FLC - filling and closing machine for vials and infusion bottles

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1 FLC - filling and closing machine for vials and infusion bottles

2 FLC filling and closing machine FLC - versatile solutions for the medium output range Extremely flexible and reliable, meeting the highest technical standards with an excellent price/benefit ratio. With the FLC line, Bosch has expanded its product portfolio in the medium output range. The continuous motion machine provides a processing range with filling volumes of ml. A V-cleat conveyor system offers advantages in ease of size changeover. An innovative control system provides ease of use, high reliability and reproducible production settings. Output up to per hour The Laminar Flow (LF) infeed turnable was developed especially to meet aseptic production requirements. The containers are fed single-lane to the conveying system via the infeed star wheel.

3 Sizeparts. Central adjustment of transport system for different container sizes. Exchange of sizeparts without using tools. Transport system - flexibility via ease of size changeover Smooth handling of containers due to continuous motion of the transport system. The new linear conveyor system runs horizontally in continuous motion. The containers are carried freely in the LF stream, in an upright position. The containers are guided by interchangeable size components that are attached to the carrier system. The horizontal adjustment of the conveyor system allows containers with various diameters within a specified range of sizes to be processed without changing the size components. All sizeparts can be exchanged without tools : container size parts infeed 4-7: container size parts eject

4 Filling systems Depending on the product characteristics, four different filling systems are available: rotary slide valve pumps, a time-pressure filling system, rolling diaphragm pumps, and a filling station with mass flow metering. All systems can be optionally equipped with CIP/SIP (Clean-in-place/Sterilize-inplace). Precision filling is performed via programmable servo movements for pump stroke and filling needle movement. Filling programs can be stored an recalled via the control panel. 6-head filling station with rotary slide valve pumps in CIP/SIP version. Machine design tailored to the pharmaceutical industry, with a modular structure Fully automatic in-process weight control (IPC). The IPC system (optional feature) removes the containers in batches from the conveyor system for tare and gross weighing and then feeds them back into the system. If a trend in filling weight is detected, it is corrected by fully automated adjustment of the filling point. Rubber stopper feeding with reduced risk of particle contamination. The feeding of rubber stoppers from the supply hopper to the orienting bowl takes place via a feed chute that is even with the base of the orienting bowl ( Clean Feed ) Placement of stoppers on the vials is performed by a horizontally operating vacuum wheel. Fully automatic in-process weight control (IPC) with discharge of the containers in batches.

5 Good accessible operation via integrated touchscreen. FLC - the secure investment for the medium output range Key features: Easily accessible, compact structure. Outstanding price/performance ratio. Short delivery times due to modular machine structure. Flexible processing, ranging from 0.5 to 500 ml. Integrated LF infeed turnable with large central opening. V-cleat conveyor system with automatic container size changeover (optional feature). Size components can be used for a range of container diameters. Carrying container transport. Gentle motion of the container transport through filling and stoppering ensured by continuous mode of operation. Fully automatic in-process control (IPC) with automatic adjustment of the individual filling heads (optional feature). Batchwise removal of containers for tare and gross weighing. Stoppering station with Clean Feed delivery of stoppers to minimize the risk of particle contamination. Integrated control panel (touchscreen). FLC with closed RABS execution Installation variants: clean rooms, wall-mounted, RABS (Restricted Access Barrier System), isolator technology.

6 Technical data Containers: Injection vials and infusion bottles made of glass and plastic, up to 500 ml. Diameter mm Height mm Product: Pharmaceutical liquids (e.g. hydrous solutions, suspensions). Closures: Rubber stoppers (siliconized or teflonized) in mushroom or freeze dry version Fill range: up to 500 ml. Outputs subject to filling station: 4-head 6-head 8-head up to /h up to /h up to /h Illustrations in this leaflet are examples only! Binding data and specifications are contained exclusively in our individual quotation. All dimensions in mm. Subject to technical modifications. Locations world-wide Bosch Packaging Technology PA/MKT 01/06 1,0 E WA Iorio, Sulzbach Arnold, Deizisau Paper: natural white, without chlorine All rights reserved Headquarters Robert Bosch GmbH Packaging Technology Division Waiblingen Phone: Fax: pa@boschpackaging.com Brazil Sigpack Tecnologia de Embalagem Ltda. São Paulo Phone: Fax: sigpackbrazil@sigpack.com China Bosch Packaging Technology (Hangzhou) Co.Ltd. Hangzhou Phone: Fax: jens.mack@boschpackaging.com Denmark Moeller & Devicon A/S Sandved Phone: Fax: info@m-d.dk France Bosch Techniques d Emballage S.A.S. Reichstett Phone: Fax: pafr@boschpackaging.com Germany Robert Bosch GmbH Packaging Technology Division Product Division Pharma Liquid Crailsheim Phone: Fax: pa@boschpackaging.com Great Britain Bosch Packaging Services Ltd. Derby Phone: Fax: uk-hub@sigpack.com India Motor Industries Co.Ltd. Bangalore Phone: Fax: vtin@in.bosch.com Japan Bosch Packaging Technology K.K. Tokyo Phone: Fax: vtjp@boschpackaging.com Bosch Packaging Technology K.K. Chiba Phone: Fax: vtjp@boschpackaging.com Singapore Bosch Packaging Technology (Singapore) Pte. Ltd. Singapore Phone: Fax: sigpackasia@sigpack.com USA Bosch Packaging Technology Inc. Pharma Divison Minneapolis, MN Phone: Fax: sales@boschpackaging.com

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