Sysmex CS-2500 Hemostasis System Unrestricted Siemens Healthcare Diagnostics Inc All rights reserved.

Size: px
Start display at page:

Download "Sysmex CS-2500 Hemostasis System Unrestricted Siemens Healthcare Diagnostics Inc All rights reserved."

Transcription

1 Excel with Confidence Sysmex CS-2500 Hemostasis System Unrestricted Siemens Healthcare Diagnostics Inc All rights reserved.

2 General Lab Challenges Test Volume Financial Performance Accuracy Reliability Budget Competition Diagnostic errors Page 2

3 Hemostasis Lab Challenges Others Incorrect samples Underfilling Sample dilution and prolonged clotting 2 Preanalytical errors and unsuitable samples account for Lippi G, Banfi G, Buttarello M, et al. Clin Chem Lab Med. 2007;45(6): Favaloro E, Lippi G, Adcock D. Semin Thromb Hemost. 2008;34: Lippi G, Blanckaert N, Bonini P, et al. Clin Chem Lab Med. 2008;46(6): Favaloro EJ, Lippi G, Funk (Adcock) D. Labmedicine Feb;43(2). Hemolyzed samples up to Insufficient samples 70% of lab errors. 1 Hemolytic Negatively affects medical care 3 Icteric Requires photometric detection 1 Lipemic Affects clotting factor activity 4 Page 3

4 Hemostasis Lab Challenges Focus on PSI checks to identify issues Around 15% of cases have an impact on patient care 4 Improve workflow efficiency, TAT, accuracy, and quality of results Major impact on laboratory processes 4. Favaloro EJ, Lippi G, Funk (Adcock) D. Labmedicine Feb;43(2). Page 4

5 Sysmex CS-2500 System Assay-based HIL checks using PSI technology Automated mixing studies Automated platelet aggregation * Clot waveform analysis Take hemostasis testing to the next level. Excel with confidence. *Sysmex CE-marked application. Research use only. Page 5

6 Sysmex CS-2500 System Simultaneous multiwavelength PSI technology Wide spectrum of analysis methods on one analyzer 24 touchscreen with Windows 7-based software Seamless integration across labs Take hemostasis testing to the next level. Excel with confidence. Page 6

7 Sysmex CS-2500 System Confidence Consistency Capacity Operational Efficiency Uninterrupted Workflow Page 7

8 Sysmex CS-2500 System Confidence Page 8

9 Consolidated Multipurpose Instrument Assay-based HIL checks using PSI technology Automated mixing studies Automated platelet aggregation* Clot waveform analysis Save space Reduce cost Increase flexibility *Sysmex CE-marked application. Research use only. Page 9 Confidence Consistency Capacity Efficiency Workflow

10 Automated Mixing Studies Quicker, more efficient workflow Seconds Target 1:1 dilution Target 1:1 dilution Tested plasma % Page 10 Confidence Consistency Capacity Efficiency Workflow

11 Sysmex CS-2500 System Consistency Page 11

12 Consistent Processing Controls Controls Controls Calibrators Each system uses the same Calibrators controls, calibrators, and assays. Calibrators Assay and reference ranges Assay and reference ranges Assay and reference ranges Consumables Reagents Consumables Each system uses the same reagents and consumables. Reagents Consumables Reagents Sysmex CA-600 System Sysmex CS-2500 System Sysmex CS-5100 System Sysmex CA-600 Systems cuvettes are an exception. Page 12 Confidence Consistency Capacity Efficiency Workflow

13 Sysmex CS-2500 System Capacity Page 13

14 Number of samples Clotting Chromogenic Immunoturbidimetric Aggregation Expansive Test Menu Sysmex CS-2500 System Capacity Sysmex CS-2500 System Range Requests Standard test offering PT, APTT, Fibrinogen, Thrombin Time, Batroxobin Time, Protein C, Protein S, APC Resistance, Factor V Leiden Factor Deficiency, Lupus Anticoagulant Heparin, Protein C, Antithrombin III, α2-antiplasmin, Plasminogen, C1-Inhibitor, Coagulation Factor XIII and Factor VIII Requests D-Dimer, Von Willebrand factor, Free Protein S von Willebrand Factor, ADP, Epinephrine, Ristocetin, Collagen, Arachidonic acid Number of tests Under development. Not available for sale. The future availability of this feature cannot be guaranteed. Page 14 Confidence Consistency Capacity Efficiency Workflow

15 Sysmex CS-2500 System Operational Efficiency Page 15

16 Easily Accessible Information Reagent information values for controls, calibrators, standards, and PT reagents ISI values 10,000 samples 60 results per sample Windows 7 Greater productivity Sample results search McAfee embedded control 24 wide-screen LCD display with touch operation Page 16 Confidence Consistency Capacity Efficiency Workflow

17 Intuitive System Interface Intuitive user interface Easy-to-adjust screen format when viewing results Streamline lab operations and maximize your productivity Page 17 Confidence Consistency Capacity Efficiency Workflow

18 Real-time System Control Single-screen monitoring of reagent and consumable levels Automated quality control functions INNER OUTER Streamline lab operations and maximize your productivity. Comprehensive onboard help Page 18 Confidence Consistency Capacity Efficiency Workflow

19 Fully Traceable Results Maintenance and QC history Easy-to-use audit trails Results Up to 100 users Trace actions per user User-unique login Page 19 Confidence Consistency Capacity Efficiency Workflow

20 Sysmex CS-2500 System Uninterrupted Workflow Page 20

21 Clotting Chromogenic Immunoturbidimetric Aggregation Flexible Sampling Capabilities Flexible vial-type management Sysmex CS-2500 System Up to 40 reagents and five additional buffer positions Third-generation cappiercing technology Anti-evaporation caps minimize waste Page 21 Confidence Consistency Capacity Efficiency Workflow

