Evolution of GM crop development from the 1990s to today; Future challenges: Pipeline products; Next generation GMOs and impacts on seed testing
|
|
- Henry Harris
- 6 years ago
- Views:
Transcription
1 Evolution of GM crop development from the 1990s to today; Future challenges: Pipeline products; Next generation GMOs and impacts on seed testing ISTA meeting, Montevideo, 2015 Dr. Ray Shillito, Bayer CropScience, USA Page 1
2 From the 1990s 1970 s to today; Page 2
3 Three key elements led to the first developments in Ag. Biotech Agrobacterium tumefaciens Plant Tissue Culture Molecular Biology and Biochemistry Page 3
4 The Initial Development of Plant Biotechnology occurred in the 70 s and 80 s in both the EU and USA. Page 4
5 Critical Technologies DNA discovered 1972 Discovery of restriction enzymes DNA cloning 1928 demonstration of bacterial transformation Structure of DNA solved 1976 DNA Sequencing Moratorium Southern blotting 1994 Agro transformation of Monocots 1984 Oligomer biosynthesis 1987 Gene Gun 1983 PCR invented Agrobacterium- transformation using disarmed vectors Transformation without Agrobacterium Page 5
6 Some of the Technologies with Direct Impact Selectable markers Tissue culture Protoplasts/PEG/electroporation Agrobacterium tumefaciens Biolistics Whiskers Agrobacterium in monocots A188 (3 way sweet corn cross) PCR Codon optimization Antisense / RNAi Bt proteins Cre/Lox etc. Page 6
7 Page 7 The view from 1996 was like this..
8 Key US Regulatory Approvals of Biotech Products 1992 FlavrSavr Tomato FDA 1994 Bt176, (EPA), 1995 (USDA, FDA) 1994 Bromoxynil cotton 1994 RR soybean (USDA), 1995 (FDA) NewLeaf Potato, USDA, EPA, FDA 1995 T25 LL Corn 1995 RR Canola 1995 Mon810 (USDA, EPA), 1996 (FDA) 1996 Papaya, Bt InVigor Canola (1996 in Canada) 1998 RR Sugarbeet (FDA), 2005 (USDA) 1999 LL62 Rice Page 8
9 Biotech Products and Cultivation in Europe Key Events 1997 Bt 176 Approved for cultivation 1998 Mon810 and T25 Approved for cultivation Food safety issues as a driver: First case of Mad cow disease in Europe Dioxin contamination (animal feed) scandal hits Belgium Coke products withdrawn in Belgium due to bad CO2 EU Moratorium on approvals Amflora potato approved for cultivation Page 9
10 Products that have come and Gone Although Approved Consumers may never see a product or not for long Demand for the FLAVR SAVR tomato was high and remained high, but the product was never profitable (because it wasn t in the right varieties and was difficult to get to market) Page 10
11 Page 11
12
13 Page 13
14 Global Area (Million Hectares) of Biotech Crops, 2014: by Country
15 Diversity of Biotech Products Others 1% Canola 9% Cotton 14% Maize 30% Soybean 50% Clara Rubenstein, Pioneer, a DuPont Company Major Biotech Crops Maize Soybean Cotton Canola Other Biotech Crops Sugar beat Alfalfa Papaya Eggplant Squash Potato Melon Sugarcane Wheat
16 Global Adoption Rates (%) for Principal Biotech Crops (Million Hectares, Million Acres), 2014
17 Country Value (USD million) Country Value (USD million) USA 12,000 Morocco 140 China 9,950 Switzerland 140 France 2,800 Bulgaria 120 Brazil 2,625 Chile 120 Canada 2,120 Nigeria 120 India 2,000 Serbia 120 Japan 1,350 Slovakia 110 Germany 1,170 New Zealand 100 Argentina 990 Uruguay 96 Italy 767 Ireland 80 Turkey 750 Paraguay 80 Spain 660 Portugal 80 Netherlands 590 Algeria 70 Russian Federation 500 Kenya 60 United Kingdom 450 Iran 55 South Africa 428 Israel 50 Australia 400 Tunisia 45 Republic of Korea 400 Bolivia 40 Mexico 350 Colombia 40 Czech Republic 305 Slovenia 40 Hungary 300 Peru 30 China, Taiwan 300 Zimbabwe 30 Poland 280 Malawi 26 Sweden 250 Libya 25 Romania 220 Saudi Arabia 20 Denmark 218 Zambia 20 Greece 200 Philippines 18 Belgium 185 Ecuador 15 Finland 160 Tanzania 15 Austria 145 Uganda 10 Egypt 140 Dominican Republic 7 Total USD 44,925 million (2013 figures) The commercial world seed market is assessed at approx. USD 45 billion Seed testing is important 6 of the top 10 commercial markets for seed are growing Biotech crops Data from: ISF 2014 ISAAA 2014
18 Page 18
19 Pipeline Products Page 19
20 Challenges for Agri-Businesses Limited arable land coupled with rising demand Safeguard and increase yields from constant land area better resource management (targeted use of crop protection, irrigation technology and fertilizers) increase yields through innovative technologies (hybridization, plant biotechnology) Expand agricultural production in marginal areas new crops with greater tolerance of drought and extreme temperatures Climate change Increase tolerance of plants to climatic variability develop new varieties using state - of - the - art technologies improve plant health and nutrient uptake Research and innovation are the key to mastering the challenges of the New Ag Economy Page 20
21 Industry investing in multiple modes of action, (as of 2014) CORN SOYBEANS COTTON WEED CONTROL ABOVE GROUND PESTS BELOW GROUND PESTS Glufosinate-tolerance Glyphosate-tolerance Imidazolinone-tolerance 2,4-D tolerance q FOP tolerance Glufosinate-tolerance Glyphosate-tolerance Sulfonylurea-tolerance q Dicamba tolerance q Glufosinate-tolerance Gen2 q HPPD tolerance q PPO tolerance Glufosinate-tolerance Glyphosate-tolerance q 2,4-D tolerance q Dicamba tolerance q HPPD tolerance Commercial offering Caterpillar protection Gen1 Caterpillar protection Gen2 Caterpillar protection Gen3 q Caterpillar protection Gen4 Caterpillar protection Gen1 Caterpillar protection Gen2 q Stink bug protection Bollworm protection Gen1 Bollworm protection Gen2 Bollworm protection Gen3 q Bollworm protection Gen4 q Lygus protection q Future or potential offering Rootworm protection Gen1 Rootworm protection Gen2 Rootworm protection Gen3 q Rootworm protection Gen1 q Soybean cyst nematode protection Root knot nematode protection Gen1 q Reniform nematode protection q Root knot nematode protection Gen2
22 Page 22
23 Page 23
24 Page 24
25 Page 25
26 Page 26
27 Page 27
28 Page 28
