Per Morten Sandset Japan-UiO cooperation within health and care research status and opportunities

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Per Morten Sandset p.m.sandset@medisin.uio.

1 Per Morten Sandset Japan-UiO cooperation within health and care research status and opportunities

2 Japan-UiO cooperation within health and care Brief presentation of the University of Oslo (UiO) Ongoing collaboration(s) between Japan and UiO Some examples and opportunities

3 staff

4 Worlds 62nd best university Shanghai Ranking of World Universities

research, education and innovation Recruit, educate and develop talents Promote innovation in the life sciences

9 UiO:Life Science Strategy convergence The planned life science building Strengthen quality and interaction in research Solve grand challenges, value creation & international competitiveness A new arena for collaboration in research, education and innovation Recruit, educate and develop talents Promote innovation in the life sciences related to environment and health and closer collaboration with hospitals and businesses A resource for the whole Oslo region

10 The life science building 2024 Norway s largest university building Department of Chemistry School of Pharmacy Centre for Molecular Medicine Norway (NCMM) & interdisciplinary life science research groups

11 Japan-UiO cooperation within health and care Brief presentation of the University of Oslo Ongoing collaboration(s) between Japan and UiO Some examples and opportunities

12 UiO Japan overall research performance

13 Japan-UiO cooperation within health and care Brief presentation of the University of Oslo Ongoing collaboration(s) between Japan and UiO Some examples and opportunities Physics and radiosotopes Life science School of dentistry

14 Radiumhospitalet National Cancer Hospital: Planned proton therapy center in Oslo Radiotherapy building (2006) New clinic Research building (2008) Proton therapy center

15 Research topics preclinical research Radiation Biology effects of protons compared to conventional X-rays Tumor and normal tissue effects Combinatory treatment (e.g. chemotherapy or immunotherapy + proton therapy) Biomarker-based treatment outcome prediction Radiation and medical physics Detector development New principles for quality assurance New proton beam control systems Basic radiation physics

16 Dementia research with PET From development of new radiolabelling reactions To clinical trials with a radiotracer for dementia

18 Flavours of Pluripotent Stem Cells

19 Why do we need hepatocytes? Toxicity Screening Disease Modelling Bio-artificial Liver Malaria & HCV Transplantation

Stem Cell Research (prof J Glover) Norwegian Bone Marrow Donor

20 Interaction (consultant basis) on development of a Norwegian clinical biobank of allogeneic ips cells Norwegian Center for Stem Cell Research (prof J Glover) Norwegian Bone Marrow Donor Registry Kyoto University Center for ips Cell Research and Application (CiRA)

Hybrid Technology Hub (Director and Prof. Stefan Krauss) Center of Excellence htpp://www.med.uio.

21 Hybrid Technology Hub (Director and Prof. Stefan Krauss) Center of Excellence htpp:// Department of Molecular Medicine, Institute of Basic Medical Sciences The goal: cross-disciplinary international Hybrid Technology Hub is to develop organ on a chip platform that reproduces core functionalities of the human body. allows real time data acquisition upon exposure to therapeutic reagents current focus is on energy metabolism regulating organs. Main research fields: Microfluidic carrier platform Sensor systems and imaging Organoid systems Drug testing Bioinformatics Ethics The Hybrid Technology Hub Centre of Excellence is divided into 11 research groups, that will contribute to one or more of the centre's six research topics.

22 Faculty of Mathematics and Natural Sciences Faculty of Medicine Faculty of Social Sciences Faculty of Humanities (IFIKK) Museum of Cultural History Interdisciplinary research groups convergence environments Combining natural and social sciences to understand and manage global anthropogenic toxicants (AnthroTOX) Epigenetics and bioethics of human embryonic development Programmable Cell-like Compartments Comparative immunology of fish and humans (COMPARE) Organ on a chip and nano-device (CHIP) Personalised cancer therapies (PERCATHE) The genetic history of Eastern Eurasia (ARCH-GEN)

23 School of Dentistry Biomaterials Cell Engineering Division, RIKEN BioResource Center, Tsukuba, Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki Surgery/imaging Nihon University, Tokyo (K Honda) Jikei University, Tokyo (K Hayashi) Osaka Dental University (Y Yotsui)

Health Information Systems Program HISP a global action research network initiated in collaboration with University of

DHIS 2, District Health Information Software, is an open source software for reporting, analysis and dissemination of

Aggregate, events, and patient data Generic and generative platform - supports a wide range of uses also beyond the

24 Health Information Systems Program HISP a global action research network initiated in collaboration with University of Western Cape in 1994 funded by Norad. DHIS 2, District Health Information Software, is an open source software for reporting, analysis and dissemination of data for all health programs Shared and integrated data warehouse for essential health data: information for action Aggregate, events, and patient data Generic and generative platform - supports a wide range of uses also beyond the health sector Financed and endorsed by all Global Health agencies, WHO, Norad, CDC, PEPFAR, Unicef, Gates Foundation, USAID, Global Fund, GAVI DHIS2 used in 88 countries in the Global South Dec 2017: WHO collaborating Centre

HISP - action oriented multidisciplinary research Strengthening national health information systems Collaborating with Ministries of Health Participatory design (Scandinavian tradition) Action

25 HISP - action oriented multidisciplinary research Strengthening national health information systems Collaborating with Ministries of Health Participatory design (Scandinavian tradition) Action Research: Building knowledge on implementing HIS while building systems on the ground through partnerships. PhD school: 48 PhDs graduated International Masters programs in South Africa, Mozambique, Malawi, Tanzania, Ethiopia, Sri Lanka total 400 graduated

26 Scientia Fellows postdoctoral mobility program EU, Horizon 2020 COFUND, Marie Curie Program 125 postdoc fellows Incoming postdoctoral fellowship (12-36 months) Outgoing postdoctoral fellowship (12-36 months) Project period:

27 The overall objectives A program worldwide in the area of Health Life Sciences Provide excellent research environments and infrastructure Provide interaction between academia and health technology industry/clusters with SMEs. Provide a training program designed to maximize the career prospects of the researchers by the development of translational, multidisciplinary research skills along with transferable skills including entrepreneurship, dissemination and management.

28 Scientia Fellows

Promoting collaboration: Strategies and programs within health research and innovation

Promoting collaboration: Strategies and programs within health research and innovation Anne K Fahlvik, PhD, Executive director Mari K Nes, PhD, Special Adviser The Research Council of Norway The Research