Brazilian Collection of Environmental and Industrial Microorganisms (CBMAI): Towards the Establishment of a Biological Resource Centre
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1 ICCC-12:Session 8B - Microbial Resource Centers: Quality Management Issues Brazilian Collection of Environmental and Industrial Microorganisms (CBMAI): Towards the Establishment of a Biological Resource Centre Lara D. Sette*, Fabiana Fantinatti-Garboggini, Milena B. Ferreira, Paulo M. Holanda Barros & Valéria M. Oliveira
2 History CBMAI was founded in the CPQBA (Campinas State University - UNICAMP) as part of the Division of Microbial Resources - DRM) Registered at WFCC WDCM Registered at CGEN as genetic resources depository deliberation n 81, November 18th, 2004 (MP ) Member of the Brazilian BRCs Network Project (FINEP ) 2008 Partner of the Demonstration Project for a Global Biological Resource Centre Network - German Federal Ministry of Research and Education (BMBF) Mission CBMAI is a service collection with the mission of acting as a BRC, doing research and offering quality services in the microbiological field for the industrial and academic sectors as for the society.
3 Institutional support CBMAI is officially recognized as part of the CPQBA/UNICAMP and it is included in the CPQBA strategic planning
4 Operation and Management International protocols (CABRI, OECD, WFCC) Data management system SICOL Quality system NBR ISO 17025:2005 OECD BPG for BRCs Quality Policy To maintain and ensure the quality of the researches and technical services provided by meeting the requirements of internationally recognized standards such as ISO/IEC 17025:2005 and OECD Best Practice Guidelines for Biological Resource Centres and by complying with national and international regulations and legislation. In order to achieve this, CBMAI is committed to continuous improvement of its activities
5 Biological material Bacteria, yeasts and filamentous fungi Risk groups 1 and 2 (WHO) Genetically Modified Organisms (GMOs) Risk groups 1 and 2 (CTNBio) Number of microorganisms in the collection Main collection = 1,200 strains 3% 5% 32% 35% bacteria filamentous fungi yeast 65% 60% Yeasts Research collection Filamentous fungi 50,000 metagenomic clones Bacteria 2,000 microbial strains extreme environments
6 Research Areas Isolation and screening Genomics and metagenomics Bioprospection CBMAI/ DRM Molecular ecology Preservation Systematics
7 CBMAI/DRM Research Ongoing Projects (11) 1 FINEP 1 ANNEL 3 PETROBRAS 3 CNPq 4 FAPESP Researcher staff Researcher = 3 Post-Doc = 2 PhD = 6 Master = 9 Technician = 3 Projects in negotiation (3) 1 European Community 1 FAPESP 1 PETROBRAS
8 ano base Services Deposit Distribution Preservation Counting Taxonomic characterization (molecular and conventional) Typing (genetic fingerprinting) Characterization of microbial communities from environmental samples (genetic fingerprinting and genomic libraries) Consultancy Progressão da arrecadação dos serviços Services progression crescimento
9 CBMAI/DRM Staff (CPQBA/UNICAMP) Prof. Dr. Ivo M. Raimundo Jr. Prof. Dr. Sérgio Persio Ravagnani Rita de C. V. P. Biancalana Sandra Maria Pierro Restani Damaris Batista da Silva Edilberto Prince Portugal Adilson Sartorato Cláudia Steckelberg Alexandre N. Ponezi Glyn Mara Figueira Auditors (6) Lidia Carmen Perez Dias Laura Suse Valock Alves Luís Otávio Martins Dr. Lara Durães Sette Dr. Fabiana Fantinatti-Garboggini Dr. Valéria Maia de Oliveira Milena Binatti Ferreira Samantha Gonçalves da Fonseca Giselle Kobata Kimura CPQBA Director CPQBA Associated Director Director Assistant Financial Supply CPQBA Integrated Management Coordinator Quality Manager Occupational Health and Safety Manager Environmental Manager Social Responsibility Manager Secretary Secretary Warehouse CBMAI Curator/DRM Researcher CBMAI Quality Mediator/DRM Researcher DRM Head and Researcher CBMAI Technician CBMAI Technician CBMAI Technical Support + 4 general services technicians and 1 computer assistant
10 Main Challenge from a service collection to a BRC
11 What is being doing Adequacy of infrastructure: CBMAI is changing the installations to a new facility (400 m 2 ) Biosecurity Biosafety Quality control Operation according to Brazilian legislation (biological material) Sampling Access Transportation
12 Quality management CBMAI is operating in accordance with the ISO requirements CBMAI is implementing OECD Best practice guidelines for BRCs
13 Next steps Implementation of liquid-nitrogen preservation method Back up of the main collection Staff increase Fully comply with the OECD Best Practice Guidelines for BRCs
14 Thanks! Support: Conselho Nacional de Desenvolvimento Científico e Tecnológico
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