29 There are a lot of Events/Products! Crop Commer cial Events in 2008 JRC Projected Commercial Events in 2015 Possible Commercial products in 2014 Approved historically for cultivation (inc stacks) Approved historically for food (inc stacks) Soybean 1 17 ~ Maize 9 24 ~ Canola 4 10 ~ Cotton ~ Rice Potatoes Other Crops 7 23 ~ Flowers Total Source: 33 JRC Report, / ISAAA ~ ISAAA plus OECD database has 222 unique event entries
30 The wealth of new events has implications for ISTA members OECD (2013) ENV/JM/MONO(2013)19 Since it may be impossible to entirely eliminate LLP in seed, in some cases thresholds have been set to assure an acceptable and predictable supply of seeds. This has been in response to several instances where the LLP was detected at such a low level that it was technically below the level of quantification using validated protocols for testing. In these situations, testing at different stages in the seed distribution system led to conflicting results regarding the presence of LLP in seed. Recognizing the inability to entirely eliminate LLP, thresholds have also been adopted by some importing countries to avoid the reduced availability of seeds in cases where it was known that the unauthorized plant had been authorized at least in one other country.
31 The International community is discussing the issue of LLP in seeds The International Statement on Low Level Presence 12. Recognize that LLP of unapproved seed in commercial channels is also a challenge to seed trade and that it also requires collaborative efforts to address. Further collaborative efforts on seed through this initiative should be informed by the work being currently undertaken by the Organization for Economic Cooperation and Development (OECD) in this area List of countries endorsing the International Statement on Low Level Presence (2012) Australia, Argentina, Brazil, Canada, Chile, Costa Rica, Mexico, Paraguay, Philippines, Russia, United States, Uruguay, Vietnam.
32 Detection of unknowns is difficult Knut Heller, Genetically Engineered Food Methods and Detection, 2nd Edition, Wiley, 2006
33 GM testing which events? New events originating from major biotechnology providers New events arising from other sources Other events Stacked events Need efficient screening, identification and quantification methods which o are easily adaptable to the ongoing developments and o which can be easily introduced to existing laboratory infrastructures and testing schemes
34 Detection of stacks not possible Each individual event in a GM stack has a DNA or proteinbased detection method The inserted DNA of different events is usually located on different chromosomes or many millions of base-pairs apart on the same chromosome Event-specific PCR cannot bridge gaps greater than a few hundred base-pairs Therefore it is not possible with present technology to develop a molecular technique that detects the stack cf: recent EU study on analysis of stacks Page 34
35 Next generation GMOs and impacts on seed testing Page 35
36 New events are now arising from sources other than major biotech providers These come from small companies and/or government research. Products from major providers are registered in global markets Methods and reference materials are available Some other products are only registered in single countries or regionally and Methods and reference materials are not freely available Could present a challenge for detection in seeds Screening may be carried out based on knowledge of genetic elements present in the events (literature and other sources) Page 36
37 There were two main sources of early promoters: CaMV, Ti plasmid Page 37
38 The Modern Toolbox is Multidimensional: Tool DNA trait markers Benefits Can eliminate need for phenotyping of plants (MAB) Individual seed /plant testing Robotics Expression of introduced genes RNAi TALENs/CRISPRs Genome wide selection/ genotyping by sequence Page 38 Saves time/money/space/labor, increases breeding throughput Speed increase by integration of workflows in analysis of markers Biotech approach to add new genes (herbicide and insect tolerance) Biotech approach to alter biochemical pathways through the alteration of native gene expression Emerging techniques for the specific editing of native genes. Emerging technique enabled by cheap/fast DNA sequencing for the discovery of new markers for breeding, acceleration of backcrossing
39 Nucleases, TALENs and CRISPRs Chen and Lin: Promises and issues of GM crops, Current Opinion in Plant Biol., 2013 Page 39
40 Nucleases, TALENs and CRISPRs Generate ds breaks at specific locations in DNA which are repaired, leading to mutation-like changes From a detection point of view: The changes cannot be distinguished from mutations There is a discussion on whether and how these products might be considered regulated In any case we may need detection methods for purity testing Page 40
41 Detection of new GMO s Most regulations were written and adopted during a significantly simpler technology landscape. Today s reality may not have been anticipated. Screening assays based upon genetic elements will become less useful as new selectable markers, promoters and technologies are introduced. The costs and complexities to monitor seed purity will increase dramatically. Single event analysis remains methodology of choice 4 6 component stacks will become commonplace Increasing list of species as new technologies are adopted Change is inevitable
42 The Future Use of Agricultural Biotechnology continues to expand Many new events are being developed in multiple crops by both traditional biotechnology providers and new sources Events will originate from different global regions Stacked events will be more common and complex Products of newer technologies are a challenge to distinguish from natural processes Thus seed (GMOs) testing will become more complex and difficult It is important that global trade in seeds is not disrupted Reasonable Low Level Presence thresholds will be important in order to avoid trade disruptions
Pocket K No. 16. Biotech Crop Highlights in 2016
Pocket K No. 16 Biotech Crop Highlights in 2016 In 2016, the 21 st year of commercialization of biotech crops, 185.1 million hectares of biotech crops were planted by ~18 million farmers in 26 countries.
