Contents PART 1 EXPERT INTERVIEW WITH BRUCE TOMPKIN PART 2 PATHOGEN UPDATES
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1 Contents PART 1 EXPERT INTERVIEW WITH BRUCE TOMPKIN Interview with a food safety expert: Dr R. Bruce Tompkin R B Tompkin, Retired, USA and J Sofos, Colorado State University, USA - Food safety: past and current - Food safety management systems - Future efforts to further control food safety concerns PART 2 PATHOGEN UPDATES Pathogen update: Salmonella T Hald, DTU, Denmark - Incidence and burden of human salmonellosis - Epidemiology and disease transmission in humans - Classification and subtypes - Tracing the sources of human salmonellosis source attribution - Discussion on sources to human salmonellosis Pathogen update: Listeria monocytogenes J Chen and K Nightingale, Texas Tech, USA - The genus Listeria, L monocytogenes and listeriosis - Listeriosis: epidemiology, virulence factors and evolution - In vitro and in vivo models to assess virulence - Ecology, transmission and genetic diversity of L Monocytogenes - Regulations and risk assessments s Pathogen update: Bacillus species F Carlin, INRA, France and C Nguyen-the, INRA, France - Bacillus cereus in food: characterisation and taxonomy - Poisoning caused by B cereus and other Bacillus spp - Control of Bacillus species in foods and food processing Pathogen update: Vibro species M Strom, National Oceanic and Atmospheric Administration, USA - Source of infection, types of pathology - Virulence and strain variability - Current risk management Other human food-borne pathogenic vibrios - Current and future trends Emerging parasites in food Y Ortega, University of Georgia, USA - Protozoa - Cestoda - Nematoda - Trematoda - Epidemiology, prevention and control
2 s New research on antimicrobial resistance in foodborne pathogens J Threlfall, HPA, UK - Increasing occurrence of resistance to quinolones and cephalosporins in Salmonella - Increasing occurrences of resistance to quinolones and macrolides in Campylobacter - The recent emergence and spread of new multidrug-resistant clones of monophasic Salmonella Typhimurium-like organisms - Rapid emergence and spread of strains of Enterobacteriaceae, and in particular Escherichia coli, exhibiting resistance to extended spectrum beta (ß)-lactamases (ESBLs) or producing AmpC (ß)- lactamases, control measures Antibiotic resistance development and identification of response measures T Kuile and S Brul, University of Amsterdam, The Netherlands - Existing international risk assessments - Control targets - Monitoring and reporting usage and resistance - Reservation of antibiotics for human health care - Prudent use - Role of the competent authorities - Responsibilites for veterinarians - Farmers mission - Control measures that can be implemented immediately PART 3 PATHOGEN SURVEILLANCE, DETECTION AND IDENTIFICATION Advances in separation and concentration of microorganisms from food samples L Jaykus and S H Suh, North Carolina State University and Byron Brehm-Stecher, Iowa State University, USA - The need for pre-analytical sample processing - Emerging approaches s Second generation polymerase chain reaction (PCR) and DNA microarrays for in vitro and in situ study of foodborne pathogens K Rantsiou and L Cocolin, University of Turin, Italy - Quantitative polymerase chain reaction (PCR) - Transcriptomics s and future trends New approaches in microbial pathogen detection J Irudayaraj, Purdue University, USA - Detection methods - Emerging methods
3 Tracking of pathogens via virulence factors: Shiga toxin-producing Escherichia coli in cattle and potential risk for human disease J Elder, Colorado State University and K Nightingale, Texas Tech, USA - The impact of Shiga toxin-producing E.coli (SHEC) on public health - STEC virulence factors - Prevalence of STEC in cattle and other reservoirs - Challenges and considerations for the detection of STEC - Summary and discussion and further readings New research on estimating the global burden of foodborne disease R Lake, Institute of Environmental Science and Research, New Zealand, A H Havelaar, National Institute for Public Health and the Environment, The Netherlands and T Kuchenmuller, WMO, Denmark - Estimating the burden of foodborne diseases: metrics and attribution - Foodborne Disease Burden Epidemiology Reference Group (FERG) structure and process - FERG outputs to date and additional reading PART 4 FOOD PRESERVATION TECHNIQUES Novel methods for pathogen control in livestock preharvest: an update T R Callaway, R C Anderson, T S Edrington, K J Genovese, R B Harvey, T L Poole and D J Nisbet, USDA-ARS, USA - Foodborne pathogenic bacteria: Human exposure routes - The gastrointestinal tract microflora and ecological inertia - Delineation of anti-pathogen versus pro-commensal strategies - Competitive enhancement strategies to reduce food-borne pathogens - Direct anti-pathogen strategies to reduce food-borne pathogen - Animal management intervention strategies s New research on ensuring safety in dry processing environments J-L Cordier, Nestlé Quality Assurance Center, Switzerland - Control measures applied during the manufacture of low-moisture products - Survival of pathogens low-moisture products and environments - Fate of pathogens low-moisture processing environments - Cleaning procedures - Verification of control measures - Disinfection and use of sanitizers New research on bacteriophage and food safety J Klumpp and M J Loessner, ETH Zurich, Switzerland - Bacteriophages of foodborne pathogens - General considerations for bacteriophage application - Phage preparations for pathogen detection and control - Bacteriophage lytic enzymes and their application in food - Pathogen detection
4 s New research on MAP and pathogen behaviour A Vermeulen, P Ragaert, A Rajkovic, S Samapundo, F Lopez-Galvez and F Devlieghere, Ghent University, Belgium - Trends in packaging configurations - Effect of packaging configuration on food safety - Critical evaluation of current research on modified atmosphere packaging and food safety and some future research trends New research on organic acids and pathogen behaviour K Koutsoumanis, Aristotle University of Thessaloniki and P Skandamis, Agricultural University of Athens, Greece - Applications of organic acids in fresh meat decontamination - Application of organic acids in fresh produce decontamination - Risks and concerns: microbial adaptation - Legislation aspects and further reading Progress in intervention programmes to eradicate foodborne helminth infections K Kniel, University of Delaware, USA - Foodborne helminth infections and food animal contamination - Impact of intervention programs - Future directions PART 5 PATHOGEN CONTROL MANAGEMENT Advances in understanding of the impact of personal hygiene and human behaviour on food safety C Griffith, Editor of British Food Journal, UK - Food handler knowledge and practices - Food handlers, cross contamination and hand hygiene - Food safety culture - Food hygiene training and future trends - Further reading Expanding the use of HACCP beyond its traditional application areas W H Sperber, Retired, USA - Historical perspective - Contemporary perspective - Expansion of HACCP beyond traditional areas of application - Necessary and practical food safety improvements - Barriers to food safety progress - A plan for global food safety progress
5 Biotracing in food safety G C Barker, Institute of Food Research, UK - Elements of biotracing - Biotracing in food chain systems PART 6 UNDERSTANDING AND MODELLING PATHOGEN BEHAVIOUR Advances in single-cell approaches for the study of foodborne pathogens B Brehm-Stecher, Iowa State University, USA - Single-cell analyses in food microbiology - Advances in single-cell techniques for the study of foodborne pathogens and future trends Advances in genomics and proteomics-based methods for the study of foodborne bacterial pathogens P Fratamico, USDA-ARS, USA - Genomic technologies: sequencing, typing and profiling - Functional genomics - Molecular serotyping, subtyping and metagenomics - Food-based proteomic investigations (including introductory section Proteomic-based techniques ) - Mass spectrometry Next generation of predictive models J Baranyi, A Metris and C Pin, Institute of Food Research, UK - Models at cell-population level - Models at single-cell level - Molecular level s
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