Material Safety Data Sheet

Transcription

1 Material Safety Data Sheet NFPA HMIS Personal Protective Equipment 0 Health Hazard Fire Hazard 0 See Section 5. Section. Chemical Product and Company Identification Common Name/ Trade Name Manufacturer Fluorescein sodium SPECTRUM LABORATORY PRODUCTS INC S. SAN PEDRO STREET GARDENA, CA Catalog Number(s). CAS# RTECS TSCA F272, FL5, FL6, YY LM Page Number: T SCA 8 (b ) i n ve n t o ry: Fluorescein sodium Commercial Name(s) Synonym Chemical Name Chemical Family Chemical Formula Supplier Fluorescein, disodium; Fluorescein, disodium salt; C.I. Acid Yellow 73; Fluorescein, water soluble; Spiro[isobenzofuran-(3H),9'-[9H]xanthen]3-one,3',6'-dihydroxy-, disodium salt; Uranine; D&C Yellow No. 8 Fluorescein Sodium C20-H0-O5-Na2 SPECTRUM LABORATORY PRODUCTS INC S. SAN PEDRO STREET GARDENA, CA CI# CALL (30) IN CASE OF EMERGENCY CHEMTREC (24hr) Section 2.Composition and Information on Ingredients Name CAS # Exposure Limits TWA (mg/m 3 ) STEL (mg/m 3 ) CEIL (mg/m 3 ) % by Weight ) Fluorescein sodium Toxicological Data on Ingredients Fluorescein sodium : ORAL (LD50): Acute: 672 mg/kg [Rat] mg/kg [Mouse]. Section 3. Hazards Identification Potential Acute Health Effects Potential Chronic Health Effects Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. CARCINOGENIC EFFECTS: MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. TERATOGENIC EFFECTS: DEVELOPMENTAL TOXICITY: Repeated or prolonged exposure is not known to aggravate medical condition.

2 Fluorescein sodium Page Number: 2 Section 4. First Aid Measures Eye Contact Skin Contact Serious Skin Contact Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 5 minutes. Cold water may be used. Get medical attention. In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated clothing and shoes. Cold water may be used.wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention. Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention. Inhalation Serious Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Ingestion Serious Ingestion Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear. Section 5. Fire and Explosion Data Flammability of the Product Auto-Ignition Temperature Flash Points Flammable Limits Products of Combustion Fire Hazards in Presence of Various Substances Explosion Hazards in Presence of Various Substances Fire Fighting Media and Instructions Fire Hazards Explosion Hazards May be combustible at high temperature. CLOSED CUP: Higher than 93.3 C (200 F). These products are carbon oxides (CO, CO2). Some metallic oxides. Slightly flammable to flammable in presence of heat. Non-flammable in presence of shocks. Slightly explosive in presence of open flames and sparks. Non-explosive in presence of shocks. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet. As with most organic solids, fire is possible at elevated temperatures. Material in powder form, capable of creating a dust explosion. Fine dust dispersed in air in sufficient concentrations, and in the presences of an ignition source is a potential dust explosion hazard. Section 6. Accidental Release Measures Small Spill Large Spill Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.

3 Fluorescein sodium Page Number: 3 Section 7. Handling and Storage Precautions Storage Keep away from heat. Keep away from sources of ignition. Do not ingest. Do not breathe dust. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or the label. Avoid contact with skin and eyes. Keep away from incompatibles such as oxidizing agents, acids. Keep container tightly closed. Keep container in a cool, well-ventilated area. Section 8. Exposure Controls/Personal Protection Engineering Controls Personal Protection Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of a Large Spill Exposure Limits Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Section 9. Physical and Chemical Properties Physical state and appearance Molecular Weight ph (% soln/water) Solid. (Solid powder.) g/mole Odor Taste Color Odorless. Orange (Yellowish red) to Red. Boiling Point Melting Point 35 C (599 F) Critical Temperature Specific Gravity Vapor Pressure Not applicable. Vapor Density Volatility Odor Threshold Water/Oil Dist. Coeff. Ionicity (in Water) Dispersion Properties See solubility in water. Solubility Soluble in cold water, hot water. Section 0. Stability and Data Stability Instability Temperature Conditions of Instability Incompatibility with various substances The product is stable. Excess heat, excess dust generation, incompatible materials. Reactive with oxidizing agents, acids.

4 Fluorescein sodium Page Number: 4 Corrosivity Non-corrosive in presence of glass. Corrosivity Polymerization Will precipitate with acids. Will not occur. Section. Toxicological Information Routes of Entry Toxicity to Animals Chronic Effects on Humans Other Toxic Effects on Humans Toxicity to Animals Chronic Effects on Humans other Toxic Effects on Humans Eye contact. Inhalation. Ingestion. Acute oral toxicity (LD50): 4738 mg/kg [Mouse]. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. DEVELOPMENTAL TOXICITY: Classified Reproductive system/toxin/female [POSSIBLE]. Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation. May cause adverse reproductive effects (maternal) based on animal studies. May affect genetic material. May cause cancer (tumorigenic) based on animal studies. May cross the human placenta when applied to eyes as a topical opthalmic solution. It is excreted in human breast milk when applied to eyes as a topical opthalmic solution. Acute Potential Health Effects: Skin: May cause skin irritation. Eyes: Dust may cause eye irritation. Ingestion: High doses may cause digestive tract irritation including nausea, vomiting. May affect behavior, respiration (dyspnea), cardiovascular system, blood, and sense organs. Inhalation: Dust may cause respiratory tract irritation. Section 2. Ecological Information Ecotoxicity BOD5 and COD Products of Biodegradation Toxicity of the Products of Biodegradation the Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. The product itself and its products of degradation are not toxic. Section 3. Disposal Considerations Waste Disposal Waste must be disposed of in accordance with federal, state and local environmental control regulations.

5 Fluorescein sodium Page Number: 5 Section 4. Transport Information DOT Classification Not a DOT controlled material (United States). Identification Not applicable. Special Provisions for Transport Not applicable. DOT Section 5. Other Regulatory Information and Pictograms Federal and State Regulations California Proposition 65 Warnings Other Regulations TSCA 8(b) inventory: Fluorescein sodium California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer which would require a warning under the statute: No products were found. California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: No products were found. EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS No ). Canada: Listed on Canadian Domestic Substance List (DSL). China: Listed on National Inventory. Japan: Listed on National Inventory (ENCS). Korea: Listed on National Inventory (KECI). Philippines: Listed on National Inventory (PICCS). Australia: Listed on AICS. Other Classifications WHMIS (Canada) CLASS D-2B: Material causing other toxic effects (TOXIC). DSCL (EEC) R40- Limited evidence of a carcinogenic effect. Not available HMIS (U.S.A.) Health Hazard Fire Hazard 0 National Fire Protection Association (U.S.A.) Health 0 Flammability Personal Protection E Specific hazard WHMIS (Canada) DSCL (Europe) TDG (Canada)

6 Fluorescein sodium Page Number: 6 ADR (Europe) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Safety glasses. Section 6. Other Information MSDS Code References Other Special Considerations F3340 Validated by Sonia Owen on 6/3/2008. Verified by Sonia Owen. Printed 6/25/2008. CALL (30) Notice to Reader All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products, Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.