Results of Applications for the 2018 Integrated Thematic Projects at Academia Sinica Announced

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1 Results of Applications for the 2018 Integrated Thematic Projects at Academia Announced There is a total of 31 applications for the 2018 Thematic Projects (10 from Division of Mathematics and Physical Sciences; 18 from Division of Life Sciences; 3 from Division of Humanities and Social Sciences). The applications require a budget of NT$311,233,000 in total (NT$111,229,000 for Division of Mathematics and Physical Sciences; NT$184,746,000 for Division of Life Sciences; NT$15,258,000 for Division of Humanities and Social Sciences). 17 out of 31 applications were approved in the meetings of the Second-round Review and Budget Review, including 6 from Division of Mathematics and Physical Sciences, 8 from Division of Life Sciences, and 3 from Division of Humanities and Social Sciences. The total approved budget amounts to NT$122,939,000 (NT$45,000,000 for Division of Mathematics and Physical Sciences; NT$64,896,000 for Division of Life Sciences; NT$13,043,000 for Division of Humanities and Social Sciences). Please refer to the following table for detailed information. Approved projects may not be executed until budget plans are officially approved. A. Division of Mathematics and Physical Sciences: (6 projects) Project No. Title of Thematic Project (1) Project Director (2) Sub-project PI (3) Co-PI (4) Associate PI Institution AS-107-TP-A04 Electrical and Thermal Manipulations of Spin Transport in Spintronic Materials and Interfaces (1) SHANG-FAN Institute of Physics, Academia A04-1 Novel low-d quantum matters and magnetic heterostructures for spin transport (2) RAYNIEN KWO Institute of Physics, National Tsing Hua A04-2 To explore interface Rashba effect and high spin Hall ratio (2) SSU-YEN HUANG (3)CHI-FENG PAI Department of Physics, National Taiwan Department of Materials Science and Engineering, National Taiwan 04-3 Spintronics in antiferromagnets, ferromagnet/antiferromagnet bilayer (2) SHANG-FAN Institute of Physics, Academia AS-107-TP-A05 Cross-Lingual Cross-Document Knowledge Discovery at Micro and Macro Levels (1) KEH-YIH SU (3) HSIN-HSI CHEN Institute of Information Science, Department of Computer Science and Information Engineering, A05-1 Knowledge Exploration from Mono-Lingual Multiple Documents (2) KEH-YIH SU Institute of Information Science, A05-2 Knowledge Exploration from Multi-Lingual Documents (2) HSIN-HSI CHEN Department of Computer Science and Information Engineering, 1

2 A05-3 Linking Knowledge and End Users: Proactive Knowledge-Based Deep Text Generation A05-4 Knowledge Discovery and Prediction in Social Media (2) LUN-WEI KU Institute of Information Science, (2) CHENG-TE LI Department of Statistics, National Cheng Kung AS-107-TP-A06 Evolution and the Mechanism of Gene Dosage Buffering in Eukaryotes (1) HUAI-KUANG TSAI Institute of Information Science, A06-1 Genome-wide investigation of molecular mechanisms buffering gene expression (2) HUAI-KUANG TSAI Institute of Information Science, A06-2 The Mechanism of Gene Dosage Buffering during genome replication and in aneuploidy (2) CHENG-FU KAO Institute of Cellular and Organismic Biology, Academia AS-107-TP-A08 AS-107-TP-A09 A06-3 The Role of Nucleosomal Structures and Modifications in the Evolution of Polyploid Yeast Carbohydrate Structural Determination by IR Absorption, Mass Spectrometry, and High Level Quantum Chemistry Calculations, and Applications on Tumor-Associated Carbohydrate Antigen A08-1 Structural Determination of Carbohydrates by IR Absorption Spectra and Mass Spectrometry A08-2 Theoretical Studies on the IR Spectra and Dissociation Mechanism of Carbohydrates A08-3 Modularized Synthesis of Disaccharide Libraries for Carbohydrate Mass Spectrometry Validation and Synthesis of Tumor-Associated Carbohydrate Antigen Development of Multifunctional Organic Bioelectronic for Effective Neural Interfacing (2) JUN-YI LEU Institute of Molecular Biology, (1) CHI-KUNG NI Institute of Atomic and Molecular Sciences, (2) CHI-KUNG NI Institute of Atomic and Molecular Sciences, (2) JER-LAI KUO Institute of Atomic and Molecular Sciences, (2)CHENG-CHUN G WANG (1) PEILIN CHEN (3) HSIAO-HUA YU Institute of Chemistry, Academia Research Center for Applied Sciences, Institute of Chemistry, Academia 2