More informationWhat is Biotechnology?
What is Biotechnology? Biotechnology is a modern technology that makes use of organisms (or parts thereof) to: make or modify products; improve and develop microorganisms, plants or animals; or develop
More informationFSC Facts & Figures. September 1, FSC F FSC A.C. All rights reserved
FSC Facts & Figures September 1, 2017 FSC F0001000 FSC A.C. All rights reserved Global FSC-certified forest area North America 34.9% of total FSC-certified area ( 69,014,953 ha ) 246 certificates Europe
More informationUNIVERSITY OF KANSAS Office of Institutional Research and Planning
10/13 TABLE 4-170 FALL - TOTAL 1,624 1,740 1,926 2,135 2,134 2,138 2,246 Male 927 968 1,076 1,191 1,188 1,179 1,262 Female 697 772 850 944 946 959 984 Undergraduate 685 791 974 1,181 1,189 1,217 1,281
More informationGenetically Modified Organisms GMO - Update on Approval, Planting and Detection
Genetically Modified Organisms GMO - Update on Approval, Planting and Detection Ulf Rathjens 16.02.2018 www.eurofins.de Commercial Planting of GMOs 90% of global planting area in USA, Brazil, Argentina,
More informationPROS AND CONS OF GMO FOODS
PROS AND CONS OF GMO FOODS DUNAREA DE JOS UNIVERSITY OF GALATI 1 GMO s... organisms in which the genetic material has been altered in a way that does not occur naturally by mating and/or natural recombination
More informationSiemens Partner Program
Siemens Partner Program Factory Automation Partner Strategy for Factory Automation End Customer Focus on core competencies Demand on efficient solutions Certified Partner Added value in solutions and services
More informationDELIVERING A SYSTEM FOR HIGHER YIELD IN CANOLA
DELIVERING A SYSTEM FOR HIGHER YIELD IN CANOLA System of Solutions Come Together in Our Pipeline Development Process Monsanto s R&D Pipeline Designed to Address Farmers Challenges Increase Yield Impact
More informationRunning an RTB Network Across 10 Markets Publisher Opportunities ATTILA BARTA
Running an RTB Network Across 10 Markets Publisher Opportunities ATTILA BARTA Head Cadreon PROGRAMMATIC ADVERTISING THE SELLERS PERSPECTIVE The Strengths, Weaknesses, Opportunities and the Pitfalls for
More informationKeywords: Asparagus officinalis L., green asparagus, white asparagus, consumption, export, domestic, hemispheres, canned, fresh, frozen
2005 UPDATE OF THE WORLD S ASPARAGUS PRODUCTION AREAS, SPEAR UTILIZATION, YIELDS AND PRODUCTION PERIODS (To be published in the Proceedings of the XI International Asparagus Symposium in Acta Horticulturae)
More informationGLOBAL VIDEO-ON- DEMAND (VOD)
GLOBAL VIDEO-ON- DEMAND (VOD) HOW WORLDWIDE VIEWING HABITS ARE CHANGING IN THE EVOLVING MEDIA LANDSCAPE MARCH 2016 A CHANGING VIDEO-VIEWING LANDSCAPE Nearly two-thirds of global respondents say they watch
More informationGlobal Review of Commercialized Transgenic Crops: 2002 Feature: Bt Maize
I S A A A INTERNATIONAL SERVICE FOR THE ACQUISITION OF AGRI-BIOTECH APPLICATIONS EXECUTIVE SUMMARY Global Review of Commercialized Transgenic Crops: 2002 Feature: Bt Maize by Clive James Chair, ISAAA Board
More informationGMO Crops, Trade Wars, and a New Site Specific Mutagensis System. A. Lawrence Christy, Ph.D.
