The Cryptic Path to Your Future. Cryptic Masons Medical Research Foundation

Transcription

1 The Cryptic Path to Your Future Cryptic Masons Medical Research Foundation

2 General Grand Council, Cryptic Masons, International

3 Your General Grand Council, Cryptic Masons, International and Cryptic Masons Medical Research Foundation is Advancing the Scope of Atherosclerosis Research with the Cryptic Masons Chair in Vascular Biology Research.

4 Purpose of CMMRF Research is BECAUSE Cardiovascular disease is the Number One Killer in the United States. You Know Someone Who s had a Heart Attack or Stroke. You Are Committed to Improving Medicine for Future Generations. YOU CARE.

5 Cryptic Masons Medical Research Foundation Since January 1, 1986 all contributions have been cumulative. Located at Indiana University, Indianapolis, Indiana. Many recognition levels for donations. Donations are tax deductible. Your Donations will live forever. They are Never spent.

6 Indiana Center for Vascular Biology& Medicine(ICVBM) Cryptic Masons Medical Research Center Indiana University, Indianapolis,Indiana

7 Our Mission Statement The Indiana Center for Vascular Biology and Medicine (ICVBM) is committed to the rapid development, testing and extension to clinical application and commercialization of new knowledge in vascular biology. The ICVBM operates with the purpose of promoting research while impacting delivery of novel and innovative medical treatment in order to achieve positive results within the health care community.

8 You & Your General Grand Council, Cryptic Masons, International Have Already Accomplished With the ICVBM the Following for Vascular Biology: 1. Established a Center for Vascular Research. 2. Establish Dr. March as Director of our Center. 3. Dr. March has more than 16 medical Patents 4. The Closer is being used on 500,000 patients annually. 5. Several Patents deal with the delivery of medicine to a damaged area. 6. Attracting a World Class Research Team to our Center. 7. The Research Team has over 300 Peer reviewed scientific publications to their credit.

9 Our Medical Director Keith March, M.D., Ph.D.

10 Dr. Keith March, M.D., Ph.D. Born June 4, 1963 Five Children Indiana University Ph. D with Highest Distinction Indiana University School of Medicine M.D./Ph.D. with highest Distinction 1985 Post Doctoral: Indiana U. Medical Center Medical Article Author & Editorial

11 General Grand Council has donated over $1,534,000.00

12 World Class Researchers Our Center includes clinicians, biologists, physicists, chemists,engineers, and technology transfer support. The participants within the center are also interacting with a highly complementary ensemble of industrial partners forming an overall consortium, with boundaries extending beyond the center itself.

13 Our Participants Our key collaborators have been found at Indiana University, Methodist Research Institute, Indiana State University, Purdue University and Rose-Hulman Institute of Technology. These participants provide across-the-board applied research, technology and experimental design to support the basic science projects.

14 Research Medical Team Dr. Dongming Hou M.D., Ph.D. -People s Repub. of China; Post Doc Univ. of Heidelberg,Germany Asst. Scientist IU Investigating the mechanism of restenosis and examining techniques to prevent it.

15 Research Medical Team Dr. Dan Meldrum M. D. Michigan State Residency, Univ. of Colorado; Fellowship, Johns Hopkins University Asst. Prof. of Surgery at Indiana University.

16 Dr. Dan Meldrum s Research Investigating the mechanism of how the heart produces cell damaging cytokines (agents) during heart attacks or heart surgeries and targeting therapies to determine if blocking cytokines such as tumor necrosis factor (TNF) aids the heart. Dr. Meldrum has authored over 100 peer reviewed scientific publications.

17 Research Medical Team Dr. Jalees Rehman

18 Dr. Jalees Rehman M.D. Munich, Germany; Post Doc. At Univ. of Calif.; Residency at IU Internal Med.; Cardiology Fellow, IU Investigating the role of stem cells and progenitor cells in cardiovascular disease. Also studying growth factors secreted by fat tissue to investigate the relationship between obesity and heart disease.

19 Research Medical Team Dongni Feng, Research Technician Studying molecular mechanisms directing artery remodeling NanKai University, People s Republic of China

20 Research Medical Team Catharine Williams, Lab. Tech. Animal Science, Purdue University Cell isolation to differentiate cultured cells General Laboratory support and cell culture experiments.

21 Dr March consults with Emily Judy an IU student learning about vascular research.

22 What are our current projects? I am looking at ways for people to grow new blood vessels (angiogenesis) using special delivery methods for genes and even using one s own cells to convey the genes. I like to think that researchers today are working to develop the medicine for tomorrow. Dr. March

23 CMMRF Director s Projects: 1. The Closer 2. Stimulating vessel growth around the heart. 3. Extensive research investigating the role of a variety of genes and cells and how they interact in vascular biology. 4. Implement clinical programs to provide excellent care to patients with all vascular diseases.

24 The Closer A Completed successful Cryptic Masons Director s Medical Project

25 ICVBM Project #1 The Closer

26 The Vascular Closer Patent in place and completed Produced by Abbott Vascular 500,000 sold in 2001 Increased production in the future Royalties returned to CMMRF Medical Center at Indiana University (IVCBM).

27 ICVBM Project #2 Recently ICVBM investigators have been experimenting with a groundbreaking technique to extract a special population of a patient s own cells from the fat tissue using liposuction. We have found that we can select cells that are like stem cells and may soon be able to re-introduce them into the patient s heart to enhance the growth of new blood vessels and possibly regenerate heart tissue.

28 ICVBM Project #3 Electronic Pulsation Device Non-Invasive device that uses electronic pulses to stimulate cell growth that produces a natural bypass around trouble areas in the coronary arteries.

29 Why is our research so important? Due to the length of time involved in developing a device like the Closer, it is necessary to think way ahead and advance research solutions to hasten clinical applications. To shorten this process, research dollars are critical. The more parallel efforts in place, the quicker solutions are found. Dr. March

30 Maintaining open arteries after Angioplasty One novel approach being developed and tested in the ICVBM involves the use of devices emitting ultrasound energy inside arteries following stenting to help perform gene therapy and keep such vessels open.

31 Early diagnosis of Coronary Artery Disease Your ICVBM investigators are developing techniques that will detect early abnormalities in the blood vessels by imaging inflamed areas of blood vessels entirely non-invasively.

32 Our Cryptic Mason Goals 1. Continued monetary support of the ICVBM. 2. $10,000,000 Foundation corpus for continued funding of future research. 3. Your commitment/pledge today will ensure our future success.

33 Cryptic Masons Medical Research Foundation What We Have Done For Ourselves Alone Dies With US; What We Have Done For Others And The World Is Immortal Albert Pike

34 General Grand Council, Cryptic Masons, International