3 A09-1 Development of Multifunctional Conducting Polymer-based Bioelectronics for Promoting Neural Outgrowth and Controlled Release (2) HSIAO-HUA YU (3) SHYH-CHYANG LUO Institute of Chemistry, Academia Department of Materials Science and Engineering, National Taiwan A09-2 Fabrication and Characterization of Integrated Organic Electrochemical Transistors (2) YU-SHENG HSIAO (3) JING-JONG SHYUE Department of Materials Engineering, Ming Chi of Technology Research Center for Applied Sciences, A09-3 Applications of Organic Bioelectronic Devices for Neural Interfacing (2) PEILIN CHEN (3) DUENG-YUAN HUENG Research Center for Applied Sciences, Penghu Branch, Tri-Service General Hospital, National Defense Medical Center AS-107-TP-A10 Numerical Study of Microphysics and Dynamics of Deep Convective Clouds, Comparison with Satellite Data and Their Impact on Global Climate (1) PAO-KUAN WANG Changes, A10-1 Numerical Study on Ice Microphysics and Cloud Dynamics of Deep Convective Storms (2) PAO-KUAN WANG Changes, A10-2 Improvement of Overshooting Moisture Detrainment of Deep Convective Clouds in General Circulation Models and Its impacts on the Climate Simulations (2) HUANG-HSIUNG HSU (3) WEI-LIANG (3) CHEIN-JUNG SHIU Changes, Changes, Changes, A10-3 Intercomparison of deep convective cloud features as observed by satellite and their physics from cloud resolving model (2) CHIAN-YI LIU Center for Space and Remote Sensing Research, National Central B. Division of Life Sciences:(8 projects) Project No. Title of Thematic Project (1) Project Director (2) Sub-project PI (3) Co-PI (4) Associate PI Institution AS-107-TP-B02 Activation and In-activation of TE Transposition: Mechanism and Utilization (1) YUE-IE, CAROL HSING (4) ETIENNE BUCHER Institute of Plant and Microbial Biology, Institut de Recherche en Horticulture et Semences, INRA, France B02-1 The mechanism of activation and in-activation of rice Tos17 transposition (2) YUE-IE, CAROL HSING Institute of Plant and Microbial Biology, 3

4 B02-2 Rice TE-GWAS for large scale identification and exploitation (2) OLIVIER PANAUD Plant Genome and Development Laboratory, of Perpignan, France B02-3 An accelerated plant breeding process using TE (2) MING-HSIN LAI Crop Science Division, Taiwan Agriculture Research Institute AS-107-TP-B07 Mitochondrial Dynamics in the Control of Cellular and Tissue Functions (1) WEI-YUAN YANG Institute of Biological Chemistry, B07-1 Mechanistic study of the regulation of mitochondria dynamics and activity (2) CHUANG-RUNG CHANG Institute of Biotechnology, National Tsing Hua B07-2 Mitochondrial dynamics in the control of autophagy (2) WEI-YUAN YANG Institute of Biological Chemistry, B07-3 Mitochondrial dynamics in germline stem cell behavior and spermatogenesis (2) SHU YUAN YANG Department of Biomedical Sciences, Chang Gung AS-107-TP-B08 Synthesis and mechanistic study of pregnenolone derivatives that enhance neural activities B08-1 Function and Regulation of neurosteroid pregnenolone synthesis in the brain B08-2 Action mechanism of pregnenolone derivatives in vitro and in vivo B08-3 Functions of pregnenolone and its derivatives on memory and neurodegeneration in Drosophila B08-4 Investigate the roles of P5 and its derivatives on the development, regeneration and function of habenula circuit (1) BON-CHU CHUNG Institute of Molecular Biology, (2) SHIE JIUN-JIE Institute of Chemistry, Academia (2) BON-CHU CHUNG Institute of Molecular Biology, (2) SUE-WEI LIN Institute of Molecular Biology, (2) YUNG-SHU KUAN Institute of Biochemical Sciences, AS-107-TP-B11 Glycosidic Switch Liposomes for Effective Cancer Therapy (1) STEVE ROFFLER Institute of Biomedical Sciences, B11-1 Rational design of potent glycosidic switch liposomes (2) STEVE ROFFLER Institute of Biomedical Sciences, 4

