NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY DEPARTMENT OF BIOTECHNOLOGY Professor Bjørn E. Christensen, Department of Biotechnology
|
|
- Mildred Eleanore McCoy
- 5 years ago
- Views:
Transcription
1 Page 1 NRWEGIAN UNIVERSITY F SCIENCE AND TECNLGY DEPARTMENT F BITECNLGY Professor Bjørn E. Christensen, Department of Biotechnology Contact during the exam: phone: , EXAM TBT4135 BIPLYMERS 16 December 2010 Time: Aides: B1. Approved calculator with empty memory, according to list provided by NTNU, is permitted. No printed or written documents may be used during exam. Censoring deadline: 16 January 2011 Censoring: Relative weights of questions: See Appendix 2
2 Page 2 Question 1. a) Describe the chemical structure of cellulose (including aworth formulae) b) Explain briefly the concept ʻdiequatorialʼ linkages c) Which glycosidic linkages in cellulose are diequatorial? d) Explain briefly the chemical basis for production of carboxymethyl cellulose (CMC) (reactants, conditions, mechanism)? e) Cellulose and CMC have different physical properties. Which is the most important? f) The average pk a of CMC is 4.4, whereas the average pk a of a chitosan is 6.0. In which p range can chitosan and CMC in principle form a polyelectrolyte complex (oppositely charged polymers)? Brief explanation. Question 2. The data below shows of the radius of gyration (R G ) and the molecular weight (M w ) for three different biopolymers (A-C) in solution. The data refer to a p of 7.0, room temperature, and an ionic strength (I) of 0.1 M ! " # $ % &'(''' )*+& ),+' -+',''('''.,+' /)+0,/+* 0''(''','0+' 0&+* &)+' a) What is the shape of each of the biopolymers? b) Comment difference in R G -M data between B and C c) B is a polysaccharide containing sulphate groups (one sulphate per 2 sugars on average). ow would R G -M data change (qualitatively) if the
3 Page 3 values were determined at a higher ionic strength (e.g. in 1 M instead of 0.1 M)? d) Define the ionic strength (I) and calculate I for 0.1 M MgCl 2. e) B forms a thermoreversible gel in the presence of K + (potassium) ions. Which polysaccharide can it be? (Name) Question 3. Two proteins (A and B) are both biologically active at 37 C. They both contain several α-helices, which in each case are organised into a well-defined tertiary structure (not the same for A and B). Protein A looses activity upon heating, whereas B looses activity upon cooling. a) Describe briefly the main properties of α-helices in proteins b) What is the thermodynamic explanation for the behaviour of A and B, respectively? c) Can the differences in behaviour be explained in terms of the primary structure? Explain briefly. d) Analysis of the genes in an animal tissue revealed the amino acid sequence of the corresponding protein which given in Appendix 1. Which type of protein is it (most probably)? Brief explanation. e) Are there any ʻanalogiesʼ to the behaviour of protein B among the polysaccharides, for example related to solubility?
4 Page 4 Question 4. Identify the monosaccharides (a-c) and the polysaccharide (d). For monosaccharides, include also the D/L and the anomeric configuration (α/β): a) C b) c) C C 2 d) CNa N C C 3 n
5 Page 5 Question 5. a) Some alginates form strong, elastic gels when Ca ++ ions are added. Which types of alginates form the strongest gels, and what is the mechanism of gelation? b) Alginates can be degraded (depolymerized) by several mechanisms. Explain the chemical principles of one of the mechanisms. c) Assume a sodium (Na + ) alginate is randomly degraded from M w = to g/mol in 60 min. ow long time will it take to degrade from to g/mol? d) Estimate DP n of the alginate when M w is g/mol. e) What is the relative content (weight fraction) of alginate oligomers with DP = 10 in the reaction mixture when M w has reached g/mol?
