Third Annual Biotech Industry Night March 31, 2008

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1 Third Annual Biotech Industry Night March 31, 2008 Event Program

2 Welcome to the 3 rd Annual Caltech Biotech Industry Night Industry Night was conceptualized in response to limited recruiting at Caltech from leading biotechnology and pharmaceutical companies. Each year, we invite representatives from companies around the nation to participate in this event. We aim to introduce Caltech faculty, postdocs, and students to the leading companies in industry. Furthermore, Industry Night allows industry representatives to sample the wealth of talent that exists in the Caltech community. 2

3 3 rd Annual Biotech Industry Night Monday, March 31, 2008 Caltech Alumni House 5:00pm Welcome, Keynote by Prof. Jim Heath 5:00pm 7:00pm Meet-and-greet with Company Representatives 3

4 Special Thanks to our Event Sponsors: Caltech Alumni Association Caltech Career Development Center Caltech Office of Technology Transfer Yahoo! Momentum Biosciences, LLC Event Planning Committee John Nagarah Graduate Student, Chemistry Chistie Canaria Graduate Student, Chemistry Virginie Goubert Staff Heidi Privett Graduate Student, Chemistry Sean Gordon Graduate Student, Biology Diana Dou Undergraduate Joe Zadeh Graduate Student, Bioengineering Angela Wood Asst Director, Career Development Center Cathreen Oracion Career Development Center Karen Carlson Associate Director, Alumni Assoc. Tami M. Penunuri Alumni Assoc. 4

5 About our club The Caltech Biotechnology Club is a student-run organization whose mission is to connect the Caltech community with the biotechnology field. Our members include Caltech undergraduate and graduate students, postdoctoral scholars, staff, faculty, and individuals from the biotechnology industry. The Biotech Club Executive Board John Nagarah Christie Canaria Heidi Privett Joseph Zadeh Simon Kung Virginie Goubert Sean Gordon Diana Dou Co-president Co-president Treasurer Director of Communications Webmaster We wish to thank your corporate annual sponsors for their generous donations: For more information about how to become a sponsor, please visit us on the web at Club contact information: biotech@caltech.edu Website: Mail: MC E. California Blvd. Pasadena, CA

6 Participating Companies 6

7 Genentech, Inc. engages in the discovery, development, manufacture, and commercialization of biotherapeutics for various medical needs. The company provides various products for the treatment of cancer, allergic asthma, plaque psoriasis, hormone deficiency, heart attack, blood clots in the brain and lungs, and cystic fibrosis. Its product portfolio includes Rituxan, an anti-cd20 antibody; Avastin, an anti-vegf humanized antibody; Herceptin, a humanized anti-her2 antibody; Tarceva, a small molecule inhibitor of the tyrosine kinase activity; Xolair, a humanized anti- IgE antibody; Nutropin and Nutropin AQ, which are growth hormone products; Activase, a tissue plasminogen activator; and others. Genentech was founded in 1975 and is headquartered in South San Francisco, California. Source: Yahoo! Finance Representative: Ying Gong, Ph.D. 7

8 Amgen, Inc. engages in the discovery, development, manufacture, and marketing of human therapeutics based on advances in cellular and molecular biology. It offers human therapeutic products in the areas of inflammation, nephrology, and supportive cancer care. The company s principal products include Aranesp and EPOGEN, which stimulate the production of red blood cells to treat anemia; Neulasta and NEUPOGEN that stimulate the production of neutrophils, a white blood cell that enables the body fight infections; and Enbrel, which blocks the biologic activity of tumor necrosis factor (TNF) by inhibiting TNF, a substance induced in response to inflammatory and immunological responses, such as rheumatoid arthritis and psoriasis. The company was incorporated in 1980 and is based in Thousand Oaks, California. Source: Yahoo! Finance Representative: Helen McBride, Ph.D. 8