GMO Crops, Trade Wars, and a New Site Specific Mutagensis System A. Lawrence Christy, Ph.D. Background PhD in Plant Physiology from Ohio State University 12 years with Monsanto R&D in PGR s and herbicides
More informationAnalysis of Load Factors at Nuclear Power Plants
Clemson University From the SelectedWorks of Michael T. Maloney June, 2003 Analysis of Load Factors at Nuclear Power Plants Michael T. Maloney, Clemson University Available at: https://works.bepress.com/michael_t_maloney/10/
More informationGilflo ILVA Flowmeters
control & instrumentation solutions Gilflo ILVA Flowmeters for steam, liquids and gases E X P E R T I S E S O L U T I O N S S U S T A I N A B I L I T Y G i l f l o I L V A Gilflo ILVA Flowmeters for steam,
More informationPocket K No. 2. Plant Products of Biotechnology
Pocket K No. 2 Plant Products of Biotechnology Plant products of biotechnology have been available in the market for 21 years in 2016. These modified crops look like their traditional counterparts, but
More informationGLOBAL COALITION FOR GOOD WATER GOVERNANCE
GLOBAL COALITION FOR GOOD WATER GOVERNANCE Launched at the 2016 World Water Week in Stockholm, Sweden The OECD Principles on Water Governance On 4 June 2015, the OECD Principles on Water Governance were
More informationWHO PRODUCES FOR WHOM IN THE WORLD ECONOMY?
WHO PRODUCES FOR WHOM IN THE WORLD ECONOMY? Guillaume Daudin (Lille-I (EQUIPPE) & Sciences Po (OFCE), Christine Rifflart, Danielle Schweisguth (Sciences Po (OFCE)) 1 To be published in the Canadian Journal
More informationCountry CAPEXIL Description HS Codes Value Qty AFGHANISTAN TIS Asbestos cement pipes
Country-wise and Item-wise Exports of Cement, Clinkers and Asbestos Cement Products Value Rs. Lakh Quantity in '000 Unit: Kgs Source: MoC Export Import Data Bank Country CAPEXIL Description HS Codes Value
More informationGlobal management and control system of automatic doors for BRT systems (Bus Rapid Transit)
Global management and control of automatic doors for BRT s (Bus Rapid Transit) What is it? How does it work? What does it consist of? It is an integrated of automatic doors for BRT stations that synchronises
More informationGenetically modified pasture dairy s opportunity? Paula Fitzgerald
Genetically modified pasture dairy s opportunity? Paula Fitzgerald Global GM statistics 2013 cultivation 18 years old 175.2 million hectares of GM crops were planted 27 countries grew GM crops 19 developing
More informationCisco IT Data Center and Operations Control Center Tour
Cisco IT Data Center and Operations Control Center Tour Page 1 of 7 4 Root Cause Analysis and Change Management Root Cause Analysis Figure 1. Ian Reviewing Updates Ian: The incident management process
More informationBiosafety Regulation in Kenya
Biosafety Regulation in Kenya Prof. Theophilus M. Mutui, PhD Chief Biosafety Officer GM Food / Feed Safety Assessment Training Workshop for Regulators 7 th August 2014, KCB Leadership Center, Nairobi MISSION
More informationArgus Ethylene Annual 2017
Argus Ethylene Annual 2017 Market Reporting Petrochemicals illuminating the markets Consulting Events Argus Ethylene Annual 2017 Summary Progress to the next peak of the economic cycle, now expected by
More informationPyramid Research. Publisher Sample
Pyramid Research http://www.marketresearch.com/pyamidresearch-v4002/ Publisher Sample Phone: 800.298.5699 (US) or +1.240.747.3093 or +1.240.747.3093 (Int'l) Hours: Monday - Thursday: 5:30am - 6:30pm EST
More informationManage Centre. Manage your IT operations from a single graphical interface
Manage Centre Manage your IT operations from a single graphical interface One place where you can see all your technology Technology services are getting more complex all the time. Hybrid IT and cloud
More informationPotential impact of crop diversification and biotechnological inventions on the use of micronutrients
Potential impact of crop diversification and biotechnological inventions on the use of micronutrients Hillel Magen & Patricia Imas, ICL Fertilizers. Prophecy was given to fools = no more prophets available,
More informationAUDIT & ASSURANCE TAX & LEGAL CONSULTING CORPORATE FINANCE
AUDIT & ASSURANCE TAX & LEGAL CONSULTING CORPORATE FINANCE Proximity: relating to togetherness; being close in space and time. This is the characteristic that sets us apart. By drawing on the skills and
More informationDimension Data Managed Cloud Services for Microsoft
Dimension Data Managed Cloud Services for Microsoft Accelerate the benefits of Microsoft Office 365 and hybrid implementations with a full-service offering giving you all of the control, with none of the
More informationInternational Scholars and Faculty by College
OSU Colleges Agricultural Sciences 110 Business 9 Earth Oceanic and Atmospheric Sciences 44 Education 6 Engineering 127 Forestry 50 Liberal Arts 16 OSU Division Pharmacy 5 Arts & Sciences 82 Public Health