22 Longer Lasting Reagents and Reduced Dead Volume Reagent probe Flat vial 5 ml Reagent probe Tilted vial Sample probe 1 ml 16% For lowvolume controls and calibration reagents (1 ml) 800 µl 300 µl 6% 150 µl Page 22 Confidence Consistency Capacity Efficiency Workflow

23 Simple Maintenance Procedures Less than 5 minutes of daily maintenance Only 10 minutes of weekly/monthly maintenance Recorded at the touch of a button Traceable maintenance User-defined tasks Minimize downtime. Page 23 Confidence Consistency Capacity Efficiency Workflow

24 Sysmex CS-2500 System Confidence Consistency Capacity Operational Efficiency Uninterrupted Workflow Page 24

DEPARTMENT OF CLINICAL LABORATORY SCIENCES SCHOOL OF HEALTH TECHNOLOGY AND MANAGEMENT THE UNIVERSITY AT STONY BROOK STONY BROOK, NEW YORK

DEPARTMENT OF CLINICAL LABORATORY SCIENCES SCHOOL OF HEALTH TECHNOLOGY AND MANAGEMENT THE UNIVERSITY AT STONY BROOK STONY BROOK, NEW YORK DEPARTMENT OF CLINICAL LABORATORY SCIENCES SCHOOL OF HEALTH TECHNOLOGY AND MANAGEMENT THE UNIVERSITY AT STONY BROOK STONY BROOK, NEW YORK 11794-8205 COAGULATION COMPETENCY EVALUATION FORM STUDENT NAME:

More information

Session 1 Topics. Vascular Phase of Hemostasis. Coagulation Pathway. Action of Unfractionated Heparin. Laboratory Monitoring of Anticoagulant Therapy

Session 1 Topics. Vascular Phase of Hemostasis. Coagulation Pathway. Action of Unfractionated Heparin. Laboratory Monitoring of Anticoagulant Therapy ~~Marshfield Labs Presents~~ Laboratory Monitoring of Anticoagulant Therapy Session 1 of 4 Session 1 Topics Review of coagulation and the vascular phase of hemostasis Unfractionated heparin Low molecular

More information

INNOVANCE DTI Assay Delivering the Reliability Your Lab Needs to Confidently Test for Dabigatran

INNOVANCE DTI Assay Delivering the Reliability Your Lab Needs to Confidently Test for Dabigatran Eva-Maria Landmann Marketing Manager Hemostasis INNOVANCE DTI Assay Delivering the Reliability Your Lab Needs to Confidently Test for Dabigatran INNOVANCE DTI Assay* Introduction Clinical Information Dabigatran

More information

2015 Catalogue Coagulation

2015 Catalogue Coagulation 2015 Catalogue Coagulation 1 CONTENTS Reagents TriniCLOT TM Routine Reagents PT 4 aptt 4 Fibrinogen 5 Thrombin Time 5 Factor Deficient Plasmas 5 Solutions 5 TriniLIA TM D-Dimer TriniLIA TM D-Dimer 6 TriniCLOT

More information

Table of Contents. Introduction. Worldwide Market and Technology Overview

Table of Contents. Introduction. Worldwide Market and Technology Overview Table of Contents Introduction Worldwide Market and Technology Overview A. Major Routine and Special Coagulation Tests 1. Introduction 2. Activated Partial Thromboplastin Time (APTT) 3. Alpha-2 Antiplasmin

More information

Bench top / Desktop. English HumaClot Pro GUI. Open at launch, but system will be closed mandatorily in the future.

Bench top / Desktop. English HumaClot Pro GUI. Open at launch, but system will be closed mandatorily in the future. Specifications & more HumaClot Pro > > System Specifications > > Scope of Supply > > Obligatory Items > > Optional Items System Overview Cat.No. 15800 Analyzer type Fully automated coagulation analyzer

More information

Activated Protein C Resistance vs Factor V Leiden assay: Which is the most cost effective?

Activated Protein C Resistance vs Factor V Leiden assay: Which is the most cost effective? Activated Protein C Resistance vs Factor V Leiden assay: Which is the most cost effective? Rajiv K. Pruthi, M.B.B.S Co-Director, Special Coagulation Laboratory & Director, Mayo Comprehensive Hemophilia

More information

Coagulation Laboratory: Methods, Standards & Cost Effective Testing Part 1

Coagulation Laboratory: Methods, Standards & Cost Effective Testing Part 1 Coagulation Laboratory: Methods, Standards & Cost Effective Testing Part 1 Donna D. Castellone, MS, MT (ASCP) SH Clinical Project Manager Hematology and Hemostasis Siemens Healthcare Diagnostics Disclosures

More information

Completing the performance picture.

Completing the performance picture. Completing the performance picture. AU5800 Clinical Chemistry Systems Blood Banking Centrifugation Chemistry Flow Cytometry Hematology Hemostasis Immunoassay Information Systems Lab Automation Molecular

More information

Marcia L. Zucker, Ph.D. ZIVD LLC

Marcia L. Zucker, Ph.D. ZIVD LLC Marcia L. Zucker, Ph.D. ZIVD LLC 1 Monitoring hemostasis Bleeding Clotting 2 Picture courtesy of Helena Laboratories 3 Extrinsic Pathway Monitor with ACT / aptt WARFARIN Monitor with PT Common Pathway

More information

Note: The taller 100 x 13 mm tube is not designed to run on the ACL TOP. Plasma after centrifugation of these tubes must be placed in sample cups.

