Keller and Heckman LLP Serving Business through Law and Science. Genetically Modified Organisms and TSCA
|
|
- Amice Jacobs
- 6 years ago
- Views:
Transcription
1 Keller and Heckman LLP Serving Business through Law and Science Genetically Modified Organisms and TSCA
2 The Technology Biotechnology s role in sustainable environment Concern: novel behaviors, in some instances, may present a risk to human health or the environment Certain uses assessed under TSCA
3 The Technology Traditional mutation techniques inefficient, difficult to target to specific traits Traits that enhance production or quality in other species can be identified and transferred through biotechnology Yield increased, greater efficiency Leads to new and improved end products
4 source: EPA (Aug. 2003)
5 Categories of Biotechnology (for regulatory purposes) Microorganisms have been employed by business, universities, and government to meet certain R&D and commercial needs for years Majority of these applications are outside TSCA s jurisdiction
6 Regulatory Categories Specifically excluded from TSCA - Foods and beverages Medical applications Pesticides
7 source: EPA (Aug. 2003) Health New Products Feed Processing Agronomic Traits Chemicals
8 TSCA Regulated Uses TSCA 3(2)(A) definition of chemical substance includes microorganisms Any organic or inorganic substance of a particular molecular identity... About 10 percent of the overall market (source: EPA Reg. Impact Anal. (1997))
9 TSCA Regulated Uses Enzyme production, other chemicals in contained fermentation systems Key monomers in polyesters Polymer-grade acrylamide EPA view - High fructose corn syrup industry created by use of these enzymes
10 Polylactic acid
11 Other TSCA Uses Treatment of biological waste Field application to enhance nitrogen fixation on crops (soybeans, alfalfa) Bioethanol, biodiesel
12 Bioethanol
13 The Third Wave source EPA (Aug. 2003)
14 TSCA Rules New, intergenetic microorganisms 40 C.F.R. Part 725; 62 Fed. Reg (April 11, 1997) commercial uses and commercial R&D some old, some new, exemptions significant new use rules (none yet) Must also establish TSCA status for Other feedstocks Reaction product (e.g., the polymer)
15 Defined terms: Microorganism Organism in the kingdoms of Monera (Procaryotae), Protista, Fungi, the Chlorophyta and Rhodophyta of the Plantae, and a virus or virus-like particles Includes bacteria Does not include cell cultures of human cells.
16 Defined terms: Intergeneric Formed by deliberately combining genetic material first isolated in a different taxonomic genus Deliberate combination of certain mobile genetic elements (DNA) Does not include well-characterized, noncoding regulatory regions from another genus If not intergeneric on the TSCA Inventory
17 Defined terms: Noncoding Region A segment of introduced genetic material for which The regulatory region and any inserted flanking nucleotides do not code for a protein, peptide, or functional ribonucleic acid molecules and The regulatory region solely control the activity of other regions Operators, promoters, terminators, etc.
18 Defined terms: Mobil genetic element An element of genetic material that has the ability to move genetic material within and between organisms, including plasmids, viruses, insertion sequences
19 Microbial Commercial Activity Notice (MCAN) 90 day review Requirements recipient and new miccroorganism Genetic construction Phenotypic and ecological characteristics (e.g., habitat, distribution, source) Byproducts Production volume, use, worker exposure Existing data Need to file NOC to place on Inventory Upfront" CBI substantiation
20 Traditional Exemptions FFDCA, FIFRA regulated uses Mixtures (components not exempt) Manufactured and processed solely for export and labeled accordingly
21 Non-commercial R&D Exempt Microorganisms manufactured, imported, or processed for noncommercial purposes, e.g., solely for academic research 40 C.F.R
22 Non-commercial R&D Exempt Commercial indicators company contracts directly with a researcher company gives a conditional grant where the company holds patent rights, or establishes a joint venture where the company has the patent or licensing rights
