SAFETY DATA SHEET. SECTION 1: Identification of the substance/mixture and of the company/undertaking

Transcription

1 SAFETY DATA SHEET SECTION 1: Identification of the substance/mixture and of the company/undertaking Identification of the substance or mixture Product code Product name NP0005 NuPAGE Antioxidant Company/undertaking identification Life Technologies Corporation 5781 Van Allen Way PO Box 6482 Carlsbad, CA Life Technologies Korea 11&12 FL, Suseo Office Building 281 Gwangpyeong-ro, Gangnam-gu Seoul, , Korea T Guangzhou Office Room South Tower Guangzhou World Trade Center Complex HuanShi Dong Rd Yuexiu District Guangzhou , China Tel: Hotline: Fax: Life Technologies Co. Ltd 8F., No. 123, Sec. 2, Zhongxiao E. Rd. Zhongzheng District, Taipei City Taiwan Tel: Fax: Life Technologies New Zealand Limited Botha Road Penrose Auckland 1061 NEW ZEALAND Life Technologies Australia Pty Limited 5 Caribbean Drive Scoresby VIC 3179 AUSTRALIA Silver Tower-Beijing Office Room 1711 Beijing Silver Tower #2 DongSanHuan North Rd, Beijing P.R.China Tel: Fax: LIFE TECHNOLOGIES HOLDINGS PTE LTD BLK 33, MARSILING INDUSTRIAL ESTATE ROAD 3, #07-06, SINGAPORE (65) hour Emergency Response: (Australia) (New Zealand) (US) (US) (Outside of the U.S.) Country specific Emergency Number (if available): Revision date 15-Jun-2016 Page 1 / 8

2 CHEMTREC Israel (Tel Aviv) CHEMTREC Malaysia CHEMTREC Malaysia (Kuala Lumpur) CHEMTREC Philippines CHEMTREC Philippines (Manila) CHEMTREC Saudi Arabia CHEMTREC Singapore CHEMTREC Singapore CHEMTREC Australia (Sydney) CHEMTREC New Zealand (Auckland) CHEMTREC South Africa +(972) (Greeting Language: Hebrew) (Toll Free) (Greeting Language: Malay) +(60) (Greeting Language: Malay) (Toll Free) (Greeting Language: Tagalog) +(63) (Greeting Language: Tagalog) +(966) (Greeting Language: Arabic and English) (Toll Free) (Greeting Language: English and Mandarin) +(65) (Greeting Language: English and Mandarin) +(61) (Greeting Language: English) +(64) (Greeting Language: English) (Greeting Language: English) For research use only. Not intended for human or animal diagnostic or therapeutic uses. SECTION 2: Hazards identification Australian MSDS Statement Classified according to the criteria of Worksafe Australia. Hazardous Substance. Non-Dangerous Goods. GHS - Classification Signal word Danger Health hazards Serious eye damage/eye irritation Category 2 Reproductive toxicity Category 1B Physical hazards Not Hazardous hazard statements H319 - Causes serious eye irritation H360 - May damage fertility or the unborn child if swallowed Precautionary Statements Prevention P201 - Obtain special instructions before use P202 - Do not handle until all safety precautions have been read and understood P264 - Wash hands thoroughly after handling P280 - Wear protective gloves/protective clothing/eye protection/face protection Response P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P337 + P313 - If eye irritation persists: Get medical advice/attention Revision date 15-Jun-2016 Page 2 / 8

