Separation Systems for Commercial Biotechnology. Shalini S. Dewan. Report # BIO011G

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1 Separation Systems for Commercial Biotechnology Shalini S. Dewan Report # BIO011G

2 Table of Contents Chapter 1 Introduction... 1 Introduction... 2 Study goals and objectives... 2 Reasons for doing this study... 2 Contributions of the study and for whom... 2 Scope of report... 3 Information sources... 3 Methodology... 3 Analyst s credentials... 3 Related BCC Research reports... 4 Geographic breakdown... 4 Chapter 2 Summary and Highlights... 7 Summary and highlights... 8 Chapter 3 Overview Overview Introduction History of biotechnology Classification of biomolecular separation systems in biotechnology Chromatography Membrane filtration Centrifugation Electrophoresis Flow cytometry New methods of biomolecular separations Microarray Lab on a chip Biochip Magnetic separation Molecular classes of biomolecular separation Protein DNA Antibodies Hormones End users of biotechnology separation systems Chapter 4 New Developments New developments Mergers and acquisitions Chapter 5 Market Analysis Market analysis Market by type Market overview Market revenue Chromatography... 40

3 Centrifugation Electrophoresis Membrane filtration Flow cytometry Magnetic separation Microarray Biochip Lab on a chip Market by region Chromatography Centrifugation Electrophoresis Membrane filtration Flow cytometry Magnetic separation Microarrays Biochips Lab on a chip Chapter 6 Industry Structure Industry structure Chromatography Liquid chromatography Thin layer chromatography Centrifugation Ultracentrifugation Lower speed, high speed and micro centrifugation Electrophoresis Gel electrophoresis Capillary electrophoresis Membrane filtration Market leaders Market shares Flow cytometry Market leaders Market shares Magnetic separation Market leaders Market shares Microarrays Market leaders Market shares Biochip Market leaders Market shares Lab on a chip Market leaders Market shares Chapter 7 Patent Analysis Patent analysis

4 Patents by year Patents by type Patents by company Patents by country Patents by assignee Chapter 8 Current Situation Current situation Factors affecting bioseparation system market Drivers Restraints and challenges Market opportunities Chapter 9 Company Profiles Company profiles M Company Abaxis Inc Abtech Scientific Inc Agilent Technologies Inc Alfa Laval Group Alfa Wassermann Separation Technologies Arrayit Corp BD BioSciences (Becton, Dickinson and Company) Biocept Inc Biodot Inc BioMerieux SA Bio Rad Laboratories Inc Boston Microfluidics Camag Scientific Inc Combimatrix Molecular Diagnostics Inc Customarray Inc Danaher Corp Beckman Coulter Inc Pall Corp Sciex DNAmicroarray Inc Falcon Genomics Inc Flottweg Separation Technology GE Healthcare Life Sciences GEA Westfalia Separator Group GmbH GWC Technologies Hitachi Koki Co. Ltd Illumina Inc Immunovia AB Luminex Corp Merck KGaA Miltenyi Biotec Inc Microarray Inc Nanostring Technologies Inc Novasep Inc PerkinElmer

5 Qiagen Gmbh Randox Laboratories Ltd Sartorius Corp Shimadzu Scientific Instruments Spectrum Chemical Manufacturing Corp Sysmex Partec Gmbh Thermo Fisher Scientific US Biomax Inc Waters Corp W. R. Grace & Company Appendix Abbreviations Abbreviations Lists of Tables and Figures About BCC Research About BCC Research... Error! Bookmark not defined. Conditions of purchase Report Subscriptions Custom Analyses... Error! Bookmark not defined.