6 Page 6 APPENDIX 1: Amino acid abbreviations: Amino acid Three letter code ne letter code alanine ala A arginine arg R asparagine asn N aspartic acid asp D asparagine or aspartic acid asx B cysteine cys C glutamic acid glu E glutamine gln Q glutamine or glutamic acid glx Z glycine gly G histidine his isoleucine ile I leucine leu L lysine lys K methionine met M phenylalanine phe F proline pro P serine ser S threonine thr T tryptophan try W tyrosine tyr Y valine val V
7 Page 7 Appendix 2 1a 4 1b 4 1c 3 1d 3 1e 3 1f 3 2a 12 2b 4 2b 4 2c 4 2e 3 3a 6 3b 4 3c 3 3d 3 3e 3 4a 3 4b 3 4c 3 4d 4 5a 4 5b 4 5c 6 5d 3 5e 4 Sum 100
11 questions for a total of 120 points
Your Name: BYS 201, Final Exam, May 3, 2010 11 questions for a total of 120 points 1. 25 points Take a close look at these tables of amino acids. Some of them are hydrophilic, some hydrophobic, some positive
More informationBasic concepts of molecular biology
Basic concepts of molecular biology Gabriella Trucco Email: gabriella.trucco@unimi.it Life The main actors in the chemistry of life are molecules called proteins nucleic acids Proteins: many different
More informationDNA.notebook March 08, DNA Overview
DNA Overview Deoxyribonucleic Acid, or DNA, must be able to do 2 things: 1) give instructions for building and maintaining cells. 2) be copied each time a cell divides. DNA is made of subunits called nucleotides
More informationProblem: The GC base pairs are more stable than AT base pairs. Why? 5. Triple-stranded DNA was first observed in 1957. Scientists later discovered that the formation of triplestranded DNA involves a type
More informationUsing DNA sequence, distinguish species in the same genus from one another.
Species Identification: Penguins 7. It s Not All Black and White! Name: Objective Using DNA sequence, distinguish species in the same genus from one another. Background In this activity, we will observe
More informationBasic concepts of molecular biology
Basic concepts of molecular biology Gabriella Trucco Email: gabriella.trucco@unimi.it What is life made of? 1665: Robert Hooke discovered that organisms are composed of individual compartments called cells
More information6-Foot Mini Toober Activity
Big Idea The interaction between the substrate and enzyme is highly specific. Even a slight change in shape of either the substrate or the enzyme may alter the efficient and selective ability of the enzyme
More informationGranby Transcription and Translation Services plc
ompany Resources ranby Transcription and Translation Services plc has invested heavily in the Protein Synthesis business. mongst the resources available to new recruits are: the latest cellphones which
More informationAlgorithms in Bioinformatics ONE Transcription Translation
Algorithms in Bioinformatics ONE Transcription Translation Sami Khuri Department of Computer Science San José State University sami.khuri@sjsu.edu Biology Review DNA RNA Proteins Central Dogma Transcription
More informationMaterials Protein synthesis kit. This kit consists of 24 amino acids, 24 transfer RNAs, four messenger RNAs and one ribosome (see below).
Protein Synthesis Instructions The purpose of today s lab is to: Understand how a cell manufactures proteins from amino acids, using information stored in the genetic code. Assemble models of four very
More informationProtein Structure and Function! Lecture 4: ph, pka and pi!
Protein Structure and Function! Lecture 4: ph, pka and pi! Definition of ph and pk a! ph is a measure of the concentration of H +.! + ph = log 10[H ] For a weak acid,! HA #!!"! H + + A!, K a = [H + ][A!
More informationProteins: Wide range of func2ons. Polypep2des. Amino Acid Monomers
Proteins: Wide range of func2ons Proteins coded in DNA account for more than 50% of the dry mass of most cells Protein func9ons structural support storage transport cellular communica9ons movement defense
More informationBioinformatics. ONE Introduction to Biology. Sami Khuri Department of Computer Science San José State University Biology/CS 123A Fall 2012
Bioinformatics ONE Introduction to Biology Sami Khuri Department of Computer Science San José State University Biology/CS 123A Fall 2012 Biology Review DNA RNA Proteins Central Dogma Transcription Translation
More informationProtein Structure Analysis
BINF 731 Protein Structure Analysis http://binf.gmu.edu/vaisman/binf731/ Secondary Structure: Computational Problems Secondary structure characterization Secondary structure assignment Secondary structure
More informationFundamentals of Protein Structure
Outline Fundamentals of Protein Structure Yu (Julie) Chen and Thomas Funkhouser Princeton University CS597A, Fall 2005 Protein structure Primary Secondary Tertiary Quaternary Forces and factors Levels
More informationProtein Synthesis. Application Based Questions
Protein Synthesis Application Based Questions MRNA Triplet Codons Note: Logic behind the single letter abbreviations can be found at: http://www.biology.arizona.edu/biochemistry/problem_sets/aa/dayhoff.html
More informationAdditional Case Study: Amino Acids and Evolution
Student Worksheet Additional Case Study: Amino Acids and Evolution Objectives To use biochemical data to determine evolutionary relationships. To test the hypothesis that living things that are morphologically
More informationNucleic acid and protein Flow of genetic information
Nucleic acid and protein Flow of genetic information References: Glick, BR and JJ Pasternak, 2003, Molecular Biotechnology: Principles and Applications of Recombinant DNA, ASM Press, Washington DC, pages.