3 P308 + P313 - IF exposed or concerned: Get medical advice/attention Storage Not applicable Disposal P501 - Dispose of contents/ container to an approved waste disposal plant Principle Routes of Exposure/ Potential Health effects eyes Skin Inhalation INGESTION Specific effects Carcinogenic effects Mutagenic effects Reproductive toxicity Sensitisation Target Organ Effects Irritating to eyes. May cause skin irritation in susceptible persons. May cause irritation of respiratory tract. May be harmful if swallowed. No information available. Not applicable. May cause adverse reproductive effects - such as birth defect, miscarriages, or infertility. Not applicable. Not applicable SECTION 3: Composition/information on ingredients Component CAS-No. EINECS-No. Weight percent ( 7-13 ) We recommend handling all chemicals with caution. SECTION 4: First aid measures Skin contact Wash off immediately with plenty of water. In the case of skin irritation or allergic reactions see a doctor. Eye contact Rinse thoroughly with plenty of water for at least 15 minutes, lifting lower and upper eyelids. Consult a doctor. Call a doctor if irritation persists. INGESTION Rinse mouth. Consult a doctor if necessary. Do not induce vomiting without medical advice. Inhalation Remove to fresh air. Consult a doctor if necessary. Most important symptoms and effects, both acute and delayed H319 - Causes serious eye irritation, H360 - May damage fertility or the unborn child if swallowed Notes to Physician Treat symptomatically. SECTION 5: Firefighting measures Suitable extinguishing media Special protective equipment for firefighters Specific hazards arising from the chemical Foam. Dry powder. Dry chemical. Carbon dioxide (CO2). Water. Wear self-contained breathing apparatus and protective suit. Not known Revision date 15-Jun-2016 Page 3 / 8

4 SECTION 6: Accidental release measures Personal precautions Methods for cleaning up Avoid exposure to vapour. Avoid breathing vapours or mists. Ensure adequate ventilation. Avoid contact with skin, eyes or clothing. Use personal protection equipment. Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). Sweep up and shovel into suitable containers for disposal. Clean contaminated surface thoroughly. Environmental precautions No special environmental precautions required. See Section 12 for more information. SECTION 7: Handling and storage Handling Storage Always wear recommended Personal Protective Equipment. Avoid contact with skin, eyes or clothing. Use only in ventilated areas. Keep in properly labelled containers. Keep container tightly closed in a dry and well-ventilated place. Keep away from combustible material. SECTION 8: Exposure controls/personal protection Exposure Limits Australia STEL Australia Australia - Skin Absorbers Australia - OES - Peak 10 ppm Skin 30 mg/m 3 New Zealand - Workplace Exposure Limits skin notation New Zealand TWA New Zealand STEL New Zealand Ceiling Limits 10 ppm 30 mg/m 3 China OEL China - Skin Absorbers Hong Kong OEL STEL: 40 mg/m 3 Skin notation TWA: 10 ppm TWA: 20 mg/m 3 TWA: 30 mg/m 3 Korea OEL (CEILING) Korea OEL (TWA) Korea OEL (STEL) 10 ppm 30 mg/m 3 Taiwan OEL - TWA Taiwan OEL (Skin notations, Carcinogens) Taiwan OEL (STELs) 10 ppm Skin notation 15 ppm STEL; 45 mg/m 3 30 mg/m 3 STEL Taiwan OEL (Ceilings) Singapore OEL (PEL) Singapore OEL (STEL) 10 ppm 30 mg/m 3 Engineering measures Ensure adequate ventilation, especially in confined areas. Personal protective equipment Personal Protective Equipment requirements are dependent on the user institution's risk assessment and are specific to the risk assessment for each laboratory where this material may be used. Revision date 15-Jun-2016 Page 4 / 8

5 Respiratory protection In case of insufficient ventilation, wear suitable respiratory equipment. Hand Protection Eye protection Skin and body protection Hygiene measures Environmental exposure controls Impervious gloves. Safety glasses with side-shields. Lightweight protective clothing. Handle in accordance with good industrial hygiene and safety practice. No special environmental precautions required. SECTION 9: Physical and chemical properties General information Form liquid Appearance No information available Odour Mixture has not been tested Odour Threshold Mixture has not been tested Boiling point / boiling range C F Melting point / melting range C F flash point C F Autoignition temperature C F Evaporation rate Flammability (solid, gas) Oxidising properties Mixture has not been tested Water solubility soluble Upper explosion limit Lower explosion limit Partition coefficient: n-octanol/water Vapour Pressure vapour density Viscosity ph value Mixture has not been tested SECTION 10: Stability and reactivity Stability Materials to avoid Possibility of hazardous reactions Hazardous decomposition products polymerisation Conditions to avoid Stable under normal conditions. Strong oxidising agents. Acids. Bases. Sulphur trioxide. Iodine. Hazardous reaction has not been reported Hydrogen cyanide (hydrocyanic acid). Nitrogen oxides (NOx). Ammonia. Carbon monoxide. Hazardous polymerisation does not occur. under normal processing. Revision date 15-Jun-2016 Page 5 / 8

