Development of a Portable Ultrasound Imaging System with Wireless Patient Monitor
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1 Development of a Portable Ultrasound Imaging System with Wireless Patient Monitor Won Seuk Jang The Graduate School Yonsei University Graduate Program of Biomedical Engineering
2 Development of a Portable Ultrasound Imaging System with Wireless Patient Monitor A Dissertation Submitted to the Graduate Program of Biomedical Engineering and the Graduate School of Yonsei University in partial fulfillment of the requirements for the degree of Doctor of Philosophy Won Seuk Jang August 2010
3 This certifies that the dissertation of Won Seuk Jang is approved. Thesis Supervisor: Nam Hyun Kim Thesis Committee Member: Nam Sik Chung Thesis Committee Member: Jin Bae Park Thesis Committee Member: Ha Suk Bae Thesis Committee Member: Sung Min Kim The Graduate School Yonsei University August 2010
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5 장원석올림
6 List of Figures iii List of Tables vi Abstract vii Chapter 1. Introduction Chapter 2. Portable Ultrasound Imaging Device Imaging algorithm for portable ultrasound imaging device Periodic sparse array Extended aperture System structure of the portable ultrasound imaging device Power supply for portable ultrasound imaging device Ultrasound smart probe Wireless smart probe Design ultrasound smart array and performance evaluation Manufacturing of the ultrasound smart probe Portable ultrasound imaging device based on embedded PC Chapter 3. Wireless Bio-Signal Measurement Module ECG design SpO 2 design NIBP design Temperature design Wireless interface of bio-signal measurement module Integrated wireless bio-signal measurement module i -
7 Chapter 4. System integration GUI Integrated portable diagnosis system Chapter 5. Result Chapter 6. Conclusion References 국문요약 ii -
8 Fig. 1 Example of the sparse and combination array Fig. 2 General model of the periodic sparse array Fig. 3 Images using periodic sparse array Fig. 4 Examples of the extended array Fig. 5 (a)general image (b)image using extended aperture Fig. 6 Block diagram of the portable ultrasound imaging device Fig. 7 Block diagram of the echo processor Fig. 8 Block diagram of the digital scan-line converter Fig. 9 Power circuit and battery Fig. 10 System structure of the smart probe Fig. 11 Developed 64 channels smart probe Fig. 12 Block diagram for wireless smart probe Fig. 13 Wireless smart probe Fig 14. Basic structure of the ultrasound array Fig. 15 Finite element analysis model and field analysis Fig. 16 Result of the simulation Fig. 17 Result of ultrasound field analysis Fig. 18 Result of the manufactured smart array pulse-echo test Fig. 19 Result of the measurement for beam characteristics in ultrasound smart array Fig. 20 Result of impedance measurement of the smart probe Fig. 21 Developed ultrasound smart probe Fig. 22 System structure of the portable ultrasound imaging device Fig. 23 Block diagram of Rx/Tx of the ultrasound and beamformer circuit iii -
9 Fig. 24 Connection of the smart probe, Rx/Tx and beamformer Fig. 25 Back-end of the ultrasound and embedded system board Fig. 26 Integrated portable ultrasound imaging device Fig. 27 Revised portable ultrasound imaging device Fig. 28 Block diagram for wireless bio-signal measurement module Fig. 29 Main processing diagram of the system Fig. 30 Overall structure of the main software Fig. 31 Block diagram of ECG hardware Fig. 32 Developed ECG board Fig. 33 Softwate flow of the ECG Fig. 34 The flow of QRS complex detection algorithm Fig. 35 QRS Detection of Arrhythmia Fig. 36 QRS detection in case of not using the pacer pulse detection at pacer pulse and QRS complex Fig. 37 QRS detection in case of using the pacer pulse detection at pacer pulse and QRS complex Fig. 38 System diagram of SpO Fig. 39 (a) Circuit of SpO 2 (b) Board of SpO Fig. 40 Software flow of SpO Fig. 41 Block diagram of the non-invasive blood pressure Fig. 42 (a) Circuit of the NIBP (b) Board of NIBP Fig. 43 Software flow of the non-invasive blood pressure Fig. 44 System diagram of the temperature Fig. 45 (a) Circuit of temperature (b) Board of temperature iv -
10 Fig. 46 Software flow of the temperature Fig. 47 BM-310 bluetooth chip Fig. 48 Block diagram for BM-310 module chip Fig. 49 Block diagram of UART between BM-310 module and MCU Fig. 50 Wireless bluetooth communication circuit Fig. 51 Wireless bluetooth communication board Fig. 52 Integrated wireless bio-signal measurement module Fig. 53 Basic concept of integrated portable diagnosis system Fig. 54 Basic design of display Fig. 55 Dispaly of the menu Fig. 56 Display part of bio-signal Fig. 57 Display part of ultrasound image Fig. 58 Display overlapped ultrasound image and bio-signal Fig. 59 Portable ultrasound imaging device combined with wireless bio-signal measurement module Fig. 60. Comparison of image of developed 32-channel system and commercialized 64-channel system Fig. 61 Image comparative evaluation of the commercialized 64-channel system and the developed system Fig. 62 Image comparative evaluation of the commercialized 64-channel system and the developed system Fig. 63 Color flow image from the developed system Fig. 64 Data viewer of the server in the hospital v -
11 Table 1 Power management mode of developed system Table 2 Structural variables of the ultrasound array and result of the design Table 3 Result of the characteristic measurement about 10 yield array Table 4 Performance improvement of the developed hardware system Table 5 The result of detection performance according to size and width of QRS complex Table 6 The result of QRS complex detection according to baseline change Table 7 Results of QRS complex detection performance of the arrhythmia Table 8 The result of pacer pulse detection performance at pacer pulse and QRS complex Table 9 Comparison image quality between developed 32-channel system and commercialized 64 channel system vi -
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26 Echo data US 8 bit FIFO & FIFO Controller & Data align CPU interface controller 32 bit US 16 bit 32 bit Data align & FIFO SDRAM (Echo data) 16 bit SDRAM controller ( Echo data ) SDRAM controller ( Pixel data ) 12 bit Address & Coefficient Generator 16 bit SDRAM0 (Pixel data) US 16 bit Data align 32 bit 8 bit Interpolator Data align 16 bit SDRAM1 (Pixel data)
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65 3.3 NIBP(Non-invasive Blood Pressure) Design It uses an oscillometric method that measures the maximum, minimum and mean blood pressure Hardware Design The design of NIBP is shown to Fig. 41, and each functions are as follows: l PRESSURE SENSOR: A sensor that detects the pressure inside the blood pressure cuff and changes it to the electrical signals l Solenoid Valve: Consists of two valves -- one is a valve for continuously reducing the pressure of cuff and the other is a valve for reducing the pressure at once l PUMP: An air pump for giving air pressure to cuff l ARM PROCESSOR: A CPU that operates blood pressure measuring algorithm l Safety PROCESSOR: Ensures a patient's safety if any fault occurs by cutting the power to make motor and valve stop Fig. 41 Block diagram of the non-invasive blood pressure
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