Note: The taller 100 x 13 mm tube is not designed to run on the ACL TOP. Plasma after centrifugation of these tubes must be placed in sample cups. Created Revised Reviewed Approved Lupus Insensitive aptt on the ACL TOP HEM 4.15.1 7/13/2012 4/11/2013 4/11/2013 4/11/2013 I. PRINCIPLE The activated partial thromboplastin time is a global screening procedure

More information

DOAC s and Implications on Laboratory Results. Kandice Kottke-Marchant, MD, PhD Cleveland Clinic

DOAC s and Implications on Laboratory Results. Kandice Kottke-Marchant, MD, PhD Cleveland Clinic DOAC s and Implications on Laboratory Results Kandice Kottke-Marchant, MD, PhD Cleveland Clinic Anticoagulants Heparin Low Molecular Weight Heparins enoxaparin, fragmin Heparin pentasaccharide - fondaparinux

More information

Introduction Hemostasis: Tourniquet Test & Bleeding Time. Hematology-Immunology System Faculty of Medicine Universitas Padjadjaran LOGO

Introduction Hemostasis: Tourniquet Test & Bleeding Time. Hematology-Immunology System Faculty of Medicine Universitas Padjadjaran LOGO Introduction Hemostasis: Tourniquet Test & Bleeding Time Hematology-Immunology System Faculty of Medicine Universitas Padjadjaran LOGO Hemostasis A series of reactions that function to stop bleeding, maintaining

More information

True Walkaway Automated Urinalysis, Chemistry to Microscopy The CLINITEK AUWi System Answers for life.

True Walkaway Automated Urinalysis, Chemistry to Microscopy The CLINITEK AUWi System Answers for life. www.siemens.com/diagnostics True Walkaway Automated Urinalysis, Chemistry to Microscopy The CLINITEK AUWi System Answers for life. Can I achieve true unattended urinalysis testing in my laboratory? With

More information

PROTHROMBIN TIME WHY USE LOW ISI (HIGH SENSITIVITY)

PROTHROMBIN TIME WHY USE LOW ISI (HIGH SENSITIVITY) PROTHROMBIN TIME WHY USE LOW ISI (HIGH SENSITIVITY) PROTHROMBIN TIME DEFINITION The Prothrombin time is the functional determination of the extrinsic coagulation pathway. It is a widely used laboratory

More information

LABORATORY APPROACH TO BLEEDING DISORDERS DR NISHANTH PG 1 ST YEAR DEPARTMENT OF PATHOLOGY

LABORATORY APPROACH TO BLEEDING DISORDERS DR NISHANTH PG 1 ST YEAR DEPARTMENT OF PATHOLOGY LABORATORY APPROACH TO BLEEDING DISORDERS DR NISHANTH PG 1 ST YEAR DEPARTMENT OF PATHOLOGY 1 WHEN IS THE LAB REQUIRED TO INVESTIGATE FOR A POSSIBLE BLEEDING DISORDER? Clinically suspected bleeding tendency

More information

With Stago, discover an outstanding Routine range

With Stago, discover an outstanding Routine range In Haemostasis, There s routine... and then there s Routine With Stago, discover an outstanding Routine range An optimal Routine range for guaranteed satisfaction 1 Comprehensive range Stago s extensive

More information

Upon completion of the Clinical Hematology rotation, the MLS student will be able to:

Upon completion of the Clinical Hematology rotation, the MLS student will be able to: Clinical Performance Objectives in Clinical Hematology Department of Medical and Research Technology University of Maryland School of Medicine Spring 2015 Upon completion of the Clinical Hematology rotation,

More information

The Coagulation Workup In The Office Setting

The Coagulation Workup In The Office Setting CAA Conference alm Springs 2012 The Coagulation Workup In The Office Setting CAA Conference alm Springs, October 2012 Robert Miller, A-C Henoch-Schoenlein urpura 1 CAA Conference alm Springs 2012 2 CAA

More information

Laboratory Investigation of Challenging Cases. Laura A. Worfolk, Ph.D Scientific Director, Coagulation

Laboratory Investigation of Challenging Cases. Laura A. Worfolk, Ph.D Scientific Director, Coagulation Laboratory Investigation of Challenging Cases Laura A. Worfolk, Ph.D Scientific Director, Coagulation Disclosures Employee of Quest Diagnostics Case focus: Importance of knowing test limitation/interpretations

More information

Special Coagulation - APC Resistance. DiaPharma Group, Inc. Customer Service: Technical Support:

Special Coagulation - APC Resistance. DiaPharma Group, Inc. Customer Service: Technical Support: Special Coagulation - APC Resistance DiaPharma Group, Inc. Customer Service: 1.800.526.5224 Technical Support:1.800.447.3846 www.diapharma.com 1 Review of Hemostasis Overview Pathways of coagulation, anticoagulation,

More information

cobas 8100 automated workflow series 3-D intelligence in lab automation

cobas 8100 automated workflow series 3-D intelligence in lab automation 3-D intelligence in lab automation Personalized Lab Automation Maximizing Testing Efficiency and Medical Value Hospital network Commercial laboratories Independent hospitals At Roche, laboratory automated

More information

Dade Behring. Analyst Meeting July 18, Page 1

Dade Behring. Analyst Meeting July 18, Page 1 Dade Behring Analyst Meeting July 18, 2007 Page 1 Agenda Welcome / Introductions Overview Products and Solutions Update U.S. / Chemistry Spain / Microbiology Germany / Hemostasis Summary Jim Reid-Anderson

More information

OVERVIEW OF LABORATORY DIAGNOSTIC TESTING FOR PLATELET DISORDERS

OVERVIEW OF LABORATORY DIAGNOSTIC TESTING FOR PLATELET DISORDERS OVERVIEW OF LABORATORY DIAGNOSTIC TESTING FOR PLATELET DISORDERS Catherine P. M. Hayward, MD PhD, FRCP(C) Head, Coagulation, Hamilton Regional Laboratory Medicine Program Professor, Pathology and Molecular

More information

AssayMax Human Fibrinogen ELISA Kit

AssayMax Human Fibrinogen ELISA Kit AssayMax Human Fibrinogen ELISA Kit Assaypro LLC 3400 Harry S Truman Blvd St. Charles, MO 63301 T (636) 447-9175 F (636) 395-7419 www.assaypro.com For any questions regarding troubleshooting or performing