23 Non-commercial R&D Exempt Commercial if the researcher is not funded directly, but intends to obtain an immediate or eventual commercial advantage, e.g. developing a commercially viable improvement of a product on the market has sought or is seeking commercial funding for commercial development has sought or is seeking a patent
24 Commercial R&D Exemptions Contained structure exemption ( ) National Institutes of Health Guidelines for Research Involving Recombinant DNA Molecules ("NIH Guidelines") ( ) Outside a structure/2 strains ( ) Rhizobium meliloti Bradyrhizobium japonicum TSCA Experimental Release Application (TERA) for other releases ( )
25 TERA - 60 day review Organizations manufacturing, importing, or processing "new" microorganisms intended for use in commercial R&D in the environment Identity of organism Phenotypic and ecological characteristics Description of R&D includes # organisms released, target organisms All available data Records must be kept 3 years Report to EPA w/in 1 year
26 Exemptions for Commercial Use Beyond R&D Test Market Same as Traditional (45 day review) Contained Structure/Well- Characterized Microorganisms Tier I Tier II
27 Well-characterized The function of the genetic material has been determined. Includes - Acetobacter aceti Aspergillus niger Asplergillus oryzae Bacillus lichenformis Bacillus subtilis Clostridium acetobutylicum Escherichia coli K-12 Penicillium roqueforti, Saccharomyces cerevisiae Saccharomyces uvarum
28 Well-characterized Limited in the genetic material that can be introduced (e.g., regulatory sequence permitting the expression of solely the genes of interest) Poorly mobilizable Free of encoding sequence for polypeptides that contribute to a toxic effect (list of prohibited sequences)
29 Other Conditions Tier I No filing required... SO LONG AS containment meets EPA specifications system designed to contain organisms controlled access written, published, an implemented safety procedures inactivation procedures steps to minimize release through aerosols and exhaust, other routes emergency clean up
30 Other Conditions Tier II Day Review Affirmative request submitted to EPA If different containment is used
31 SUMMARY Not many MCAN filings so far Many activities qualify for the exemptions Non-confidential MCANs And TERAs biotech_rule/submiss.htm
Coordinated Framework and EPA Oversight of Biotechnology
Coordinated Framework and EPA Oversight of Biotechnology Mark Segal, Ph. D. FACILITATING SAFE AND SECURE SCIENCE Practical Approaches for IBCs June 16-19, 2013 Seattle, WA 1 The Coordinated Framework The
More informationRegulation of Biotechnology
Section V 1988-2009 Environment Books Inc. Page D1 Regulation of Biotechnology Summary of the Requirement: Any person who intends to manufacture or import for commercial purposes 1 a new 2 living microorganism
More informationTHE BENEFITS AND USES OF MICROBES
MODULE 4 MICROBES AND MICROBIAL BIOTECHNOLOGY U N I T 2 THE BENEFITS AND USES OF MICROBES A. MICROBIAL BIOTECHNOLOGY 1 Read What is biotechnology? and decide which of the words below can be used instead
More informationSafe Operating Procedure
Safe Operating Procedure RECOMBINANT OR SYNTHETIC NUCLEIC ACIDS IBC AND OTHER REVIEW REQUIREMENTS (For assistance, please contact EHS at (402) 472-4925, or visit our web site at http://ehs.unl.edu/) (Revised
More informationOrganic Materials Review Institute
Organic Materials Review Institute Genetic Engineering Considerations in the Evaluation of Inputs for Organic Farming and Food Processing A Policy in Development December 11, 2000 Box 11558 Eugene OR 97440
More informationRegulation of Agricultural Biotechnology in the United States: Overview
Regulation of Agricultural Biotechnology in the United States: Overview Webinar for: National Agricultural Law Center July 15, 2015 Michael J. Firko, Ph.D. APHIS Deputy Administrator (BRS) History of Plant
More informationIBC protocol Risk Assessment and Determination of NIH Guidelines
IBC protocol Risk Assessment and Determination of NIH Guidelines The following are points to consider when reviewing all protocols for risk, recommended containment conditions, and determine applicable
More informationUSDA-APHIS Biotechnology Regulatory Services Janet L. Bucknall Associate Deputy Administrator
USDA-APHIS Biotechnology Regulatory Services Janet L. Bucknall Associate Deputy Administrator National Conference of State Legislatures Capitol Forum, Washington DC December 8, 2015 USDA APHIS BRS Mission