More information1 Introduction 2 BASF Crop Protection 3 BASF Plant Biotechnology Dr. Peter Eckes President, BASF Plant Science
1 1 Introduction 2 BASF Crop Protection 3 BASF Plant Biotechnology Dr. Peter Eckes President, BASF Plant Science The GM success story continues Global GM crop area in million hectares; 1 ha = 2.47 acres
More informationBioinformatics, in general, deals with the following important biological data:
Pocket K No. 23 Bioinformatics for Plant Biotechnology Introduction As of July 30, 2006, scientists around the world are pursuing a total of 2,126 genome projects. There are 405 published complete genomes,
More informationPuerto Rico 2014 SERVICES AND RATES
SERVICES AND RATES FedEx International Solutions for your business Whether you are shipping documents to meet a deadline, saving money on a regular shipment or moving freight, FedEx offers a suite of transportation
More informationEXECUTIVE SUMMARY. BRIEF 42 Global Status of Commercialized Biotech/GM Crops: Clive James Founder and Chair, ISAAA Board of Directors
I S A A A INTERNATIONAL SERVICE FOR THE ACQUISITION OF AGRI-BIOTECH APPLICATIONS EXECUTIVE SUMMARY BRIEF 42 Global Status of Commercialized Biotech/GM Crops: 2010 by Clive James Founder and Chair, ISAAA
More informationOutline. USAID Biotechnology. Biotech cotton, yield improvement and impacts on global biotechnology policy. Current Status & Impact of Biotech Cotton
Outline USAID Biotechnology Biotech cotton, yield improvement and impacts on global biotechnology policy John McMurdy, PhD Biotechnology Advisor US Agency for International Development March 5, 2009 Current
More informationCellular Therapy Products & NDC vs. ISBT128 Coding/Labeling
Cellular Therapy Products & NDC vs. ISBT128 Coding/Labeling William E. Janssen, Ph.D. Director, Cell Therapies Facility Moffitt Cancer Center Tampa, Florida What is ISBT 128? Information standard for blood,
More informationGlobal IT Procurement and Logistics. Simplifying the complex: an end-to-end IT supply chain solution
Global IT Procurement and Logistics Simplifying the complex: an end-to-end IT supply chain solution We make the complex simple Managing an international IT supply chain isn t an easy task, and comes with
More informationCUBE ENGINEERING. Wind energy with the focus on suppliers and provision of services, questions regarding the grid integration in Tunisia
Wind energy with the focus on suppliers and provision of services, questions regarding the grid integration in Tunisia CUBE ENGINEERING Engineering services for renewable energies Dipl. Landscape ecologist
More informationWhat are Genetically Modified Crops and how are they made? Professor Idah Sithole-Niang Department of Biochemistry, UZ GMASSURE - UZ
What are Genetically Modified Crops and how are they made? Professor Idah Sithole-Niang Department of Biochemistry, UZ GMASSURE - UZ Outline Definitions Concept of Genetic Modification Agricultural context
More informationCROP PRODUCTION AND BIOTECHNOLOGY: Successes and Challenges SUMMARY
CROP PRODUCTION AND BIOTECHNOLOGY: Successes and Challenges SUMMARY Background Different scientists have defined the term biotechnology. These definitions reflect the particular perspective of the scientists.
More informationProcess Maturity Profile
Carnegie Mellon University Process Maturity Profile Software CMM CBA IPI and SPA Appraisal Results 2002 Year End Update April 2003 We could not produce this report without the support of the organizations
More informationCibus. Harnessing the Power of Bio-Diversity. Cibus Rapid Trait Development system (RTDS ) is an environmentally friendly smart breeding tool.
Cibus Harnessing the Power of Bio-Diversity Cibus Rapid Trait Development system (RTDS ) is an environmentally friendly smart breeding tool. 1. Cibus Development stage company with offices located in San
More informationAppendix F. Electricity Emission Factors
Appendix F. Electricity Emission Factors F.1 Domestic Electricity Emission Factors, 1999-2002 Region / MWh) Methane Nitrous Oxide (1) New York, Connecticut, Rhode Island, Massachusetts, Vermont, New Hampshire
More informationRFID Systems Radio Country Approvals
SIMATIC Ident RFID Systems Radio Approvals 2017-12-17 www.siemens.com/ident Short Range Systems RF200 RF300 RF1060 MOBY D RF210R / RF220R 6GT2821-1AC10,-2AC10 RF210R / RF220R / RF240R/ RF250R/ RF260R IO-Link
More informationFedEx International Priority. FedEx International Economy 3
SERVICES AND RATES FedEx International Solutions for your business Whether you are shipping documents to meet a deadline, saving money on a regular shipment or moving freight, FedEx offers a suite of transportation
More informationPrecast solutions for tunnelling CBE GROUP
Precast solutions for tunnelling CBE GROUP A leading international company CBE GROUP IS A FRENCH INDUSTRIAL COMPANY, SPECIALIZED IN THE ENGINEERING AND THE MANUFACTURING OF METAL MOULDS AND INDUSTRIAL
More informationThe Challenges of [high-throughput] Phenotyping
