Agilent Press Conference June 6, Powerful Partnerships. Inspiring Outcomes

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1 Agilent Press Conference June 6, 2016 Powerful Partnerships. Inspiring Outcomes

2 Safe Harbor This presentation contains forward-looking statements (including, without limitation, information and future guidance on the company s goals, priorities, growth opportunities, financial performance and condition, including revenue growth, operating margin, free cash flow, earnings and capital allocation and deployment, the continued strengths and expected growth of the markets the company sells into, customer service and innovation plans, new product introductions, infrastructure and supply chain optimization, and operations) that involve risks and uncertainties that could cause results of Agilent to differ materially from management s current expectations. The words anticipate, plan, estimate, expect, intend, will, should forecast project and similar expressions, as they relate to the company, are intended to identify forward-looking statements. In addition, other risks that the company faces in running its operations include the ability to execute successfully through business cycles; the ability to successfully adapt its cost structures to continuing changes in business conditions; ongoing competitive, pricing and gross margin pressures; the risk that our cost-cutting initiatives will impair our ability to develop products and remain competitive and to operate effectively; the impact of geopolitical uncertainties on our markets and our ability to conduct business; the impact of currency exchange rates on our financial results; the ability to improve asset performance to adapt to changes in demand; the ability to successfully introduce new products at the right time, price and mix; and other risks detailed in the company's filings with the Securities and Exchange Commission, including our quarterly report on Form 10-Q for the quarter ended April 30, The company assumes no obligation to update the information in these presentations. These presentations and the Q&A that follows include non-gaap measures. Non-GAAP measures exclude primarily the impacts of acquisition and integration costs, future restructuring costs, transformational initiatives, asset impairment charges, business exit costs and divestiture, and non-cash intangibles amortization. Also excluded are tax benefits that are not directly related to ongoing operations and which are either isolated or cannot be expected to occur again with any regularity or predictability. Most of these excluded amounts pertain to events that have not yet occurred and are not currently possible to estimate with a reasonable degree of accuracy. Accordingly, no reconciliation to GAAP amounts has been provided..

3 Powerful Partnerships. Inspiring Outcomes. Agilent at ASMS 2016 Monty Benefiel Vice President /General Manager Agilent Mass Spec Division Jim Yano Vice President, Marketing Agilent Mass Spec Division

4 What Makes Agilent A Great Partner

5 It s About Mass Spectrometry But More than the Mass Spec

6 It s About Better Chromatography Systems and Consumables Routine analysis to cutting-edge research New 1260 Infinity II HPLC Broadest portfolio of LC systems and solutions Bringing more efficiency into the analytical lab Outstanding value proposition for upgrades and replacements

7 It s Definitely About More than Peaks and Spectra

8 It s About Sample Preparation Including Automation

9 Agilent Serves the Entire Analytical Lab Anticipating and responding quickly to customer needs Bioreagents Chemistries & supplies HPLC FISH probes Immunohistochemistry GC Mass Spec Spectroscopy Informatics Automation Vacuum CrossLab Consumables OpenLAB Software Platform CrossLab Services Microarrays Target enrichment

10 Agilent Technologies Receives Award for Outstanding Customer Service for Second Straight Year Agilent Technologies Inc. March 17, :00 AM SANTA CLARA, Calif.--(BUSINESS WIRE)-- Agilent Technologies Inc. (NYSE:A) today announced it has been recognized with the 2016 Reviewers Choice Award for Customer Service from SelectScience, an independent, expert-led scientific review. This is the second year in a row that SelectScience reviewers, which include scientists around the world, judged Agilent s customer service to be the best in the laboratory products industry. Powerful Partnerships. Inspiring Outcomes YES!

11 Our Partnership Is Focused on Their Complete Workflow Our Customers Are Focused on Their Molecules

12 Our Partnership Is Focused on Their Workflow Mass Spectrometry Software, software, software Chromatographic Separation Sample Preparation Our Customers Are Focused on Their Molecules Services

13 Agilent s Winning Strategy The World s Premier Laboratory Partner The Environment Chemical & Energy Food Pharma Academia & Government Clinical & Diagnostics $45B (1) Opportunity $13B (1) $22B (1) $10B (1) Inspiring Greater and Better Outcomes for Our Customers (1) Market sizes per Company estimates

14 Seahorse Extracellular Flux Analyzer Mitochrondrial fuel usage Cell energy phenotype test Mitochrondrial stress test Glycolysis stress test all in live cells

15 Cell Metabolism Measurements: Seahorse & MS Enabling breakthroughs in cancer research Agilent is a leader in Metabolomics Strong software suite and Mass Spectrometry platforms Seahorse acquisition strengthens our Metabolomics leadership Highly differentiated live cell metabolism measurements The combination of these research platforms enable major discoveries For example in cancer research &

16 Agilent at ASMS 2016 Powerful partnerships. Inspiring results. Saturday, June 4 Reception Integrating Metabolite Profiles for Less Impersonal Medicine Keynote speaker: Dr. Robert Gerszten Chief of Cardiology Beth Israel Deaconess Medical Center Visit the Agilent Booth #200 Breakout Sessions conducted by Agilent customers Track 1: Biological Research Track 2: Pharma/BioPharma Track 3: Applied Markets including Food & Environmental June 6-8 Breakfast Workshops June 6: Expand Your Metabolomics Horizons June 7: Better, Faster Agilent Solutions for Biopharmaceutical Characterization June 8: Food for Mass Spec Thought in the Applied Markets Daily 8am-11pm Agilent Hospitality Suite Grand Hyatt

17 Inspiring Outcomes Nagoya Institute of Technology Professor Hajime Ohtani MD Anderson Cancer Center Jennifer Molina & Pietro Morlacchi GC/MS Seahorse & LC/MS

18 What Are We Delivering to Our Lab Partners This Year? Agilent Confidential Sept Board Meeting 18

19 Understand Cellular and Molecular Metabolism Agilent Seahorse and Mass Spectrometry Together Cellular Metabolism Molecular Metabolism For Research Use Only. Not for use in diagnostic procedures.