More informationGenetics Lecture 21 Recombinant DNA
Genetics Lecture 21 Recombinant DNA Recombinant DNA In 1971, a paper published by Kathleen Danna and Daniel Nathans marked the beginning of the recombinant DNA era. The paper described the isolation of
More informationMicrobial Biotechnology agustin krisna wardani
Microbial Biotechnology agustin krisna wardani 1. The Structure of Microbes Microbes (microorganisms) are tiny organisms that are too small to be seen individually by the naked eye and must be viewed with
More informationBiosafety and the NIH Guidelines
Biosafety and the NIH Guidelines This section will explore: Why the NIH Guidelines are important The definition of recombinant or synthetic nucleic acid research Content of the NIH Guidelines Section III
More informationSafety evaluation of technical enzyme products. legislation. 09 June 2009 Brussels
Safety evaluation of technical enzyme products with regards to the REACH legislation 09 June 2009 Brussels ENZYMES What enzymes are Enzymes are proteins with highly specialized catalytic function Produced
More informationRegulation of New Plant Breeding Techniques in Canada and the United States
Regulation of New Plant Breeding Techniques in Canada and the United States New Breeding Techniques RNA interference Cisgenesis and intragenesis Oligonucleotide directed mutagenesis Grafting (on transgenic
More informationREGISTRATION DOCUMENT FOR RECOMBINANT DNA RESEARCH
EHRS Date Received: Reg. Doc. No.: REGISTRATION DOCUMENT FOR RECOMBINANT DNA RESEARCH Principal Investigator: Penn ID#: Position Title: School: Department: Mailing Address: Mail Code: Telephone: FAX: E-mail:
More informationUSDA Regulation of Organisms Developed Through Modern Breeding Technologies
USDA Regulation of Organisms Developed Through Modern Breeding Technologies Neil E. Hoffman USDA-Animal and Plant Health Inspection Service Riverdale, Maryland neil.e.hoffman@aphis.usda.gov The federal
More informationRNA and Protein Synthesis
RNA and Protein Synthesis CTE: Agriculture and Natural Resources: C5.3 Understand various cell actions, such as osmosis and cell division. C5.4 Compare and contrast plant and animal cells, bacteria, and
More informationBIOLOGY LTF DIAGNOSTIC TEST DNA to PROTEIN & BIOTECHNOLOGY
Biology Multiple Choice 016074 BIOLOGY LTF DIAGNOSTIC TEST DNA to PROTEIN & BIOTECHNOLOGY Test Code: 016074 Directions: Each of the questions or incomplete statements below is followed by five suggested
More informationBiological Inventions
Note: When any ambiguity of interpretation is found in this provisional translation, the Annex B Japanese text shall prevail. Chapter 2 Biological Inventions In this chapter, the application of Examination
More informationOECD and Substantial Equivalence Peter Kearns, OECD
OECD and Substantial Equivalence Peter Kearns, OECD 28 March 2011 Transgenic plants: milestones 1973: First successful recombinant DNA experiment using bacterial genes 1985: First transgenic plant resistant
More informationThe summer of 2015 was surprisingly busy in the industrial
Commentary Industrial Biotechnology: Coordinated Framework Make-Over and Lots More Lynn L. Bergeson Bergeson & Campbell, PC, The Acta Group, and B&C Ò Consortia Management, LLC, Washington, DC The summer
More informationChapter 15 Gene Technologies and Human Applications
Chapter Outline Chapter 15 Gene Technologies and Human Applications Section 1: The Human Genome KEY IDEAS > Why is the Human Genome Project so important? > How do genomics and gene technologies affect
More informationDNA & Protein Synthesis UNIT D & E
DNA & Protein Synthesis UNIT D & E How this Unit is broken down Chapter 10.1 10.3 The structure of the genetic material Chapter 10.4 & 10.5 DNA replication Chapter 10.6 10.15 The flow of genetic information
More informationRegulations and safety assessment for genetically modified foods and feeds in Taiwan
Regulations and safety assessment for genetically modified foods and feeds in Taiwan Wen-Shen Chu Food Industry Research and Development Institute 21 July, 2016 1 Contents Overview of Taiwan Regulatory
More informationNOTES - CH 15 (and 14.3): DNA Technology ( Biotech )
NOTES - CH 15 (and 14.3): DNA Technology ( Biotech ) Vocabulary Genetic Engineering Gene Recombinant DNA Transgenic Restriction Enzymes Vectors Plasmids Cloning Key Concepts What is genetic engineering?