More informationAipotu II: Biochemistry
Aipotu II: Biochemistry Introduction: The Biological Phenomenon Under Study In this lab, you will continue to explore the biological mechanisms behind the expression of flower color in a hypothetical plant.
More informationSteroids. Steroids. Proteins: Wide range of func6ons. lipids characterized by a carbon skeleton consis3ng of four fused rings
Steroids Steroids lipids characterized by a carbon skeleton consis3ng of four fused rings 3 six sided, and 1 five sided Cholesterol important steroid precursor component in animal cell membranes Although
More informationBiochemistry and Cell Biology
Biochemistry and Cell Biology Monomersare simple molecules that can be linked into chains. (Nucleotides, Amino acids, monosaccharides) Polymersare the long chains of monomers. (DNA, RNA, Cellulose, Protein,
More informationBi Lecture 3 Loss-of-function (Ch. 4A) Monday, April 8, 13
Bi190-2013 Lecture 3 Loss-of-function (Ch. 4A) Infer Gene activity from type of allele Loss-of-Function alleles are Gold Standard If organism deficient in gene A fails to accomplish process B, then gene
More information2) Which functional group is least important in biochemistry? A) amine B) ester C) hydroxyl D) aromatic E) amide
1) All of the following can be classified as biomolecules except A) lipids. B) proteins. C) carbohydrates. D) nucleic acids. E) All of the above are biomolecules. 2) Which functional group is least important
More informationMOLEBIO LAB #3: Electrophoretic Separation of Proteins
MOLEBIO LAB #3: Electrophoretic Separation of Proteins Introduction: Proteins occupy a central position in the structure and function of all living organisms. Some proteins serve as structural components
More informationHomework. A bit about the nature of the atoms of interest. Project. The role of electronega<vity
Homework Why cited articles are especially useful. citeulike science citation index When cutting and pasting less is more. Project Your protein: I will mail these out this weekend If you haven t gotten
More informationUnit 1. DNA and the Genome
Unit 1 DNA and the Genome Gene Expression Key Area 3 Vocabulary 1: Transcription Translation Phenotype RNA (mrna, trna, rrna) Codon Anticodon Ribosome RNA polymerase RNA splicing Introns Extrons Gene Expression
More informationTurning λ Cro into a
Turning λ Cro into a 3 Transcriptional Activator Figure by MIT pencourseware. Fred Bushman and Mark Ptashne Cell (1988) 54:191-197 Presented by atalie Kuldell for 0.90 February 4th, 009 Small patch of
More informationENZYMES AND METABOLIC PATHWAYS
ENZYMES AND METABOLIC PATHWAYS This document is licensed under the Attribution-NonCommercial-ShareAlike 2.5 Italy license, available at http://creativecommons.org/licenses/by-nc-sa/2.5/it/ 1. Enzymes build
More informationAOCS/SQT Amino Acid Round Robin Study
AOCS/SQT Amino Acid Round Robin Study J. V. Simpson and Y. Zhang National Corn-to-Ethanol Research Center Edwardsville, IL Richard Cantrill Technical Director AOCS, Urbana, IL Amy Johnson Soybean Quality
More informationBIOSTAT516 Statistical Methods in Genetic Epidemiology Autumn 2005 Handout1, prepared by Kathleen Kerr and Stephanie Monks
Rationale of Genetic Studies Some goals of genetic studies include: to identify the genetic causes of phenotypic variation develop genetic tests o benefits to individuals and to society are still uncertain
More informationYour Name. Mean ± SD = 72.3 ± 17.6 Range = out of 112 points N = Points
Introduction to Biochemistry Final Examination - Individual (Part I) Thursday, 24 May 2012 3:30 5:30 PM, 206 Brown Lab H. B. White Instructor Your Name Mean ± SD = 72.3 ± 17.6 Range = 23 99 out of 112
More informationFirst&year&tutorial&in&Chemical&Biology&(amino&acids,&peptide&and&proteins)&! 1.&!