More information

K. Doubleday S. Kumnick. Clot Signature Curves and the ACLAdvance TM

K. Doubleday S. Kumnick. Clot Signature Curves and the ACLAdvance TM COAGULATION 12 K. Doubleday S. Kumnick Clot Signature Curves and the ACLAdvance TM K. Doubleday S. Kumnick Clot Signature Curves and the ACL Advance TM Index 3 What is a Clot Signature Curve Pag. 5 How

More information

HEMOCHRON. Whole Blood Coagulation Systems

HEMOCHRON. Whole Blood Coagulation Systems HEMOCHRON Whole Blood Coagulation Systems Activated Partial Thromboplastin Time (APTT) Cuvette Correlation Protocol for HEMOCHRON Microcoagulation Instruments MSIG: 49 10/06 Dear Medical Professional:

More information

These handouts are only meant as a guide while you follow the presentation on the screen. Sometimes the speaker will change some of the slides.

These handouts are only meant as a guide while you follow the presentation on the screen. Sometimes the speaker will change some of the slides. These handouts are only meant as a guide while you follow the presentation on the screen. Sometimes the speaker will change some of the slides. If you would like the 1 slide per page handouts, please ask

More information

OUR IN VITRO DIAGNOSTICS IDENTITY CLINICAL CHEMISTRY IMMUNOASSAY AND AUTOMATION AUTOIMMUNITY

OUR IN VITRO DIAGNOSTICS IDENTITY CLINICAL CHEMISTRY IMMUNOASSAY AND AUTOMATION AUTOIMMUNITY OUR IN VITRO DIAGNOSTICS IDENTITY SEROLOGY CLINICAL CHEMISTRY COAGULATION IMMUNOASSAY AND AUTOMATION AUTOIMMUNITY SCLAVO DIAGNOSTICS INTERNATIONAL CONSTANT IMPROVEMENT AND DEVELOPMENT OF OUR PRODUCTS SCLAVO

More information

Influence of Residual Platelet Count on Routine Coagulation, Factor VIII, and Factor IX Testing in Postfreeze-Thaw Samples

Influence of Residual Platelet Count on Routine Coagulation, Factor VIII, and Factor IX Testing in Postfreeze-Thaw Samples 834 Influence of Residual Platelet Count on Routine Coagulation, Factor VIII, and Factor IX Testing in Postfreeze-Thaw Samples Giuseppe Lippi, MD 1 Rossana Rossi, PhD 1 Luigi Ippolito, MD 1 Valentina Zobbi,

More information

cobas 8100 automated workflow series 3-D intelligence in lab automation

cobas 8100 automated workflow series 3-D intelligence in lab automation 3-D intelligence in lab automation Personalized Lab Automation Maximizing Testing Efficiency and Medical Value Hospital network At Roche, laboratory automated solutions deliver the quality and reliability

More information

Apheresis Anticoagulant Removal. Oluwatoyosi Onwuemene, MD MS May 6th, 2017

Apheresis Anticoagulant Removal. Oluwatoyosi Onwuemene, MD MS May 6th, 2017 Apheresis Anticoagulant Removal Oluwatoyosi Onwuemene, MD MS May 6th, 2017 Talk Outline Case presentation Factors associated with drug removal TPE s effects on hematologic parameters Anticoagulant properties

More information

High Five for venous blood collection for immunoassays

High Five for venous blood collection for immunoassays High Five for venous blood collection for immunoassays Preanalytical errors are said to be the reason for up to 62 % of all errors in laboratory medicine [1]. Here are some tips on how to avoid the most

More information

Rat Fibrinogen ELISA Kit

Rat Fibrinogen ELISA Kit AssayMax TM Rat Fibrinogen ELISA Kit Assaypro LLC 3400 Harry S Truman Blvd St. Charles, MO 63301 T (636) 447-9175 F (636) 395-7419 www.assaypro.com For any questions regarding troubleshooting or performing

More information

Laboratory Investigation of Challenging Cases. Laura A. Worfolk, Ph.D Scientific Director, Coagulation

Laboratory Investigation of Challenging Cases. Laura A. Worfolk, Ph.D Scientific Director, Coagulation Laboratory Investigation of Challenging Cases Laura A. Worfolk, Ph.D Scientific Director, Coagulation Coagulation Cascade XII XIIa XI HMWK/Prekallikrein XIa VII Injury IX X IXa VIII Xa X TF TF/VIIa Prothrombin

More information

R.Li, C.Swaelens, F.Vandermijnsbrugge, B.Cantinieaux BSTH Laboratory of haematology, Porte de Hal,

R.Li, C.Swaelens, F.Vandermijnsbrugge, B.Cantinieaux BSTH Laboratory of haematology, Porte de Hal, Institut J. Bordet Normal with Actin-FS avoids intrinsic pathway factors assays in the presence of an isolated prolongation of (Platelin-LS) without hemorrhagic history R.Li, C.Swaelens, F.Vandermijnsbrugge,

More information

Laboratory investigation in the Bleeding Patient. Dr Craig Taylor Consultant Haematologist May 2016

Laboratory investigation in the Bleeding Patient. Dr Craig Taylor Consultant Haematologist May 2016 Laboratory investigation in the Bleeding Patient Dr Craig Taylor Consultant Haematologist May 2016 Introduction Bleeding is common May consume significant resources Crossmatched blood Lab results may be

More information

SAMPLE. Determination of Coagulation Factor Activities Using the One-Stage Clotting Assay

SAMPLE. Determination of Coagulation Factor Activities Using the One-Stage Clotting Assay 2nd Edition H48 Determination of Coagulation Factor Activities Using the One-Stage Clotting Assay This guideline provides recommendations regarding the proper collection and handling of specimens, reagents,