The Challenges of [high-throughput] Phenotyping Mount Hood - sept 2008 Topics Introducing BASF Plant Science Phenotyping, for what purposes? What are the challenges? High-throughput phenotyping The TraitMill
More informationBeyond Promises: Facts about Biotech/GM Crops in 2016
Beyond Promises: Facts about Biotech/GM Crops in 2016 Biotech crop area increased more than 100-fold from 1.7 million hectares in 1996 to 185.1 million hectares in 2016. introduction Beyond Promises: Facts
More informationManoel T. Souza Júnior, Ph.D. Researcher A Embrapa AgroEnergy
Understanding The Non-Transformed Plant Manoel T. Souza Júnior, Ph.D. Researcher A Embrapa AgroEnergy manoel.souza@embrapa.br Adding Value via Genetic Engineering Gene Discovery Commercial Release Genetics,
More informationSwiss American Chamber of Commerce Global Trends in Employment. Patrick De Maeseneire, Chief Executive Officer Adecco Group
Swiss American Chamber of Commerce Global Trends in Employment Patrick De Maeseneire, Chief Executive Officer Adecco Group Agenda 1. Adecco at a glance 2. Seven global trends in employment 3. Our strategic
More informationInternational Business Parcels Rate card
International Business Parcels Rate card Tracked Effective from 3rd July 2017 Standard Tracked Tracked Signed Standard 1 Contents International Business Parcels services... 3 International Tracked... 4
More informationNatural Capital Accounting and the WAVES Global Partnership (Wealth Accounting and Valuation of Ecosystem Services)
Natural Capital Accounting and the WAVES Global Partnership (Wealth Accounting and Valuation of Ecosystem Services) Urvashi Narain The World Bank Cape Town, South Africa, October 27, 2013 What we measure
More informationMERCER LIFE SCIENCES COMPENSATION SURVEY
HEALTH WEALTH CAREER MERCER LIFE SCIENCES COMPENSATION SURVEY ASIA PACIFIC MAKE SMART COMPENSATION DECISIONS BY JOINING THE MERCER TOTAL COMPENSATION SURVEY FOR THE LIFE SCIENCES INDUSTRY THE LIFE SCIENCES
More informationFedEx International Priority. FedEx International Economy 3
SERVICES AND RATES FedEx International Solutions for your business Whether you are shipping documents to meet a deadline, saving money on a regular shipment or moving freight, FedEx offers a suite of transportation
More informationApplication from the World Federation of Chinese Medicine Societies for admission into official relations with WHO
EXECUTIVE BOARD EB136/NGO/6 136th session 6 November 2014 Provisional agenda item 13.3 Application from the World Federation of Chinese Medicine Societies for admission into official relations with WHO
More informationhp hardware support onsite global next day response
hp care pack hp hardware support onsite technical data hp hardware support onsite global next day response service overview benefits to you service highlights HP s global next day response service provides
More informationWholesale Gas Price Survey Edition
IGU - WHOLESAFE GAS PRICE FORMATION 2013 International Gas Union International Gas Union News, views and knowledge on gas worldwide Wholesale Gas Price Survey - 2013 Edition - A global review of price
More informationWorld BusinessTM.
www.atoz.com BUSINESS G L O B A L B U S I N E S S S I M P L I F I E D Conducting business across borders is both an opportunity and a challenge. Knowing how business is conducted in different countries
More informationGMO-Plants: Basics-Technology-Legislation-Analysis. Dr. F. Waldherr CONGEN Biotechnologie GmbH
-Plants: Basics-Technology-Legislation-Analysis Dr. F. Waldherr CONGEN Biotechnologie GmbH In September 2009 unauthorized linseed FP967/CDC Triffid from Canada was detected in europoean raw materials and
More informationCYBERTECH TOKYO //
TOKYO // 30.11.2017 CYBERTECH TOKYO // 30.11.2017 29.11.2017 // COCKTAIL RECEPTION 30.11.2017 // CONFERENCE AND EXHIBITION // THE NEW OTANI HOTEL, TOKYO CYBER // INNOVATION // ADVANCED TECHNOLOGIES //
More informationNew Brunswick agrifood. and seafood export. highlights
New Brunswick agrifood and seafood export highlights 2016 New Brunswick agrifood and seafood export highlights 2016 Province of New Brunswick P.O. Box 6000, Fredericton NB E3B 5H1 CANADA www.gnb.ca Printed
More informationThe Constant Pursuit of Petroleum Self Sufficiency
The Constant Pursuit of Petroleum Self Sufficiency Presentation to the FIESP 14th International Energy Meeting August 5th & 6th, 2013 Pennsylvania, 1859 Total Depth: 21.2m or 69ft Renato T Bertani President
More informationbenefits of bt cotton in burkina faso
Burkina Faso 2015 was the eighth year for farmers in Burkina Faso to benefit significantly from Bt cotton (Bollgard II ). The total Bt cotton planted in Burkina Faso in 2015 was 350,000 hectares, or 50%
More informationINTRODUCTION TO THE FEDERATION OF NATIONAL ASSOCIATIONS OF SHIP BROKERS AND AGENTS
INTRODUCTION TO THE FEDERATION OF NATIONAL ASSOCIATIONS OF SHIP BROKERS AND AGENTS Who are we, what do we do? FONASBA: The international shipbrokers and ship agents association, founded in London in April