More informationBiotechnology. Chapter 17 section 1 (only)
Biotechnology Chapter 17 section 1 (only) 5-16-16 Learning Goals for Today: Explain how DNA profiling can identify individuals Interpret data from DNA electrophoresis Discuss genetically modified organisms
More informationPharma&Biotech. XS Microbial Expression Technologies Optimize Productivity, Speed and Process Robustness
Pharma&Biotech XS Microbial Expression Technologies Optimize Productivity, Speed and Process Robustness Embracing Complexity Based on 30 years of innovation in microbial biotechnology, Lonza offers the
More informationGenetic Engineering for Biofuels Production
Genetic Engineering for Biofuels Production WSE 573 Spring 2013 Greeley Beck INTRODUCTION Alternative transportation fuels are needed in the United States because of oil supply insecurity, oil price increases,
More information3. INHERITED MUTATIONS
THE CENTRAL DOGMA OF BIOLOGY 1. DNA B4.2 The genetic information encoded in DNA molecules provides instructions for assembling protein molecules. Genes are segments of DNA molecules. Inserting, deleting,
More informationChapter 13 - Concept Mapping
Chapter 13 - Concept Mapping Using the terms and phrases provided below, complete the concept map showing the discovery of DNA structure. amount of base pairs five-carbon sugar purine DNA polymerases Franklin
More informationMolecular assessment of GMOs Ilona Kryspin Sørensen PhD DTU Food Division for Risk Assessment and Nutrition
Molecular assessment of GMOs Ilona Kryspin Sørensen PhD DTU Food Division for Risk Assessment and Nutrition Objective : to assess the level of documentation necessary for the evaluation of the insertion
More informationTutorial for Completing Penn s r s DNA Registration Document
NIH GUIDELINES FOR RESEARCH INVOLVING RECOMBINANT OR SYNTHETIC NUCLEIC ACID MOLECULES NIH GUIDELINES Tutorial for Completing Penn s r s DNA Registration Document Revision March 7, 2013 Penn s r s DNA Registration
More informationBiotechnology and Genomics in Public Health. Sharon S. Krag, PhD Johns Hopkins University
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike License. Your use of this material constitutes acceptance of that license and the conditions of use of materials on this
More informationPractice Test #3. Multiple Choice Identify the choice that best completes the statement or answers the question.
Practice Test #3 Multiple Choice Identify the choice that best completes the statement or answers the question. 1. An application of using DNA technology to help environmental scientists would be _. a.
More informationGenome Editing Deals in Agriculture
Genome Editing Deals in Agriculture Key Issues and Potential Pitfalls John R. Therien, J.D. October 24, 2017 Genome Editing Deals in Ag Licensing and R&D collaborations based on GE tools for applications
More informationwhile Bacilli is the class to which the order Lactobacillales belongs to.
Interactive Questions Question 1: Lactic acid bacteria belong to which order? Lactobacillaceae Lactobacillales Lactobacillales is the correct order. Lactobacillaceae is one family within this order, while
More information8/21/2014. From Gene to Protein
From Gene to Protein Chapter 17 Objectives Describe the contributions made by Garrod, Beadle, and Tatum to our understanding of the relationship between genes and enzymes Briefly explain how information
More informationBIOTECHNOLOGY OLD BIOTECHNOLOGY (TRADITIONAL BIOTECHNOLOGY) MODERN BIOTECHNOLOGY RECOMBINANT DNA TECHNOLOGY.
