Sustainability in Global Health Research the Research Fairness Initiative

Transcription

1 Sustainability in Global Health Research the Research Fairness Initiative Carel IJsselmuiden Global Health Transitions and Sustainable Solutions : the Role of Partnerships Public Private Partnership Forum, NAMES, Washington 13 June 2018

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3 Having research capacity that can be mobilized quickly and effectively in the countries where outbreaks are most likely to occur will be a prerequisite for the rapid deployment and testing of candidate products. The lack of such capacity will result in tragic delays, as in West Africa, where investigational Ebola vaccines and therapeutics were deployed far too late to impact the outcome of the epidemic.

4 In addition to all the impressive research advances in leading laboratories in the developed world, we need a world where those research and clinical capabilities are just as strong in the lower- and middle income countries where epidemics often strike. Without those capabilities, promising new interventions cannot advance as quickly as we need.

5 The International Vaccines Task Force (IVTF) has been created to boost the national capacity of low- and middle-income countries to seize those opportunities and to create the clinical research capabilities necessary to surge activity during emergencies and sustain those efforts in times of calm.

6 ensure the existence of a minimal and sustainable clinical research capacity to enable low and middle-income countries to collaborate and participate in late stage clinical trials themselves or with regional or international partners in the event of an epidemic. The Task Force believes this goal can be reached through strengthening internal country capacity as well as by working with regional research networks.

7 Partnerships essence of research

8 Two ways towards sustainable NHRS Longterm national vision, support, funding Partnerships

9 increasing research capacity developing comprehensive national research system support level of develop ment nature of intervention locus of intervention individual institution research system socioeconomic & political international collaboration & linkage 1 capacity building master level training grants manage-ment basis of NHRS increase demand for research good partnerships (e.g. Alignm & Harmonisation) 2 capacity strengthening doctoral level training merit-based promotion system research ethics review capacity civil society engagement fair research contracting 3 performance enhancement * equity-focus networking researchers, peer reviews research communication monitoring & evaluation of output and impact focus health, equity & soc-econ development focus on research competitiveness

10 Research Fairness Initiative The RFI is designed as an INSTITUTIONAL REPORTING SYSTEM on current practices and planned improvements in creating and maintaining research partnerships. It recognizes that partnerships are at the heart of research and innovation, and that we do not have a globally accepted framework of standards or benchmarks to design, operate or evaluate research and innovation partnerships.

11 RFI Reporting 1 Fairness of Opportunity - Before Research Fair Process During Research Fair Sharing of Benefits, Costs and Outcomes After Research

12 RFI Reporting 2

13 RFI Overview

14 Example RFI Domain 1 Fairness of Opportunity

15 Example RFI Domain 2 Fair Process

16 Example RFI Domain 13 Fair Sharing of Benefits, Costs & Outcomes

17 rfi.cohred.org

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19 RFI Impact Internal what are the benefits for the RFI Reporting Institution itself? External what are the benefits to your partners? National / Aggregated what is impact for LMICs? Global how will the RFI improve global research capacity and collaboration?

20 RFI - who is using it already? 1. RFI reports published WHO / TDR Senegal Univ Alioune Diop de Bambey Institute of Tropical Medicine and Hygiene, Lisbon 2. RFI reports near completion IRESSEF, Senegal CEA-SAMEF, Senegal 3. RFI reports started / starting Univ of Cape Town, South Africa Institute for Development Research (IRD), France 4. Expressions of Interest CPLP (Community of Portuguese Speaking Countries) Fiocruz (Brasil) Fudan University, Shanghai, China Emory University, School of Public Health, USA Johns Hopkins, Bloomberg School of Public Health, USA Amsterdam Institute for Global Health and Development, Netherlands Swiss Tropical and Public Health Institute (Swiss TPH), Switzerland McGill Univ, Department of Public Health, Canada UK Research and Innovation (UKRI), Grand Challenges Research Fund INSERM, France Tropical Diseases Research Centre, Zambia

21 Opportunity to showcase nonfinancial impact Reputational risk reduction / management Collaborative benefit possible cost reduction of research Provide support in line with core business and competencies rfi.cohred.org