20 Metabolomics: Accelerate Your Research With VistaFlux! Agilent s Qualitative Flux Analysis Workflow Pathways to PCDL PCDL Manager Create Target Metabolite List Acquire Data MassHunter Acquisition LC/TOF or LC/Q-TOF Profinder with VistaFlux Extract Features Visualize on Pathways Omix Premium VistaFlux Workflow For Research Use Only. Not for use in diagnostic procedures.

21 Flux Experiment Done by Justin Cross Cancer Cell Line with Enzyme Mutation (IDH2) Goal: Understand impact of mutation on glutamate metabolism Figure courtesy of Justin Cross, Donald B. and Catherine C. Marron Cancer Metabolism Center, Memorial Sloan Kettering Cancer Center Tracer experiment with U-13C-Glutamine (Gln) Monitoring metabolites labeled in green For Research Use Only. Not for use in diagnostic procedures.

22 Metabolomics dmrm Database and Method Integrated with Agilent s Metabolomics Workflows Dynamic MRM Database covers >215 central carbon metabolites Separate & Detect Quantitation Designed for 1290 Infinity II and 6460/6470 Triple Quadrupole MS Provides an optimized method and database with stable, robust chromatography LC/MS/MS Pathways Data Acquisition & Analysis MassHunter Statistics Pathway Architect Mass Profiler Professional For Research Use Only. Not for use in diagnostic procedures.

23 BioPharma: ADC DAR MassHunter Walkup Drug-Antibody Ratio for Reduced and Intact ADCs Non-expert LC/MS users can easily submit samples in MassHunter Walkup - completes Agilent s suite of products for an accelerated ADC characterization workflow

24 Pharma: Expanding Extractables & Leachables Confirmation of product purity > 800 compounds > 300 with exact mass Integrated into the All Ions workflow 6200 Series TOF & 6500 Series Q-TOF with 1260/1290 Infinity II LC Series Complements GC/MS and ICP- MS solutions

25 Proteomics: AssayMAP Bravo Target Customer Phosphopeptide Enrichment Digest Desalt Enrich Elute Clean up Analyze Scalable Reproducible Efficient Rapid Protein Digest Purify Desalt Alkylate Digest Clean up Analyze

26 Food: Safety in Numbers (Because More Matters) LC/TOF & LC/Q-TOF PCDLs > 1700 Pesticides > 2100 Veterinary Drugs > 450 Mycotoxins Free upgrades for 3 years

27 Environmental: Addressing Regulatory Requirements New LC/MS Analyzer New GC/MS Analyzer Water Screening PCDL Covers US, EU, China & Japan regulations > 1,400 compounds > 1,000 with exact mass 6200 Series TOF & 6500 Series Q-TOF Complements GC/MS and ICP-MS solutions Water Pollutant Screener Report templates compliant with European Water Framework Directive 2000/60/EC > 1,000 compound database with spectra and retention time 5977B Series GC/MSD (SQ)

28 GC/MS EI Source That Cleans Itself JetClean Patented Consistent response for weeks or months or years No downtime for source maintenance Available as an option or included with factory tested analyzers

29 Chemicals: Arsine/Phosphine Analyzer PE + PP >130 MMT In B GC/SQ HES: High Efficiency On-axis EI JetClean Arsine/Phosphine Analyzer Protecting catalyst efficiency for polyethylene and polypropylene production > Single digit ppb detection 300 runs, 4.6 days with % RSDs < 5%

30 The New Agilent 8900 Triple Quadrupole ICP-MS LEAVE INTERFERENCES BEHIND WITH MS/MS Superior Performance Controlled reaction chemistry for consistent, reliable results Resolution of isobaric overlaps (beyond capability of high-resolution ICP-MS) Lowest detection limits, even for previously difficult elements: S, Si, P Unparalleled Flexibility 4-channel cell gas control as standard Unique precursor/product ion scan modes clarify reaction processes

31 The new Agilent 1260 Infinity II LC! Leveraging 1290 Infinity II LC technologies for customer benefits! Time for YOUR technology refresh! Better in Every Way Sampling Solvent delivery Column handling Detection limits Ergonomics & safety Fully bio-inert Fully backwards method compatibility Poroshell InfinityLab Parts InfinityLab Columns Isocratic, Quaternary and Binary

32 Inspiring Outcomes Nagoya Institute of Technology Professor Hajime Ohtani MD Anderson Cancer Center Jennifer Molina & Pietro Morlacchi University of Arizona Professor Shane Snyder GC/MS Seahorse & LC/MS LC/MS, GC/MS & ICP-MS

33 Agilent s Partnership Goal Focus is always the customer Emphasis on solutions for the customer s workflow... not just mass spectrometers Any Analyte Any Method One Partner Automations Separations Mass Spec Supplies Software Applications CrossLab

34 Thank You

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