More information

SEED Coagulation. Sysmex Educational Enhancement and Development April 2014

SEED Coagulation. Sysmex Educational Enhancement and Development April 2014 SEED Coagulation Sysmex Educational Enhancement and Development April 2014 The Thrombin Time Test and Reptilase Test what is their role in coagulation testing? Baseline screening tests of coagulation The

More information

Biological Variation of Hemostasis Variables in Thrombosis and Bleeding: Consequences for Performance Specifications

Biological Variation of Hemostasis Variables in Thrombosis and Bleeding: Consequences for Performance Specifications Papers in Press. Published September 27, 2016 as doi:10.1373/clinchem.2016.261248 The latest version is at http://hwmaint.clinchem.aaccjnls.org/cgi/doi/10.1373/clinchem.2016.261248 Clinical Chemistry 62:12

More information

Haemostasis. The function of haemostasis is: to prevent blood loss from injured vessels. to stop bleeding. to prevent thrombosis

Haemostasis. The function of haemostasis is: to prevent blood loss from injured vessels. to stop bleeding. to prevent thrombosis Haemostasis Haemostasis The function of haemostasis is: to prevent blood loss from injured vessels to stop bleeding to prevent thrombosis Haemostasis blood endothelium basement membrane subendothelium

More information

Evaluation of the Bleeding Patient

Evaluation of the Bleeding Patient Evaluation of the Bleeding Patient Screening Tests Rong He, MD Special Coagulation Laboratory, Division of Hematopathology 2015 MFMER slide-1 DISCLOSURE Relevant Financial Relationship(s) None 2015 MFMER

More information

Human Protein Z ELISA Kit

Human Protein Z ELISA Kit AssayMax Human Protein Z ELISA Kit Assaypro LLC 3400 Harry S Truman Blvd St. Charles, MO 63301 T (636) 447-9175 F (636) 395-7419 www.assaypro.com For any questions regarding troubleshooting or performing

More information

Please note that the uses described in the following page(s) have not been approved or cleared by FDA, with respect to the described assay or test.

Please note that the uses described in the following page(s) have not been approved or cleared by FDA, with respect to the described assay or test. Please note that the uses described in the following page(s) have not been approved or cleared by FDA, with respect to the described assay or test. In the US, the product is intended For Research Use Only.

More information

Prothrombin (Factor II) IgG ELISA

Prothrombin (Factor II) IgG ELISA Prothrombin (Factor II) IgG ELISA Quantitative assay for anti-prothrombin IgG antibodies For Research Use Only. Not For Use In Diagnostic Procedures. Updates from previous version: 09/03 are non-critical

More information

Human Factor IX (FIX)

Human Factor IX (FIX) Human Factor IX (FIX) ELISA Kit Assaypro LLC 3400 Harry S Truman Blvd St. Charles, MO USA 63301 T: +1 (636) 447-9175 F: +1 (636) 395-7419 www.assaypro.com Emergo Europe Molenstraat 15 2513 BH The Hague

More information

Internal Quality Control Practices in Coagulation Laboratories: recommendations based on a patterns-of-practice survey

Internal Quality Control Practices in Coagulation Laboratories: recommendations based on a patterns-of-practice survey International Journal of Laboratory Hematology ORIGINAL ARTICLE The Official journal of the International Society for Laboratory Hematology INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY Internal Quality

More information

Haemostasis Laboratory, University of Glasgow, Glasgow Royal Infirmary. Prepared by Ann Rumley, Estelle Poorhang. 03/05/05

Haemostasis Laboratory, University of Glasgow, Glasgow Royal Infirmary. Prepared by Ann Rumley, Estelle Poorhang. 03/05/05 Haemostasis Laboratory, University of Glasgow, Glasgow Royal Infirmary. Prepared by Ann Rumley, Estelle Poorhang. 03/05/05 Standard Operating Procedure for Determination of clottable (Clauss) fibrinogen

More information

2 Thomas G. DeLoughery

2 Thomas G. DeLoughery Tests of Hemostasis and Thrombosis 2 Thomas G. DeLoughery A routine laboratory test once well-established is often slavishly adhered to, with little further thought about how it originated, why it is done

More information

Customer Service. For further product information, technical advice, prices or to place an order contact. Phone:

Customer Service. For further product information, technical advice, prices or to place an order contact. Phone: Customer Service For further product information, technical advice, prices or to place an order contact Phone: + 43 1 86373-0 Fax: + 43 1 86373-44 Sales: sales@technoclone.com Product Support: products@technoclone.com

More information

AssayMax Human Factor V ELISA Kit

AssayMax Human Factor V ELISA Kit AssayMax Human Factor V ELISA Kit Assaypro LLC 3400 Harry S Truman Blvd St. Charles, MO 63301 T (636) 447-9175 F (636) 395-7419 www.assaypro.com For any questions regarding troubleshooting or performing

More information

Coagulation in perspective: Blood management. Objectives

Coagulation in perspective: Blood management. Objectives Coagulation in perspective: Blood management Julie Wegner, PhD jawrbl@gmail.com Objectives To gain a basic understanding of the following: 1. Coagulation components and processes Why patients bleed. 2.

More information

Human Myostatin, ELISA Kit (MSTN)

Human Myostatin, ELISA Kit (MSTN) Human Myostatin, ELISA Kit (MSTN) 96 Tests Catalog Number: MBS733837 Store all reagents at 2-8 C Valid Period: six months For samples: Cell culture fluid & body fluid & tissue homogenate Serum or blood

More information

AssayMax Human Factor XIII ELISA Kit

AssayMax Human Factor XIII ELISA Kit AssayMax Human Factor XIII ELISA Kit Assaypro LLC 3400 Harry S Truman Blvd St. Charles, MO 63301 T (636) 447-9175 F (636) 395-7419 www.assaypro.com For any questions regarding troubleshooting or performing

More information

Management & Administration

Management & Administration Laboratory Evaluation of the STA Satellite Benchtop Coagulation Instrument Ha T Su, MT(ASCP) CM, 1 Katherine L Whelchel, MT(ASCP)SH, 2 Mary Jo Sonnek, MT(ASCP), 1 and Gwyn A. Cutsforth, PhD 2 * ABSTRACT

More information

Activated Partial Thromboplastin Time and Anti-Xa Measurements in Heparin Monitoring. Biochemical Basis for Discordance

Activated Partial Thromboplastin Time and Anti-Xa Measurements in Heparin Monitoring. Biochemical Basis for Discordance Coagulation and Transfusion Medicine / vs Level Discrepancies ctivated Partial Thromboplastin Time and Measurements in Heparin Monitoring iochemical asis for Discordance Clifford M. Takemoto, MD, 1 Michael.

