2009 Planning Calendar. January 15. February 1. January 1. February 15 MEETING DISTRIBUTION AND BONUS CIRCULATION

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1 January 1 Reservation: 12/2/08 Materials: 12/9/08 Special Display Advertiser Bonus Inclusion in exclusive online Biotrends 2009 article January 15 Reservation: 12/16/08 Materials: 12/23/08 Special opportunity for advertisers in this issue: Inclusion in GEN s Guess the Brand Challenge High-Content Analysis Protein Profiling Stem Cells Peptide Manufacturing Microarrays: DNA Arrays High-Throughput Automated Tools for Drug Discovery Microfluidics Cancer Biomarkers PCR and Molecular Diagnostics Culture Media for Bioprocessing High-Content Analysis, January 6-9, San Francisco Angiogenesis and Lymphangiogenesis in Cancer, January 6-11, Big Sky, MT Peptalk: The Protein Information Week, January 11-16, San Diego Mobilizing Cellular Immunity for Cancer Therapy, January 11-16, Snowbird, UT Stem Cells World Congress, January 20-22, Palm Springs, CA Bonus Circulation: Proteomics Researchers Miami Winter Symposium 2009: Interpreting the Human Genome, January 24-28, Miami Emerging Tumor Suppressors, January 25-30, Taos, NM LabAutomation 2009, January 25-28, Palm Springs, CA Omics Meets Cell Biology, January 25-30, Breckenridge, CO Drug Discovery Latin America, February 26-27, Rio de Janeiro, Brazil Biomanufacturing Summit 2009, January 27-28, San Diego Translational Cancer Medicine, January 27-28, San Diego Biomarker Assay Development, January 26-28, San Diego Biomarkers Summit 2009, February 2-3, London ABRF 2009, February 7-10, Memphis, TN Therapeutic Modulation of RNA Using Oligonucleotides, February 8-13, Lake Louise, Canada Access India & China, February 9-10, San Diego February 1 Reservation: 1/6/09 Materials: 1/9/09 February 15 Reservation: 1/16/09 Materials: 1/23/09 RNAi Protein Expression Analysis Epigenomics In vivo Imaging Post-Translational Modification Forensics Wall Street Roundup Web Exclusive Targeted Resequencing Pathway Analysis Trends in LC/MS Advances in Low-Volume Liquid Handling Monoclonal Antibody Production Bonus Circulation: Cancer Researchers AAAS Annual Meeting, February 12-16, Chicago ADMET Europe, February 23-25, Berlin Screening Europe 2009, February 23-25, Berlin AsiaTIDES, February 23-25, Tokyo Bonus Circulation: Forensic Scientists Molecular Medicine Tri-Conference, February 24-27, San Francisco Regulatory T Cells, March 1-6, Keystone, CO Genome Instability and DNA Repair, March 1-6, Taos, NM Process Validation for Biologicals, March 2-3, Carlsbad, CA Technology Transfer for Biopharmaceuticals, March 02-03, Carlsbad, CA Outsourcing Manufacturing of Biopharmaceuticals, March 02-03, Carlsbad, CA Antibody Development and Production, March 4-6, Carlsbad, CA Epigenetic Basis of Neurodevelopmental Disorders, March 6-10, Keystone, CO PITTCON 2009, March 8-13, Chicago GPCRS, March 3-4, Barcelona Bonus Circulation: HPLC Users For updated information, check

2 March 1 Reservation: 2/05/09 Materials: 2/11/09 Message Impact Study RNA Sample Prep SNP vs. Copy Number Variation SPR/Protein Interactions Disposables for Bioprocessing Biomarker Assay Development Contract Production qpcr 2009, March 9 13, Freising, Germany Quantitative PCR, March 16-17, San Diego Biomedical Asia 2009, March 16-19, Suntec, Singapore Bio-Europe Spring, March 16-18, Milan Interphex 2009, March 17-19, New York Next-Generation Sequencing, March 18-19, San Diego Cell Death Pathways, March 22-27, Whistler, Canada Targeting Metabolic Disorders, March 23-24, Boston China 2009 Pharmaceutical R&D Summit, April 1-3, Shanghai PEPCON, April 2-4, Seoul, Korea IBIO, April 5-7, Seoul, Korea Bonus Circulation: DNA Sequencing Core Facility Scientists March 15 Reservation: 2/13/09 Materials: 2/20/09 microrna Profiling Microarrays: Protein Arrays Small Molecule Drug Discovery Label-Free Screening Contract Research Biofuel Production microrna in Human Disease and Development, March 23-26, Boston Antibodies as Drugs, March 27-April 1, Whistler, Canada