BIOTECHNOLOGY Biotechnology can be defined as the use of micro-organisms, plant or animal cells or their components or enzymes from organisms to produce products and processes (services) useful to human
More informationSelf-test Quiz for Chapter 12 (From DNA to Protein: Genotype to Phenotype)
Self-test Quiz for Chapter 12 (From DNA to Protein: Genotype to Phenotype) Question#1: One-Gene, One-Polypeptide The figure below shows the results of feeding trials with one auxotroph strain of Neurospora
More informationRE: EPA-HQ-OPPT Comment on EPA's Draft Algae Guidance for the Preparation of TSCA Biotechnology Submissions
Matt Carr Executive Director 125 St. Paul Street P.O. Box 369 Preston, MN 55965-0369 (877)531-5512 mcarr@algaebiomass.org Jeffrey Morris Acting Director Office of Pollution Prevention and Toxics (OPPT)
More informationGenetics and Biotechnology Chapter 13
1 Genetics and Biotechnology Chapter 13 Selective breeding is used to produce organisms with desired traits. I. Applied Genetics A. Selective Breeding 1. Definedthe process by which desired traits of certain
More informationWHOLE FOODS MARKET GMO Labeling Policy
WHOLE FOODS MARKET GMO Labeling Policy VERSION 4.1 NOVEMBER 3, 2017 As of September 1, 2018, Whole Foods Market will require suppliers of food products to label products that contain genetically modified
More informationPROTEIN SYNTHESIS Flow of Genetic Information The flow of genetic information can be symbolized as: DNA RNA Protein
PROTEIN SYNTHESIS Flow of Genetic Information The flow of genetic information can be symbolized as: DNA RNA Protein This is also known as: The central dogma of molecular biology Protein Proteins are made
More informationCrop Science Society of America
Crop Science Society of America Grand Challenge Statements Crop science is a highly integrative science employing the disciplines of conventional plant breeding, transgenic crop improvement, plant physiology,
More informationSECTION I CITIZENSHIP: CITIZENSHIP: SECTION II
APPLICATION FOR INSTITUTIONAL BIOSAFETY COMMITTEE REVIEW AND APPROVAL South Dakota School of Mines and Technology (Protocol Submission Form) This form must be submitted for ALL research or teaching activities
More informationBio11 Announcements. Ch 21: DNA Biology and Technology. DNA Functions. DNA and RNA Structure. How do DNA and RNA differ? What are genes?
Bio11 Announcements TODAY Genetics (review) and quiz (CP #4) Structure and function of DNA Extra credit due today Next week in lab: Case study presentations Following week: Lab Quiz 2 Ch 21: DNA Biology
More informationChapter 10 - Molecular Biology of the Gene
Bio 100 - Molecular Genetics 1 A. Bacterial Transformation Chapter 10 - Molecular Biology of the Gene Researchers found that they could transfer an inherited characteristic (e.g. the ability to cause pneumonia),
More informationNIH Guidelines for rdna Research: Tutorial for Completing Penn s rdna Registration Document
NIH Guidelines for rdna Research: Tutorial for Completing Penn s rdna Registration Document Revision March 3, 2011 Penn s rdna Registration Document Dual Use Research Definition: Research that yields information
More informationWhat happens after DNA Replication??? Transcription, translation, gene expression/protein synthesis!!!!
What happens after DNA Replication??? Transcription, translation, gene expression/protein synthesis!!!! Protein Synthesis/Gene Expression Why do we need to make proteins? To build parts for our body as
More informationnumber Done by Corrected by Doctor Hamed Al Zoubi
number 3 Done by Neda a Baniata Corrected by Waseem Abu Obeida Doctor Hamed Al Zoubi Note: it is important to refer to slides. Bacterial genetics *The main concepts we will talk about in this lecture:
More informationLectures of Dr.Mohammad Alfaham. The Bacterial Genetics
Lectures of Dr.Mohammad Alfaham The Bacterial Genetics is the total collection of genes carried by a bacterium both on its chromosome and on its extrachromosomal genetic elements (plasmids) A Gene A gene
More informationDNA/RNA STUDY GUIDE. Match the following scientists with their accomplishments in discovering DNA using the statement in the box below.
Name: Period: Date: DNA/RNA STUDY GUIDE Part A: DNA History Match the following scientists with their accomplishments in discovering DNA using the statement in the box below. Used a technique called x-ray
More informationGenetic Engineering & Recombinant DNA
Genetic Engineering & Recombinant DNA Chapter 10 Copyright The McGraw-Hill Companies, Inc) Permission required for reproduction or display. Applications of Genetic Engineering Basic science vs. Applied
More informationBio 101 Sample questions: Chapter 10
Bio 101 Sample questions: Chapter 10 1. Which of the following is NOT needed for DNA replication? A. nucleotides B. ribosomes C. Enzymes (like polymerases) D. DNA E. all of the above are needed 2 The information
More informationAdvanced Plant Technology Program Vocabulary
Advanced Plant Technology Program Vocabulary A Below you ll find a list of words (and their simplified definitions) that our researchers use on a daily basis. Abiotic stress (noun): Stress brought on by
More informationGenetic Engineering: Transforming Bacteria
Genetic Engineering: Transforming Bacteria Introduction Activity Introduction In this laboratory experiment, students will transform the phenotype of bacteria through the use of genetic engineering. A
More informationO C. 5 th C. 3 rd C. the national health museum
Elements of Molecular Biology Cells Cells is a basic unit of all living organisms. It stores all information to replicate itself Nucleus, chromosomes, genes, All living things are made of cells Prokaryote,
More informationModule F06FB08. To gain knowledge about enzyme technology and production of enzymes and
Module F06FB08 Enzyme technology Introduction and Production of enzymes This module would focus on enzyme technology which deals with the enzymes, the metabolic catalysts and their use in various Industries.