First&year&tutorial&in&Chemical&Biology&(amino&acids,&peptide&and&proteins& 1.& a. b. c. d. e. 2.& a. b. c. d. e. f. & UsingtheCahn Ingold Prelogsystem,assignstereochemicaldescriptorstothe threeaminoacidsshownbelow.
More informationStructure formation and association of biomolecules. Prof. Dr. Martin Zacharias Lehrstuhl für Molekulardynamik (T38) Technische Universität München
Structure formation and association of biomolecules Prof. Dr. Martin Zacharias Lehrstuhl für Molekulardynamik (T38) Technische Universität München Motivation Many biomolecules are chemically synthesized
More informationName: TOC#. Data and Observations: Figure 1: Amino Acid Positions in the Hemoglobin of Some Vertebrates
Name: TOC#. Comparing Primates Background: In The Descent of Man, the English naturalist Charles Darwin formulated the hypothesis that human beings and other primates have a common ancestor. A hypothesis
More informationBio 451 Examination I September 22, 1995
Bio 451 Examination I September 22, 1995 PLEASE PRINT YOUR NAME CLEARLY ON EVERY PAGE OF THIS EXAMINATION; IF THIS IS NOT DONE, WE WILL SET YOUR EXAM ASIDE WHEN THE EXAMS ARE TAKEN APART FOR GRADING. Answer
More informationCHAPTER 1. DNA: The Hereditary Molecule SECTION D. What Does DNA Do? Chapter 1 Modern Genetics for All Students S 33
HPER 1 DN: he Hereditary Molecule SEION D What Does DN Do? hapter 1 Modern enetics for ll Students S 33 D.1 DN odes For Proteins PROEINS DO HE nitty-gritty jobs of every living cell. Proteins are the molecules
More informationLecture 19A. DNA computing
Lecture 19A. DNA computing What exactly is DNA (deoxyribonucleic acid)? DNA is the material that contains codes for the many physical characteristics of every living creature. Your cells use different
More informationKey Concept Translation converts an mrna message into a polypeptide, or protein.
8.5 Translation VOBLRY translation codon stop codon start codon anticodon Key oncept Translation converts an mrn message into a polypeptide, or protein. MIN IDES mino acids are coded by mrn base sequences.
More informationMolecular Biology. Biology Review ONE. Protein Factory. Genotype to Phenotype. From DNA to Protein. DNA à RNA à Protein. June 2016
Molecular Biology ONE Sami Khuri Department of Computer Science San José State University Biology Review DNA RNA Proteins Central Dogma Transcription Translation Genotype to Phenotype Protein Factory DNA
More informationEE550 Computational Biology
EE550 Computational Biology Week 1 Course Notes Instructor: Bilge Karaçalı, PhD Syllabus Schedule : Thursday 13:30, 14:30, 15:30 Text : Paul G. Higgs, Teresa K. Attwood, Bioinformatics and Molecular Evolution,
More informationThe study of protein secondary structure and stability at equilibrium ABSTRACT
The study of protein secondary structure and stability at equilibrium Michelle Planicka Dept. of Physics, North Georgia College and State University, Dahlonega, GA REU, Dept. of Physics, University of
More informationHow life. constructs itself.
