies, imaging biomarkers, and others) Services Market (pre- and post-clinical biomarker services, sample preparation, mirna analysis, and others) Application Market (diagnosis, and drug development and discovery) The market data consists of aggregate sales figures of all biomarker submarkets. It analyzes the market aspects of new biomarker technologies and product launches; sourcing key market developments from the top companies that it profiles. The report also analyzes the documented claims and the biomarker technology patents approved over the last five years to provide an in-depth understanding of biomarker tools and services. 2
3 Table of Contents 1. Introduction 1.1 Key take aways 1.2 Report description 1.3 Markets covered 1.4 Stakeholders 2. Market overview 2.1 Defining Biomarker 2.2 Defining The Biomarker Market 2.3 Biomarker Applications In Diagnosis and Drug Discovery 2.4 Applications In Cardiovascular and Cancer Diagnosis 2.5 Pre- and Post-clinical Biomarker Services 2.6 Biomarker Patent Analysis 3. Summary 4. Biomarker Market Dynamics 4.1 Drivers High Initial Investment Hinders Biomarker Applicability High Demand For Biomarkers In Drug Discovery Biomarker Tests Perceived As Unreliable Biomarkers Aid The Early Detection Of Drug Approval Of Diagnostic Tools For Biomarkers Failures Biomarker Validation Approaches Still Not Biomarkers As Cancer Diagnostic Tools Clearly Addressed Cro Recognize Value Of Biomarkers In Drug Lack Of Web-based Solutions For Biomarker Development Discovery Developments In Proteomics and Genomics 4.3. Opportunities Fda Support For Biomarker Development Translational Medicine Focus On Biomarker 4.2 Restraints Accurate and Precise Diagnosis Regulatory Environment Restrains Market Commercial Applications In Proteomics Growth 5. Global Biomarker Tools Market 5.1 Drivers Diagnosis Introduction Of Cancer Biomarkers and Molecular Diagnostics Advanced Informatics Drivers 5.2 Pre-genomic Biomarkers and Technologies Automated molecular techniques and Drivers technology developments Biomarker Discovery Stimulates Immunodiagnostics Technology Development Drivers & Restraints Molecular Diagnostics Facilitates Quick Immunoassays aid early disease 3
4 Table of Contents detection and timely diagnosis Rapid Growth of Metabolomics Data Price erosion and lack of standardization Analysis Solutions hinder market growth d Gel Electrophoresis Enzyme and Metabolite Assays Differential In-gel Electrophoresis 5.3. Post-genomic Biomarkers and Technologies Transcriptomics 5.4. Drivers Positional Dna Microarrays High Demand for Medical Technologies Encoded Particle Arrays Greater Stress on Individual Risk Analysis Of Metabolites In Biological Assessment Specimens 5.5. Restraints & Opportunities Disease-related Biomarkers High Cost of Genomics Platform Metabolite Profiling For Biomarker Emerging Field of Nutrition Research Discovery Proteomics Imaging Biomarkers Drivers Drivers Proteomics Enhances the Efficiency Increasing Use Of Imaging Biomarkers and Speed of Drug Discovery In Drug Development Proteomics Aids Personalized Therapy Imaging Biomarkers Also Used In Development Disease Analysis Restraints Molecular Imaging Expensive Proteomics Analysis Tools Magnetic Resonance Imaging Leads to Low Adoption Rates Positron Emission Tomography Need To Speed Up The Validation Fdg-pet Patient Phase I Studies Process Imaging Biomarkers As Study Endpoints Mass Spectrometry In Biomarker Discovery and Validation Other Biomarker Tools Drivers Bioinformatics Metabolomics Protein Microarrays Drivers DNA Microarray Metabolomics Spurs the Drug Antibody Microarrays Development Process Reagents 6. Global Biomarker Services Market 6.1. Drivers Blood/biofluids Emergence Of Cro s As Service Providers Cell Lines Eukaryotic and Prokaryotic High Roi From Investment In Biomarker Frozen/rnalater/rnaretain Tissues Discovery 6.5. Other Services 6.2. Biomarker Pre- and Post-clinical Services Bioinformatics Services Biomarker Testing Data Analysis Assay Development Mrna Analysis 6.3. Antibody Development 6.6. Mirna Analysis Validation and Reporting Mirna Microarray Service 6.4. Sample Preparation Mirna Expression Profiling 4