More informationRegulation of Agricultural Biotechnology in the United States: Overview
Regulation of Agricultural Biotechnology in the United States: Overview Webinar for: National Agricultural Law Center July 15, 2015 Michael J. Firko, Ph.D. APHIS Deputy Administrator (BRS) History of Plant
More informationimpact the first nine years
GM crops: the global socioeconomic and environmental impact the first nine years 1996-2004 Graham Brookes & Peter Barfoot PG Economics Ltd, UK Dorchester, UK October 2005 Table of contents Executive summary
More informationProduct Catalog # Description List Price (JPY) Primer Assays (desalted)
Assays and Controls Primer Assay Pricing Primer Assays (desalted) 10025636 Primer assay desalted, 200 reactions 16,000 (Wet-lab validated human, mouse, and rat) 10025637 Primer assay desalted, 1,000 reactions
More informationAgriculture Commodity Markets & Trends
Agriculture Commodity Markets & Trends Agenda Short History of Agriculture Commodities US & World Supply and Demand Commodity Prices Continuous Charts What is Contango and Backwardation Barge, Truck and
More information3 rd WORLD CONFERENCE OF SPEAKERS OF PARLIAMENT
3 rd WORLD CONFERENCE OF SPEAKERS OF PARLIAMENT United Nations, Geneva, 19-21 July 2010 Item 2 SP-CONF/2010/2-R.1 1 July 2010 REPORT ON HOW PARLIAMENTS ORGANIZE THEIR WORK WITH THE UNITED NATIONS Rapporteur:
More informationBIO1PS 2012 Plant Science Topic 4 Lectures 2 and 3 Introduction to Plant Biotechnology
BIO1PS 2012 Plant Science Topic 4 Lectures 2 and 3 Introduction to Plant Biotechnology Dr. Michael Emmerling Department of Botany Room 410 m.emmerling@latrobe.edu.au Some Key Words Agrobacterium Ti plasmid
More informationGM crops: global socio-economic and environmental impacts
GM crops: global socio-economic and environmental impacts 1996-2008 Graham Brookes & Peter Barfoot PG Economics Ltd, UK Dorchester, UK April 2010 Table of contents Executive summary and conclusions...8
More informationIN BRIEF KEY FIGURES OF LAFARGEHOLCIM GLOBAL PRESENCE OF LAFARGEHOLCIM. Page 10. Page 16
IN BRIEF 9 KEY FIGURES OF Page 10 GLOBAL PRESENCE OF Page 16 10 Annual Report 2016 AT A GLANCE 52 % developing markets * 48 % mature markets * Balanced global footprint * of net sales 2,300 operating sites
More informationConcrete Waterproofing by Crystallization GENERAL CONSTRUCTION FOUNDATIONS
Concrete Waterproofing by Crystallization GENERAL CONSTRUCTION FOUNDATIONS Meeting the Challenge Protecting Foundations The structural integrity of building foundations, whether deep or shallow, can be
More informationCONVENTION FOR THE UNIFICATION OF CERTAIN RULES FOR INTERNATIONAL CARRIAGE BY AIR DONE AT MONTREAL ON 28 MAY 1999
State CONVENTION FOR THE UNIFICATION OF CERTAIN RULES FOR INTERNATIONAL CARRIAGE BY AIR DONE AT MONTREAL ON 28 MAY 1999 Entry into force: The Convention entered into force on 4 November 2003*. Status:
More informationVideo. Growing disparities in incomes among regions. A Degenerating Circle: Poverty, Environment & Economy. Are you able to Apply the Following:
Managing Biological Resources & Environmental Equality The Business of Hunger Now playing: Kurt Bestor, Sam Cardon Prayer of the Children A man who has bread has many problems, a man without bread has
More informationNASDAQ Investor Program. Jan Siegmund Chief Financial Officer
NASDAQ Investor Program Jan Siegmund Chief Financial Officer December 2013 Forward Looking Statements This document and other written or oral statements made from time to time by ADP may contain forward-looking
More informationDecision taken from September 2010 Four focus areas: megacities, informal sector, global recycling markets & international aid tools Members: Antonis
ISWA s Task Force on Globalization & Waste Management Decision taken from September 2010 Four focus areas: megacities, informal sector, global recycling markets & international aid tools Members: Antonis
More informationFedEx International Priority. FedEx International Economy 3
SERVICES AND RATES FedEx International Solutions for your business Whether you are shipping documents to meet a deadline, saving money on a regular shipment or moving freight, FedEx offers a suite of transportation
More informationUnapproved Genetically Modified Wheat Discovered in Oregon: Status and Implications
Unapproved Genetically Modified Wheat Discovered in Oregon: Status and Implications Tadlock Cowan Analyst in Natural Resources and Rural Development June 7, 2013 CRS Report for Congress Prepared for Members
More informationH E A L T H W E A L T H C A R E E R 2017 GLOBAL PAY SUMMARY
H E A LT H W E A LT H CAREER 2017 AT A GLANCE GEOGRAPHY 86 COUNTRIES COVERED 5 REGIONS 103 MARKETS Americas Asia Pacific Central & Eastern Europe Middle East and Africa Western Europe DATA INCLUDED ECONOMIC
More informationof improved open pollinated varieties and hybrid seeds in Pakistan.