How life constructs itself Life constructs itself using few simple rules of information processing. On the one hand, there is a set of rules determining how such basic chemical reactions as transcription,
More informationSolutions to Problem Set 1
MIT Department of Biology 7.014 Introductory Biology, Spring 004 Question 1 Solutions to 7.014 Problem Set 1 a) Describe the conditions of the atmosphere on prebiotic earth and how these conditions differ
More informationAPPENDIX. Appendix. Table of Contents. Ethics Background. Creating Discussion Ground Rules. Amino Acid Abbreviations and Chemistry Resources
Appendix Table of Contents A2 A3 A4 A5 A6 A7 A9 Ethics Background Creating Discussion Ground Rules Amino Acid Abbreviations and Chemistry Resources Codons and Amino Acid Chemistry Behind the Scenes with
More informationFrom mechanism to medicne
From mechanism to medicne a look at proteins and drug design Chem 342 δ δ δ+ M 2009 δ+ δ+ δ M Drug Design - an Iterative Approach @ DSU Structural Analysis of Receptor Structural Analysis of Ligand-Receptor
More informationBasics of Protein Structure: Short Introduction to Molecular Structures
DNA/Proteinstructure function analysisandprediction BasicsofProteinStructure: 11Jan2006 ShortIntroductionto MolecularStructures Introductionto ProteinStructure Chapters1to5 CarlBranden& JohnTooze ISBN:0
More informationProtein Structure Prediction by Constraint Logic Programming
MPRI C2-19 Protein Structure Prediction by Constraint Logic Programming François Fages, Constraint Programming Group, INRIA Rocquencourt mailto:francois.fages@inria.fr http://contraintes.inria.fr/ Molecules
More informationA Zero-Knowledge Based Introduction to Biology
A Zero-Knowledge Based Introduction to Biology Konstantinos (Gus) Katsiapis 25 Sep 2009 Thanks to Cory McLean and George Asimenos Cells: Building Blocks of Life cell, membrane, cytoplasm, nucleus, mitochondrion
More informationBIL 256 Cell and Molecular Biology Lab Spring, 2007 BACKGROUND INFORMATION I. PROTEIN COMPOSITION AND STRUCTURE: A REVIEW OF THE BASICS
BIL 256 Cell and Molecular Biology Lab Spring, 2007 BACKGROUND INFORMATION I. PROTEIN COMPOSITION AND STRUCTURE: A REVIEW OF THE BASICS Proteins occupy a central position in the structure and function
More informationDet matematisk-naturvitenskapelige fakultet
UNIVERSITETET I OSLO Det matematisk-naturvitenskapelige fakultet Exam in: MBV4010 Arbeidsmetoder i molekylærbiologi og biokjemi I MBV4010 Methods in molecular biology and biochemistry I Day of exam: Friday
More information2018 Protein Modeling Exam Key
2018 Protein Modeling Exam Key Multiple Choice: 1. Which of the following amino acids has a negative charge at ph 7? a. Gln b. Glu c. Ser d. Cys 2. Which of the following is an example of secondary structure?
More informationThe combination of a phosphate, sugar and a base forms a compound called a nucleotide.
History Rosalin Franklin: Female scientist (x-ray crystallographer) who took the picture of DNA James Watson and Francis Crick: Solved the structure of DNA from information obtained by other scientist.
More informationBME205: Lecture 2 Bio systems. David Bernick
BME205: Lecture 2 Bio systems David Bernick Bioinforma;cs Infer pa>erns from life biological sequences structures molecular pathways. Suggest hypotheses from inferred pa>erns Structure and Func;on Novel
More informationZool 3200: Cell Biology Exam 3 3/6/15
Name: Trask Zool 3200: Cell Biology Exam 3 3/6/15 Answer each of the following questions in the space provided; circle the correct answer or answers for each multiple choice question and circle either
More informationCS 4491/CS 7990 SPECIAL TOPICS IN BIOINFORMATICS
1 CS 4491/CS 7990 SPECIAL TOPICS IN BIOINFORMATICS * Some contents are adapted from Dr. Jean Gao at UT Arlington Mingon Kang, PhD Computer Science, Kennesaw State University 2 Genetics The discovery of
More informationWhat is necessary for life?
Life What is necessary for life? Most life familiar to us: Eukaryotes FREE LIVING Or Parasites First appeared ~ 1.5-2 10 9 years ago Requirements: DNA, proteins, lipids, carbohydrates, complex structure,
More information36. The double bonds in naturally-occuring fatty acids are usually isomers. A. cis B. trans C. both cis and trans D. D- E. L-
36. The double bonds in naturally-occuring fatty acids are usually isomers. A. cis B. trans C. both cis and trans D. D- E. L- 37. The essential fatty acids are A. palmitic acid B. linoleic acid C. linolenic
More informationChemistry 121 Winter 17
Chemistry 121 Winter 17 Introduction to Organic Chemistry and Biochemistry Instructor Dr. Upali Siriwardane (Ph.D. Ohio State) E-mail: upali@latech.edu Office: 311 Carson Taylor Hall ; Phone: 318-257-4941;
More informationLIST OF ACRONYMS & ABBREVIATIONS
LIST OF ACRONYMS & ABBREVIATIONS ALA ARG ASN ATD CRD CYS GLN GLU GLY GPCR HIS hstr ILE LEU LYS MET mglur1 NHDC PDB PHE PRO SER T1R2 T1R3 TMD TRP TYR THR 7-TM VFTM ZnSO 4 Alanine, A Arginine, R Asparagines,
More informationAipotu I & II: Genetics & Biochemistry
Aipotu I & II: Genetics & Biochemistry Objectives: To reinforce your understanding of Genetics, Biochemistry, and Molecular Biology To show the connections between these three disciplines To show how these
More informationWhat is necessary for life?