More information

Disclosures. Thromboelastography. TEG Methodology. TEG Output. Thromboelastography (TEG): Basics & Clinical Applications

Disclosures. Thromboelastography. TEG Methodology. TEG Output. Thromboelastography (TEG): Basics & Clinical Applications Thromboelastography (TEG): Basics & Clinical Applications Paula J. Santrach MD Associate Professor, Laboratory Medicine Mayo Clinic Rochester, MN Disclosures Relevant financial relationships NONE Off label

More information

ECAT FOUNDATION. External quality Control of diagnostic Assays and Tests with a focus on Thrombosis and Haemostasis

ECAT FOUNDATION. External quality Control of diagnostic Assays and Tests with a focus on Thrombosis and Haemostasis ECAT FOUNDATION External quality Control of diagnostic Assays and Tests with a focus on Thrombosis and Haemostasis PROGRAMME MANUAL 2017 ECAT FOUNDATION Postal address Visiting address ECAT Foundation

More information

SAMPLE H21-A5. January 2008

SAMPLE H21-A5. January 2008 January 2008 Collection, Transport, and Processing of Blood Specimens for Testing Plasma-Based Coagulation Assays and Molecular Hemostasis Assays; Approved Guideline Fifth Edition This document provides

More information

Selectra ProM. Delivering trouble free results laboratories can trust. CLINICAL SYSTEMS About ELITechGroup Clinical Systems...

Selectra ProM. Delivering trouble free results laboratories can trust. CLINICAL SYSTEMS About ELITechGroup Clinical Systems... About ELITechGroup Clinical Systems... SPECIFICATIONS THROUGHPUT Typically 180 tests / hour; Up to 266 ISE tests / hour. Measuring temperature 37 C, REAGENT Refrigerated reagent rotor controlled with Peltier

More information

Serum vs Plasma. Which specimen should you use? American Society for Clinical Laboratory Science Michigan Annual Meeting

Serum vs Plasma. Which specimen should you use? American Society for Clinical Laboratory Science Michigan Annual Meeting Serum vs Plasma Which specimen should you use? American Society for Clinical Laboratory Science Michigan Annual Meeting Sol Green PhD FACB March 31 2016 Introduction This presentation is intended to provide

More information

Laboratory Aspects of recombinant porcine FVIII and extended half life concentrates

Laboratory Aspects of recombinant porcine FVIII and extended half life concentrates Laboratory Aspects of recombinant porcine FVIII and extended half life concentrates Rajiv K. Pruthi, M.B.B.S Co-Director, Special Coagulation Laboratory & Director, Mayo Comprehensive Hemophilia Center

More information

Use of Chromogenic Assay of Factor X to Accept or Reject INR Results in Warfarin Treated Patients

Use of Chromogenic Assay of Factor X to Accept or Reject INR Results in Warfarin Treated Patients CM&R Rapid Release. Published online ahead of print July 22, 2009 as Use of Chromogenic Assay of Factor X to Accept or Reject INR Results in Warfarin Treated Patients Michael J. Sanfelippo, MS, MT ASCP;

More information

Common Inherited Bleeding Disorders

Common Inherited Bleeding Disorders CAA 2015 Annual Conference Common Inherited Bleeding Disorders Bob Miller, A October 8, 2015 VWF has two jobs Loosely bound to protect FVIII and tether to site of injury All other coagulation factors also

More information

Human alpha-1-antitrypsin ELISA Kit

Human alpha-1-antitrypsin ELISA Kit AssayMax Human alpha-1-antitrypsin ELISA Kit Assaypro LLC 3400 Harry S Truman Blvd St. Charles, MO 63301 T (636) 447-9175 F (636) 395-7419 www.assaypro.com For any questions regarding troubleshooting or

More information

AssayMax Human Antithrombin III ELISA Kit

AssayMax Human Antithrombin III ELISA Kit AssayMax Human Antithrombin III ELISA Kit Catalog # EA3302-1 Introduction The serine-protease-inhibitor antithrombin III (AT III), the most important natural inhibitor of thrombin activity, has been shown

More information

Special Specimen Collection Procedures for Coagulation Testing

Special Specimen Collection Procedures for Coagulation Testing Special Specimen Collection Procedures for Coagulation Testing The accuracy of hemostasis testing depends upon the quality of the specimen submitted. Hemostasis specimens must be properly collected, labeled,

More information

PCR SYSTEMS. a new era in high-productivity qpcr. Applied Biosystems ViiA 7 Real-Time PCR System

PCR SYSTEMS. a new era in high-productivity qpcr. Applied Biosystems ViiA 7 Real-Time PCR System PCR SYSTEMS a new era in high-productivity qpcr Applied Biosystems ViiA 7 Real-Time PCR System a new era in high-productivity qpcr The ViiA 7 Real-Time PCR System delivers the proven reliability, sensitivity,

More information

PERFUSION TECHNOLOFISTS OF GREATER CHICAGO, INC. POLICY AND PROCEDURE MEDTRONIC HEMOTEC ACTIVATED CLOTTING TIME (ACT) OPERATING PROCEDURE