Targeted Cancer Therapeutics, March 27-April 1, Whistler, Canada OPT: Oligonucleotide & Peptides as Therapeutics 2009, April 1-2, Waltham, MA RNA Interference 2009, April 1-2, Waltham, The Future of Biofuels, April 4-8, Snowbird, UT Drug Discovery Chemistry, April 6-8, San Diego PEGS (Protein Engineering Summit), April 6-10, Boston Advances in Synthetic Chemistry, April 16-17, Edinburgh, Scotland Experimental Biology, April 18-22, New Orleans World Vaccine Congress Washington 2009, April 20-23, Washington, DC CISILE 2009, April 9-11, China April 1 Reservation: 3/6/09 Materials: 3/13/09 Cancer Molecular Diagnostics qpcr Detection Digital Gene Expression Metabolomics Cellular Bioenergetics Green Biomanufacturing Bonus Circulation: microrna Researchers Biological Assay Development & Validation, April 14-16, Washington, DC AACR 100th Annual Meeting, April 18-22, Denver PABME 2009, April 20-22, Dubai BioProcess International 2009, April 22-23, Dusseldorf, Germany Stem Cell Niche Interactions, April 21-26, Whistler, Canada PI 3-Kinase Signaling in Disease, April 22-27, Lake Tahoe, CA Advances in Synthetic Biology, April 28-29, London April 15 Reservation: 3/19/09 Materials: 3/26/09 Nucleic Acid Sample Prep Cell-Based Assays DNA Sequence Analysis HTS: Turning Hits into Leads Downstream Bioprocess Bottlenecks Bonus Circulation: Biomarker Researchers The Biology of RNA Silencing, April 25-30, Victoria, Canada BIO-IT World Conference & Expo, April 27-29, Boston 10th Annual Immunogencity for Biotherapeutics, May 4-6, San Diego, CA Vaccine Development Forum, May 6-8, Boston, MA ACHEMA 2009, May 11-15, Frankfurt, Germany DxRx Summit: Nucleic Acid Diagnostics & Therapeutics, May 12-13, Boston Bonus Circulation: Bioprocess Engineers For updated information, check

3 May 1 Reservation: 4/7/09 Materials: 4/14/09 May 15 Reservation: 4/20/09 Materials: 4/27/09 June 1 Reservation: 5/5/09 Materials: 5/12/09 June 15 Reservation: 5/20/09 Materials: 5/27/09 July Reservation: 6/5/09 Materials: 6/12/09 HPLC Update Protein Characterization ADME/Tox Kinase Assays Systems Biology Oligo Manufacturing Emerging Bioclusters Mass Spectrometry Drug Delivery Microarrays: CGH and Diagnostics Cell Signaling Virus Removal in Bioproduction RNAi Therapeutics Single-Cell Genomics Ion Channels Microarray Data Analysis Protein Production Biomarker Validation Multiplexing Protein Engineering Bioprocess Cell Line Optimization Contract Manufacturing Biomagnetic Separations Real-Time PCR Transfection Review Peptide Synthesis Cell Viability Assays Downstream Processing Stem Cells & Regenerative Medicine 2009, May 11-12, Seattle, WA Cell Signaling & Assay Technologies 2009, May 11-12, Seattle, WA World Stem Cells & Regenerative Medicine Congress 2009, May 12-14, London RNAi World Congress May 14-15, Boston TIDES, May 17-20, Las Vegas 109th ASM General Meeting, May 17-20, Philadelphia BIO International Convention, May 18-21, Atlanta Lab-on-a-Chip European Congress, May 19-20, Stockholm Advances in Microarray Technology, May 19-20, Stockholm Molecular Diagnostics Europe, May 19-20, Stockholm Nucleic Acids Technologies for Diagnostics, May 19-20, Las Vegas Biomarker World Congress, May 27-29, Philadelphia Clinical Trials in China, May 29-30, Beijing Bonus Circulation: Assay Development Scientists American Society of Gene Therapy, May 27-31, San Diego ASMS Conference on Mass Spectrometry, May 31-June 4, Philadelphia Global Protein Summit, June 1-2, London Protein Kinase Targets, June 1-3, Cambridge MA Single-Use Applications for Biopharmaceutical Manufacturing, June 1-3, San Diego Drug Discovery & Development of Innovative Therapeutics Japan, June 1-3, Tokyo Biotech China, June 1-3, Shanghai Structure-Based Drug Design, June 4-5, Cambridge, MA ESACT 2009, June 7-10, Dublin World Pharmaceutical Congress, June 8-11, Philadelphia Cancer Proteomics, June 8-11, Dublin World Vaccine Congress Asia, June 8-11, Singapore RNAi, sirna & mirna, June 10-11, London World Congress of Cancer, June 19-22, Beijing Bonus Circulation: Molecular Diagnostic