Life What is necessary for life? Most life familiar to us: Eukaryotes FREE LIVING Or Parasites First appeared ~ 1.5-2 10 9 years ago Requirements: DNA, proteins, lipids, carbohydrates, complex structure,
More informationName. Student ID. Midterm 2, Biology 2020, Kropf 2004
Midterm 2, Biology 2020, Kropf 2004 1 1. RNA vs DNA (5 pts) The table below compares DNA and RNA. Fill in the open boxes, being complete and specific Compare: DNA RNA Pyrimidines C,T C,U Purines 3-D structure
More informationThe Effect of Using Different Neural Networks Architectures on the Protein Secondary Structure Prediction
The Effect of Using Different Neural Networks Architectures on the Protein Secondary Structure Prediction Hanan Hendy, Wael Khalifa, Mohamed Roushdy, Abdel Badeeh Salem Computer Science Department, Faculty
More informationHe who asks is a fool for five minutes, but he who does not ask remains a fool forever. Today. Admin Stuff. CSE527 Computational Biology
CSE527 Computational Biology http://www.cs.washington.edu/527 He who asks is a fool for five minutes, but he who does not ask remains a fool forever. Larry Ruzzo Autumn 2006 -- Chinese Proverb UW CSE Computational
More informationPrimordial soup was edible: abiotically produced Miller-Urey mixture. supports bacterial growth
Primordial soup was edible: abiotically produced Miller-Urey mixture supports bacterial growth Supplementary Materials Xueshu Xie 1, Daniel Backman 1, Albert T. Lebedev 2, Viatcheslav B. Artaev 3, Liying
More informationBIOLOGY. Monday 14 Mar 2016
BIOLOGY Monday 14 Mar 2016 Entry Task List the terms that were mentioned last week in the video. Translation, Transcription, Messenger RNA (mrna), codon, Ribosomal RNA (rrna), Polypeptide, etc. Agenda
More informationDaily Agenda. Warm Up: Review. Translation Notes Protein Synthesis Practice. Redos
Daily Agenda Warm Up: Review Translation Notes Protein Synthesis Practice Redos 1. What is DNA Replication? 2. Where does DNA Replication take place? 3. Replicate this strand of DNA into complimentary
More informationAipotu I: Genetics & Biochemistry
Aipotu I: Genetics & Biochemistry Objectives: To reinforce your understanding of Genetics, Biochemistry, and Molecular Biology To show the connections between these three disciplines To show how these
More informationLezione 10. Bioinformatica. Mauro Ceccanti e Alberto Paoluzzi
Lezione 10 Bioinformatica Mauro Ceccanti e Alberto Paoluzzi Dip. Informatica e Automazione Università Roma Tre Dip. Medicina Clinica Università La Sapienza Lezione 10: Sintesi proteica Synthesis of proteins
More informationName Date of Data Collection. Class Period Lab Days/Period Teacher
Comparing Primates (adapted from Comparing Primates Lab, page 431-438, Biology Lab Manual, by Miller and Levine, Prentice Hall Publishers, copyright 2000, ISBN 0-13-436796-0) Background: One of the most
More informationHe who asks is a fool for five minutes, but he who does not ask remains a fool forever. Tonight. Admin Stuff. CSEP590A Computational Biology
CSEP590A Computational Biology http://www.cs.washington.edu/csep590a He who asks is a fool for five minutes, but he who does not ask remains a fool forever. Larry Ruzzo Summer 2006 -- Chinese Proverb UW
More informationHe who asks is a fool for five minutes, but he who does not ask remains a fool forever. Today. Admin Stuff. CSE527 Computational Biology
CSE527 Computational Biology http://www.cs.washington.edu/527 He who asks is a fool for five minutes, but he who does not ask remains a fool forever. Larry Ruzzo Autumn 2007 -- Chinese Proverb UW CSE Computational
More informationNatural Capital Protocol in Practice Ajinomoto
Natural Capital Protocol in Practice Ajinomoto Ajinomoto Co., Inc. Global Communications dept CSR group Mr. Keiji NAKAMURA 1. Introduction of Ajinomoto Group (1) Outline The Aspiration of the Ajinomoto