More informationAGRO/ANSC/BIO/GENE/HORT 305 Fall, 2016 Overview of Genetics Lecture outline (Chpt 1, Genetics by Brooker) #1
AGRO/ANSC/BIO/GENE/HORT 305 Fall, 2016 Overview of Genetics Lecture outline (Chpt 1, Genetics by Brooker) #1 - Genetics: Progress from Mendel to DNA: Gregor Mendel, in the mid 19 th century provided the
More informationIS THE US FDA REGULATION AND EVALUATION OF GENETICALLY ENGINEEERED FOODS SUFFICIENT? Teresa Marek FOOD REGULATION IN THE UNITED STATES
IS THE US FDA REGULATION AND EVALUATION OF GENETICALLY ENGINEEERED FOODS SUFFICIENT? by Teresa Marek FOOD REGULATION IN THE UNITED STATES Professor Neal Fortin April 25, 2008-1 - IS THE US FDA REGULATION
More informationDNA: THE GENETIC MATERIAL
DNA: THE GENETIC MATERIAL This document is licensed under the Attribution-NonCommercial-ShareAlike 2.5 Italy license, available at http://creativecommons.org/licenses/by-nc-sa/2.5/it/ 1. Which macromolecule
More informationGenetically Modified Organisms II. How are transgenic plants generated? The components of T DNA transfer. Plants
Genetically Modified Organisms II Plants How are transgenic plants generated? The bacterium Agrobacterium tumefaciens is a pathogen of plants that causes crown gall tumors. Crown gall tumor Agrobacterium
More informationMolecular Genetics Student Objectives
Molecular Genetics Student Objectives Exam 1: Enduring understanding 3.A: Heritable information provides for continuity of life. Essential knowledge 3.A.1: DNA, and in some cases RNA, is the primary source
More informationWhat is Biotechnology?
What is Biotechnology? Biotechnology is a modern technology that makes use of organisms (or parts thereof) to: make or modify products; improve and develop microorganisms, plants or animals; or develop
More informationUNIT 3: GENETICS Chapter 9: Frontiers of Biotechnology
CORNELL NOTES Directions: You must create a minimum of 5 questions in this column per page (average). Use these to study your notes and prepare for tests and quizzes. Notes will be stamped after each assigned
More informationDNA/RNA STUDY GUIDE. Match the following scientists with their accomplishments in discovering DNA using the statement in the box below.
Name: Period: Date: DNA/RNA STUDY GUIDE Part A: DNA History Match the following scientists with their accomplishments in discovering DNA using the statement in the box below. Used a technique called x-ray
More informationGenetic Engineering Challenge How can scientists develop a type of rice that could prevent vitamin A deficiency? 1
Genetic Engineering Challenge How can scientists develop a type of rice that could prevent vitamin A deficiency? 1 Vitamin A deficiency can result in blindness, severe infectious diseases, and even death,
More informationFig Ch 17: From Gene to Protein
Fig. 17-1 Ch 17: From Gene to Protein Basic Principles of Transcription and Translation RNA is the intermediate between genes and the proteins for which they code Transcription is the synthesis of RNA
More informationM I C R O B I O L O G Y WITH DISEASES BY TAXONOMY, THIRD EDITION
M I C R O B I O L O G Y WITH DISEASES BY TAXONOMY, THIRD EDITION Chapter 7 Microbial Genetics Lecture prepared by Mindy Miller-Kittrell, University of Tennessee, Knoxville The Structure and Replication
More information2 Gene Technologies in Our Lives
CHAPTER 15 2 Gene Technologies in Our Lives SECTION Gene Technologies and Human Applications KEY IDEAS As you read this section, keep these questions in mind: For what purposes are genes and proteins manipulated?