Researchers Drug Discovery: Easing the Chemistry Bottleneck, June 8-9, Philadelphia RNAi for Target Identification, June 9-10, San Francisco MicroRNA and Cancer, June 10-15, Keystone, CO CALAsia, June 14-16, San Diego qpcr-quantitive Polymerase Chain Reaction & Transcriptional Profiling June 15-16, London Bangalore BIO, June 18-20, Bangalore HPLC 2009, June 28 - July 2, Dresden, Germany BioPharm Asia 2009, June 29-30, Singapore AgriGenomics World Congress, July 2-3, London Bonus Circulation: Microarray Users CHIRALITY 2009, July 12-15, Breckenridge, CO SNiPomics 2009, July 13-14, Boston Epigenomics & Sequencing 2009, July 13-14, Boston ISMB 2009, June 27-July 2, Sweden ADMET, July 1-2, London International Bio Forum & Bio Expo Japan, July 1-3, Tokyo ISSCR 7th Annual Meeting, July 8-11, Barcelona Charles Darwin Conference, July 9-11, Pathumthani, Thailand World Summit of Antivirals, July 18-25, Beijing Bonus Circulation: Methods Development Scientists PREP 2009, July 19-22, Philadelphia Society for Industrial Microbiology, July 26-30, Toronto Bonus Circulation: Gene Silencing Researchers For updated information, check

4 August Reservation: 7/8/09 Materials: 7/15/09 Biomarkers in Drug Discovery Microarrays: Gene Expression Novel Assay Development Bioreactors and Fermentors Monoclonal Antibody Production Bioprocess Scale-Up Drug Discovery & Development of Innovative Therapeutics,Aug 3-6, Boston Lab on-a-chip, August 6-7, San Francisco Molecular Diagnostics World Congress, August 6-7, San Francisco Microarray World Congress, August 6-7, San Francisco ELRIG Drug Discovery 2009, September 7-8, Liverpool, UK CELLutions SUMMIT, August 11-13, Cambridge, MA ACS Fall National Meeting, August 16-20, Washington, DC Pharmaceutical Regulatory Affairs, August 24-25, Singapore BioProcess International China, September 7-9, Beijing China PDA/FDA Joint Regulatory Conference, September 14-18, Washington DC Bonus Circulation: Bioprocess Engineers September 1 Reservation: 8/4/09 Materials: 8/11/09 Message Impact Study Protein Sample Prep Next-Generation Sequencing Molecular Diagnostics Live Cell Imaging Bioprocess Monitoring and Control Peptide Drug Discovery RNAi Europe 2009, September 17-18, Berlin Advances in qpcr 2009, September 17-18, Berlin Epigenomics World Congress 2009, September 17-18, Berlin Peptides Europe, September 17-18, Berlin Beyond Antibodies, September 21-23, San Diego Biological Production 2009, September 21-22, London Next-Generation Sequencing Data Analysis, September 21-23, Providence, RI Exploring Next-Generation Sequencing, September 21-23, Providence, RI Biorepositories 2009, September 21-23, Philadelphia, PA Flow Cytometry, September 22-23, Boston, MA High-Content Data Analysis, September 22-23, Boston, MA Live-Cell Imaging, September 22-23, Boston, MA Clinical Biomarkers, September 22-24, Washington, DC Personalized Medicine, September 22-24, Washington DC Translational Cancer Medicine, September 22-24, Washington, DC Biomarker Data Analysis, September 22-24, Washington, DC ADAPT 2009, September 22-25, Washington, DC Biomarkers in Clinical Trials, September 23-24, London, UK Biologics Drug Delivery & Beyond, September 23-25, Boston MA Vaccine Development Forum, September 23-25, Boston, MA ABIC 2009, Sept 23-25, Bangkok, Thailand Stem Cells Europe 2009, September 23-25, Edinburgh, Scotland PharmaTrials Asia, September 23-25, Shanghai, China. Protein Biomarkers, September 24-25, Washington DC World Biobanking Summit, September 24-25, Edinburgh, Scotland Generics Asia Summit 2009, September 29-30, Singapore Bonus Circulation: Cell Biologists September 15 Reservation: 8/18/09 Materials: 8/25/09 3-D Cell Culture microrna Analysis Metabolite Profiling Protein Therapeutic Formulation Vaccine Production Bioanalytical Method Development, October 5-7, Berkeley,CA 5th Annual Cell Based Assays, October 5-7, Berkeley CA Biotechnica 2009, October 6-8, Hannover, Germany World Vaccine Congress, October 6-9, Lyon, France 4th Annual Frontiers of Clinical Investigation, October 8-10, La Jolla CA CPhI Worldwide 2009, October 13-15, Madrid Bonus Circulation: Metabolomics Researchers For updated information, check

