Laboratory Animal Science - Main focus: Neuroscience

Transcription

1 Sarah Kimmina Klaus Nebendahl Laboratory Animal Science - Main focus: Neuroscience Proceedings of the 41th Annual Symposium of the Society for Laboratory Animal Science (GV-SOLAS) Göttingen Universitätsverlag Göttingen

2 2006 Universitätsverlag Göttingen ("

3 Magnetic Resonance Imaging of Animal Brain In Vivo 1 Jens Frahm, Oliver Natt, Takashi Watanabe, Susann Boretius, Thomas Michaelis Relevance of small animal models for TSE Research 15 IVJ. Schulz-Schaeffer Animal models for multiple sclerosis 19 C. Stade/mann Treatment trials for stroke: Preclinical and clinical models 34 Anna-Leena Siren and Hannelore Ehrenreich Non-Invasive Quantification of Brain Edema and the Space-Occupying effect in a permanent rat stroke model using magnetic resonance imaging 43 M. Walberer, T. Gerriets, E. Stolz, M. Kaps, C. Müller, A. Kluge, A. Bachmann, M. Fisher, M. Kaps, G. Bachmann Chronic rat models of cerebral oligaemia 47 Konstanze Plaschke, Hubert'. Bardenheuer, Eike Martin, Michael Knauth Hypothalamic injury and Hyperthermia (side effects of the suture model for MCA occlusion) can confound the evaluation of neuroprotective drugs 51 Al. Wa/berer, T. Gerriets, E. Stolz, M. Kaps, M. Fisher, G. Bachmann Superselective diagnostic and interventional angiography in rats Knauth, A. Mohr, K. Plaschke Intracoronary transplantation of autologous mesenchymal stem cells in a swine ischernic heart model 62 K. Guars, V. Zyba, T. Becker, S. Won, D. Lages, A.B. Buchwald, G. Hasenfuß Hepatocvte transplantation model and induction of intrahepatic stem cells 64 Sarah König, Petra Krause Recombination analysis in porcine endogenous retroviruses 68 B. /ligner, N. Klymiuk, M. Müller, G. Brem

4 Investigation of the efficacy of rodent microbiological monitoring methods in a ventilated cage rack system 72 Susan R Compton, Felix Homberger, Judy MacArthur Clark, Frank X Paturo. Optimization of the detection of Helicobacter spp. using PCR 74 K Jacobsen, E. Mahabir, M. Brielmeier, P. Wilhelm, K Seidel, J. Schmidt In utero infection of pseudopregnant mice recipients with Mouse Hepatitis Virus and Mouse Minute Virus 76 E. Mahabir, A. Mayer, J. Needham 1, J. Schmidt Health monitoring of laboratory rodents: incidence and relevance of bacterial isolates from the trachea 78 M. Brielmeier, P. Wilhelm andj. Schmidt Changes in differential haemogram after infusion of mean and low molecular weight hydroxyethyl starch (HES) in rats 81 M. Wagenblast, A. Theisen, Ch. Tandi, H. Forester Does inhalation anesthesia act beneficial in preventing distress from tail biopsy in laboratory mice? 85 M. An-as, A. Rettich, B. Seifert, T. Rülicke Animal Experimentation: A Comparison of the Attitude of the German and the British Population 87 C. Exner and G. Heldmaier WOKW rats: an excellent animal model for the complete metabolic syndrome 91 Ingrid Klöting and Nora Klöting The proinflammatory cytokine interferon-y induces chronic active myocarditis and cardiomyopathy in transgenic mice 96 S. Ott, J. Löhler, K Yamamur and K Reifenberg Genetics of the Metabolic Syndrome in NZO Mice 99 R. Kluge, M. Grothe, S. Scherneck, K. Schmor K Giesen, L Plum, H.G. Joost Differences of pathogenicity of Pasteurella pneumotropica biotypes 105 H. Meyer, S. Ott Health monitoring results obtained from mice and rats from commercial breeders 108 Werner Nicklas

