CUSTOM PEPTIDE SYNTHESIS AT BACHEM

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1 CUSTOM SYNTHESIS

2 CUSTOM PEPTIDE SYNTHESIS AT BACHEM A strong commitment to quality is the basis of our long-standing market leadership We have the capability to synthesize peptides in mg to kg-scale which enables us to supply you with the quantities needed when your project develops As a global peptide partner we are collaborating with pharmaceutical, biotechnology, diagnostic, cosmetic companies, and academia Facilities are located in the US and in Europe including Bachem s center of excellence for catalog and custom peptides in St. Helens, UK Express Manufacturing service for urgent orders ISO certified manufacturing site in Vista, USA The excellent quality and the reliable service of Bachem are considered to represent key requirements for our progress in small-scale research projects and development programs. Big Pharma Company

3 LARGE SELECTION OF MODIFICATIONS N- and C-terminal Modifications Backbone Modifications Non-natural Amino Acids Glycosylation Lipidation Methylation Phosphorylation and Sulfation Cyclic Peptides Multiple Disulfide Bond Formation Maleimido and Clickable Peptides Hydrocarbon-Stapled Peptides Branched Peptides MAP Peptides Depsipeptides Peptidomimetics Our highly experienced custom synthesis teams with extensive know-how in sequence design and modifications will deliver every peptide in the quality you need.

4 PEPTIDE LABELING AND CONJUGATION Biotinylated Peptides Labeling with Tide Fluor TM and Tide Quencher TM Labeling with standard dyes and patented dyes Heavy Isotope Labeling FRET or TR-FRET Peptides Pegylated Peptides Conjugation to Imaging Agents Conjugation to Proteins: BSA and KLH Conjugation to Oligonucleotides Bachem is my primary source for synthetic versions of naturally occuring peptides. The Bachem range of ready-made synthetic peptides is extensive. I can be confident that Bachem will have my peptide of interest as full sequence, any biologically-relevant metabolites or variants of the peptide, as well as analogues, chemically modified forms and any pharmaceutical based on the natural peptide. Bachem will continue to be one of my most valued Research Partners. Big Pharma Company Bachem UK has been our major supplier of peptides for the last 33 years. During this period their products have always been of excellent quality, price and delivery. The staff at Bachem are extremely helpful and it has been a pleasure to do business with this company. University We re extremely pleased with Bachem s services. Bachem s employees are extremely knowledgeable and we highly appreciate their unusually customer-friendly support in all regards. It is a real pleasure working with them. Small Biotech Company I was very pleased with the service I received from Bachem. From start to finish, the communication was first-rate. I received quick (and patient!) responses to my numerous inquiries about my custom peptide, and they met their target date for delivery. Highly recommended. Small Biotech Company

5 Bachem - your partner for custom peptides. When your requirements advance from research scale to process development and cgmp manufacturing, we are ready to support you with our framework of cgmp production facilities and dedicated regulatory affairs staff.

6 ST. HELENS (UK) WEIL AM RHEIN (DE) VIONNAZ (CH) BUBENDORF (CH) VISTA (CA) TORRANCE (CA) GLOBAL BUSINESS Bachem facilities are located in Switzerland, the EU, and in the USA. All cgmp manufacturing sites are inspected by the US-FDA and national authorities. Marketing & Sales Contact Europe, Africa, Middle East and Asia Pacific Bachem AG Tel Americas Bachem Americas, Inc. Tel (toll free in USA & Canada) Visit our website or shop online shop.bachem.com All information is compiled to the best of our knowledge. We cannot be made liable for any possible errors or misprints. Some products may be restricted in certain countries. shop.bachem.com published by Global Marketing, Bachem Group, May 2016