PERFUSION TECHNOLOFISTS OF GREATER CHICAGO, INC. POLICY AND PROCEDURE MEDTRONIC HEMOTEC ACTIVATED CLOTTING TIME (ACT) OPERATING PROCEDURE DATE OF REVISION Page 1 of 13 (ACT) OPERATING PROCEDURE PRINCIPLE: The ACT test is a definitive test used to monitor the anticoagulant effect of heparin. It measures the clotting time of fresh whole blood

More information

Blood Product Utilization

Blood Product Utilization Who gets what & when Why not to give blood? Volume Expander For specific number (except as related to procedures) To patients with religious objections to blood transfusions Blood given only when necessary

More information

Sign up to receive ATOTW weekly -

Sign up to receive ATOTW weekly - BLOOD PHYSIOLOGY PART 2 ANAESTHESIA TUTORIAL OF THE WEEK 231 11 TH JULY 2011 Dr Karen Hayes Royal Devon & Exeter Correspondence to: kmhayes@hotmail.co.uk QUESTIONS Before continuing, try to answer the

More information

Basic coagulation applications and case studies

Basic coagulation applications and case studies Basic coagulation applications and case studies Jing Jin Clinical laboratory Scientist (MLS, ASCP) - Coagulation/Hematology Stanford University Hospital and Clinics 1 Agenda Overview about 3 major phases

More information

The Simple Solution for CBC Testing

The Simple Solution for CBC Testing QBC STAR Centrifugal Hematology Analyzer The Simple Solution for CBC Testing Diagnostics Innovative Solutions for a Healthier World UNRIVALED SIMPLICITY The QBC STAR Centrifugal Hematology System is the

More information

IQCP for the Akers Bio PIFA Heparin Platelet Factor 4 Rapid Assay

IQCP for the Akers Bio PIFA Heparin Platelet Factor 4 Rapid Assay On December 31, 2015 the ability to use Equivalent Quality Control (EQC) policies will expire. Laboratories will be required to either follow the quality control regulations as outlined in CLIA 88 or develop

More information

BN II The power of choice

BN II The power of choice BN II The power of choice BN II The intelligent system for The BN II, with more than 1500 instruments sold so far, is one of the latest additions to the successful range of BN systems. This third generation

More information

cobas p 512 pre-analytical system Adapting to today s needs. Flexible for tomorrow s demand.

cobas p 512 pre-analytical system Adapting to today s needs. Flexible for tomorrow s demand. cobas p 512 pre-analytical system Adapting to today s needs. Flexible for tomorrow s demand. Personalized Lab Automation Maximizing testing efficiency and medical value Hospital network At Roche, laboratory

More information

cobas p 512 pre-analytical system Adapting to today s needs. Flexible for tomorrow s demand.

cobas p 512 pre-analytical system Adapting to today s needs. Flexible for tomorrow s demand. cobas p 512 pre-analytical system Adapting to today s needs. Flexible for tomorrow s demand. Personalized Lab Automation Maximizing Testing Efficiency and Medical Value At Roche, laboratory automated solutions

More information

Siemens showcases prothrombin time testing system developed with Universal Biosensors at IFCC EuromedLab 2013 in Milan, Italy

Siemens showcases prothrombin time testing system developed with Universal Biosensors at IFCC EuromedLab 2013 in Milan, Italy Universal Biosensors Inc ARBN 121 559 993 1 Corporate Avenue Rowville VIC 3178 Australia Telephone +61 3 9213 9000 Facsimile +61 3 9213 9099 Email info@universalbiosensors.com www.universalbiosensors.com

More information

APOB (Human) ELISA Kit

APOB (Human) ELISA Kit APOB (Human) ELISA Kit Catalog Number KA1028 96 assays Version: 17 Intended for research use only www.abnova.com Table of Contents Introduction... 3 Background... 3 Principle of the Assay... 3 General

More information

Interferences in coagulation tests evaluation of the 570-nm method on the Dade Behring BCS analyser

Interferences in coagulation tests evaluation of the 570-nm method on the Dade Behring BCS analyser Clin Chem Lab Med 2005;43(2):244 252 2005 by Walter de Gruyter Berlin New York. DOI 10.1515/CCLM.2005.041 2005/32 Interferences in coagulation tests evaluation of the 570-nm method on the Dade Behring

More information

AssayMax Human Transferrin ELISA Kit

AssayMax Human Transferrin ELISA Kit AssayMax Human Transferrin ELISA Kit Assaypro LLC 3400 Harry S Truman Blvd St. Charles, MO 63301 T (636) 447-9175 F (636) 395-7419 www.assaypro.com For any questions regarding troubleshooting or performing

More information

Errors in Clinical Biochemistry Laboratory

Errors in Clinical Biochemistry Laboratory British Journal of Medicine & Medical Research 14(8): 1-6, 2016, Article no.bjmmr.25012 ISSN: 2231-0614, NLM ID: 101570965 SCIENCEDOMAIN international www.sciencedomain.org Errors in Clinical Biochemistry

More information

Suitability of analytical methods for detection of thrombogenic factor XIa in Privigen

Suitability of analytical methods for detection of thrombogenic factor XIa in Privigen Suitability of analytical methods for detection of thrombogenic factor XIa in Privigen Absence of thrombogenic factors in Privigen M. Moses, K. Ruhwedel, H.-A. Stöhr, L. Duse, A. Feussner, W. Wormsbächer,

More information

Effect of Direct Thrombin Inhibitors, Bivalirudin, Lepirudin, and Argatroban, on Prothrombin Time and INR Values

Effect of Direct Thrombin Inhibitors, Bivalirudin, Lepirudin, and Argatroban, on Prothrombin Time and INR Values Coagulation and Transfusion Medicine / DIRECT THROMBIN INHIBITOR EFFECT ON INR Effect of Direct Thrombin Inhibitors, Bivalirudin, Lepirudin, and Argatroban, on Prothrombin Time and INR Values Robert C.