5 The sheep as a chronic animal model for the long-term test of left ventricular assist device 112 C Ballat, H. Alekuzei, K Steinke, J. Schmitto, H. Doerge, F Schoendube Reconstitution of immunodeficient mice 114 Beuter, C., Stauffer, U., Kwiatkowski, H., Joswig, N., Mossmann, H. 4 Major candidate genes for experimental IBD identified by rnicroarray analysis in combination with quantitative trait locus (CTL) mapping data in mice 115 Andre Bleich, Jörg Lauber, Jan Buer, Hans Hedrich, Michael Mähler Health problems in South African Clawed Frogs (Xenopus laevis): Pathological, microbiological, and parasitological findings 117 Ines Bolle, Gem Hilken The influence of changed cage structuring on fighting and basic physiological parameters of the Athymic Nude-nu/nu mouse 119 T. Bürge, L Fozard Geneticalcharacterization of the LEW/Ztm-ci2 (circling2) and thebh.7a/ztmci3 (circling3) rats as animal models for syndromic deafness(ush1) respectively lateralization of brain function and hyperlocomotion 128 W. T. Chwalis D. Wedekind, H.J. Hedrich Induced Intracerebral Haemorrhage in Rats: Compparision of the Validity of Computertomography (CT) and Magnetresonanztomographie (MRI) 131 V. Elsie PyRAT- Python based relational animal tracking - a new web-based solution for animal facility management 135 J. Helppi, J. Oegema, J. Dupemn The dorsal skinfold chamber as useful model for the investigation of microcirculation and angiogenesis 136 Markus Heuser, Gerhard Zöller, Rolf H. Ringer', Bernhard Hemmerlein

6 Spontaneous tumours in a colony of Cynomolgus monkeys (Macaca fascicularis) observed during a 10-year period ( ), with a survey of the literature 137 J.Kaspareit, S.Friderichs-Gromoll, E.Buse, G.Habermann and F. Vogel Mycobacterium marinum infection in Xenopus laevis - a case study 140 Sarah Kimmina Determination of circadian rhythm of body temperature in laboratory mice and rats by rectal probe 141 M. Klein 1, T. Tillmannl, P. P. Tsai, H. Hackbarth, C. Dasenbmck Subcutaneously implanted transponders/microchips - a new minimally invasive method of body temperature measurement? 143 M. Klein, T. Tillmann, P. P. Tsai, H. Hackbarth, C Dasenbrock The polydactyly luxate syndrome of the rat: Morphological and genetical findings 145 C. Kruger, D. Büttner, H. Böhme, K Militrer Detection of MHV and MMV in mice: Comparison of a viral plaque assay with the MAP-test and PCR 147 E. Mahabir, K Jacobsen, D. Peters, J. Needham, J. Schmidt Individually Ventilated Cages and Open Cages with or without environmental enrichment: a comparative study on body weight, major organs weight and blood parameters in Hsd:ICR(CD-1) mice 149 Gianpaolo Milite Investigations on the effect of inhalative formaldehyde exposure on the open field behavior in rats 150 K-U. Mörit F. A. Malek, J. Fanghänel TierBase: A program for computer-assisted management of an animal breeding and experimentation facility 151 P. Nielsen and H. Mossmann Neuropathological results in laboratory mice 153 S. Ott, H. Meyer, N. Gerstmayr, G. Spindler Pasteurella pneumotropica - Pathology of Virulent Biotypes 154 S. Ott, H. Meyer, J. Brodbeck, P. Nusser, G. Spindler

7 New mouse models derived from the Munich ENU mouse mutagenesis project for iron metabolism research 155 B. Rathkolb, M. Klempt, M. Mohr, D. Soewarto, S. Hoffmann, S. Wagner, M. Hrabe de Angelis, E. Wolf, B. Aigner Effects of soy-containing rat chow on estrogen receptive organs 157 G. Rimoldi, J. Chistoffel, D. Seidlova-Wuttke, W. Wuttke Enrichment in the housing of laboratory dogs 158 L Schmid, D. Döring-Schätrl, M. H. Erhard The Effect of Hyperventilation on Cognitive Performance, Motor Function and Lesion Volume After Controlled Cortical Impact in the Rat 160 E. Eberspächer, M. Blobner, S. Riff, K. Engelhard, B. Eckel, C. Werner Right ventricular pressure load in pigs 162 C.Sellin, H. Doerge, M. Coulibaly, C. Muehlfeld, C. Ballatl, F.A. Schoendube Increased cancer risk in the B6C3F1 progeny of female mice exposed to X-rays before conception? 164 T. Tillmann, H. Ernst, C Dasenbrock EEG monitoring of anaesthetic depth using Bispectral Index (BIS T' ) measurement in large experimental surgery in swine 166 M. Wagenblast, H. Winklmaier and A. Theisen Changes in differential haemogram after infusion of mean and low molecular weight hydroxyethyl starch (HES) in rats 171 Al. Wagenblast, A. Theisen, Ch. Tandi, H. Forester Middle cerebral artery occlusion during MR-imaging (in-bore occlusion) -A new stroke model in rats 175 M. Walberer, T. Gerriets, E. Sto1, C Müller, A. Kluge, A. Bachmann, M. Kaps, G. Bachmann Cryopreservation of transgenic mouse embryos 178 K. Wayss, M. Klefen.z l J. Schenkel Understanding and Controlling for Background Strain Effects on Phenotype 179 C Cutler Linder, B. Witham