5 Table of Contents 7. Global Biomarker Applications Market 7.1. Drivers Biomarkers Provide Effective Treatment and Demand For Predictive Technologies Diagnosis Technology Developments Boost Demand for Neurological Diseases Biomarkers 7.6. Drivers & Restraints Biomarkers Facilitate the Development of Alzheimer s disease Safer Drugs Image-based biomarkers 7.2. Restraints Genetic markers Biomarkers May Generate Erroneous End Biomarkers in blood Points Biomarkers in cerebrospinal fluid Large Varieties Of Biomarkers Delay Evaluation Schizophrenia Ethical Issues Regarding Patient Rights Parkinson s Disease 7.3. Diagnosis Tuberculosis Cancer Diagnosis 7.7. Drivers Drivers Biomarkers Accelerate Tb Drug Development Ovarian Cancer Diagnostics Stroke Diagnosis Her2 Breast Cancer Diagnostics 7.8. Drivers Bladder Cancer Incidence Of Stroke Increasing Globally Cervical Cancer Diagnostics 7.9. Drug Development & Discovery Prostate Cancer Drug Targets Cardiovascular and Metabolic Diseases Target Validation 7.4. Drivers Target Discovery Cardiovascular Biomarkers Can Accurately Predict Heart Failure Biomarkers Enhance Diagnosis Of Metabolic Lead Identification Target Discovery Using Functional Genomics Disease Adme-tox Profiling Autoimmune and Inflammatory Diseases Drug Development and Process Quality Assurance 7.5. Drivers 8. Geographic Analysis Of Biomarker Market 8.1. North America 8.2. Europe 8.3. Asia 8.4. Row 9. Competitive Landscape 5
6 Table of Contents 10. Company Profiles Affymetrix Ingenuity Systems Agilent Technologies Insilicos Amgen Integromics Ariadne Mds Inc Banyan Biomarkers Inc Metabolon Inc Bg Medicine Metanomics Health Gmbh Biophysical Corp Microdiscovery Biosystems International (bsi) Molecular Connections Calibrant Nanogen Caprion Proteomics Nextgen Group Plc Correlogic Systems Inc Nonlinear Usa Inc Cyclacel Nuvera Biosciences Decode Ocimum Biosolutions Epigenomics Pam Gene Bv Exagen Diagnostics Inc Partek GE Healthcare Pronota Genedata Perlegen Genego Phenomenome Discoveries Inc Genenews Siemens Healthcare Gyros Ab Singulex Human Metabolome Technologies (hmt) Softgenetics Llc Illumina Inc Tyrian Imgenex Zeptosens Inforsense Appendix 1. United States Patents 2. Europe Patents 3. Japan Patents 6
7 List of Tables Summary Table Global Biomarker Market by Tools and Services Global Metabolite Profiling For Bio Marker Discovery Market by Geography Global Bio Marker Tools Market by Product Global Imaging Biomarkers Market by Product Global Bio Marker Tools Market by Geography Global Imaging Biomarkers Market by Geography Global Pregenomic Biomarkers and Technologies 27 Global Molecular Imaging Market by Geography 2007 Market by Product Global Pregenomic Biomarkers and Technologies 28 Global Magnetic Resonance Imaging Market by Market by Geography Geography Global Molecular Diagnostics Market by Product Global Positron Emission Tomography Market by Geography Global Molecular Diagnostics Market Bygeography 30 Global Fdg-pet Patient Phase I Studies Market by Geography Global Immunodiagnostics Market by Geography Global Imaging Bio Markers As Study Endpoints Market by Geography Global Enzyme and Metabolite Assays Market 32 Global Others Market by Product Bygeography Global Post Genomic Bio Markers and Technologies 33 Global Others Market by Geography Market by Product Global Post Genomic Bio Markers and Technologies 34 Global Bioinformatics Market by Geography Market by Geography Global Proteomics Market by Product Global Reagents Market by Geography Global Proteomics Market by Geography Global Biomarker Services Market by Product Global Mass Spectrometry In Bio Marker Discovery and 37 Global Bio Marker Services Market by Geography 2007 Validation