More information

Schedule of Accreditation issued by United Kingdom Accreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK

Schedule of Accreditation issued by United Kingdom Accreditation Service 2 Pine Trees, Chertsey Lane, Staines-upon-Thames, TW18 3HR, UK Haemostasis & Thrombosis Department St. Thomas Hospital Westminster Bridge Road London SE1 7EH United Kingdom Contact: Beverly Earl Tel: +44 (0) 20 7188 0084 Fax: +44 (0) 20 7188 2726 E-Mail: beverley.earl@viapath.co.uk

More information

AssayMax Human Albumin ELISA Kit

AssayMax Human Albumin ELISA Kit AssayMax Human Albumin ELISA Kit Assaypro LLC 3400 Harry S Truman Blvd St. Charles, MO 63301 T (636) 447-9175 F (636) 395-7419 www.assaypro.com For any questions regarding troubleshooting or performing

More information

VALIDATION GUIDE FOR CHROMOGENIC ASSAY FOR ACTIZYME Anti-FIIa

VALIDATION GUIDE FOR CHROMOGENIC ASSAY FOR ACTIZYME Anti-FIIa VALIDATION GUIDE FOR CHROMOGENIC ASSAY FOR ACTIZYME Anti-FIIa Chromogenic assay for testing heparins (UFH, LMWH and Enoxaparin) in purified systems by measurement of FIIa Inhibition, in compliance with

More information

Nephelometry and turbidimetry are liquid based immunoassays based on the measurement of scattered or absorbed light.

Nephelometry and turbidimetry are liquid based immunoassays based on the measurement of scattered or absorbed light. 1 Nephelometry and turbidimetry are liquid based immunoassays based on the measurement of scattered or absorbed light. Light scattering is the physical phenomenon resulting from the interaction of light

More information

Coagulation: The Ins and Outs. Sheila K. Coffman BSMT (ASCP)

Coagulation: The Ins and Outs. Sheila K. Coffman BSMT (ASCP) Coagulation: The Ins and Outs Sheila K. Coffman BSMT (ASCP) Coagulation Testing: What is it? Monitoring hemostasis Bleeding Clotting Coagulation Testing Monitoring therapy Heparin Monitor with ACT / aptt

More information

Human Complement C3 ELISA Kit

Human Complement C3 ELISA Kit AssayMax Human Complement C3 ELISA Kit Assaypro LLC 3400 Harry S Truman Blvd St. Charles, MO 63301 T (636) 447-9175 F (636) 395-7419 www.assaypro.com For any questions regarding troubleshooting or performing

More information

Expert workflow management cobas p 612 pre-analytical system Professional management of laboratory processes

Expert workflow management cobas p 612 pre-analytical system Professional management of laboratory processes Expert workflow management cobas p 612 pre-analytical system Professional management of laboratory processes COBAS, COBAS INTEGRA, COBAS E, COBAS P, MODULAR PRE-ANALYTICS EVO, ELECSYS and LIFE NEEDS ANSWERS

More information

ROTEM Basic Interpretation Guide

ROTEM Basic Interpretation Guide ROTEM Basic Interpretation Guide Parameter: Clotting Time CT - Clotting Time (seconds) The time from the start of the test until first significant levels of a clot are detected. This measurement is initiated

More information

The Combined Use of Bypassing Agents with Antithrombin Reduction in Plasma of Hemophilia A and B Patients with Inhibitors

The Combined Use of Bypassing Agents with Antithrombin Reduction in Plasma of Hemophilia A and B Patients with Inhibitors Venkat Living Venkat with Hemophilia Living with Hemophilia The Combined Use of Bypassing Agents with Antithrombin Reduction in Plasma of Hemophilia A and B Patients with Inhibitors Tami Livnat 1, Alfica

More information

Human Bordetella Pertussis IgG ELISA kit

Human Bordetella Pertussis IgG ELISA kit Human Bordetella Pertussis IgG ELISA kit Catalog number: NR-R10157 (96 wells) The kit is designed to qualitatively detect Bordetella Pertussis IgG in Human serum or plasma. FOR RESEARCH USE ONLY. NOT FOR

More information

Expert workflow management cobas p 612 pre-analytical system. Professional management of laboratory processes

Expert workflow management cobas p 612 pre-analytical system. Professional management of laboratory processes Expert workflow management cobas p 612 pre-analytical system Professional management of laboratory processes Expert workflow management Concept Professional management of processes in diagnostic laboratories

More information

cobas p 612 pre-analytical system Adapting to today s needs. Flexible for tomorrow s demand.

cobas p 612 pre-analytical system Adapting to today s needs. Flexible for tomorrow s demand. cobas p 612 pre-analytical system Adapting to today s needs. Flexible for tomorrow s demand. Personalized Lab Automation Maximizing Testing Efficiency and Medical Value At Roche, laboratory automated solutions

More information

Human Angiotensin 2 (Ang2) ELISA

Human Angiotensin 2 (Ang2) ELISA Human Angiotensin 2 (Ang2) ELISA For the quantitative determination of human Ang2 in serum, plasma, cell culture fluid and other biological fluids Cat. No. KT-52748 For Research Use Only. Not for use in

More information

ab Factor VIIIa Activity Assay Kit (Fluorometric)

ab Factor VIIIa Activity Assay Kit (Fluorometric) ab204696 Factor VIIIa Activity Assay Kit (Fluorometric) Instructions for Use For rapid, sensitive and accurate detection of Factor VIII activity. This product is for research use only and is not intended

More information

Human Plasmin Activity Assay ELISA Kit

Human Plasmin Activity Assay ELISA Kit Human Plasmin Activity Assay ELISA Kit Catalog No. CSI12527A 1 x 96 tests CSI12527B 5 x 96 tests Intended Use: Background: Assay Principle: Reagents Provided: This human plasmin activity assay is for the

More information