5 October 1 Reservation: 9/3/09 Materials: 9/10/09 Protein Quantitation Automated Sample Prep Biomarker Assays Protein Expression Challenges Contract Manufacturing BioProcess International Conference & Exhibition, Oct 12-16, Raleigh, NC Drug Repositioning Summit, October 13-14, Boston, MA Formulation Strategies for Biopharmaceuticals, Oct 13-15, Raleigh, NC MipTec 2009, Oct 13-15, Basel, Switzerland Society for Neuroscience, October 17-21, Chicago IDDST, October 22-25, Shanghai, China BioProduction 2009, October 27-28, Barcelona Stem Cells & Regenerative Medicines Asia, October 27-29, Singapore Targeting Diabetes with Novel Therapeutics, October 22-23, Boston Bonus Circulation: Proteomics Researchers October 15 Reservation: 9/17/09 Materials: 9/24/09 qpcr Analysis Advances in Microarray Processing/Production Stem Cells Image Analysis Novel Cell Culture Techniques American Society of Human Genetics, October 20-24, Honolulu Drug Discovery Partnership: Academia & Industrial Interactions, Oct 28-30, Boston MicroRNAs Europe 2009, Nov 2-3, Cambridge, UK RNAi for Screening, November 2-3, Boston, MA HDAC Inhibitors, November 2-3, Boston, MA Ion Channels as Therapeutic Targets, November 2-3, Boston, MA G-Protein Coupled Receptors, November 2-3, Boston, MA Discovery On Target, November 2-4, Boston Preclinical Scale Bioprocessing, November 2-4, Boston Bio-Europe 2009, November 2-4, Vienna RNAi for Therapeutics, November 3-4, Boston, MA Kinase Inhibitors, November 3-4, Boston, MA EpiStem 2009: European Epigenomics & Stem Cells, Nov 4-5, Cambridge, UK European Biomarkers Summit, November 5-6, Barcelona Advances in Metabolic Profiling, November 5-6, Barcelona Mass Spec Europe, November 5-6, Barcelona qpcr Symposium USA, November 9-12, San Francisco Bay Area Well-Characterized Biologicals, Nov, Nov 10-12, Reston, VA Bonus Circulation: Stem Cell Researchers November 1 Reservation: 10/1/09 Materials: 10/8/09 Updates in Biodefense Technologies Whole Animal Imaging Small Molecule Drug Discovery Mass Spec Sample Prep Single-Use vs. Reusable Bioprocessing Clinical Trails Summit, Nov 11-12, Singapore The Science of Biobanking, Nov 16-17, Philadelphia Advances in Gene Expression Profiling, Nov 17-18, Philadelphia European Antibody Congress 2009, Nov 30 Dec 2, Geneva, Switzerland Bonus Circulation: Mass Spectroscopists For updated information, check

6 November 15 Reservation: 10/20/09 Materials: 10/27/09 Cell Signaling Transfection Update Multiplexing Flow Cytometry Advances in RT-PCR Bioproduct Stability Testing biologic India, December 1-3, India 3rd World Congress of Gene 2009, Dec 1-7, Foshan China World Congress of Omics, December 1-7, China EuroTides 2009, December 2-3, Amsterdam, Netherlands American Society for Cell Biology December 5-9, San Diego Frontiers in Synthetic Biology 2009, Dec 7-8, Burlingame, CA Biofuels & Green Chemistry 2009, Dec 7-8, Burlingame, CA Antibody Engineering, December, TBA Antibody Therapeutics, December, TBA Bonus Circulation: Bioprocess Engineers December Reservation: 11/3/09 Materials: 11/10/09 sirna Synthetic Biology Bioprocess Filtration microrna and Cancer Contract Research 8th Annual Partnering with Central Labs, ECG, & Imaging Labs, January 26-28, Las Vegas Bonus Circulation: RNAi Researchers 140 Huguenot St., 3rd Floor New Rochelle, NY tel: (914) fax: (914) Group Publisher Joan Boyce tel: (914) Senior Vice President Global Sales & Marketing Asia Display and Classified & Marketplace Harriet I. Matysko tel: (914) East Coast Sales Manager Monica Lieberman tel: (914) fax: (914) Midwest Sales Manager Sharon Spitz tel: (888) ADS-4-GEN ( ) fax: (914) West Coast Sales Manager Mary Tonon tel: (415) fax: (415) Europe & Australia Display and Classified & Marketplace Hilary Turnbull tel: +44 (0) fax: +44 (0) North America Classified & Marketplace Sales Manager Victoria Palusevic tel: (914) Director of Advertising Production Anne B. Chin Aleong tel: (914)