Market by Geography Global Biomarker Pre and Post Clinical Services Market 14 Global Metabolomics Market by Geography by Product Global Biomarker Pre and Post Clinical Services Market 15 Global 2d Gel Electrophoresis Market by Geography by Geography Global Biomarker Testing Market by Geography Global Differential In-gel Electrophoresis Market by Geography Global Assay Development Market by Geography Global Transcriptomics Market by Product Global Antibody Development Market by Geography 18 Global Transcriptomics Market by Geography Global Validation and Reporting Market by Geography 19 Global Positional Dna Microarrays Market by Geography Global Sample Preparation Market by Product Global Encoded Particle Arrays Market by Geography Global Sample Preparation Market by Geography Global Analysis Of Metabolites In Biological Specimens Market by Product Global Blood/bio Fluids Market by Geography Global Analysis Of Metabolites In Biological Specimens 2014 Market by Geography Global Cell Lines Eukaryotic and Prokaryotic Market 23 Global Disease-related Biomarkers Market Bygeography by Geography
8 List of Tables 48 Global Frozen/rnalater/rnaretain Tissues Market by 61 Global Neurological Disease Market by Product 2007 Geography Global Other Services Market by Product Global Alzheimer s Disease Market by Product Global Other Services Market by Geography Global Drug Development and Discovery Market by Product Global Bioinformatics Services Market by Geography 64 Global Drug Target Market by Product Global Data Analysis Market by Geography Global Target Validation Market by Product Global Mrna Analysis Market by Geography North American Biomarker Market Global Mirna Analysis Market by Product European Biomarker Market Asian Biomarker Market Global Mirna Analysis Market by Geography Row Biomarker Market New Product, Technology, Service Launch ( ) 56 Global Mirna Microarray Service Market by Geography Agreements and Collaborations ( ) 57 Global Mirna Expresion Profiling Market by Geography Global Biomarker Applications Market Global Diagnosis Market by Product Global Cancer Diagnosis Market by Product List of Figures 1 Biomarker Discovery 15 Imaging Biomarkers Applications In Drug 2 Evolution Of Biomarkers and Future Shift Development 3 Biomarker Market Segmentation 16 Bioinformatics Microarrays For Biomarker Discovery 4 Business Architecture 17 Biomarker Areas In Drug Development Process 5 Biomarker Opportunity 18 Global Biomarker Market By Geography 6 Biomarker Challenges 19 Global Biomarker Tools Market By Geography 7 Biomarker Applications Market Prospective 20 Global Biomarker Service Market By Geography 8 Biomarker Applications Market Dynamics 21 Geography-wise Biomarker Market- Global Perspective 9 Biomarker Services Market Dynamics 22 Major Segments In The Global Biomarker Market 10 Patent Analysis By Technology 2006 To Competitive Landscape For Strategy Formation 11 Patent Analysis By Company ( ) ( ) 12 Patent Analysis By Geography 13 Biomarker Clinical Trial Effectiveness 14 Biomarker Applications In Molecular Diagnostics 8
9 Global Biomarker Market Biomarker tools (Hardware & Software) Service market Global Biomarker Applications Market Diagnosis Drug development and discovery Global Biomarker Market by geography North America Europe Asia Rest of the World Sam pletables Biomarker Tool Providers Pregenomic Biomarkers and Technologies Postgenomic Biomarkers and Technologies Imaging Biomarkers Others 9
10 Pregenomic Biomarkers and Technologies Enzyme and Metabolite Assays Immunodiagnostics Molecular Diagnostics Postgenomic Biomarkers and Technologies Transcriptomics Proteomics Analysis of Metabolites in Biological Specimens Imaging Biomarkers Molecular Imaging Magnetic Resonance Imaging Positron Emission Tomography FDG-PET Patient Phase I Studies Imaging Biomarkers as Study Endpoints Others Reagents Bioinformatics Sampl e Tables 10