9 Established in 2006, Momentum Biosciences is a private investment and advisory group consisting of University of California, Los Angeles (UCLA) and California Institute of Technology (Caltech) Faculty who are committed to accelerating the transfer of new healthcare technologies from the laboratory to the clinical and commercial environment. With a track record of both academic and commercial success, Momentum is well equipped to meet the technological and business challenges of new healthcare technology ventures. Our primary investment focus is on start-up projects at UCLA and Caltech where we work with bright researchers and faculty to assist them with their commercialization objectives, with particularfocus in biotechnology, nanotech and medical devices. We consider ourselves to be a partner of the institutional technology transfer organization and work cooperatively with University administration. Momentum provides advice and access to legal, licensing, administrative and business development resources as well as capital either directly or in partnership with other funding sources. Representative: 9

10 Among the most innovative new drugs on the market, antibody and protein biotherapeutics are changing the way physicians treat cancer, inflammation, and autoimmune disease. At Xencor, we make better biotherapeutics candidates by engineering antibodies and proteins to be potent treatments of life-threatening and debilitating diseases. Our unique Protein Design Automation suite of technologies allows us to systematically shape the clinical performance of protein-based drug leads to produce new drug candidates for development and commercialization by ourselves and by major life science and pharmaceutical partners. Representative: 10

11 The Alfred Mann Foundation is a medical research foundation dedicated to bringing advanced medical technologies to the public to provide significant improvements to the health, security and quality of life for people suffering from debilitating medical conditions Representative: 11

12 Huntington Medical Research Institutes HMRI is an independent, nonprofit, public-benefit organization dedicated to improving health and prolonging life by enhancing knowledge of life processes and disease, and by developing technology to diagnose and treat diseases. New programs include molecular oncology, molecular neurology and brain mapping (magnetoencephalography, or MEG), liver studies and asthma and allergy. HMRI provides advanced training in magnetic resonance spectroscopy, co-sponsors postdoctoral fellowships with the California Institute of Technology, and conducts mentor programs for college and graduate level science students. Each year a summer student program offers unique opportunities to explore careers in medical research. Representative: 12

13 At Bend Research, our core business is the development of new technologies for the pharmaceutical industry. We began operations in Central Oregon in 1975 and, since that time, have focused on applying fundamental scientific and engineering principles to understand our clients needs, to help our clients define their problems, and to provide enabling, novel, and proprietary new technologies to address those needs. In our Tumalo laboratories, we conceive, explore the feasibility of, and characterize new approaches to meet needs for pharmaceutical technologies. In our new Corporate Place pilot facility, we develop processes and scale up these new technologies, as well as design and construct novel equipment. And in our cgmp facility Bend Research Pharmaceutical Process Development (BRPPD) we reduce these technologies to practice through the manufacture of clinical supplies. Finally, Bend Research scientists and engineers are involved in the scale-up and transfer of pharmaceutical processes into commercial manufacturing plants across the globe. Representative: 13

14 Codexis is a leading developer of biocatalytic chemical processes that can dramatically reduce manufacturing costs across a broad range of industries. Our proprietary technology enables novel solutions for cost-effective, efficient and environmentally sound production of pharmaceuticals, transportation fuels, and industrial chemicals. Our focus is on improving R&D productivity for our partners while significantly reducing their capital expenditures and cost-of-goods using green chemistry methods. Codexis maintains headquarters in Redwood City, CA and also serves its worldwide partners with facilities in Pasadena, CA., Germany, Hungary, Singapore and India. Representatives: 14

15 NOTES 15

16 Biotech Industry Night is hosted by the Caltech Biotechnology Club in coordination with the Caltech Career Development Center and the Caltech Alumni Association. We wish to thank the Caltech Office of Technology Transfer, Yahoo!, and Momentum Biosciences, LLC. for their financial contributions. We also wish to thank Amgen and Genentech for their annual sponsorship. For more information please visit us on the web at: 16

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