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1 CambridgeSoft Solutions BioDraw Ultra 11.0 High Quality Sequence and Pathway Drawing Jesse Gordon Director, Biology Marketing Skype; jessegordon

2 BioDraw Ultra 11.0 Presentation Agenda ChemBioOffice Ultra 2008 Desktop Suite Introduction ChemBioDraw Ultra 11.0 Integrated Chemistry and Biology Communication Tool BioDraw Features Biological Pathway Drawing Freehand Pen Tool Flexible Arrows New Plasmid Map Tool ChemBioDraw Sequence Tool Customizable Templates Extended Platform Support Windows Vista MSOffice 2007 Native support of Intel on Mac

3 ChemBioOffice 2008 Applications - The Desktop Productivity Suite for Scientists The ultimate chemistry & biology suite, designed to meet the needs of both chemists and biologists ChemBioViz Ultra Suite ChemBioDraw Ultra 11.0 ChemBio3D Ultra 11.0 ChemFinder/BioViz Ultra 11.0 with support for Oracle MestReC Std ChemScript Pro 11.0 ChemDraw/Excel 11.0 CombiChem/Excel 11.0 ChemDraw & Chem3D ActiveX Pro Plugins & Controls 11.0 ChemINDEX (Index, RXN, NCI & AIDS) 1-year subscriptions to ChemACX and epub BioAssay Ultra 11.0 Inventory Ultra 11.0 E-Notebook Ultra 11.0

4 Integrate Chemistry and Biology Drawings - Facilitate Communication between Scientists BioDraw features are fully integrated into ChemBioDraw Ultra Use any BioDraw tool in any ChemDraw document Excellent collaborative tool

5 Integrate Chemistry and Biology Drawings - Facilitate Communication between Scientists Draw Biological Pathways One or Two-substrate enzyme Receptor Ion Channel Helix Protein Linear membrane Arc membrane Golgi body Cloud G-Protein (alpha, beta or gamma subunit) Immunoglobin DNA Micelle Ellipse membrane Endoplasmic Reticulum Mitochondrion

6 Highest Presentation Quality Graphics - Intuitive Freehand sketching tool The toolbar contains two items, Draw Curve (default) and Edit Curve Holding the Shift key reduces the amount of smoothness The curves created can be further modified by selecting and dragging control points New in v11

7 Highest Presentation Quality Graphics - Adjustable Shapes, Arrows and more Arrow Types include: No-go, unbalanced equilibrium, dipole, multiple arrowheads Adjustable Arrows Full control over arrow properties including Curves, color fill and shading - illustrate complex chemistry/biology mechanisms Rotatable and adjustable geometric shapes rectangles and ovals Color-faded geometric shapes rectangles and ovals

8 BioDraw New Drawing tools - Enhanced illustration of biological processes New trna Tool New Ribosome Tool New Plasmid Maps DNA helix strands can now be selected individually for modification Protein helix strands and cylinders can now be individually selected and modified

9 Annotations - Add information to Objects in ChemBioDraw The Annotation tool allows the user to add information to objects. The information will be stored and show as a keyword and content Keyword: will describe the type of information Content: will contain the information. A list of keywords has been pre-defined (Description, Name, Other Info, and Type) The user also has the option to add new keywords

10 ChemBioDraw Sequence tool - Easily Create Amino Acid, DNA, RNA sequences Draw peptide and nucleotide sequences Several modes: - Single-letter amino acid tool - Three-letter amino acid tool - DNA tool - RNA tool Termini are labeled depending on the type of sequence drawn Expand and contract single or multiple labels and sequences H H N A O NH 2 HS N H Ala Cys Gly Thr C O H N G O N H T COOH OH O OH

11 Work faster with ChemBioDraw - ChemBioDraw Reduces Drawing Time Customizable Templates Complex structures and pathways can take seconds to draw vs. minutes Save hours by creating and saving custom structure and pathway template drawings Share custom templates with colleagues

12 ChemBioOffice Annual Site License -Cost Effective Collaboration Unlimited usage within institution (hence lower cost per user) All departments have access to the specific software they need Software updates and administrator support included Software can be used on any machine (lab, laptop, home use) Individual online software download means less administration Site licenses reduce support load Multi-year site licenses reduce long-term cost

13 CambridgeSoft Solutions BioDraw 11.0 High Quality Sequence and Pathway Drawing Jesse Gordon Director, Biology Marketing Skype; jessegordon

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