More information蛋白質體學. Proteomics Amino acids, Peptides and Proteins 陳威戎 & 21
蛋白質體學 Proteomics 2015 Amino acids, Peptides and Proteins 陳威戎 2015. 09. 14 & 21 Outline 1. Amino Acids 2. Peptides and Proteins 3. Covalent Structure of Proteins Amino Acids Proteins are polymers of amino
More informationTHE GENETIC CODE Figure 1: The genetic code showing the codons and their respective amino acids
THE GENETIC CODE As DNA is a genetic material, it carries genetic information from cell to cell and from generation to generation. There are only four bases in DNA and twenty amino acids in protein, so
More informationThe Nature of Life. Some properties of life. Copyright 2005 Pearson Education, Inc. publishing as Benjamin Cummings
The Nature of Life Some properties of life opyright 2005 Pearson Education, Inc. publishing as Benjamin ummings Life Displays rder opyright 2005 Pearson Education, Inc. publishing as Benjamin ummings Life
More informationCECS Introduction to Bioinformatics University of Louisville Spring 2004 Dr. Eric Rouchka
Dr. Awwad Abdoh Radwan Dept Pharm Organic Chemistry, Faculty of Pharmacy, Assiut University. 29/09/2005 Required Texts Image Source: http://www.amazon.com/ Other Bioinformatics Books Image Source: http://www.amazon.com/
More informationToday He who asks is a fool for five minutes, but he who does not ask remains a fool forever.
CSE527 Computational Biology http://www.cs.washington.edu/527 Larry Ruzzo Autumn 2009 UW CSE Computational Biology Group Today He who asks is a fool for five minutes, but he who does not ask remains a
More informationBiology: The substrate of bioinformatics
Bi01_1 Unit 01: Biology: The substrate of bioinformatics What is Bioinformatics? Bi01_2 handling of information related to living organisms understood on the basis of molecular biology Nature does it.
More informationCase 7 A Storage Protein From Seeds of Brassica nigra is a Serine Protease Inhibitor
Case 7 A Storage Protein From Seeds of Brassica nigra is a Serine Protease Inhibitor Focus concept Purification of a novel seed storage protein allows sequence analysis and determination of the protein
More informationSMIBIO Case Study in Germany - Green Biorefineries in the Bavarian region of Straubing-Bogen (a case study in progress)
SMIBIO Case Study in Germany - Green Biorefineries in the Bavarian region of Straubing-Bogen (a case study in progress) SMIBIO Workshop Small-scale Biorefineries for Rural Development in Latin America
More informationCOMMENTS TO THE AMINO ACID SEQUENCE OF YEAST G LYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE
Carlsberg Res. Commun. Vol. 45, p. 195-200, 1980 COMMENTS TO THE AMINO ACID SEQUENCE OF YEAST G LYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE by STEPHEN BAYNE l, BRIAN MARTIN 2 and IB SVENDSEN Department of
More informationForensic Science: DNA Evidence Unit
Day 2 : Cooperative Lesson Topic: Protein Synthesis Duration: 55 minutes Grade Level: 10 th Grade Forensic Science: DNA Evidence Unit Purpose: The purpose of this lesson is to review and build upon prior
More informationFROM DNA TO GENETIC GENEALOGY Stephen P. Morse
1. GENES, CHROMOSOMES, AND DNA Chromosomes FROM DNA TO GENETIC GENEALOGY Stephen P. Morse (steve@stevemorse.org) Every human cell = 46 chromosomes (1 to 22 in pairs, 2 sex chromosomes) Male: sex chromosomes
More informationConnect the dots DNA to DISEASE
Teachers Material Connect the dots DNA to DISEASE Developed by: M. Oltmann & A. James. California State Standards Cell Biology 1.d. Students know the central dogma of molecular biology outlines the flow
More informationChapter 10. The Structure and Function of DNA. Lectures by Edward J. Zalisko
Chapter 10 The Structure and Function of DNA PowerPoint Lectures for Campbell Essential Biology, Fifth Edition, and Campbell Essential Biology with Physiology, Fourth Edition Eric J. Simon, Jean L. Dickey,