6 Lists of Tables and Figures Separations Systems for Commercial Biotechnology 155

7 List of Tables TABLE 1 Summary Table: Global market for bioseparation, through 2021 ($ millions)... 9 TABLE 2 History of biotechnology TABLE 3 Classes of filtration by pore size TABLE 4 New product launches in biomolecular separation systems from leading manufacturers, 2012 May TABLE 5 Mergers and acquisitions of biomolecular separation system companies, TABLE 6 Global market for bioseparation, by type, through 2021 ($ millions) TABLE 7 Global market for chromatography, by type, through 2021 ($ millions) TABLE 8 Global market for centrifugation, by type, through 2021 ($ millions) TABLE 9 Global market for electrophoresis, by type, through 2021 ($ millions) TABLE 10 Global market for membrane filtration, through 2021 ($ millions) TABLE 11 Global market for flow cytometry, through 2021 ($ millions) TABLE 12 Global market for magnetic separation, through 2021 ($ millions) TABLE 13 Global market for microarrays, through 2021 ($ millions) TABLE 14 Global market for biochips, through 2021 ($ millions) TABLE 15 Global market for lab on a-chip, through 2021 ($ millions) TABLE 16 Global market for liquid chromatography by region, through 2021 ($ millions) TABLE 17 Global market for thin layer and flash chromatography, by region, through 2021 ($ millions) TABLE 18 Global market for ultracentifugation, by region, through 2021 ($ millions) TABLE 19 Global market for low-speed, high-speed and micro-centrifugation, by region, through 2021 ($ millions) TABLE 20 Global market for gel-electrophoresis, by region, through 2021 ($ millions) TABLE 21 Global market for capillary electrophoresis, by region, through 2021 ($ millions) TABLE 22 Global market for membrane filtration, by region, through 2021 ($ millions) TABLE 23 Global market for flow cytometry, by region, through 2021 ($ millions) TABLE 24 Global market for magnetic separation, by region, through 2021 ($ millions) TABLE 25 Global market for microarrays, by region, through 2021 ($ millions) TABLE 26 Global market for biochips, by region, through 2021 ($ millions) TABLE 27 Global market for lab-on-a-chip, by region, through 2021 ($ millions) TABLE 28 Leading manufacturers/suppliers of liquid chromatography, TABLE 29 Global market shares for manufacturers of liquid chromatography, 2015 (%) TABLE 30 Leading manufacturers or suppliers of thin layer chromatography, TABLE 31 Global market shares for manufacturers of thin layer chromatography, 2015 (%) TABLE 32 Leading manufacturers or suppliers of ultracentrifugation, TABLE 33 Global market shares of manufacturers of ultracentrifugation, 2015 (%) TABLE 34 Leading manufacturers or suppliers of lower speed, high speed and micro centrifugation, TABLE 35 Global market shares of manufacturers of lower speed, high speed and micro centrifugation, 2015 (%) TABLE 36 Leading manufacturers of gel electrophoresis, TABLE 37 Global market shares for manufacturers of gel electrophoresis, 2015 (%) TABLE 38 Leading manufacturers of capillary electrophoresis, TABLE 39 Global market shares for manufacturers of capillary electrophoresis, 2015 (%) Separations Systems for Commercial Biotechnology 156

8 TABLE 40 Leading manufacturers of membrane filtration, TABLE 41 Global market shares for manufacturers of membrane filtration, 2015 (%) TABLE 42 Leading manufacturers of flow cytometry, TABLE 43 Global market shares for manufacturers of flow cytometry, 2015 (%) TABLE 44 Leading manufacturers of magnetic separation, TABLE 45 Global market shares of manufacturers of magnetic separation, 2015 (%) TABLE 46 Leading manufacturers of microarrays, TABLE 47 Global market shares for manufacturers of microarrays, 2015 (%) TABLE 48 Leading manufacturers of biochips, TABLE 49 Global market shares for manufacturers of biochips, 2015 (%) TABLE 50 Leading manufacturers of lab on a chip, TABLE 51 Global market shares for manufacturers of lab on a chip, 2015 (%) TABLE 52 Number of patents approved for separation system equipment by year, 2012 May TABLE 53 Number of patents approved for separation system equipment by type, 2012 May TABLE 54 Number of patents approved for separation system equipment by company, 2012 May TABLE 55 Number of patents approved for separation system equipment by country, 2012 May TABLE 56 Patent shares by country, January 2012 May 2016 (%) TABLE 57 Number of patents by assignee, 2012 May Separations Systems for Commercial Biotechnology 157