5 B11-2 Development of a humanized bi-specific antibody (αepha2 α-mpeg) for specific targeting and endocytosis of glycosidic switch liposomes to EphA2-expressing metastatic tumors (2) TIAN-LU CHENG Department of Biomedical Science and Environmental Biology, Kaohsiung Medical B11-3 Synthesis of glycosidic switch cytotoxic drugs for nanoliposomal delivery to cancer cells (2) YU-LIN LEU Department of Pharmacy, Chia Nan of Pharmacy and Science AS-107-TP-B12 Synthetic Bioinspired Liposome Drugs for Targeted Cardiovascular Therapy (1) PATRICK C.H. HSIEH Institute of Biomedical Sciences, B12-1 Development of aptamer-conjugated liposome for monocyte-mediated myocardial infarction targeting (2) PATRICK C.H. HSIEH Institute of Biomedical Sciences, B12-2 Liposomal encapsulation methodology development for myocardial infarction reperfusion injury drugs and their trigger-release response to metalloprotease 2 (2) HSIEN-MING Institute of Chemistry, Academia B12-3 Development of cardiac intravital imaging system at the single cell resolution using two-photon microscopy (2) PEILIN CHEN Research Center for Applied Sciences, AS-107-TP-B15 From Exploiting Pancreatic Tumorigenesis to Developing New Therapeutics (1) CHIA-NING SHEN (3) WEN-HWA (4) CHUN-MEI HU B15-1 Genetic linkage analysis to search candidate genes in familial pancreatic cancer with whole exome sequencing /whole genome sequencing (2) MING-CHU CHANG Department of Internal Medicine, Hospital B15-2 Targeting pro-inflammatory cytokine Interleukin-17B/ Interleukin-17 receptor B (IL-17B/IL-17RB) pathway for pancreatic ductal adenocarcinoma treatment (2) WEN-HWA (4) CHUN-MEI HU (4) CHE MA (4) HAN-CHUNG WU (4) HENG-HSIUNG WU Institute of Cellular and Organismic Biology, Academia Graduate Institute of Biomedical Sciences, China Medical 5

6 B15-3 The roles of anti-inflammatory hormone glucocorticoids in pancreatic tumorigenesis and metastasis (2) CHIA-NING SHEN AS-107-TP-B16 B15-4 Architectural alteration in the inflammatory microenvironment of pancreatic cancer Studying the Signaling Complex Assembly of the Death Domain Superfamily Members in Innate Immunity, Apoptosis, Necroptosis and Pyroptosis, and its Relationships to the Activation of Downstream Molecules, and Their Electron Microscopic Investigations B16-1 Investigating the DED and CARD complex formation of the DISC and apoptosome and its relationship to caspase activation and their electron microscopic investigations B16-2 Investigating the DD complex formation and its relationship to enzyme activation in the Ripoptosome and Myddosome and their electron microscopic investigations (2) SHIUE-CHENG TANG (3) YU-WEN TIEN (3) YUNG-MING JENG (1) SU-CHANG LIN (2) SU-CHANG LIN Department of Medical Science, National Tsing Hua Department of Surgery; College of Medicine, National Taiwan Hospital Department of Pathology, National Taiwan Genomics, Research Center (2) YU-CHIH LO Biotechnology and Bioindustry Sciences, National Cheng Kung B16-3 Investigation of the cellular roles of DD-related complex assembly of the apoptosome, ripoptosome, DISC, and Myddosome in caspase and kinase activation (2) LI-CHUNG HSU Institute of Molecular Medicine, AS-107-TP-B18 Reconstructing a Holistic Picture of Austronesian Expansion and Migration by Integrating Archaeological, Biological, and Climatic Data (1) KUO-FANG CHUNG Biodiversity Research Center, B18-1 Reconstructing Austronesian expansion and migration using next-generation sequencing (NGS) data of paper mulberry (2) KUO-FANG CHUNG (4) CHI-SHAN CHANG Biodiversity Research Center, Division of Exhibition and Education, National Museum of Prehistory B18-2 Testing social relatedness with Lapita motif inventory (2) SCARLETT CHIU Institute of History and Philology, 6

7 B18-3 The Migration Investigation of Austronesian Peoples with Recent 30-year Global Daily Wind and Current Re-analysis Data and Paleo-climate Simulation Data (2) PO-HSIUNG LIN Department of Atmospheric Sciences, National Taiwan C. Division of Humanities and Social Sciences: (3 projects) Project No. Title of Thematic Project (1) Project Director (2) Sub-project PI (3) Co-PI (4) Associate PI Institution AS-107-TP-C01 Indigenous People, State and Governance:Comparative Austronesian Perspectives C01-1 State Governance and Indigenous People's Traditional Territory: A Comparative Study of the Philippines and Taiwan (1) Pei-Yi Guo Institute of Ethnology, Academia (2) Shu-Yuan Yang Institute of Ethnology, Academia C01-2 Governing Natural Resources and Developing Indigenous Settlements: A Case Study of the Tayal Settlements in Jianshih Township, Hsinchu County (2) Kuang-Chi Hung (3) Da-Wei Kuan Department of Geography,. Department of Ethnology, National Cheng Chi AS-107-TP-C02 C01-3 Governmentality and Subjectivity in a Financial Market: A Case Study of the Rukai of Taiwan C01-4 Urban Indigenous Peoples and Local Governance: The Case of the Danman Amis C01-5 The Entanglement of intellectual and cultural property rights C01-6 Cultural Heritage and Cultural Governance in Contemporary Oceania A Comparative Study of the Chinese Nationalist Party and the Communist Party of China C02-1 A comparative study of Chiang Kai-shek and Mao Zedong's foreign policies for the Great Powers: Focusing on the Post-WWII Take Over of Northeast China (2) Weining Cheng Institute of Ethnology, Academia (2) Wen-Te Chen Institute of Ethnology, Academia (2) Kai-Shyh Lin Department of Anthropology, (1) Pei-Yi Guo Institute of Ethnology, Academia (1) Tzu-Chin Huang Institute of Modern History, (2) Tzu-Chin Huang Institute of Modern History, 7

