Weiss M, Weiss M, Lorden F, Trageser M, Beasley K. Picosecond laser for reduction of wrinkles: long term results.

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1 Marketing Bulletin November 2015 Dear Partner, Syneron Candela is pleased to announce the launch of Resolve, the holographic fractional Module for PicoWay. The introduction of the PicoWay Resolve handpieces positions PicoWay as the first and only picosecond device with dual fractional wavelengths, 532nm and 1064nm for both non-fractional and fractional modalities. PicoWay is the most comprehensive picosecond laser available, offering physicians the ability to treat pigmented lesions, tattoos of all colors and types, and treat skin and textural iregularities on all skin types. "Picosecond lasers are already being used for skin rejuvenation and improvement of acne scarring, using fractionated and non-fractionated beam profiles" 1,2. The Resolve Module consists of: 1. 2 fractional handpieces (532nm & 1064nm) 2. 4 distance gauges 3. A pack of 10 protective windows 4. An updated PicoWay User Manual 5. An updated PicoWay QRG 6. Software PicoWay Resolve Creates Skin Rejuvenation via LIOBs Resolve uses picosecond pulses to create laser induced optical breakdown (LIOBs) in the dermis while leaving the epidermis intact. This LIOB creation stimulates a healing response and skin remodeling, with no downtime. 3 1 Novel Dual-Wavelength, Nd:YAG, Picosecond-Domain Laser Safely and Effectively Removes Multicolor Tattoos, Eric F. Bernstein, et.al. Lasers in Surgery and Medicine, 2015 Wiley Periodicals, Inc. p1-7 2 Weiss M, Weiss M, Lorden F, Trageser M, Beasley K. Picosecond laser for reduction of wrinkles: long term results. 3 Minimally invasive non-thermal laser technology using laser-induced optical breakdown for skin rejuvenation, Louis Habbema et.al, Journal of Biophotonics 5, No. 2, (2012) 1 of 5

2 PicoWay with Resolve 5 Key Marketing Messages Provides dual wavelength (1064nm & 532nm) to target deep and shallow lesions. 1st and only aesthetic laser with revolutionary holographic fractional technology. Uses picosecond holographic fractional to deliver predictable energy and ensure uniform treatments. Customizes treatment of pigmentation, and skin and textural irregularities with adjustable fluences. Easy add-on to PicoWay. Two fractional wavelengths to treat all skin types 1064nm Treat deeper dermal lesions 1064nm fractional treatment screen Handpiece recognition in the software Blue ring with 1064nm printed on handpiece 532nm Treat shallower epidermal lesions 532nm fractional treatment screen Handpiece recognition in the software Red ring with 532nm printed on handpiece 1064nm for deeper lesions 532nm for shallower lesions Holographic fractional technology enables even energy distribution for consistent, effective treatment. 2 of 5

3 PicoWay Resolve Business Model The Resolve Module of PicoWay is a value packed, highly competitive product offering. It is unique because it offers both the 532nm and the 1064nm wavelengths to target different lesion depths and to enable treatment of all skin types, with no downtime. Equally important, Resolve utilizes a novel holographic fractionator which ensures even energy delivery across the spot size to enable consistent, reproducible results With these unique set of features, we have developed a special business model to enable customers to enjoy the full benefits of Resolve, affordably. The Resolve Business Model - Combines Purchase Price + Pay Per Pulse For New PicoWay Customers 1. Purchase Price: For new customers who purchase a PicoWay with Resolve, they will purchase the Resolve Module at a bundle price. (Your regional sales manager will inform you of the pricing for the bundle of PicoWay with Resolve.) 2. Pay Per Pulse : The customer will receive 1 million free pulses or one year of usage, the lesser of the two. After a year or 1 million pulses, the price per pulse will be a very nominal fee. (Your regional sales manager will inform you of the pricing for the pulses for the Resolve Module.) For Existing PicoWay Customers 1. Purchase Price: For existing PicoWay customers, they will purchase the Resolve Module at an attractive price. (Your regional sales manager will inform you of the pricing for the Resolve Module.) 2. Pay Per Pulse : The customer will purchase pulses at a very nominal fee from initial usage. (Your regional sales manager will inform you of the pricing for the pulses for the Resolve Module.) You will receive training on this Business Module so that you can easily walk your PicoWay customers through the value of this business opportunity. PicoWay Resolve Handpiece Specifications Laser Type Nd:YAG Frequency Doubled Nd:YAG Wavelengths 1064 nm 532 nm Micro-beam energy Up to 3.0 mj Up to 0.30 mj Pulse Duration 450 ps 375 ps Spot size 6mm x 6mm 6mm x 6mm Matrix 10x10 Micro-beam array 10x10 Micro-beam array Repetition Rate Single, 1,2,3,4,5,6,7,8,9,10 Hz Delivery System Articulated arm with Resolve handpieces 3 of 5

4 PicoWay Resolve Sales Tools and Practice Marketing Materials We have created a full complement of sales and marketing materials for the promotion of the Resolve. We encourage you to download and translate these PicoWay Resolve Sales Tools and Practice Marketing Materials for your local markets. Sales Tools Part # Picoway Product Brochure (revised) Resolve Mechanism of Action Video Resolve Product Ad Resolve Sales Roll Ups - 2 versions Resolve er Resolve Online Banners - 2 versions Resolve Sales Training Presentation PicoWay Sales to Physicians PPT PicoWay Physician Workshop PPT Clinical Marketing Clinical Training Presentation White Paper: "A new picosecond paradigm for prevention of tattoo and pigmented lesion removal induced adverse sequelae". David Friedman, M.D PicoWay User Manual (International version) PicoWay Quick Reference Guide (International Version) Resolve Press Kit Press Release Clinical Bulletin: "Mechanisms of action of fractionated 532nm and 1064nm picosecond laser for skin rejuvenation". Kevin Schomacker, Ph.D., Jayant D. Bhawalkar, Ph.D PicoWay Glossary (revised) Physician Testimonials (revised) Practice Marketing Resolve Patient Pamphlet Resolve Practice Enhancement Rollup Resolve Practice Enhancement Ad Resolve Rendered Handpiece Images Resolve Before and Afters Resolve Logo PB88551EN PB88561EN PB88571EN / PB88581EN _0A PB88521EN PB88911EN PB86192EN PB86013EN PB88591EN PB88821EN PB88831EN 4 of 5

5 The Resolve pages have been added to the Syneron Candela website and all materials have been uploaded to Partners-online into the PicoWay Resolve product folder. Sales and Clinical Training on the Resolve Module for PicoWay will be coordinated by your regional sales manager. Please contact either your regional marketing team or the Corporate marketing team with any questions regarding the Resolve Module for PicoWay. Good Selling! Sincerely, Ann Berzak Director, Aesthetic Products The Syneron-Candela Corporate Marketing Team PB88871EN 5 of 5