9 List of Figures FIGURE 1 Summary Figure: Global market for bioseparation, ($ millions)... 9 FIGURE 2 Global market for bioseparation, by type, ($ millions) FIGURE 3 Global market for chromatography, by type, ($ millions) FIGURE 4 Global market for centrifugation, by type, ($ millions) FIGURE 5 Global market for electrophoresis by type, ($ millions) FIGURE 6 Global market for membrane filtration, ($ millions) FIGURE 7 Global market for flow cytometry, ($ millions) FIGURE 8 Global market for magnetic separation, ($ millions) FIGURE 9 Global market for microarrays, ($ millions) FIGURE 10 Global market for biochips, ($ millions) FIGURE 11 Global market for lab-on-a-chip, ($ millions) FIGURE 12 Global market for liquid chromatography, by region, ($ millions) FIGURE 13 Global market for thin layer and flash chromatography, by region, ($ millions).. 60 FIGURE 14 Global market for ultracentrifugation, by region, ($ millions) FIGURE 15 Global market for low-speed, high-speed and micro-centrifugation, by region, ($ millions) FIGURE 16 Global market for gel-electrophoresis, by region, ($ millions) FIGURE 17 Global market for capillary electrophoresis, by region, ($ millions) FIGURE 18 Global market for membrane filtration, by region, ($ millions) FIGURE 19 Global market for flow cytometry, by region, ($ millions) FIGURE 20 Global market for magnetic separation, by region, ($ millions) FIGURE 21 Global market for microarrays, by region, ($ millions) FIGURE 22 Global market for biochips, by region, ($ millions) FIGURE 23 Global market for lab-on-a-chip, by region, ($ millions) FIGURE 24 Global market shares for manufacturers of liquid chromatography, 2015 (%) FIGURE 25 Global market shares for manufacturers of thin layer chromatography, 2015 (%) FIGURE 26 Global market shares of manufacturers of ultracentrifugation, 2015 (%) FIGURE 27 Global market shares for manufacturers of lower speed, high speed and micro centrifugation, 2015 (%) FIGURE 28 Global market shares for manufacturers of gel electrophoresis, FIGURE 29 Global market shares for manufacturers of capillary electrophoresis, 2015 (%) FIGURE 30 Global market shares for manufacturers of membrane filtration, 2015 (%) FIGURE 31 Global market shares for manufacturers of flow cytometry, 2015 (%) FIGURE 32 Global market shares for manufacturers of magnetic separation, 2015 (%) FIGURE 33 Global market shares for manufacturers of microarrays, 2015 (%) FIGURE 34 Global market shares for manufacturers of biochips, 2015 (%) FIGURE 35 Global market shares of manufacturers of lab on a chip, 2015 (%) FIGURE 36 Number of patents approved for separation system equipment by year, 2012 May FIGURE 37 Number of patents approved for separation system equipment by type, 2012 May FIGURE 38 Number of patents approved for separation system equipment, 2012 May FIGURE 39 Number of patents approved for separation system equipment by country, 2012 May FIGURE 40 Patent shares by country, January 2012 May 2016 (%) FIGURE 41 Number of patents by assignee, 2012 May Separations Systems for Commercial Biotechnology 158

10 About BCC Research Separations Systems for Commercial Biotechnology 159

11 About BCC Research With our unparalleled 45-year history, BCC Research provides comprehensive analysis of global market sizing, forecasting and industry intelligence, covering markets where advances in science and technology are improving the quality, standard and sustainability of businesses, economies and lives. BCC Library Access From market sizing and forecasts, to opportunity assessments and competitive analyses, our everexpanding library gives you the data, insights and intelligence required to ensure your project is a success. With myriad options for access to fit all needs and budgets, call or info@bccresearch.com to request a demo. BCC Custom Research Our experts provide custom research projects to those working to identify new markets, introduce new products, validate existing market share, analyze competition and assess the potential for products to impact existing markets. With impressive academic credentials and broad and deep knowledge of global industrial markets, our independent analysts and consultants develop the facts, figures, analysis and assessments to inform the decisions that will move your company ahead. Confidential inquiries to: custom@bccresearch.com or Separations Systems for Commercial Biotechnology 160

12 ISBN: March 2017 Separations Systems for Commercial Biotechnology 161

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