6 SECTION 11: Toxicological information Acute toxicity. LD50 (oral,rat/mouse) LD50 (dermal,rat/rabbit) LC50 (inhalation,rat/mouse) = 2000 mg/kg (Rat) = 2800 mg/kg (Rat) Principle Routes of Exposure/ Potential Health effects eyes Skin Inhalation INGESTION Carcinogenic effects Reproductive toxicity Target Organ Effects Irritating to eyes. May cause skin irritation in susceptible persons. May cause irritation of respiratory tract. May be harmful if swallowed. No information available. May cause adverse reproductive effects - such as birth defect, miscarriages, or infertility. Not applicable SECTION 12: Ecological information Ecotoxicity Mobility Biodegradation Bioaccumulation The environmental impact of this product has not been fully investigated. see log Pow. No information available. No information available. Freshwater Algae Data Desmodesmus subspicatus EC50>500 mg/l (96 h) Water Flea Data Daphnia magna EC mg/l (48 h) Daphnia magna EC50=8485 mg/l (48 h) Daphnia magna EC50=7500 mg/l (48 h) Freshwater Fish Species Data Microtox Data log Pow logpow SECTION 13: Disposal considerations Dispose of contents/containers in accordance with local regulations. SECTION 14: Transport information IATA Proper Shipping Name Hazard Class Subsidiary class Packing group UN-No Not classified as dangerous in the meaning of transport regulations. Revision date 15-Jun-2016 Page 6 / 8

7 SECTION 15: Regulatory information International Inventories US TSCA Canada (DSL) NDSL PICCS (Philippines) Listed Listed - Listed ENCS (Japan) IECSC - China Inventory of South Korea (KECL) AICS (Australia) Existing Chemical Substances Listed Listed Listed Listed NZIoC - New Zealand Inventory of EINECS (European Union) ELINCS (European List of Chemicals Notified Chemical Substances) Listed Listed - Korea Industrial Safety and Health Act (ISHA) 1 % Reproductive Tox. 1B 10 ppm TWA; 30 mg/m 3 TWA 10ppm TWA 30mg/m 3 TWA Skin notation Chemicals Control Act (CCA) 0.3 Wastes Control Act National Emergency Management Agency (NEMA) - Dangerous Substances Taiwan Toxic Chemical Substances Control Act - Classification and Control Levels Toxic Chemical Substances Control Act - Threshold Regulated Quantities Hazard Prevention Standard for Specified Chemical Substances Class 2 Cutoff: 30 wt% 50 kg TRQ Not Listed China China - Catalogue of Occupational Hazard Factors Dimethyl formamide poisoning China - Dangerous Goods List Present China - Catalog of Hypertoxic Chemicals China - List of Dangerous Chemicals for Priority Management SECTION 16: Other information Reason for revision SDS sections updated. For research use only. References ECHA:htp:/echa.europa.eu/ Revision date 15-Jun-2016 Page 7 / 8

8 TOXNET:htp:/toxnet.nlm.nih.gov/ echemportal:htp:/ LOLIdatabase "The above information was acquired by diligent search and/or investigation and the recommendations are based on prudent application of professional judgment. The information shall not be taken as being all inclusive and is to be used only as a guide. All materials and mixtures may present unknown hazards and should be used with caution. Since the Company cannot control the actual methods, volumes, or conditions of use, the Company shall not be held liable for any damages or losses resulting from the handling or from contact with the product as described herein. THE INFORMATION IN THIS SDS DOES NOT CONSTITUTE A WARRENTY, EXPRESSED OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PUPOSE" End of Safety Data Sheet Revision date 15-Jun-2016 Page 8 / 8