8 C02-2 The Historical Interoperations of the Revolution of 1911 and the Struggle over Orthodoxy of Revolution between The Chinese Nationalist Party(Kuomintang, KMT)and The Chinese Communist Party C02-3 The Nationalist Party and the Chinese Communist Party in the Eyes of the Third Force C02-4 KMT and CCP s Ethnic Politics: A comparative Study ( 1905~1965 ) (2) Kwang-Che Pan Institute of Modern History, (2) Ko-Wu Huang Institute of Modern History, (2) Zhe Wu Institute of Modern History, C02-5 KMT and CCP s Cadre Education: A Comparative Study from the Perspective of Political Infrastructures (2) Chen-Cheng Wang Institute of Modern History, C02-6 A Comparative Study of the Principles of Governing the Country after the The Chinese Civil War (2) Wei-Kai Liu Department of History, National Cheng Chi C02-8 A Comparative Study of the Party Culture of the KMT and the CCP: Meeting, Paper Work, and Communication (2) Yoshihiro Ishikawa The Kyoto Research Centre for the Cultural Sciences, Japan C02-9 Comparative study on internal party democracy of Kuomintang and Chinese Communist Party C02-10 The Change of the Contemporary Chinese Politics and the Redefining of Mao Zedong Thought C02-12 A Comparative Study on the Army s political maneuvering of the KMT and the CCP, in 1940s C02-13 Organization and Resources: Competition between the KMT and the CCP on the second sino-japanese war till the Civil War (2) Kenji Eda Kyoto Faculty of Integrated Human Studies of Human and Environmental Studies, Japan (2) Hitoshi Tanaka School of Law and Politics, Osaka, Japan (2) Qisheng Wang Department of History, Peking, China (2) Daoxuan Huang Institute of Modern History, Chinese Academy of Social Sciences, China 8

9 AS-107-TP-C03 Empire and Civilization: Critical Reflections on the Formulation of Universal Values (Europe: ) C03-1 British Ideas of Empire and Civilization C03-2 The Spirit of Freedom and the Spirit of Democracy in Imperial Perspective: Comparisons between Burke s and Tocqueville s Ideas of Civilization C03-3 Classical Utilitarianism s Ideas of Imperialism and Civilization: A Study on Bentham, James Mill and John Stuart Mill C03-4 Republicanism and Empire: On Rousseau and His Influences C03-5 Liberalism and Empire: On Locke and Kant C03-6 Hegel's Philosophy of History as a Discourse of Civilization (1) Kuo-Shiang Roy Tseng Research Center for Humanities and Social Sciences, Academia (2) Jeng-Guo Chen Institute of History and Philosophy, (2) Kuo-Shiang Roy Tseng Research Center for Humanities and Social Sciences, Academia (2) Hao Yeh Department of Politics, National Cheng Chi (2) Chia-Ming Chen Research Center for Humanities and Social Sciences, Academia (2) Chia Yu Chou Department of Public Administration and Policy, National Taipei (2) Carl K. Y. Shaw Research Center for Humanities and Social Sciences, Academia 9

IAM2016W Program. January 27, 2016 (Wednesday) 15:00-16:30 Registration (Lobby) January 29, 2016 (Friday) 09:30-15:00 Registration

IAM2016W Program. January 27, 2016 (Wednesday) 15:00-16:30 Registration (Lobby) January 29, 2016 (Friday) 09:30-15:00 Registration IAM2016W Program January 27, 2016 (Wednesday) 15:00-16:30 Registration (Lobby) January 28, 2016 (Thursday) 09:30-15:00 Registration 10:00-12:00 Session A 13:30-15:30 Session B January 29, 2016 (Friday)