VWR CO 2 RESISTANT TUBES

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1 VWR CO 2 RESISTANT TUBES Protects Samples Shipped on Keeps ph Stable CO 2 Resistant Certified for Shipping

2 VWR CO 2 VWR CO 2 Only VWR s CO 2 Resistant Tubes are designed to protect samples that are shipped or stored on dry ice! Samples of proteins, other biological molecules, and cell cultures are commonly shipped and stored on dry ice, putting them at risk of acidification by up to 2.5 ph units. In standard centrifuge tubes, CO 2 vapor from dry ice enters the tube headspace and causes a significant drop in the ph of the sample. Even in short term storage conditions, samples may become acidified. This acidification can affect the integrity and reproducibility of samples, and may result in a loss of protein activity. VWR s CO 2 Resistant Tube is the only container closure system engineered to be CO 2 resistant and stop costly damage to molecular and cellular solutions when using dry ice. Made of durable, high quality materials and fitted with an air-tight cap, CO 2 Resistant Tubes form a protective barrier impermeable to CO 2, keeping the sample ph stable when shipping or storing on dry ice. CO 2 Resistant Tube caps feature a molded-in sealing ring that creates an air-tight secure seal and protects the sample from acidification by carbon dioxide. Air-Tight Caps PLACE YOUR ORDER TODAY AT VWR.COM, OR CALL VWR CO 2

3 VWR CO 2 FEATURES Air-tight caps have a unique elastomeric molded-in seal that protects samples from CO 2 exposure. Safely transport both large and small volume samples. CO 2 resistant tubes are an ideal vessel for primary and secondary containment. Max Freeze indicates the maximum suggested liquid volume for aqueous samples that will be frozen. Patented extra large writing panel shows contents in tube clearly, labels easily, and is smear resistant for permanent coding. IATA 95 kpa certification for shipping ensures containers are air-tight under different pressure conditions such as air transport. Easy to read graduations for accurate measurements. Thick, durable, medical grade resin withstands breakage when frozen. Samples in CO 2 Resistant Tubes should be frozen prior to dry ice exposure. PLACE YOUR ORDER TODAY AT VWR.COM, OR CALL VWR CO 2

4 Schedule of Activities: Tuesday, June 7th, 2016 PROTECTS SAMPLES FROM ACIDIFICATION Acidic Neutral Alkaline Other container closure systems do not provide a reliable barrier from CO 2 sublimating from dry ice. Carbonic acid formation will cause a decrease in ph by as much as 2.5 ph units. Acidification is seen as a color shift from blue to yellow in this experiment. OTHER TUBE 1 Drop in ph CO 2 RESISTANT TUBES No change in ph OTHER TUBE 2 Drop in ph ph 8 Upon thawing after dry ice ph changes seen as color shift from blue to yellow No change. CO 2 Resistant Tubes protect sample from CO 2 exposure. Change in ph. Other tubes do not protect sample from CO 2 exposure. CONTROL DRY ICE CONTROL DRY ICE CONTROL DRY ICE CO 2 Intrusion Test: Other Tubes vs. VWR CO 2 Resistant Tubes in Preventing ph Change of Sample Other Tubes vs. VWR CO 2 Resistant Tubes 80% Fill 40% Fill 20% Fill Sample ph % Fill 40% Fill 20% Fill ph Change EXPERIMENT: Pre-Frozen* tubes of buffered ph 8.0 solution were placed on dry ice for 48 hours. RESULTS: Carbon dioxide enters competitor tube headspace and acidification expands through the protein solution. FINDINGS: Only the CO 2 Resistant Tube protected the solution from acidification. *Samples in CO 2 Resistant Tubes should be frozen prior to dry ice exposure. PLACE YOUR ORDER TODAY AT VWR.COM, OR CALL VWR CO 2

5 VWR CO2 IDEAL CRYO CONTAINER FOR SMALL AND LARGE SAMPLE VOLUMES CO2 Resistant Tubes make an ideal vessel for secondary containment of small volume tubes. Since CO2 Resistant Tubes are IATA 95kPA certified for shipping they serve as a protective barrier against CO2 exposure, safeguarding small samples from costly damage. Most international and domestic carriers now require adherence to the IATA standards for all biological substance shipments. IATA 95kPa certification ensures the primary receptacle or secondary packaging is capable of withstanding, without leakage, an internal pressure producing a pressure differential of not less than 95kPa (0.95 bar, 13.8 psi). This standard ensures containers are resistant to leakage under differential pressure conditions such as those seen in air transport. Since air transportation is typically the most rigorous transport condition, containers that meet IATA regulations will also meet the requirements of other transport methods. CO2 Resistant Tubes ensure safe storage and transport of sensitive solutions in both large and small volumes. PLACE YOUR ORDER TODAY AT VWR.COM, OR CALL VWR CO2

6 Unique & Compact Packaging Sleeves of Ten 5 sleeves of 10 tubes ( tubes/pack, tubes/case) Validated secure package seal for sterility Can be separated and opened without scissors Leak resistant - can be immersed or sprayed with alcohol before opening, ensuring no contamination is present Every sub-pack is labeled with a lot number and sterile expiration date Perfect for working under the lab hood 15 ml CO2 Resistant Tubes Overall Length 118 mm Inside Diameter 15 mm Outside Diameter 17 mm Size Sterile Qty/Pk Qty/Cs 15 ml No Cat. No. 15 ml Yes Samples in CO 2 Resistant Tubes should be frozen prior to dry ice exposure. -80ºC to 110ºC ml CO2 Resistant Tubes Overall Length 115 mm Inside Diameter 25 mm Outside Diameter 29 mm Size Sterile Qty/Pk Qty/Cs ml No ml Yes ging Medical de Resin Gra and Packa Non-Pyrogenic Endotoxin Free Cat. No. CFR 21 USFDA COMPLIANT -80 C 7418_KK_WH M Lit. No