biotech country Facts & Trends Pakistan In 2015, the adoption of insect resistant Bt cotton varieties in Pakistan increased to 93%. In 2015, Pakistan achieved a 93% adoption rate of Bt cotton, or 2.9 million
More informationThe Innovation Union Scoreboard: Monitoring the innovation performance of the 27 EU Member States
MEMO/12/74 Brussels, 7 February 2012 The Innovation Union Scoreboard: Monitoring the innovation performance of the 27 EU Member States This MEMO provides an overview of the research and innovation performance
More informationGlobal Overview of the Spread of Conservation Agriculture*
Global Overview of the Spread of * Amir Kassam, Theodor Friedrich, Rolf Derpsch, Josef Kienzle * Source: Kassam A., Friedrich T., Derpsch R., Kienzle J. (2014). Worldwide adoption of. 6 th World Congress
More informationGenetically modified sugarcane and Eldana. Sandy Snyman Agronomist s Association Annual Symposium 27 October 2015
Genetically modified sugarcane and Eldana Sandy Snyman Agronomist s Association Annual Symposium 27 October 2015 GM=Genetically modified What is GM? DNA/gene from one source is transferred to another organism
More informationLNG supply chain analysis and optimisation of Turkey's natural gas need with LNG import
World Maritime University The Maritime Commons: Digital Repository of the World Maritime University World Maritime University Dissertations Dissertations 2011 LNG supply chain analysis and optimisation
More informationEffects of Openness and Trade in Pollutive Industries on Stringency of Environmental Regulation
Effects of Openness and Trade in Pollutive Industries on Stringency of Environmental Regulation Matthias Busse and Magdalene Silberberger* Ruhr-University of Bochum Preliminary version Abstract This paper
More informationPerformance of the Self-Care Industry Current Trends and Future Expectations in Consumer Healthcare
Performance of the Self-Care Industry Current Trends and Future Expectations in Consumer Healthcare WSMI Sydney, 18-19 October 2017 Andy Tisman, Global Senior Principal Consumer Health QuintilesIMS Copyright
More informationCRO INDUSTRY GLOBAL COMPENSATION AND TURNOVER SURVEY
CRO INDUSTRY GLOBAL COMPENSATION AND TURNOVER SURVEY About the Survey The CRO Industry Global Compensation and Turnover Survey is entering its twentieth consecutive year. In 2017 it again had excellent
More informationInternational Energy Outlook 2011
International Energy Outlook 211 Center for Strategic and International Studies, Acting Administrator September 19, 211 Washington, DC U.S. Energy Information Administration Independent Statistics & Analysis
More informationTrade wreck? When ag policy meets reality. Jack A. Bobo Senior Advisor for Biotechnology U.S. Department of State
Trade wreck? When ag policy meets reality Hunger Today Hunger Tomorrow? Food Constraints Available Land Water Supply Technology Infrastructure Environment Policies Source: SOLAW, FAO 2011 Sustainable Intensification
More informationWATER PRICING Seizing a Public Policy Dilemma by the Horns
Water, Water Use & Water Pricing Around the World Introduction When discussing Canada s water supply and usage patterns, it is important to place Canada in a global context. Does Canada use more or less
More informationProduct Safety Assessment Herculex RW Rootworm Protection
Product Safety Assessment Herculex RW Rootworm Protection Select a Topic: Names Product Overview Manufacture of Product: Plant Transformation Process Product Description Product Uses Exposure Potential
More informationEvolution of Production Network: Measuring Trade in value-added (TiVA)
Evolution of Production Network: Measuring Trade in value-added (TiVA) Norihiko YAMANO Directorate for Science Technology and Industry, OECD Working Party on Globalisation of Industry Committee on Industry,
More informationGET TO KNOW GMOS A RESOURCE FOR YOU
GET TO KNOW GMOS GMO Answers was created to do a better job of answering consumers questions no matter what they are about GMOs. Our goal is to make information about GMOs in food and agriculture easier
More informationPART OF THE MAERSK GROUP
GLOBAL LOGISTICS INDIVIDUAL SOLUTIONS Damco is one of the world s leading providers of freight forwarding and supply chain management services For more than 100 years, we have been providing our customers
More informationKnowledge for Africa s Development: Innovation, Education, and Information and Communications Technologies Johannesburg, South Africa, May 8-10, 2006 DEVELOPING AND IMPLEMENTING KNOWLEDGE STRATEGIES EXPERIENCES
More informationHEALTH WEALTH CAREER ROTATOR ASSIGNMENTS: TRENDS, CHALLENGES, AND OPPORTUNITIES FOR ENERGY, ENGINEERING & CONSTRUCTION, AND MINING
HEALTH WEALTH CAREER ROTATOR ASSIGNMENTS: TRENDS, CHALLENGES, AND OPPORTUNITIES FOR ENERGY, ENGINEERING & CONSTRUCTION, AND MINING Changing demographics, security issues, government restrictions, talent
More informationSAMPLE. Bracco Imaging S.p.A.Market Share Analysis. Bracco Imaging S.p.A. Market Share Analysis GDME0639CDB / Published January 2013
Market Share Analysis Reference Code: GDME0639CDB Publication Date: January 2013 GlobalData. This report is a licensed product and is not to be copied, reproduced, shared or resold in any form Page 1 Table
More informationFedEx International Priority. FedEx International Economy 3
SERVICES AND RATES FedEx International Solutions for your business Whether you are shipping documents to meet a deadline, saving money on a regular shipment or moving freight, FedEx offers a suite of transportation
More informationBiotechnology Explorer
Biotechnology Explorer C. elegans Behavior Kit Bioinformatics Supplement explorer.bio-rad.com Catalog #166-5120EDU This kit contains temperature-sensitive reagents. Open immediately and see individual
More information