More information2.4 TYPES OF MICROBIAL CULTURE
2.4 TYPES OF MICROBIAL CULTURE Microbial culture processes can be carried out in different ways. There are three models of fermentation used in industrial applications: batch, continuous and fed batch
More informationDNA Structure and Replication, and Virus Structure and Replication Test Review
DNA Structure and Replication, and Virus Structure and Replication Test Review What does DNA stand for? Deoxyribonucleic Acid DNA is what type of macromolecule? DNA is a nucleic acid The building blocks
More informationBiosafety Training NIH Guidelines for Research Involving Recombinant DNA. About the Course. Who Should Complete this Course?
Biosafety Training NIH Guidelines for Research Involving Recombinant DNA The University of Iowa Date(s) Revised: 01/2012 NIH GUIDELINES FOR RESEARCH INVOLVING RECOMBINANT DNA MOLECULES (NIH GUIDELINES)
More informationBiotechnology. Chapter 13
Biotechnology Chapter 13 Genetic Changes Humans have been changing the genetics of other species for thousands of years Artificial selection of plants and animals Tomato plants look nothing like their
More informationCOMMITTEE FOR VETERINARY MEDICINAL PRODUCTS NOTE FOR GUIDANCE 1 : DNA VACCINES NON-AMPLIFIABLE IN EUKARYOTIC CELLS FOR VETERINARY USE
The European Agency for the Evaluation of Medicinal Products Evaluation of Medicines for Veterinary Use CVMP/IWP/07/98-FINAL COMMITTEE FOR VETERINARY MEDICINAL PRODUCTS NOTE FOR GUIDANCE 1 : DNA VACCINES
More informationTest Prep Pretest. in the. the. whereas prokaryotic DNA contains only replication forks during replication. Skills Worksheet
Skills Worksheet Test Prep Pretest Complete each statement by writing the correct term or phrase in the space provided. 1. In 1928, Frederick Griffith found that the capsule that enclosed one strain of
More informationSTUDY GUIDE SECTION 10-1 Discovery of DNA
STUDY GUIDE SECTION 10-1 Discovery of DNA Name Period Date Multiple Choice-Write the correct letter in the blank. 1. The virulent strain of the bacterium S. pneumoniae causes disease because it a. has
More informationGM (Genetically Modified) Plants. Background
1 GM (Genetically Modified) Plants Background Genetically modified crops (GM) have been used since 1996 in the U.S. GM crops contain foreign genetic material The DNA may be from another plant or from a
More informationDNA Technology. B. Using Bacteria to Clone Genes: Overview:
DNA Technology A. Basic Vocabulary: is DNA from 2 different sources that is combined. is the direct manipulation of genes for practical purposes. literally means or in a test tube or flask. is the manipulation
More informationManipulating DNA. Nucleic acids are chemically different from other macromolecules such as proteins and carbohydrates.
Lesson Overview 14.3 Studying the Human Genome Nucleic acids are chemically different from other macromolecules such as proteins and carbohydrates. Nucleic acids are chemically different from other macromolecules
More informationProkaryotic Transcription
Prokaryotic Transcription Transcription Basics DNA is the genetic material Nucleic acid Capable of self-replication and synthesis of RNA RNA is the middle man Nucleic acid Structure and base sequence are
More informationWhat Are the Chemical Structures and Functions of Nucleic Acids?
THE NUCLEIC ACIDS What Are the Chemical Structures and Functions of Nucleic Acids? Nucleic acids are polymers specialized for the storage, transmission, and use of genetic information. DNA = deoxyribonucleic
More informationIPs on sequences. Sunil Archak
IPs on sequences Sunil Archak Need to ensure conducting research without infringing upon others IP rights Need to defend own IP rights against other users Justify the substantial costs involved in research
More informationCROP PRODUCTION AND BIOTECHNOLOGY: Successes and Challenges SUMMARY
CROP PRODUCTION AND BIOTECHNOLOGY: Successes and Challenges SUMMARY Background Different scientists have defined the term biotechnology. These definitions reflect the particular perspective of the scientists.
More informationReview of Protein (one or more polypeptide) A polypeptide is a long chain of..
Gene expression Review of Protein (one or more polypeptide) A polypeptide is a long chain of.. In a protein, the sequence of amino acid determines its which determines the protein s A protein with an enzymatic
More informationB.Sc. MICROBIOLOGY SYLLABUS DDU GORAKHPUR UNIVERSITY, GORAKHPUR Industrial Microbiology D. D. U. Gorakhpur University, Gorakhpur B.Sc.