More information27 Molecular genetics
Class: Name: ( ) Date: 27 Molecular genetics 27.1 From DNA to proteins (Book 4, p. 27-3) A The genetic code (Book 4, p. 27-3) The base sequence of DNA determines the amino acid sequence in a polypeptide
More informationIn silico measurements of twist and bend. moduli for beta solenoid protein self-
In silico measurements of twist and bend moduli for beta solenoid protein self- assembly units Leonard P. Heinz, Krishnakumar M. Ravikumar, and Daniel L. Cox Department of Physics and Institute for Complex
More informationCase 7 A Storage Protein From Seeds of Brassica nigra is a Serine Protease Inhibitor Last modified 29 September 2005
Case 7 A Storage Protein From Seeds of Brassica nigra is a Serine Protease Inhibitor Last modified 9 September 005 Focus concept Purification of a novel seed storage protein allows sequence analysis and
More informationSpeaker: Yu-Chen Ku Professor: Ching-Tsan Huang, Ph. D. Source: Biochemical Journal (2007) 402, Date: December 4th, 2007
Directed evolution and structural analysis of N-carbamoyl-D-amino acid amidohydrolase provide insights into recombinant protein solubility in Escherichia coli Speaker: Yu-Chen Ku Professor: Ching-Tsan
More informationDNA is normally found in pairs, held together by hydrogen bonds between the bases
Bioinformatics Biology Review The genetic code is stored in DNA Deoxyribonucleic acid. DNA molecules are chains of four nucleotide bases Guanine, Thymine, Cytosine, Adenine DNA is normally found in pairs,
More informationSYKAM Amino Acid Analyzer
C H R O M AT O G R A P H Y SYKAM Amino Acid Analyzer Automatic Amino Acid Analyzer S 433 The innovative automatic Amino Acid Analyzer S 433 combines the advantages of the classical ion exchange separation
More informationVisualizing proteins with PyMol
Visualizing proteins with PyMol Structural Bioinformatics GENOME 541 Spring 2018 Lecture 1: Protein Structure Frank DiMaio (dimaio@uw.edu) Obtaining PyMOL We will use an educational build of PyMOL that
More informationCreate a model to simulate the process by which a protein is produced, and how a mutation can impact a protein s function.
HASPI Medical Biology Lab 0 Purpose Create a model to simulate the process by which a protein is produced, and how a mutation can impact a protein s function. Background http://mssdbio.weebly.com/uploads/1//7/6/17618/970_orig.jpg
More information7.013 Spring 2005 Problem Set 1
MIT Department of Biology 7.013: Introductory Biology Spring 005 Instructors: rofessor azel Sive, rofessor Tyler Jacks, Dr. laudette Gardel AME TA Section # 7.013 Spring 005 roblem Set 1 FRIDAY February
More informationSTRUCTURE, DYNAMICS AND INTERACTIONS OF PROTEINS BY NMR SPECTROSCOPY
STRUCTURE, DYNAMICS AND INTERACTIONS OF PROTEINS BY NMR SPECTROSCOPY Constantin T. Craescu INSERM & Institut Curie - Recherche Orsay, France A SHORT INTRODUCTION TO PROTEIN STRUCTURE Chemical composition
More informationAmino Acid Sequences and Evolutionary Relationships
Amino Acid Sequences and Evolutionary Relationships One technique used to determine evolutionary relationships is to study the biochemical similarity of organisms. Though molds, aardvarks, and humans appear
More informationCSEP 590 B Computational Biology. Genes and Gene Prediction
CSEP 590 B Computational Biology Genes and Gene Prediction 1 Some References (more on schedule page) A good intro survey JM Claverie (1997) "Computational methods for the identification of genes in vertebrate
More informationTranscription & Translation Practice Examination
Name: Date: Students must provide an explanation for all problems. Students must have parent signature prior to submission. 1. A DNA molecule with the base sequence A-G-C-T-C-A was used as a template for
More information