11 Biomarker service providers Biomarker Pre and Post Clinical Services Sample Preparation mirna Analysis Others Sam pletables Biomarker Pre and Post Clinical Services Antibody Development Assay Development Validation and Reporting Assay Production Biomarker Testing Sample Preparation Cell lines eukaryotic and prokaryotic Blood/biofluids Frozen/RNAlater/RNAretain tissues Fixed (FFPE) tissues mirna Analysis mirna Expression Profiling mirna Microarray Service 11
12 Others Bioinformatics Services MRNA Analysis DNA Analysis Data Analysis Sam pletables Biomarker Applications Diagnosis Drug Development & Discovery Diagnosis Cancer Diagnosis Stroke Diagnosis Neurological Diseases Cardiovascular and Metabolic Diseases Tuberculosis Autoimmune and Inflammatory Diseases Drug Development & Discovery Drug Targets ADME-TOX profiling Drug development and process quality assurance 12
13 Key Questions What Makes Our Report Unique? Provision of longest market segmentation in the industry. The report provides analysis of patents and more than 45 company profiles giving a competitive outlook. The report includes market data for segments such as tools, services and applications for the major geographies U.S., Europe, Asian and ROW. The high level analysis provided by the report analyzes the market prospective for different major market segments along with the identification of opportunities. Provided competitive analysis stating the major segments focused by the global market players and the key developments tools, services and technology. Key Questions Answered Which are the high growth markets segments in terms of tools, services and applications? What are the market forecasts and estimates from the period ? What are the major drivers and opportunities in the market? What is the competitive outlook, what are the major tools and services, who are the major players in the market segments? 13
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15 About MarketsandMarkets We publish about 120 reports a Our clients value our reports year across 10 main industries. especially for the market insight The reports are exhaustive, we provide along with the market detailing about 50 micro markets n u m b e r s. O u r t e a m s o f and product segments, and specialized market analysts and featuring about 80 to 100 market domain experts work within a data summary tables, 50 short structured research process to company profiles, a five-level deliver well-analyzed market market breakdown, overviews of r e p o r t s t o F o r t u n e more than 300 patents, as well as companies globally. analyses of the strategic and competitive landscape. Click here to learn more about us Related Reports Global Biomaterial Market ( ) For the past 100 years, biomaterials have been used in the human body to improve the body functions and replace the damaged tissues of the body. These materials have been evolved from inert biomaterials to biodegradable biomaterials that can be dissolved in the body. Advances in technology and emergence of innovative products have enhanced the performance and applications of these biomaterials. Report code: BT 1026 Price: $4650 Global Biosimilars Market ( ) Biosimilars report will provide indepth market assessment, market estimates and forecast, competitive landscape for the series of biosimilars- Erythropoeitins, Granulocyte Colony Stimulating Factors, Market, HGH, Insulin and Analogs, Interferons. Report code: BT 1030 Price: $4650 Global Injectable Drug Delivery Market In addition to the market size, data trends and forecasts, the report will also highlight key opportunity areas for the relevant stakeholders. We will analyze new product launches. In addition, we will analyze and profile key market developments of the top companies in this market and its sub-segments while drawing a competitive landscape for major markets and their sub segments. Report code: BT 1113 Price: $
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