Industrial Microbiology D. D. U. Gorakhpur University, Gorakhpur B.Sc. III B.Sc. II: Three papers and a practical examination as follows: Paper I: Food Microbiology Papers II: Fermentation Technology Papers
More informationLecture 3 (FW) January 28, 2009 Cloning of DNA; PCR amplification Reading assignment: Cloning, ; ; 330 PCR, ; 329.
Lecture 3 (FW) January 28, 2009 Cloning of DNA; PCR amplification Reading assignment: Cloning, 240-245; 286-87; 330 PCR, 270-274; 329. Take Home Lesson(s) from Lecture 2: 1. DNA is a double helix of complementary
More informationDNA, RNA, PROTEIN SYNTHESIS, AND MUTATIONS UNIT GUIDE Due December 9 th. Monday Tuesday Wednesday Thursday Friday 16 CBA History of DNA video
DNA, RNA, PROTEIN SYNTHESIS, AND MUTATIONS UNIT GUIDE Due December 9 th Monday Tuesday Wednesday Thursday Friday 16 CBA History of DNA video 17 History of DNA 18 Lecture: DNA Structure Worksheet 19 Lecture:
More informationREGULATION OF GENE EXPRESSION
REGULATION OF GENE EXPRESSION Each cell of a living organism contains thousands of genes. But all genes do not function at a time. Genes function according to requirements of the cell. Genes control the
More informationGenetic Engineering Methods
Genetic Engineering Methods Outline Why do it? Research examples: poplar trees Plant gene transfer concepts and methods Getting genes ready for transfer (recombinant DNA/plasmids) Analysis of transgenic
More informationGene Transfer 11/4/13. Fredrick Griffith in the 1920s did an experiment. Not until 1944 was DNA shown to be the moveable element
Gene Transfer Fredrick Griffith in the 1920s did an experiment. Not until 19 was DN shown to be the moveable element Dead pathogen cells able to make a capsule were able to pass this ability to the live
More informationProtein Synthesis
HEBISD Student Expectations: Identify that RNA Is a nucleic acid with a single strand of nucleotides Contains the 5-carbon sugar ribose Contains the nitrogen bases A, G, C and U instead of T. The U is
More informationDNA & DNA Replication
DNA & DNA Replication DNA Structure How did Watson and Crick contribute to our understanding of genetics? Watson and Crick developed the double helix model for DNA DNA Structure What is a double helix?
More informationNucleic acids deoxyribonucleic acid (DNA) ribonucleic acid (RNA) nucleotide
Nucleic Acids Nucleic acids are molecules that store information for cellular growth and reproduction There are two types of nucleic acids: - deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) These
More informationAugust Green Biotechnology Peter Oakley Member of the Board of Executive Directors
August 2005 Green Biotechnology Peter Oakley Member of the Board of Executive Directors 1 Biotechnology & Markets 2 Focus of BASF Strategy 3 Research Platform 4 Business Model 5 Pipeline 6 Beyond Green
More informationSpostiamo ora la nostra attenzione sui batteri, e batteriofagi
Spostiamo ora la nostra attenzione sui batteri, e batteriofagi Bacteria Mutate Spontaneously and Grow at an Exponential Rate. Useful for genetics studies, development of genetic engineering Teoria dell'adattamento
More informationSequence Analysis Lab Protocol
Sequence Analysis Lab Protocol You will need this handout of instructions The sequence of your plasmid from the ABI The Accession number for Lambda DNA J02459 The Accession number for puc 18 is L09136
More informationFuture Biotechnology Products and Opportunities to Enhance the Capabilities of the Biotechnology Regulatory System
Future Biotechnology Products and Opportunities to Enhance the Capabilities of the Biotechnology Regulatory System June 2016 Synthetic Biology at Modular Genetics The Future of Chemical Manufacturing and
More informationColor-Switch CRE recombinase stable cell line
Color-Switch CRE recombinase stable cell line Catalog Number Product Name / Description Amount SC018-Bsd CRE reporter cell line (Bsd): HEK293-loxP-GFP- RFP (Bsd). RFP" cassette with blasticidin antibiotic
More informationShipping Biological Materials Quick Reference Guide
* This document provides UC Berkeley researchers a quick overview of government requirements and internal policy for transporting biological materials, either to or from campus. For additional information
More information